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WO2001019860A3 - Proteines associees a la differenciation cellulaire - Google Patents

Proteines associees a la differenciation cellulaire Download PDF

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Publication number
WO2001019860A3
WO2001019860A3 PCT/US2000/025435 US0025435W WO0119860A3 WO 2001019860 A3 WO2001019860 A3 WO 2001019860A3 US 0025435 W US0025435 W US 0025435W WO 0119860 A3 WO0119860 A3 WO 0119860A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell differentiation
cdiff
proteins associated
provides
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/025435
Other languages
English (en)
Other versions
WO2001019860A2 (fr
Inventor
Y Tom Tang
Jennifer L Hillman
Henry Yue
Roopa Reddy
Preeti Lal
Purvi Shah
Yalda Azimzai
Mariah R Baughn
Dyung Aina M Lu
Olga Bandman
Leo L Shih
Chandra Patterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to JP2001523637A priority Critical patent/JP2003527092A/ja
Priority to CA002384324A priority patent/CA2384324A1/fr
Priority to AU74942/00A priority patent/AU7494200A/en
Priority to EP00963541A priority patent/EP1214337A2/fr
Publication of WO2001019860A2 publication Critical patent/WO2001019860A2/fr
Publication of WO2001019860A3 publication Critical patent/WO2001019860A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
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    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
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Abstract

L'invention concerne des protéines humaines impliquées dans la différenciation cellulaire (CDIFF) et des polynucléotides identifiant et codant ces protéines CDIFF. Elle concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Cette invention se rapporte en outre à des méthodes permettant de diagnostiquer, de traiter ou de prévenir les troubles associés à l'expression des protéines CDIFF.
PCT/US2000/025435 1999-09-15 2000-09-14 Proteines associees a la differenciation cellulaire Ceased WO2001019860A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001523637A JP2003527092A (ja) 1999-09-15 2000-09-14 細胞分化に関与するタンパク質
CA002384324A CA2384324A1 (fr) 1999-09-15 2000-09-14 Proteines associees a la differenciation cellulaire
AU74942/00A AU7494200A (en) 1999-09-15 2000-09-14 Proteins associated with cell differentiation
EP00963541A EP1214337A2 (fr) 1999-09-15 2000-09-14 Proteines associees a la differenciation cellulaire

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15414099P 1999-09-15 1999-09-15
US60/154,140 1999-09-15
US16915599P 1999-12-06 1999-12-06
US60/169,155 1999-12-06

Publications (2)

Publication Number Publication Date
WO2001019860A2 WO2001019860A2 (fr) 2001-03-22
WO2001019860A3 true WO2001019860A3 (fr) 2002-01-24

Family

ID=26851183

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/025435 Ceased WO2001019860A2 (fr) 1999-09-15 2000-09-14 Proteines associees a la differenciation cellulaire

Country Status (5)

Country Link
EP (1) EP1214337A2 (fr)
JP (1) JP2003527092A (fr)
AU (1) AU7494200A (fr)
CA (1) CA2384324A1 (fr)
WO (1) WO2001019860A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534112A (ja) 1999-01-15 2002-10-15 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド 骨髄特異的タンパク質
DE10007468A1 (de) * 2000-02-18 2001-08-23 Basf Lynx Bioscience Ag Neues zentralnervöses Protein, das K·+·-Ströme moduliert
EP1130030A1 (fr) * 2000-03-02 2001-09-05 Roche Diagnostics Corporation Facteur associé à la différentiation érytroide
GB0026604D0 (en) 2000-10-31 2000-12-13 Roslin Inst Edinburgh Diagnostic method
WO2002036781A2 (fr) * 2000-10-31 2002-05-10 Bayer Aktiengesellschaft Regulation de la glutathione-s-transferase humaine
CA2504920C (fr) * 2004-05-14 2014-04-01 Euroscreen S.A. Ligand pour recepteur fprl2 couple aux proteines g et leur utilisation
JP5891561B2 (ja) * 2011-06-03 2016-03-23 学校法人自治医科大学 ミトコンドリア膜タンパク質群およびそれらをコードする遺伝子群

