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WO2001090659A1 - Device for the production of polymer chips - Google Patents

Device for the production of polymer chips Download PDF

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Publication number
WO2001090659A1
WO2001090659A1 PCT/EP2001/004521 EP0104521W WO0190659A1 WO 2001090659 A1 WO2001090659 A1 WO 2001090659A1 EP 0104521 W EP0104521 W EP 0104521W WO 0190659 A1 WO0190659 A1 WO 0190659A1
Authority
WO
WIPO (PCT)
Prior art keywords
air
air humidification
chamber
humidification chamber
polymer chips
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/004521
Other languages
German (de)
French (fr)
Inventor
Wolfgang Heimberg
Andreas Soubek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MWG Biotech AG
Original Assignee
MWG Biotech AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MWG Biotech AG filed Critical MWG Biotech AG
Priority to AU52268/01A priority Critical patent/AU5226801A/en
Publication of WO2001090659A1 publication Critical patent/WO2001090659A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F6/00—Air-humidification, e.g. cooling by humidification
    • F24F6/02—Air-humidification, e.g. cooling by humidification by evaporation of water in the air
    • F24F6/04—Air-humidification, e.g. cooling by humidification by evaporation of water in the air using stationary unheated wet elements
    • F24F6/043—Air-humidification, e.g. cooling by humidification by evaporation of water in the air using stationary unheated wet elements with self-sucking action, e.g. wicks
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00—Control or safety arrangements
    • F24F11/70—Control systems characterised by their outputs; Constructional details thereof
    • F24F11/72—Control systems characterised by their outputs; Constructional details thereof for controlling the supply of treated air, e.g. its pressure
    • F24F11/74—Control systems characterised by their outputs; Constructional details thereof for controlling the supply of treated air, e.g. its pressure for controlling air flow rate or air velocity
    • F24F11/77—Control systems characterised by their outputs; Constructional details thereof for controlling the supply of treated air, e.g. its pressure for controlling air flow rate or air velocity by controlling the speed of ventilators
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00—Control or safety arrangements
    • F24F11/0008—Control or safety arrangements for air-humidification
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F5/00—Air-conditioning systems or apparatus not covered by F24F1/00 or F24F3/00, e.g. using solar heat or combined with household units such as an oven or water heater
    • F24F5/0042—Air-conditioning systems or apparatus not covered by F24F1/00 or F24F3/00, e.g. using solar heat or combined with household units such as an oven or water heater characterised by the application of thermo-electric units or the Peltier effect
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D22/00—Control of humidity
    • G05D22/02—Control of humidity characterised by the use of electric means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00495—Means for heating or cooling the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00529—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00—Control or safety arrangements
    • F24F11/30—Control or safety arrangements for purposes related to the operation of the system, e.g. for safety or monitoring
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F2110/00—Control inputs relating to air properties
    • F24F2110/20—Humidity

