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WO2001019270A1 - Systeme de catheter d'ablation cardiaque spirale - Google Patents

Systeme de catheter d'ablation cardiaque spirale Download PDF

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Publication number
WO2001019270A1
WO2001019270A1 PCT/US2000/024836 US0024836W WO0119270A1 WO 2001019270 A1 WO2001019270 A1 WO 2001019270A1 US 0024836 W US0024836 W US 0024836W WO 0119270 A1 WO0119270 A1 WO 0119270A1
Authority
WO
WIPO (PCT)
Prior art keywords
sheath
ablating element
ablating
shape
catheter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/024836
Other languages
English (en)
Inventor
David Keane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/396,959 external-priority patent/US6607520B2/en
Priority claimed from US09/539,056 external-priority patent/US6632223B1/en
Application filed by General Hospital Corp filed Critical General Hospital Corp
Priority to EP00961755A priority Critical patent/EP1223876A4/fr
Priority to JP2001522910A priority patent/JP2003522561A/ja
Priority to CA002388823A priority patent/CA2388823C/fr
Publication of WO2001019270A1 publication Critical patent/WO2001019270A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00867—Material properties shape memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00059—Material properties
    • A61B2018/00071—Electrical conductivity
    • A61B2018/00083—Electrical conductivity low, i.e. electrically insulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00107—Coatings on the energy applicator
    • A61B2018/00136—Coatings on the energy applicator with polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A61B2018/00375—Ostium, e.g. ostium of pulmonary vein or artery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1435—Spiral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1497—Electrodes covering only part of the probe circumference
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/821—Ostial stents

