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WO2001028614A1 - Nebuliseur capillaire possedant des canaux traversants dans la plaque capillaire - Google Patents

Nebuliseur capillaire possedant des canaux traversants dans la plaque capillaire Download PDF

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Publication number
WO2001028614A1
WO2001028614A1 PCT/US2000/027951 US0027951W WO0128614A1 WO 2001028614 A1 WO2001028614 A1 WO 2001028614A1 US 0027951 W US0027951 W US 0027951W WO 0128614 A1 WO0128614 A1 WO 0128614A1
Authority
WO
WIPO (PCT)
Prior art keywords
nebulizer
capillary feed
plate
bottom plate
channels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/027951
Other languages
English (en)
Inventor
Chau B. Tran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teleflex Medical Inc
Original Assignee
Hudson Respiratory Care Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hudson Respiratory Care Inc filed Critical Hudson Respiratory Care Inc
Priority to AU10766/01A priority Critical patent/AU1076601A/en
Publication of WO2001028614A1 publication Critical patent/WO2001028614A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/0012Apparatus for achieving spraying before discharge from the apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/24Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas with means, e.g. a container, for supplying liquid or other fluent material to a discharge device
    • B05B7/2402Apparatus to be carried on or by a person, e.g. by hand; Apparatus comprising containers fixed to the discharge device
    • B05B7/2405Apparatus to be carried on or by a person, e.g. by hand; Apparatus comprising containers fixed to the discharge device using an atomising fluid as carrying fluid for feeding, e.g. by suction or pressure, a carried liquid from the container to the nozzle
    • B05B7/2435Apparatus to be carried on or by a person, e.g. by hand; Apparatus comprising containers fixed to the discharge device using an atomising fluid as carrying fluid for feeding, e.g. by suction or pressure, a carried liquid from the container to the nozzle the carried liquid and the main stream of atomising fluid being brought together by parallel conduits placed one inside the other