Definitions

  • the present invention relates to a device for producing polymer chips.
  • a device for applying small liquid droplets to a carrier surface is known.
  • This carrier surface is usually a surface of a small glass plate.
  • polymer droplets in particular DNA droplets and RNA droplets, are applied to the glass plates in a regular pattern.
  • the application is referred to as "spotting".
  • Such a device can be used to produce DNA chips.
  • These devices have a closed working chamber, in which a work surface is arranged, on which several glass plates can be arranged. Microtiter plates, which contain the liquids to be applied, are usually found on the work surface.
  • the working chambers are locked to maintain a certain indoor climate so that the liquid droplets are applied safely and do not dry out after application.
  • These devices are usually designed as table devices. Despite the closed Chamber of Labor, it has been shown that
  • WO 99/36760 A1 is incorporated into the present application with reference.
  • DE-44 11 644 C1 describes an air humidification device consisting of a chamber through which the air to be humidified flows and in which there is a ceramic body wetted with water.
  • the ceramic body has a predetermined pore structure, so that there is a large surface on which water can be evaporated to humidify air.
  • DE-92 07 870 U1 shows a further evaporation humidifier which has a filter mat consisting of paper grids. This filter mat is impregnated with water and flows through an air flow generated by a fan 16. Moisture is absorbed in the air as it flows through the filter mat.
  • DE-29 06 607 A1 relates to a device for automatically filling water vapors on radiators in living and working rooms.
  • the water level in the evaporator tank is detected by a sensor and the supply of water is controlled depending on the detected water level.
  • the water supply is controlled by a valve inserted in the supply line.
  • the invention has for its object to provide a device for producing polymer chips, with which the desired air properties, in particular the humidity and / or the temperature, can be kept in predetermined ranges and which allows a more secure manufacture of the polymer chips than the previously known devices ,
  • FIG. 2 shows the air treatment device according to FIG. 1 in a partial sectional view
  • FIG. 3 is a top view of the air treatment device according to FIG. 1 with the cover removed
  • Fig. 4 shows a device for producing polymer chips in perspective
  • FIG 5 shows an air treatment device with a cooling device.
  • FIG. 1 schematically shows an air treatment device 1 in a perspective view.
  • This air treatment device has an air humidification chamber 2 and a control housing 3.
  • the air humidification chamber 2 has a base wall 4 and four circumferentially arranged side walls 5 (FIGS. 1 and 2).
  • the bottom wall 4 is approximately square with an edge length a of 15 to 20 cm.
  • the height b of the side walls is approximately 6 to 10 cm.
  • Ventilation slots 6 are introduced in the side walls 5 and extend from the upper edge region of the side walls 5 to approximately half the height b of the side walls. This means that in the area below the ventilation slots 6, the air humidification chamber 2 forms a watertight container.
  • the air humidification chamber 2 is closed with a cover 7.
  • the cover 7 is a flat plate, the side edges of which are formed so that they engage behind the side walls 5.
  • a circular ventilation opening 8 is made in the middle of the cover 7.
  • a fan 9, which is driven by an electric motor 10, is arranged in the area below this ventilation opening 8.
  • the electric motor 10 is controlled by a control device 11, which is located in the control housing 3.
  • a display 12 and buttons 13 for setting a predetermined humidity range are provided on the control housing 3.
  • a protruding sensor element 14 for measuring the air humidity is arranged on the control housing 3.
  • the air humidification chamber 2 is filled with water, the water level being somewhat lower than the lower edges of the ventilation slots 6.
  • a porous absorbent body 16 which is approximately star-shaped in plan view, is placed in the air humidification chamber 2 (FIG. 3). This absorbent body 16 absorbs the water by capillary forces and forms a moist, large surface.
  • the electric motor 10 is actuated, the fan 9 is rotated such that air is sucked into the air humidification chamber 2 through the ventilation opening 8. The air is propelled along the surface of the water and along the surface of the absorbent body 16 protruding from the water, absorbing moisture. The moist air is discharged through the ventilation slots 6 to the outside.
  • the operation of the fan 9 is controlled by the control device 11 in such a way that the air humidity measured with the sensor element 14 is in a predetermined range. This means that when the measured humidity reaches a lower threshold, the fan is actuated and when the humidity reaches an upper threshold, the fan is switched off.
  • the set humidity is typically in a range from 60% to 70%.
  • this very flat air treatment device is suitable for precisely regulating the air humidity in the working chamber of a device for producing polymer chips.
  • the arrangement according to the invention of the fan 9 at a short distance and approximately parallel to the water level in the air humidification chamber allows this compact and flat design of the air humidification chamber 2.
  • a device for producing polymer chips is shown schematically simplified in a perspective representation in FIG. 4.
  • the device 17 has a base plate 18, four glass side walls 19 and a cover 20 which is essentially supported by four columns 21. Electrical and mechanical control devices are integrated in the cover 20.
  • a worktop is arranged in parallel and at a distance from the base plate 18 and is attached to the columns 21.
  • a robot arm 23 is attached to the cover 20 and has devices for receiving and applying liquids, as are known from WO 99 / 30760A1.
  • the air treatment device 1 is arranged in the area between the base plate 18 and the worktop 22. With this air treatment device 1 can safely drying out of the polymer chips can be avoided and the desired air humidity can be set very precisely.
  • the flat construction of the air treatment device allows the air treatment device to be inserted into existing devices 17 for producing polymer chips. No retrofitting work on the devices 17 is necessary.
  • This air treatment device 1 in turn has an air humidification chamber 2 and a control housing 3, which are identical to the air humidification chamber 2 and the
  • control housing 3 of the embodiment shown in FIGS. 1-3 are formed.
  • a cooling block 26 is attached to the air humidification chamber 2 on the side wall 5 opposite the control housing 3.
  • the cooling block 26 has cooling fins 27 on its surface, which are cooled by means of a Peltier element (not shown). The waste heat from the Peltier elements is removed using a liquid
  • 5 keitsmediums which is preferably water, circulates via two hoses 28 to a heat exchanger 29.
  • the heat exchanger 29 is provided with further cooling fins 30 and has a circulation pump (not shown) for circulating the cooling medium.
  • a temperature control device is also integrated in the housing of the heat exchanger 29, which controls the circulation pump and the Peltier elements.
  • the electrical connection to the Peltier elements is made along one of the tubes 28.
  • the air temperature is measured and the cooling by the cooling block 26 is controlled in accordance with the temperature.
  • the sensor element for measuring the air temperature is preferably arranged as far as possible from the cooling block, so that a
  • the unit consisting of the air humidification chamber 2, the control housing 3 and the cooling block 26 is set in the device 17 for producing polymer chips and the heat exchanger 29 is placed outside this device. orderly.
  • the tubes 28 are led out through corresponding openings in the side walls 19 of the device 17 for producing polymer chips.
  • the air humidity and the temperature of the working chamber of the device 17 for producing polymer chips can thus be set and regulated.
  • the temperature range is usually in the range from 10 ° C. to 20 ° C., which is why only one cooling device is provided, since this temperature is usually below the room temperature of the room in which the device 17 is located. Should higher temperatures be necessary, the cooling block 26 can also be used as a heating block by reversing the polarity of the Peltier elements.
  • This air treatment device 1 can easily be inserted into an existing device 17 for producing polymer chips, without this having to be converted.
  • an air treatment device into the device 17 for producing polymer chips.
  • a cooling block it is expedient to design the cooling block as part of one of the side walls of the device 17 for producing polymer chips, so that the Peltier element with a surface and heat exchanger fins arranged on it points inward into the working chamber and the another surface and heat exchanger fins arranged thereon is arranged facing outward.
  • the pellet element with two sets of heat exchanger fins allows heat to be dissipated from the working chamber to the outside without the provision of an additional cooling circuit.
  • the air humidification chamber can be provided with a fill level sensor and a device for automatically refilling water into the air humidification chamber in accordance with the fill level sensor.
  • water is conveyed into the air humidification chamber by means of a pump from a water storage container, which is substantially larger than the air humidification chamber, by means of a pump.
  • the water reservoir is arranged outside the working chamber of the device for producing polymer chips. It can be of any size and can be refilled at any time, which enables continuous operation of the air treatment device.
  • the air treatment device prefferably be arranged outside the working chamber of the device for producing polymer chips, and for air to be removed from the working chamber to the air treatment device by means of a hose, to be appropriately moistened and / or tempered there, and to the working chamber again via a further hose is fed.