Definitions

  • the present invention relates generally to catheter systems, and more particularly, to catheter systems for ablating and/or isolating foci that contribute to cardiac arrhythmia.
  • Catheters are commonly used in surgical procedures to access certain areas of a patient's body without resorting to invasive surgical procedures.
  • catheters are widely used in the field of cardiology to conduct electrophysiological studies in which electrical potentials within the heart are mapped to determine the cause and location of arrhythmia.
  • certain undesired conductive pathways known as foci, contribute to and cause the arrhythmia.
  • foci certain undesired conductive pathways, known as foci, contribute to and cause the arrhythmia.
  • elements on or within the catheter can be utilized to ablate or isolate the foci, thus eliminating the arrhythmia.
  • U.S. Patent No. 5,476,495 discloses a steerable catheter system that is able to conduct cardiac mapping and ablation.
  • U.S. Patent No. 5,507,743 discloses a radio frequency (RF) treatment apparatus that includes a RF electrode that assumes a helical orientation upon deployment.
  • U.S. Patent No. 5,738,683 discloses a cardiac mapping/ablation catheter that includes an electrode that may be deployed in the shape of a loop.
  • U.S. Patent No. 5,782,879 discloses an endocardial mapping and ablation system in which the catheter includes a deploy able distal extremity, in the form of a cage-like member that includes a plurality of electrodes.
  • the present invention provides a cardiac catheter system for ablating tissue to electrically isolate certain tissue from arrhythmia-inducing foci.
  • the invention is primarily shown and described as a cardiac catheter system for ablating tissue with RF energy, it is understood that the system has other applications and embodiments as well.
  • other types of energy such as microwave, laser, cryogenic, and ultrasonic energy, can be used without departing from the scope of the invention.
  • a cardiac ablation catheter system in one embodiment, includes an elongate, flexible sheath having an internal lumen and an open distal end.
  • An ablating element is disposed within the sheath and is selectively deployable therefrom so as to project from the sheath in a substantially coil-like shape.
  • the deployed ablating element has a geometry forming at least one revolution for generating a circumferential lesion within a vessel, such as a pulmonary vein.
  • the ablating element is oriented in a plane that is substantially orthogonal to the longitudinal axis of the sheath in the deployed position to facilitate the formation of a lesion about the vein inner wall circumference.
  • the catheter system can include a variety of mechanisms for deploying the ablation member from the catheter.
  • the ablation member is released from a distal end of the catheter such that it assumes a predetermined shape.
  • the catheter includes a hatch or port from which the ablation member is selectively deployed.
  • the elongate member includes a distal end affixed to a support member that is extendable from the catheter distal end. By rotating and/or longitudinally displacing the support member, the ablation member can be deployed such it assumes a desired size.
  • the catheter is manipulated through the arterial network until the catheter is located proximate the desired treatment site.
  • the treatment site may be a location within the pulmonary vein or left atrium at or near the pulmonary vein os or in the right ventricular outflow tract, such as at the junction of the right atrium and superior vena cava.
  • the ablating element is then deployed from the catheter such that the coil-like ablating element is generally oriented in a plane orthogonal to the longitudinal axis of the sheath.
  • the deployed ablating element should be in contact with tissue about the circumference of the vein inner wall, such as at the os.
  • the ablation element is then energized to ablate the target tissue to electrically isolate the foci from healthy tissue on the opposite side of the formed lesion.
  • the atria for example, can be electrically isolated from a treated pulmonary vein by creating a circumferential lesion on the inner wall of the left atrium or in the pulmonary vein proximate the os.
  • FIG. 1 is a perspective view of an ablation catheter system in accordance with the present invention
  • FIG. 2 is a side view of a portion of the catheter system of FIG. 1;
  • FIG. 3 is a front view of a portion of the catheter system of FIG. 1;
  • FIG. 4 is a pictorial representation of the orientation of an ablating element in a deployed position and a catheter that forms a part of the catheter system of FIG. 1 ;
  • FIG. 5 is a perspective view of an alternative geometry for an ablating element
  • FIG. 6 is a perspective view of a further embodiment of an ablation catheter system in accordance with the present invention
  • FIG. 7 is a perspective view of another embodiment of an ablation catheter in accordance with the present invention.
  • FIG. 7 A is a pictorial representation of an alternative embodiment of an ablation catheter in accordance with the present invention
  • FIG. 8A is a pictorial representation of a further embodiment of an ablation catheter in accordance with the present invention shown in a first position
  • FIG. 8B is a pictorial representation of the catheter of FIG. 8A shown in a second position
  • FIG. 8C is a pictorial representation of the catheter system of FIG. 8A shown in a a third position.
  • FIG. 9 is a perspective view of another embodiment of an ablation catheter system in accordance with the present invention.
  • FIGS. 1-3 show an ablation catheter system 100 in accordance with the present invention having an ablation element 102 that is deployable from a flexible elongate catheter or sheath 104.
  • the catheter sheath 104 should be semi-rigid and flexible so as to be readily steerable to a desired location in a patient's body, such as proximate the os of a pulmonary vein.
  • catheter delivery systems are well known to those of ordinary skill in the art.
  • the deployed coil-like ablation element 102 has a shape that includes one or more revolutions substantially oriented in a transverse plane 106 (FIG. 4) that is orthogonal to a longitudinal axis 108 of the sheath 104.
  • This geometry facilitates treating tissue about a circumference of a vessel, such as a pulmonary vein.
  • the circumferential region of ablated tissue electrically isolates tissue on opposite sides of the ablated tissue.
  • the atria for example, can be electrically isolated from any arrhythmia-inducing foci within the pulmonary vein.
  • the catheter system 100 includes a tubular inner member 110 for housing the ablation member 102 in the non-deployed position.
  • the inner member 102 be formed from an insulative material to prevent unintended contact with tissue, for example.
  • Exemplary materials for the insulative inner member 110 include Teflon and polyethylene.