Definitions

  • Flat bottom capillary feed nebulizers have an advantage over other capillary feed respiratory nebulizers in delivering aerosol while being held at an angle or tilted from vertical with little or no interruption of liquid flow from the liquid reservoir to the gas mixing chamber.
  • the Hudson RCI M ⁇ crom ⁇ st w Small Volume Nebulizer is a capillary feed nebulizer designed to deliver a fine, dense mist at any angle up to 90° tilt from vertical.
  • Such a feature allows the clinician to administer medications to patients with special treatment requirements which may cause the nebulizer to be tilted at an angle relative to vertical
  • the aforesaid nebulizer is described in U.S. Patent No. Re 33,642
  • the improved capillary feed nebulizer of the present invention incorporates a capillary feed plate having a plurality of channels extending along the upper and lower plate surface and communicating the liquid holding chamber of the nebulizer jar with the capillary feed passageway These channels provide sufficient paths for liquid medication which could otherwise remain on the upper surface of the capillary feed plate as previously described.
  • Fig 1 is a side elevational view of the nebulizer of the invention illustrating the relationship of the assembled spray nozzle and capillary feed plate
  • Figs. 2 and 3 are upper and lower perspective views, respectfully, of an integral spray nozzle and channeled capillary feed plate of the invention.
  • Figs. 4 and 5 are top plan views of capillary feed plates showing examples of alternative channel design embodiments. Detailed Description of the Invention
  • Fig. 1 illustrating the assembled liquid and gas directing components of a capillary feed nebulizer of the invention
  • the general structure and features of the capillary feed components of the device are similar to those disclosed and shown in U.S Patent Re. 33,642
  • These basic components include a gas pipe 17 which extends downwardly from bottom plate 15 and gas nozzle 18 The gas pipe will be connected to a gas supply tube when the nebulizer is in use.
  • a nebulizer jar 11 includes a sidewall 14, the upper portion of which defines a liquid holding chamber 20
  • Sidewall 14, bottom plate 15, gas nozzle 18 and gas pipe 17 may be integrally formed and molded as one piece, or two or more of the components independently formed and assembled, using adhesives or otherwise bonded together such as by ultrasonic bonding or other techniques known in the art
  • the components are conveniently molded as one piece using a thermoplastic resin such as polypropylene, polyethylene, polyvmyl chloride, or other equivalent and suitable polymers or plastics
  • gas nozzle 18 extends along a substantially vertical axis from the plane of bottom plate 15, the latter illustrated as a flat plate extending along a plane normal to the gas nozzle axis
  • bottom plate 15 may be slanted upwardly or downwardly from such a normal plane relative to the axis of gas nozzle 18, preferably at an angle of J- about 30°, and preferably of less than about ⁇ 15°
  • the bottom plate need not be flat or planar, but may be curved or arched along its upper surface.
  • the upper surface of the bottom plate is substantially flat, more preferably lying along a plane substantially normal to the central axis of gas nozzle 18.
  • the spray nozzle 30 and capillary feed plate 32 are illustrated
  • the two components are integrally formed, such as by a single molding operation using a suitable thermoplastic such as previously described or they may be separately formed and assembled using adhesive or ultrasonic welding or similar and equivalent techniques known in the art.
  • the shape of the interior surface of the spray nozzle 30 is such that when the spray nozzle is assembled to overlie gas nozzle 18 as shown in Fig. 1 , a liquid flow passageway 21 is provided for directing liquid supplied from the liquid holding chamber to a gas/liquid mixing chamber 23.
  • the interior surface of spray nozzle 30 may be cylindrical and spaced apart from the outer surface of gas nozzle 18 along its entire length, or either or both of the two surfaces may be formed to create a plurality of fluid passageways.
  • the interior surface of spray nozzle 30 may have one or more surfaces which contact the exterior surface of gas nozzle 18 thereby creating a plurality of fluid passageways along a portion or all of the length between the two surfaces
  • the passageway dimensions will be such that liquid will be drawn upwardly along liquid flow passageway 21 to the mixing chamber 23 when gas is supplied to gas pipe 17 and forced through gas port 13, across mixing chamber 23 and out through spray port 19.
  • the bottom surface 35 of capillary feed plate 32 overlies the upper surface 22 of bottom plate 15 to form a capillary feed passageway 33 therebetween.
  • the lower surface 35 of the capillary feed plate 32 is parallel with the upper surface 22 of bottom plate 15 so that the capillary feed passageway 35 is substantially uniform in its dimension between the two surfaces.
  • some variation other than parallel surfaces is acceptable, so long as a capillary feed of the liquid along the capillary feed passageway is provided and maintained during operation of the nebulizer.
  • the angle between the plane along which capillary feed plate 32 lies relative to the central axis of spray nozzle 30 will preferably be the same as the relative angle between the plane of bottom plate 15 and the central axis of gas nozzle 18 Moreover, as is shown in Fig 1 , the gas nozzle and spray nozzle are coaxial when assembled Accordingly, most preferably, a capillary feed plate lies along a plane normal to the central axis of spray nozzle 30, or along a plane at an angle of i 30° or less and preferably less than t 15° from the axis of spray nozzle 30.
  • capillary feed plate 32 also preferably lies along a normal plane relative to the axis of spray nozzle 30. Moreover, where the upper surface of the bottom plate is curved or arched, the bottom surface of the capillary feed plate is also curved or arched. Similarly, any departure of the angle of the plane of bottom plate 15 relative to the axis of a gas nozzle will be reflected in the angle of the plane of capillary feed plate 32 relative to the axis of spray nozzle 30, whereby the upper surface of bottom plate 15 and lower surface of capillary feed plate 32 are substantially parallel to define a substantially uniform capillary feed passageway as previously described
  • gas is directed into gas pipe 17 from an external gas source, not shown, and upwardly through the pipe into the interior of gas nozzle 18. From there the gas passes through the gas port 13, and across mixing chamber 23 to create an aerosol which is forced out of spray port 19.
  • the liquid medication to be nebulized is charged into liquid holding chamber 20.
  • a vacuum is created in mixing chamber 23 causing liquid to rise along passageway 21.
  • the liquid is supplied from chamber 20 through liquid flow inlet 26, slot 31 and capillary feed passageway 33.
  • the liquid flow inlet 26 is defined between the edge of capillary feed plate 32 and the nebulizer jar sidewall 14 which defines the liquid holding chamber 20.
  • a slot 31 is defined by a space between adjacent ribs 28 which are positioned around the periphery of the capillary feed plate 32 and extend from the lower or bottom surface of the capillary feed plate. Accordingly, a plurality of slots are provided, the specific number of which slots and ribs is not critical so long as a sufficient number are present to adequately supply liquid to the capillary feed passageway. However, the dimensions of the ribs, particularly their thickness, is important in maintaining the proper spacing or separation of the bottom surface of the capillary feed plate from the upper surface 22 of the bottom plate which space forms the capillary feed passageway as previously described.
  • a plurality of channels 25 are formed and extend through the capillary feed plate to communicate the liquid holding chamber 20 with capillary feed passageway 33 to improve the performance of the apparatus of the invention.
  • a small amount of the liquid for example, up to about two milli ters or more, can remain on the upper surface of the capillary feed plate, particularly when the nebulizer is held in a vertical position.
  • channels 25 present on the upper surface of the capillary feed plate liquid on the plate surface will pass into the channels and be directed to the capillary feed passageway 33.
  • the channels are preferably uniformly spaced apart on the capillary feed plate, and in the embodiment shown in Figs.
  • radial channels 25 extend at least half of the distance from the outer edge of the capillary feed plate to the spray nozzle
  • the number of such channels is between 4 and 16, and more preferably is 8 or more.
  • Figs. 4 and 5 illustrate examples of alternative channel embodiments within the scope of the invention.
  • channels 29 are shown as arc shaped segments of concentric rings on the capillary feed plate 32.
  • the channels comprise a series of round holes or ports aligned along radial axes.
  • Such ports need not be circular and may have other desirable shapes and be spaced apart in other patterns or randomly spaced, as may the plurality of channels, so long as they do not interfere with the performance of the capillary feed passageway to adequately and sufficiently direct liquid from the liquid holding chamber to the liquid flow passageway. Combinations of different channel shapes, patterns and spacing may also be used.
  • baffle, target or impingement surface design may be used, for example, as disclosed in the aforesaid patents, as well as U.S Patent No 3,762,409.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nozzles (AREA)