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  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Sustainable Development (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Drying Of Gases (AREA)
  • Air Conditioning Control Device (AREA)

Abstract

The invention relates to a device for the production of polymer chips, comprising an essentially closed working chamber, in which an air humidifier and a sensor element for measuring the humidity (14) of the air are arranged and an electronic controller unit (11) of such a form that said unit controls the air humidifier according to the measured values of air humidity.

Description

Vorrichtung zum Erzeugen von Polvmerchips Device for producing polymer chips

5 Die vorliegende Erfindung betrifft eine Vorrichtung zum Erzeugen von Polymerchips.5 The present invention relates to a device for producing polymer chips.

Aus der WO 99/36760 A1 ist eine Vorrichtung zum Auftragen kleiner Flüssigkeitströpfchen auf eine Trägerfläche bekannt. Diese Trägerfläche ist meistens eine Oberfläche eines kleinen Glasplättchens. Mit dieser Vorrichtung werden Polymertröpf- 0 chen, insbesondere DNA-Tröpfchen und RNA-Tröpfchen, auf die Glasplättchen in einem regelmäßigen Raster aufgebracht. Das Aufbringen wird als „Spotten" bezeichnet.From WO 99/36760 A1 a device for applying small liquid droplets to a carrier surface is known. This carrier surface is usually a surface of a small glass plate. With this device, polymer droplets, in particular DNA droplets and RNA droplets, are applied to the glass plates in a regular pattern. The application is referred to as "spotting".