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739009A (en) * 1996-12-12 1998-04-14 Incyte Pharmaceuticals, Inc. Adipocyte-specific differentiation-related protein
WO1998041634A1 (fr) * 1997-03-20 1998-09-24 Incyte Pharmaceuticals, Inc. Proteine de differenciation et de croissance humaine
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739009A (en) * 1996-12-12 1998-04-14 Incyte Pharmaceuticals, Inc. Adipocyte-specific differentiation-related protein
WO1998041634A1 (fr) * 1997-03-20 1998-09-24 Incyte Pharmaceuticals, Inc. Proteine de differenciation et de croissance humaine
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
ABDELHAK S ET AL: "A HUMAN HOMOLOGUE OF THE DROSOPHILA EYES ABSENT GENE UNDERLIES BRANCHIO-OTO-RENAL (BOR) SYNDROME AND IDENTIFIES A NOVEL GENE FAMILY", NATURE GENETICS,US,NEW YORK, NY, vol. 15, no. 2, 1 February 1997 (1997-02-01), pages 157 - 164, XP002071634, ISSN: 1061-4036 *
FUJIWARA, T.: "Human fetal brain cDNA 5'-end GEN-413E12", EMBL SEQUENCE DATABASE, 29 September 1996 (1996-09-29), HEIDELBERG DE, XP002163341 *
HILLIER ET AL.: "au43h04.y1 Schneider fetal brain 00004 Homo sapiens cDNA clone IMAGE:2517559 3' similar to TR:O88741 O88741 GANGLIOSIDE-INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 1. ;, mRNA sequence", EMBL SEQUENCE DATABASE, 12 July 1999 (1999-07-12), HEIDELBERG DE, XP002163340 *
HILLIER ET AL.: "au43h04.y1 Schneider fetal brain 00004 Homo sapiens cDNA clone IMAGE:2517559 5' similar to TR:O88741 O88741 GANGLIOSIDE-INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 1. ;, mRNA sequence", EMBL SEQUENCE DATABASE, 12 July 1999 (1999-07-12), HEIDELBERG DE, XP002163339 *
HOLMES G P ET AL: "DISCTINCT BUT OVERLAPPING EXPRESSION PATTERNS OF TWO VERTEBRATE SLIT HOMOLOGS IMPLIES FUNCTIONAL ROLES IN CNS DEVELOPMENT AND ORGANOGENESIS", MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE IRELAND LTD,IE, vol. 79, 1998, pages 57 - 72, XP000912208, ISSN: 0925-4773 *
LIU ET AL.: "Homo sapiens mRNA for ganglioside-induced differentiation associated protein 1", EMBL SEQUENCE DATABASE, 31 July 1998 (1998-07-31), HEIDELBERG DE, XP002163336 *
LIU ET AL.: "Isolation of 10 differentially expressed cDNAs in differentiated Nuro2a cells induced through controlled expression of the GD3 synthase gene", JOURNAL OF NEUROCHEMISTRY, vol. 72, 1999, pages 1781 - 1790, XP000992245 *
NCI-CGAP: "wg81e08.x1 Soares_NSF_F8_9W_OT_PA_P_S1 Homo sapiens cDNA clone IMAGE:2371526 3' similar to TR:O88741 O88741 GANGLIOSIDE-INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 1. ;, mRNA sequence", EMBL SEQUENCE DATABASE, 30 June 1999 (1999-06-30), HEIDELBERG DE, XP002163337 *
NCI-CGAP: "wg81f07.x1 Soares_NSF_F8_9W_OT_PA_P_S1 Homo sapiens cDNA clone IMAGE:2371525 3' similar to TR:O88741 O88741 GANGLIOSIDE-INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 1. ;, mRNA sequence", EMBL SEQUENCE DATABASE, 30 June 1999 (1999-06-30), HEIDELBERG DE, XP002163338 *

Also Published As

Publication number Publication date
CA2384324A1 (fr) 2001-03-22
WO2001019860A2 (fr) 2001-03-22
JP2003527092A (ja) 2003-09-16
AU7494200A (en) 2001-04-17
EP1214337A2 (fr) 2002-06-19

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