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WO2001028539A3 - Agent for treating cephalic pain - Google Patents

Agent for treating cephalic pain Download PDF

Info

Publication number
WO2001028539A3
WO2001028539A3 PCT/GB2000/004031 GB0004031W WO0128539A3 WO 2001028539 A3 WO2001028539 A3 WO 2001028539A3 GB 0004031 W GB0004031 W GB 0004031W WO 0128539 A3 WO0128539 A3 WO 0128539A3
Authority
WO
WIPO (PCT)
Prior art keywords
agent
cephalic pain
treating cephalic
treating
insulin receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2000/004031
Other languages
French (fr)
Other versions
WO2001028539A9 (en
WO2001028539A2 (en
Inventor
Ian James Purvis
Linda Catherine Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9924713.2A external-priority patent/GB9924713D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to AU10368/01A priority Critical patent/AU1036801A/en
Publication of WO2001028539A2 publication Critical patent/WO2001028539A2/en
Publication of WO2001028539A9 publication Critical patent/WO2001028539A9/en
Anticipated expiration legal-status Critical
Publication of WO2001028539A3 publication Critical patent/WO2001028539A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Use of an agent that modulates directly or indirectly the insulin receptor or insulin receptor signalling pathway in the manufacture of a medicament for use in a method of preventing or treating cephalic pain.
PCT/GB2000/004031 1999-10-19 2000-10-19 Agent for treating cephalic pain Ceased WO2001028539A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU10368/01A AU1036801A (en) 1999-10-19 2000-10-19 Agent for treating cephalic pain

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16042399P 1999-10-19 1999-10-19
US60/160,423 1999-10-19
GBGB9924713.2A GB9924713D0 (en) 1999-10-19 1999-10-19 Therapy
GB9924713.2 1999-10-19

Publications (3)

Publication Number Publication Date
WO2001028539A2 WO2001028539A2 (en) 2001-04-26
WO2001028539A9 WO2001028539A9 (en) 2002-02-07
WO2001028539A3 true WO2001028539A3 (en) 2002-09-12

Family

ID=26316012

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/004031 Ceased WO2001028539A2 (en) 1999-10-19 2000-10-19 Agent for treating cephalic pain

Country Status (2)

Country Link
AU (1) AU1036801A (en)
WO (1) WO2001028539A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0025678D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Diagnostic test
NO20031157L (en) * 2002-03-18 2003-09-19 Jenapharm Gmbh Method of Identifying a Pharmaceutically Active Compound for the Treatment of a Condition Caused by Altered Expression of the Insulin Receptor
US20120183966A1 (en) * 2010-11-22 2012-07-19 Harrington Sean C Detection and quantitation of insulin receptor alpha isoform or beta isoform

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0440333A2 (en) * 1990-01-10 1991-08-07 Louisiana State University Agricultural And Mechanical College Dopamine agonists for treating type II diabetes
US5677279A (en) * 1996-12-16 1997-10-14 Amylin Pharmaceuticals, Inc. Methods and compositions for treating pain with amylin or agonists thereof
US5902726A (en) * 1994-12-23 1999-05-11 Glaxo Wellcome Inc. Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma
WO2000053601A1 (en) * 1999-03-08 2000-09-14 The University Of Mississippi 1,2-dithiolane derivatives
WO2001029256A2 (en) * 1999-10-19 2001-04-26 Glaxo Group Limited Cephalic pain susceptibility marker

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0440333A2 (en) * 1990-01-10 1991-08-07 Louisiana State University Agricultural And Mechanical College Dopamine agonists for treating type II diabetes
US5902726A (en) * 1994-12-23 1999-05-11 Glaxo Wellcome Inc. Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma
US5677279A (en) * 1996-12-16 1997-10-14 Amylin Pharmaceuticals, Inc. Methods and compositions for treating pain with amylin or agonists thereof
WO2000053601A1 (en) * 1999-03-08 2000-09-14 The University Of Mississippi 1,2-dithiolane derivatives
WO2001029256A2 (en) * 1999-10-19 2001-04-26 Glaxo Group Limited Cephalic pain susceptibility marker

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
"THE MERCK INDEX", 1996, MERCK & CO., WHITEHOUSE STATION, NJ, XP002178774 *
B. COULIE ET AL.: "5-Hydroxytryptamine-1 receptor activation inhibits endocrine pancreatic secretion in humans", AMERICAN JOURNAL OF PHYSIOLOGY, vol. 274, 1998, pages E317 - E320, XP001028532 *
FEUERSTEIN G ET AL: "Clinical perspectives of calcitonin gene related peptide pharmacology.", CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, (1995 JUL) 73 (7) 1070-4 REF: 24, XP001028136 *
J.N. BLAU ET AL.: "EFFECT OF DIABETES ON MIGRAINE", LANCET, vol. 2, no. 7666, 1970, pages 241 - 243, XP001028145 *
POLONI M ET AL: "Insulin secretion in migraine: influence on the blood levels of tryptophan.", MONOGRAPHS IN NEURAL SCIENCES, (1976) 3 67-70., XP001028149 *
W. SPLIT ET AL.: "HEADACHES IN NON INSULIN-DEPENDENT DIABETES MELLITUS", FUNCTIONAL NEUROLOGY, vol. 12, no. 6, 1997, pages 327 - 332, XP001028137 *

Also Published As

Publication number Publication date
WO2001028539A9 (en) 2002-02-07
WO2001028539A2 (en) 2001-04-26
AU1036801A (en) 2001-04-30

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