Mit einer solchen Vorrichtung können DNA-Chips hergestellt werden.Such a device can be used to produce DNA chips.

Diese Vorrichtungen weisen eine geschlossene Arbeitskammer auf, in weicher eine Arbeitsfläche angeordnet ist, auf der mehrere Glasplättchen angeordnet werden können. Auf der Arbeitsfläche finden sich in der Regel Mikrotiterplatten, in welchen die aufzutragenden Flüssigkeiten enthalten sind.These devices have a closed working chamber, in which a work surface is arranged, on which several glass plates can be arranged. Microtiter plates, which contain the liquids to be applied, are usually found on the work surface.

.0.0

Die Arbeitskammern sind abgeschlossen, um ein bestimmtes Raumklima beizubehalten, damit die Flüssigkeitströpfchen sicher aufgetragen und nicht nach dem Auftragen eintrocknen. Diese Vorrichtungen sind in der Regel als Tischvorrichtungen ausgebildet. Trotz der abgeschlossenen Arbeitskammer hat sich gezeigt, dass dasThe working chambers are locked to maintain a certain indoor climate so that the liquid droplets are applied safely and do not dry out after application. These devices are usually designed as table devices. Despite the closed Chamber of Labor, it has been shown that

!5 darin befindliche Raumklima, insbesondere die Luftfeuchtigkeit, oftmals nicht im erforderlichen Bereich liegt, um eine sichere Erzeugung von Polymerchips zu gewährleisten.! 5 The indoor climate, especially the air humidity, is often not in the required range to ensure the safe generation of polymer chips.

Die WO 99/36760 A1 wird in die vorliegende Anmeldung unter Bezugnahme inkorpo- 10 riert.WO 99/36760 A1 is incorporated into the present application with reference.

Die DE-44 11 644 C1 beschreibt eine Luftbefeuchtungsvorrichtung bestehend aus einer von der zu befeuchtenden Luft durchströmten Kammer, in welcher sich ein mit Wasser benetzter Keramikkörper befindet. Der Keramikkörper weist eine vorbe- !5 stimmte Porenstruktur auf, so daß eine große Oberfläche vorliegt, an welcher Wasser zur Befeuchtung von Luft verdunstet werden kann. Aus der DE-92 07 870 U1 geht ein weiterer Verdunstungs-Luftbefeuchter hervor, der eine aus Papiergittern bestehende Filtermatte aufweist. Diese Filtermatte ist mit Wasser getränkt und wird von einer durch einen Ventilator 16 erzeugten Luftströmung durchströmt. Beim Durchströmen der Filtermatte wird in der Luft Feuchtigkeit aufgenommen.DE-44 11 644 C1 describes an air humidification device consisting of a chamber through which the air to be humidified flows and in which there is a ceramic body wetted with water. The ceramic body has a predetermined pore structure, so that there is a large surface on which water can be evaporated to humidify air. DE-92 07 870 U1 shows a further evaporation humidifier which has a filter mat consisting of paper grids. This filter mat is impregnated with water and flows through an air flow generated by a fan 16. Moisture is absorbed in the air as it flows through the filter mat.

Die DE-29 06 607 A1 betrifft eine Vorrichtung zum automatischen Befüllen von Was- serverdunstem an Heizkörpern in Wohn- und Arbeitsräumen. Hierbei wird der Wasserstand im Behälter des Verdunsters über einen Fühler erfaßt und die Zufuhr von Wasser in Abhängigkeit von dem erfaßten Wasserstand gesteuert. Die Steuerung der Wasserzufuhr erfolgt über ein in die Zuführleitung eingefügtes Ventil.DE-29 06 607 A1 relates to a device for automatically filling water vapors on radiators in living and working rooms. Here, the water level in the evaporator tank is detected by a sensor and the supply of water is controlled depending on the detected water level. The water supply is controlled by a valve inserted in the supply line.