Abstract

L'invention concerne un nébuliseur capillaire faisant intervenir une plaque capillaire possédant une pluralité de canaux qui s'étendent le long de la plaque, entre la surface supérieure et la surface inférieure de la plaque.
PCT/US2000/027951 1999-10-15 2000-10-11 Nebuliseur capillaire possedant des canaux traversants dans la plaque capillaire Ceased WO2001028614A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU10766/01A AU1076601A (en) 1999-10-15 2000-10-11 Capillary feed nebulizers having through channels in the capillary feed plate

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41927099A 1999-10-15 1999-10-15
US09/419,270 1999-10-15

Publications (1)

Publication Number Publication Date
WO2001028614A1 true WO2001028614A1 (fr) 2001-04-26

Family

ID=23661539

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/027951 Ceased WO2001028614A1 (fr) 1999-10-15 2000-10-11 Nebuliseur capillaire possedant des canaux traversants dans la plaque capillaire

Country Status (2)

Country Link
AU (1) AU1076601A (fr)
WO (1) WO2001028614A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011073756A3 (fr) * 2009-12-15 2011-08-11 Artsana S.P.A. Nébuliseur comportant un nombre réduit de composants

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE33642E (en) * 1982-11-22 1991-07-23 Hudson Oxygen Therapy Sales Company Nebulizer with capillary feed
FR2660636A1 (fr) * 1990-04-04 1991-10-11 Dp Medical Reservoir d'atomiseur.
WO1992015354A1 (fr) * 1991-02-28 1992-09-17 Intersurgical Limited Nebuliseur
US5738086A (en) * 1994-02-02 1998-04-14 Baxter International Inc. Method of installing an anti-siphon flow restricter for a nebulizer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE33642E (en) * 1982-11-22 1991-07-23 Hudson Oxygen Therapy Sales Company Nebulizer with capillary feed
FR2660636A1 (fr) * 1990-04-04 1991-10-11 Dp Medical Reservoir d'atomiseur.
WO1992015354A1 (fr) * 1991-02-28 1992-09-17 Intersurgical Limited Nebuliseur
US5738086A (en) * 1994-02-02 1998-04-14 Baxter International Inc. Method of installing an anti-siphon flow restricter for a nebulizer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011073756A3 (fr) * 2009-12-15 2011-08-11 Artsana S.P.A. Nébuliseur comportant un nombre réduit de composants
CN102655901A (zh) * 2009-12-15 2012-09-05 阿特萨纳公司 具有减小的数量的部件的喷雾器

Also Published As

Publication number Publication date
AU1076601A (en) 2001-04-30

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