  • the elongate ablation element 102 can have a variety of geometries that are effective to form a generally annular lesion about a circumference of a vessel wall. Exemplary geometries include annular shapes having one or more revolutions, crenulated, corrugated, and combinations thereof. It is understood that the term “revolution” should be construed broadly to include configurations of somewhat less than three hundred and sixty degrees. It is further understood that the transverse plane 106 on which the revolutions of the elongate member are located provides a general frame of reference and that the elongate member can vary in distance from the plane as the elongate member forms a revolution.
  • the ablation member 102 has a coil-like appearance that forms approximately one revolution generally oriented in the transverse plane 106 that is substantially orthogonal to a longitudinal axis 108 of the sheath.
  • This configuration is well-suited for contacting a vessel inner wall about its circumference or for contacting the posterior wall of the left atrium to circumscribe the os of a pulmonary vein.
  • the resultant circumferential lesion on the atrial or vessel wall can be effective to isolate electrical impulses from the offending foci from passing to healthy tissue on the opposite side of the lesion.
  • FIG. 5 shows the catheter system 100' including an ablation member 102' having an alternative, crenulated geometry. That is, the ablation member 102' undulates so as to intersect the transverse plane 106' at defined intervals along a revolution. This configuration may inhibit or limit stenosis of the treated vessel proximate the circumferential lesion.
  • the ablation member 102' can be partly surrounded by an insulative coating 112.
  • the ablation member 102 is formed from a conductive elastic or superelastic shape memory material for ablating tissue with RF energy.
  • shape memory materials include nickel-titanium alloys, such as Nitinol, and copper based alloys. It is understood that shape memory materials, in general, can be plastically deformed from a first shape at a relatively low temperature. Upon heating the material to some higher temperature, such as by resistive heating, the material will tend to return to the first shape. Such materials can have so-called one-way and two- way shape memories.
  • the ablation member can be at least partly surrounded by an insulative coating. The insulative coating can be disposed on the ablation member so as to form a plurality of discrete electrodes for ablating tissue at selected locations along the vessel circumference.
  • the ablation element can be deployed from the sheath using a variety of mechanisms that are compatible with steerable catheter systems.
  • Exemplary mechanisms include predetermined shapes for the elongate member, manual deployment mechanisms, and guide-wire based mechanisms.
  • FIG. 6 shows an ablation catheter system 200 having an ablation member 202 with a distal end 204 secured to a bulbous end 206 of a support member 208.
  • the support member 208 is disposed within the sheath 210 and connected to an actuator (not shown) at a proximal end of the catheter.
  • the support member 208 is longitudinally displaced with respect to the sheath such that the bulbous end 206 protrudes from the end 212 of the catheter.
  • the ablation member 202 Upon exiting the sheath 210, the ablation member 202 assumes a predetermined shape that includes about one revolution in a transverse plane 214 orthogonal to the sheath longitudinal axis 216.
  • the ablation member 202 can extend from a retractable support wire 218.
  • the bulbous end 206 of the support member is radiopaque to facilitate determining the ablation member position on an external viewing system, such as an X-ray system.
  • the ablation member 202 can be wound on the support member
  • the support member 208 can be rotated in a predetermined direction such that the ablation member 202 is unwound or released from the support member. The support member 208 can be rotated until the ablation member extends from the support member a desired distance. After ablation, the ablation member 202 can be retracted to the non-deployed state by rotating the support member in the opposite direction.
  • FIG. 7 A shows an alternative embodiment of a catheter system 350 including an ablation member 352 having an exposed proximal portion 354 for ablating tissue and an insulated distal portion 356 for centering the catheter within a pulmonary vein 358.
  • the catheter system 350 is well suited for creating a circumferential lesion on the posterior left atrial wall 360 around the pulmonary vein os 362.
  • FIGS. 8A-C show a manually expandable ablation member 402 that forms a part of a cardiac ablation catheter system 400 in accordance with the present invention.
  • the system 400 includes a guide-wire based catheter 404 with an ablation member 406 that is manually deployable from the catheter.
  • the ablation member 406 is coupled to a semi-rigid support member 408 (FIG. 8C) that can be rotated and/or longitudinally displaced so as to deploy the ablation member 4026.
  • the size of the loop formed by the ablation member 406 can be selected by controlling the amount of rotation/displacement of the support member 408.
  • the leading end of the ablation element can be affixed to the guide wire.
  • the ablating element can be manipulated by rotating the guide wire.
  • FIG. 9 shows a further embodiment of a guide-wire based ablation catheter system 500 having a manually deployable ablation member 502.
  • This system is similar to the system 200 shown in FIG 6 with the addition of a guide wire 504 that can provide additional stability during ablation.
  • the catheter 506 is mounted on the guide wire 504 to facilitate advancement of the catheter into the pulmonary vein.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Surgical Instruments (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Un cathéter d'ablation cardiaque (100) comporte un élément d'ablation du type spirale (102), qui saille en position déployée d'une gaine souple allongée (104). L'élément d'ablation (102), lorsqu'il est déployé, présente au moins une spire orientée dans un plan orthogonal à un axe longitudinal (108) de la gaine. Le système de cathéter (100) convient bien à l'ablation d'une zone circonférentielle de tissu autour d'une veine pulmonaire ou de la paroi postérieure de l'oreillette gauche, à proximité de la cavité de la veine pulmonaire. La zone de tissu traitée isole électriquement l'atrium de la veine pulmonaire.
PCT/US2000/024836 1999-09-15 2000-09-11 Systeme de catheter d'ablation cardiaque spirale Ceased WO2001019270A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00961755A EP1223876A4 (fr) 1999-09-15 2000-09-11 Systeme de catheter d'ablation cardiaque spirale
JP2001522910A JP2003522561A (ja) 1999-09-15 2000-09-11 コイル型切除カテーテルシステム
CA002388823A CA2388823C (fr) 1999-09-15 2000-09-11 Systeme de catheter d'ablation cardiaque spirale