Der Erfindung liegt die Aufgabe zugrunde, eine Vorrichtung zum Erzeugen von Polymerchips zu schaffen, mit welcher die gewünschten Lufteigenschaften, insbesondere die Feuchtigkeit und/oder die Temperatur, in vorgegebenen Bereichen gehalten werden kann und die eine sicherere Herstellung der Polymerchips als die bisher bekannten Vorrichtungen erlaubt.The invention has for its object to provide a device for producing polymer chips, with which the desired air properties, in particular the humidity and / or the temperature, can be kept in predetermined ranges and which allows a more secure manufacture of the polymer chips than the previously known devices ,

Die Aufgaben werden durch eine Vorrichtung mit den Merkmalen des Anspruch 1 gelöst. Vorteilhafte Ausgestaltungen der Erfindung sind in den Unteransprüchen angegeben.The objects are achieved by a device with the features of claim 1. Advantageous embodiments of the invention are specified in the subclaims.

Die Erfindung wird im folgenden anhand der Zeichnungen näher erläutert. Diese zeigen in:The invention is explained in more detail below with reference to the drawings. These show in:

Fig. 1 eine Luftbehandlungsvorrichtung in perspektivischer Ansicht,1 shows an air treatment device in a perspective view,

Fig. 2 die Luftbehandlungsvorrichtung nach Fig. 1 in einer Teilschnittdarstellung,2 shows the air treatment device according to FIG. 1 in a partial sectional view,

Fig. 3 die Luftbehandlungsvorrichtung nach Fig. 1 in der Draufsicht mit abgenommenem Deckel, Fig. 4 eine Vorrichtung zum Erzeugen von Polymerchips in perspektivischer3 is a top view of the air treatment device according to FIG. 1 with the cover removed, Fig. 4 shows a device for producing polymer chips in perspective

Darstellung, undRepresentation, and

Fig. 5 eine Luftbehandlungsvorrichtung mit einer Kühleinrichtung.5 shows an air treatment device with a cooling device.

Fig. 1 zeigt schematisch eine Luftbehandlungsvorrichtung 1 in perspektivischer Ansicht. Diese Luftbehandiungsvorrichtung weist eine Luftbefeuchtungskammer 2 und ein Steuergehäuse 3 auf. Die Luftbefeuchtungskammer 2 besitzt eine Bodenwan- düng 4 und vier umlaufend angeordnete Seitenwandungen 5 (Fig. 1 und 2). Die Bodenwandung 4 ist etwa quadratisch mit einer Kantenlänge a von 15 bis 20 cm ausgebildet. Die Höhe b der Seitenwandungen beträgt etwa 6 bis 10 cm. In den Seitenwandungen 5 sind Lüftungsschlitze 6 eingebracht, die sich vom oberen Randbereich der Seitenwandungen 5 bis etwa zur halben Höhe b der Seitenwandungen erstre- cken. Dies bedeutet, dass im Bereich unterhalb der Lüftungsschlitze 6 die Luftbefeuchtungskammer 2 einen wasserdichten Behälter bildet. Nach oben hin ist die Luftbefeuchtungskammer 2 mit einem Deckel 7 abgeschlossen. Der Deckel 7 ist eine flache Platte, dessen Seitenkanten gekragt ausgebildet sind, so dass sie die Seitenwandungen 5 hintergreifen. In der Mitte des Deckels 7 ist eine kreisförmige Belüf- tungsöffnung 8 eingebracht. Im Bereich unterhalb dieser Belüftungsöffnung 8 ist ein Ventilator 9 angeordnet, der von einem Elektromotor 10 angetrieben wird. Der Elektromotor 10 wird von einer Steuereinrichtung 11 , die sich im Steuergehäuse 3 befindet, angesteuert. Am Steuergehäuse 3 sind eine Anzeige 12 und Tasten 13 zum Einstellen eines vorbestimmten Feuchtigkeitsbereiches vorgesehen. Zudem ist am Steuergehäuse 3 ein vorstehendes Sensorelement 14 zum Messen der Luftfeuchtigkeit angeordnet.1 schematically shows an air treatment device 1 in a perspective view. This air treatment device has an air humidification chamber 2 and a control housing 3. The air humidification chamber 2 has a base wall 4 and four circumferentially arranged side walls 5 (FIGS. 1 and 2). The bottom wall 4 is approximately square with an edge length a of 15 to 20 cm. The height b of the side walls is approximately 6 to 10 cm. Ventilation slots 6 are introduced in the side walls 5 and extend from the upper edge region of the side walls 5 to approximately half the height b of the side walls. This means that in the area below the ventilation slots 6, the air humidification chamber 2 forms a watertight container. At the top, the air humidification chamber 2 is closed with a cover 7. The cover 7 is a flat plate, the side edges of which are formed so that they engage behind the side walls 5. A circular ventilation opening 8 is made in the middle of the cover 7. A fan 9, which is driven by an electric motor 10, is arranged in the area below this ventilation opening 8. The electric motor 10 is controlled by a control device 11, which is located in the control housing 3. A display 12 and buttons 13 for setting a predetermined humidity range are provided on the control housing 3. In addition, a protruding sensor element 14 for measuring the air humidity is arranged on the control housing 3.

