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WO2001019335A3 - Compositions destinees a une administration par voie muqueuse - Google Patents

Compositions destinees a une administration par voie muqueuse Download PDF

Info

Publication number
WO2001019335A3
WO2001019335A3 PCT/FR2000/002523 FR0002523W WO0119335A3 WO 2001019335 A3 WO2001019335 A3 WO 2001019335A3 FR 0002523 W FR0002523 W FR 0002523W WO 0119335 A3 WO0119335 A3 WO 0119335A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
mucous membrane
administered
antigen
mucous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2000/002523
Other languages
English (en)
Other versions
WO2001019335A2 (fr
Inventor
Sophie Gaubert
Rene Laversanne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Capsulis SA
Original Assignee
Capsulis SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Capsulis SA filed Critical Capsulis SA
Priority to CA002384876A priority Critical patent/CA2384876A1/fr
Priority to JP2001522970A priority patent/JP2003509352A/ja
Priority to AU74284/00A priority patent/AU782653B2/en
Priority to EP00962621A priority patent/EP1212043A2/fr
Publication of WO2001019335A2 publication Critical patent/WO2001019335A2/fr
Publication of WO2001019335A3 publication Critical patent/WO2001019335A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne une nouvelle utilisation de vésicules multilamellaires à structure en oignon présentant une structure interne cristal-liquide formée d'un empilement de bicouches concentriques à base d'agents amphiphiles alternant avec des couches d'eau, de solution aqeuse ou de solution d'un liquide polaire et au sein desquelles se trouve incorporé au moins un antigène, pour la fabrication d'une composition notamment pharmaceutique et plus particulièrement vaccinale destinée à une administration par voix muquese pour induire une réponse muqueuse et/ou systémique sérique et/ou pour protéger l'organisme à l'égard de l'infection dont est responsable ledit antigène. L'invention concerne également un procédé de vaccination par voie muqueuse et un procédé de production d'anticorps, notamment d'IgA. L'invention s'applique tout particulièrement dans le cas d'une administration par voie nasale.
PCT/FR2000/002523 1999-09-14 2000-09-13 Compositions destinees a une administration par voie muqueuse Ceased WO2001019335A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002384876A CA2384876A1 (fr) 1999-09-14 2000-09-13 Compositions destinees a une administration par voie muqueuse
JP2001522970A JP2003509352A (ja) 1999-09-14 2000-09-13 粘膜を介して投与される組成物
AU74284/00A AU782653B2 (en) 1999-09-14 2000-09-13 Composition to be administered through mucous membrane
EP00962621A EP1212043A2 (fr) 1999-09-14 2000-09-13 Compositions destinees a une administration par voie muqueuse

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR99/11465 1999-09-14
FR9911465A FR2798288B1 (fr) 1999-09-14 1999-09-14 Compositions vaccinales destinees a une administration par voie muqueuse

Publications (2)

Publication Number Publication Date
WO2001019335A2 WO2001019335A2 (fr) 2001-03-22
WO2001019335A3 true WO2001019335A3 (fr) 2001-10-04

Family

ID=9549811

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2000/002523 Ceased WO2001019335A2 (fr) 1999-09-14 2000-09-13 Compositions destinees a une administration par voie muqueuse

Country Status (6)

Country Link
EP (1) EP1212043A2 (fr)
JP (1) JP2003509352A (fr)
AU (1) AU782653B2 (fr)
CA (1) CA2384876A1 (fr)
FR (1) FR2798288B1 (fr)
WO (1) WO2001019335A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2850872A1 (fr) * 2003-02-12 2004-08-13 Ethypharm Sa Composition vaccinale destinee a induire une reponse immunitaire contre le virus responsable du sida
US20070166238A1 (en) * 2003-11-29 2007-07-19 Passion For Life Healthcare Limited Composition and delivery system
FR2868951B1 (fr) * 2004-04-15 2006-07-21 Ethypharm Sa Compositions contenant ds vesicules lamellaires incorporant un principe actif peu soluble dans l'eau et produits intermediaires utiles pour leur preparation
KR20110056516A (ko) 2008-09-12 2011-05-30 크리티컬 파머수티컬스 리미티드 점막 또는 피부를 통한 치료제의 흡수 개선

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2769022A1 (fr) * 1997-09-29 1999-04-02 Capsulis Vecteurs d'antigenes et compositions therapeutiques contenant des antigenes
WO2000037053A1 (fr) * 1998-12-21 2000-06-29 Generex Pharmaceuticals Inc. Systeme de liberation de medicament a grosses molecules, dans lequel des amphiphiles en aerosol, imitant une membrane, sont utilises

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2769022A1 (fr) * 1997-09-29 1999-04-02 Capsulis Vecteurs d'antigenes et compositions therapeutiques contenant des antigenes
WO2000037053A1 (fr) * 1998-12-21 2000-06-29 Generex Pharmaceuticals Inc. Systeme de liberation de medicament a grosses molecules, dans lequel des amphiphiles en aerosol, imitant une membrane, sont utilises

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BROWNLIE, ROBERT M., ET AL.: "Stimulation of secretory antibodies against Bordetella pertussis antigens in the lungs of mice after oral or intranasal administration of liposome incorporated cell-surface antigens", MICROBIAL PATHOGENESIS, vol. 14, no. 2, February 1993 (1993-02-01), Aberdeen (GB), pages 149 - 60, XP000920597 *

Also Published As

Publication number Publication date
CA2384876A1 (fr) 2001-03-22
JP2003509352A (ja) 2003-03-11
EP1212043A2 (fr) 2002-06-12
AU7428400A (en) 2001-04-17
FR2798288B1 (fr) 2001-11-30
AU782653B2 (en) 2005-08-18
FR2798288A1 (fr) 2001-03-16
WO2001019335A2 (fr) 2001-03-22

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