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/396,959 US6607520B2 (en) 1999-09-15 1999-09-15 Coiled ablation catheter system
US09/396,959 1999-09-15
US09/539,056 2000-03-30
US09/539,056 US6632223B1 (en) 2000-03-30 2000-03-30 Pulmonary vein ablation stent and method

Publications (1)

Publication Number Publication Date
WO2001019270A1 true WO2001019270A1 (fr) 2001-03-22

Family

ID=27015709

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2000/024836 Ceased WO2001019270A1 (fr) 1999-09-15 2000-09-11 Systeme de catheter d'ablation cardiaque spirale
PCT/US2000/024835 Ceased WO2001019269A1 (fr) 1999-09-15 2000-09-11 Stent d'ablation de veine pulmonaire et procede de traitement associe

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2000/024835 Ceased WO2001019269A1 (fr) 1999-09-15 2000-09-11 Stent d'ablation de veine pulmonaire et procede de traitement associe

Country Status (4)

Country Link
EP (1) EP1223876A4 (fr)
JP (1) JP2003522561A (fr)
CA (2) CA2638963C (fr)
WO (2) WO2001019270A1 (fr)

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US6890329B2 (en) 1999-06-15 2005-05-10 Cryocath Technologies Inc. Defined deflection structure
WO2007094887A3 (fr) * 2005-12-29 2007-12-13 Boston Scient Scimed Inc Sonde d'ablation à aiguille unique déployable surbaissée
WO2013028993A3 (fr) * 2011-08-24 2013-04-18 Boston Scientific Scimed, Inc. Dispositif et procédés de modulation de nerfs
WO2014152038A3 (fr) * 2013-03-15 2014-12-11 Medtronic Ardian Luxembourg S.A.R.L. Electrode en fil hélicoïdale à pousser
EP2949283A1 (fr) * 2014-05-30 2015-12-02 Biosense Webster (Israel) Ltd. Cathéter doté d'une section distale à boucles côte à côte
EP3146924A1 (fr) * 2015-09-24 2017-03-29 Medidata Sp. z o.o. Cryoapplicateur pour ablation cardiaque chirurgical à invasion minimale
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
US12082917B2 (en) 2018-01-24 2024-09-10 Medtronic Ireland Manufacturing Unlimited Company Systems, devices, and methods for assessing efficacy of renal neuromodulation therapy