Im Betrieb wird die Luftbefeuchtungskammer 2 mit Wasser gefüllt, wobei der Wasserspiegel etwas niedriger als die unteren Kanten der Lüftungsschlitze 6 ist. Zudem wird ein poröser, beispielsweise in der Draufsicht etwa sternförmig ausgebildeter Saugkörper 16 in die Luftbefeuchtungskammer 2 eingestellt (Fig. 3). Dieser Saugkörper 16 saugt durch Kapillarkräfte das Wasser auf und bildet eine feuchte großflächige Oberfläche. Beim Betätigen des Elektromotors 10 wird der Ventilator 9 derart gedreht, dass durch die Belüftungsöffnung 8 Luft in die Luftbefeuchtungskammer 2 gesaugt wird. Die Luft wird entlang der Wasseroberfläche und entlang der aus dem Wasser ragenden Oberfläche des Saugkörpers 16 getrieben, wobei sie Feuchtigkeit aufnimmt. Die feuchte Luft wird durch die Lüftungsschlitze 6 hindurch nach außen abgegeben.In operation, the air humidification chamber 2 is filled with water, the water level being somewhat lower than the lower edges of the ventilation slots 6. In addition, a porous absorbent body 16, which is approximately star-shaped in plan view, is placed in the air humidification chamber 2 (FIG. 3). This absorbent body 16 absorbs the water by capillary forces and forms a moist, large surface. When the electric motor 10 is actuated, the fan 9 is rotated such that air is sucked into the air humidification chamber 2 through the ventilation opening 8. The air is propelled along the surface of the water and along the surface of the absorbent body 16 protruding from the water, absorbing moisture. The moist air is discharged through the ventilation slots 6 to the outside.

Der Betrieb des Ventilators 9 wird von der Steuereinrichtung 11 derart gesteuert, dass die mit dem Sensorelement 14 gemessene Luftfeuchtigkeit in einem vorbestimmten Bereich liegt. Das bedeutet, dass wenn die gemessene Luftfeuchtigkeit ei- nen unteren Schwellwert erreicht, der Ventilator betätigt wird, und wenn die Luftfeuchtigkeit einen oberen Schwellwert erreicht, der Ventilator ausgeschaltet wird. Die eingestellte Luftfeuchtigkeit liegt typischerweise in einem Bereich von 60% bis 70%.The operation of the fan 9 is controlled by the control device 11 in such a way that the air humidity measured with the sensor element 14 is in a predetermined range. This means that when the measured humidity reaches a lower threshold, the fan is actuated and when the humidity reaches an upper threshold, the fan is switched off. The set humidity is typically in a range from 60% to 70%.

Es hat sich gezeigt, dass diese, sehr flach ausgebildete Luftbehandlungsvorrichtung zum exakten Regeln der Luftfeuchtigkeit der Arbeitskammer einer Vorrichtung zum Erzeugen von Polymerchips geeignet ist. Die erfindungsgemäße Anordnung des Ventilators 9 mit geringem Abstand und etwa parallel zum Wasserspiegel in der Luftbefeuchtungskammer erlaubt diese kompakte und flache Ausbildung der Luftbefeuchtungskammer 2.It has been shown that this very flat air treatment device is suitable for precisely regulating the air humidity in the working chamber of a device for producing polymer chips. The arrangement according to the invention of the fan 9 at a short distance and approximately parallel to the water level in the air humidification chamber allows this compact and flat design of the air humidification chamber 2.

