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WO2001009307A3 - SYSTEMATIC SEARCH FOR NITRIC OXIDE SYNTHASE MODULATORS - Google Patents

SYSTEMATIC SEARCH FOR NITRIC OXIDE SYNTHASE MODULATORS Download PDF

Info

Publication number
WO2001009307A3
WO2001009307A3 PCT/GB2000/002926 GB0002926W WO0109307A3 WO 2001009307 A3 WO2001009307 A3 WO 2001009307A3 GB 0002926 W GB0002926 W GB 0002926W WO 0109307 A3 WO0109307 A3 WO 0109307A3
Authority
WO
WIPO (PCT)
Prior art keywords
nitric oxide
oxide synthase
systematic search
synthase modulators
modulators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2000/002926
Other languages
French (fr)
Other versions
WO2001009307A2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9918075.4A external-priority patent/GB9918075D0/en
Priority claimed from GB0016174A external-priority patent/GB0016174D0/en
Application filed by Individual filed Critical Individual
Priority to EP00948183A priority Critical patent/EP1203095A2/en
Priority to AU61746/00A priority patent/AU6174600A/en
Publication of WO2001009307A2 publication Critical patent/WO2001009307A2/en
Publication of WO2001009307A3 publication Critical patent/WO2001009307A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/GB2000/002926 1999-07-30 2000-07-28 Screen for nitric oxide synthase modulators Ceased WO2001009307A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00948183A EP1203095A2 (en) 1999-07-30 2000-07-28 Screen for nitric oxide synthase modulators
AU61746/00A AU6174600A (en) 1999-07-30 2000-07-28 Screen for nitric oxide synthase modulators

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9918075.4 1999-07-30
GBGB9918075.4A GB9918075D0 (en) 1999-07-30 1999-07-30 Screen for nitric oxide synthase modulators
GB0016174A GB0016174D0 (en) 2000-06-30 2000-06-30 Screen for nitric acid synthase modulators
GB0016174.5 2000-06-30

Publications (2)

Publication Number Publication Date
WO2001009307A2 WO2001009307A2 (en) 2001-02-08
WO2001009307A3 true WO2001009307A3 (en) 2001-08-23

Family

ID=26244582

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/002926 Ceased WO2001009307A2 (en) 1999-07-30 2000-07-28 Screen for nitric oxide synthase modulators

Country Status (3)

Country Link
EP (1) EP1203095A2 (en)
AU (1) AU6174600A (en)
WO (1) WO2001009307A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002555A1 (en) * 1996-07-12 1998-01-22 Salerno John C Applications for regulatory region of nos isoforms
US5759836A (en) * 1995-03-27 1998-06-02 Hospital For Joint Diseases Osteoarthritis-associated inducable isoform of nitric oxide synthetase
WO1998026066A1 (en) * 1996-12-09 1998-06-18 Ariad Gene Therapeutics, Inc. Expression of proteins for treating asthma via ligand mediated activation of their encoding genes
WO1999011620A1 (en) * 1997-08-28 1999-03-11 Pfizer Products Inc. Branched alkoxy-subsituted 2-aminopyridines as nos inhibitors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759836A (en) * 1995-03-27 1998-06-02 Hospital For Joint Diseases Osteoarthritis-associated inducable isoform of nitric oxide synthetase
WO1998002555A1 (en) * 1996-07-12 1998-01-22 Salerno John C Applications for regulatory region of nos isoforms
WO1998026066A1 (en) * 1996-12-09 1998-06-18 Ariad Gene Therapeutics, Inc. Expression of proteins for treating asthma via ligand mediated activation of their encoding genes
WO1999011620A1 (en) * 1997-08-28 1999-03-11 Pfizer Products Inc. Branched alkoxy-subsituted 2-aminopyridines as nos inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NO ET AL: "ECDYSONE-INDUCIBLE EXPRESSION IN MAMMALIAN CELLS AND TRANSGENIC MICE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, INDIA. SECTION A, PHYSICAL SCIENCES,IN,NATIONAL ACADEMY OF SCIENCE, ALLAHABAD, vol. 93, 1996, pages 3346 - 3351, XP002136440, ISSN: 0369-8203 *

Also Published As

Publication number Publication date
WO2001009307A2 (en) 2001-02-08
AU6174600A (en) 2001-02-19
EP1203095A2 (en) 2002-05-08

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