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WO2003003948A1 (fr) 2001-07-06 2003-01-16 Tricardia, L.L.C. Dispositifs anti-arythmie et leurs utilisations
DE10152066A1 (de) * 2001-10-25 2003-05-08 Curative Ag Stent
US6656175B2 (en) * 2001-12-11 2003-12-02 Medtronic, Inc. Method and system for treatment of atrial tachyarrhythmias
US6814733B2 (en) 2002-01-31 2004-11-09 Biosense, Inc. Radio frequency pulmonary vein isolation
DE10218426A1 (de) * 2002-04-24 2003-11-06 Biotronik Mess & Therapieg Ablationsvorrichtung für Herzgewebe, insbesondere zur Erzeugung linearer Läsionen zwischen zwei Gefäßmündungen im Herzen
US20040106952A1 (en) * 2002-12-03 2004-06-03 Lafontaine Daniel M. Treating arrhythmias by altering properties of tissue
EP1605866B1 (fr) 2003-03-03 2016-07-06 Syntach AG Implant de bloc electrique
EP1605875A3 (fr) 2003-03-03 2005-12-28 Sinus Rhythm Technologies, Inc. Dispositif de positionnement de blocs electriques et procedes d'utilisation dudit dispositif
WO2005039689A2 (fr) 2003-10-24 2005-05-06 Sinus Rhythm Technologies, Inc. Procedes et dispositifs pour la creation de bloc electrique en des sites specifiques du tissu cardiaque avec ablation de tissu cible
SE526861C2 (sv) 2003-11-17 2005-11-15 Syntach Ag Vävnadslesionsskapande anordning samt en uppsättning av anordningar för behandling av störningar i hjärtrytmregleringssystemet
US9398967B2 (en) 2004-03-02 2016-07-26 Syntach Ag Electrical conduction block implant device
US20050222672A1 (en) * 2004-04-01 2005-10-06 Cappella, Inc. Ostial stent
US8798706B2 (en) * 2008-10-04 2014-08-05 Boston Scientific Scimed, Inc. Loop structures for supporting diagnostic and/or therapeutic elements in contact with tissue
US8712550B2 (en) 2008-12-30 2014-04-29 Biosense Webster, Inc. Catheter with multiple electrode assemblies for use at or near tubular regions of the heart
US10166067B2 (en) * 2009-02-12 2019-01-01 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation catheter and method for electically isolating cardiac tissue

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US5738683A (en) * 1994-07-16 1998-04-14 Osypka; Peter Mapping and ablation catheter
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WO2007094887A3 (fr) * 2005-12-29 2007-12-13 Boston Scient Scimed Inc Sonde d'ablation à aiguille unique déployable surbaissée
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WO2014152038A3 (fr) * 2013-03-15 2014-12-11 Medtronic Ardian Luxembourg S.A.R.L. Electrode en fil hélicoïdale à pousser
US9179974B2 (en) 2013-03-15 2015-11-10 Medtronic Ardian Luxembourg S.A.R.L. Helical push wire electrode
EP4032492A1 (fr) * 2013-03-15 2022-07-27 Medtronic Ardian Luxembourg S.à.r.l. Electrode en fil hélicoïdale à pousser
US10792098B2 (en) 2013-03-15 2020-10-06 Medtronic Ardian Luxembourg S.A.R.L. Helical push wire electrode
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
US9468407B2 (en) 2014-05-30 2016-10-18 Biosense Webster (Israel) Ltd. Catheter with distal section having side-by-side loops
US9788894B2 (en) 2014-05-30 2017-10-17 Biosense Webster (Israel) Ltd. Catheter with distal section having side-by-side loops
US10143518B2 (en) 2014-05-30 2018-12-04 Biosense Webster (Israel) Ltd. Catheter with distal section having side-by-side loops
EP2949283A1 (fr) * 2014-05-30 2015-12-02 Biosense Webster (Israel) Ltd. Cathéter doté d'une section distale à boucles côte à côte
WO2017051367A1 (fr) * 2015-09-24 2017-03-30 Medidata Sp. Z O.O. Cryoapplicateur pour ablation cardiaque chirurgicale minimalement invasive
EP3146924A1 (fr) * 2015-09-24 2017-03-29 Medidata Sp. z o.o. Cryoapplicateur pour ablation cardiaque chirurgical à invasion minimale
US10893898B2 (en) 2015-09-24 2021-01-19 Medidata Sp. Zo.O Cryoapplicator for minimally invasive surgical cardiac ablation
US12082917B2 (en) 2018-01-24 2024-09-10 Medtronic Ireland Manufacturing Unlimited Company Systems, devices, and methods for assessing efficacy of renal neuromodulation therapy

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EP1223876A1 (fr) 2002-07-24
WO2001019269A1 (fr) 2001-03-22
EP1223876A4 (fr) 2003-05-02
JP2003522561A (ja) 2003-07-29
CA2388823C (fr) 2008-11-18
CA2388823A1 (fr) 2001-03-22
CA2638963A1 (fr) 2001-03-22
CA2638963C (fr) 2012-03-20

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