Eine Vorrichtung zum Erzeugen von Polymerchips ist in Fig. 4 schematisch vereinfacht in perspektivischer Darstellung gezeigt. Die Vorrichtung 17 weist eine Bodenplatte 18, vier aus Glas ausgebildete Seitenwandungen 19 und einen Deckel 20 auf, der im wesentlichen von vier Säulen 21 getragen wird. Im Deckel 20 sind elektrische und mechanische Steuereinrichtungen integriert. Eine Arbeitsplatte ist parallel und mit Abstand zur Bodenplatte 18 angeordnet und ist an den Säulen 21 befestigt. Am Deckel 20 ist ein Roboterarm 23 befestigt, der Einrichtungen zum Aufnehmen und Auftragen von Flüssigkeiten aufweist, wie sie aus der WO 99/30760A1 bekannt sind. Auf der Arbeitsplatte 22 befinden sich Mikrotiterplatten 24 und Aufnahmebereiche 25 zum Aufnehmen von Trägerplättchen, auf welchen die Flüssigkeitstropfen aufzutragen sind.A device for producing polymer chips is shown schematically simplified in a perspective representation in FIG. 4. The device 17 has a base plate 18, four glass side walls 19 and a cover 20 which is essentially supported by four columns 21. Electrical and mechanical control devices are integrated in the cover 20. A worktop is arranged in parallel and at a distance from the base plate 18 and is attached to the columns 21. A robot arm 23 is attached to the cover 20 and has devices for receiving and applying liquids, as are known from WO 99 / 30760A1. On the worktop 22 there are microtiter plates 24 and receiving areas 25 for receiving carrier plates on which the liquid drops are to be applied.

Im Bereich zwischen der Bodenplatte 18 und der Arbeitsplatte 22 ist die Luftbehandlungsvorrichtung 1 angeordnet. Mit dieser Luftbehandlungsvorrichtung 1 kann sicher ein Austrocknen der Polymerchips vermieden werden und die gewünschte Luftfeuchtigkeit kann sehr exakt eingestellt werden. Der flache Aufbau der Luftbehandlungsvorrichtung erlaubt ein Einstellen der Luftbehandlungsvorrichtung in bestehende Vorrichtungen 17 zum Erzeugen von Polymerchips. Es sind keinerlei Umrüstarbeiten an 5 den Vorrichtungen 17 notwendig.The air treatment device 1 is arranged in the area between the base plate 18 and the worktop 22. With this air treatment device 1 can safely drying out of the polymer chips can be avoided and the desired air humidity can be set very precisely. The flat construction of the air treatment device allows the air treatment device to be inserted into existing devices 17 for producing polymer chips. No retrofitting work on the devices 17 is necessary.

Fig. 5 zeigt ein weiteres Ausführungsbeispiel der Luftbehandlungsvorrichtung. Diese Luftbehandlungsvorrichtung 1 weist wiederum eine Luftbefeuchtungskammer 2 und ein Steuergehäuse 3 auf, die identisch zu der Luftbefeuchtungskammer 2 und dem5 shows a further exemplary embodiment of the air treatment device. This air treatment device 1 in turn has an air humidification chamber 2 and a control housing 3, which are identical to the air humidification chamber 2 and the

0 Steuergehäuse 3 das in den Fig. 1-3 gezeigten Ausführungsbeispieles ausgebildet sind. An der Luftbefeuchtungskammer 2 ist an der dem Steuergehäuse 3 gegenüberliegenden Seitenwandung 5 ein Kühlblock 26 angebracht. Der Kühlblock 26 besitzt an seiner Oberfläche Kühlrippen 27, die mittels eines Peltier-Elementes (nicht dargestellt) gekühlt werden. Die Abwärme der Peltier-Elemente wird mittels eines Flüssig-0 control housing 3 of the embodiment shown in FIGS. 1-3 are formed. A cooling block 26 is attached to the air humidification chamber 2 on the side wall 5 opposite the control housing 3. The cooling block 26 has cooling fins 27 on its surface, which are cooled by means of a Peltier element (not shown). The waste heat from the Peltier elements is removed using a liquid

5 keitsmediums, das vorzugsweise Wasser ist, über zwei Schläuche 28 zu einem Wärmetauscher 29 zirkuliert. Der Wärmetauscher 29 ist mit weiteren Kühlrippen 30 versehen und weist eine Umwälzpumpe (nicht dargestellt) zum Zirkulieren des Kühlmediums auf.5 keitsmediums, which is preferably water, circulates via two hoses 28 to a heat exchanger 29. The heat exchanger 29 is provided with further cooling fins 30 and has a circulation pump (not shown) for circulating the cooling medium.

!0 In das Gehäuse des Wärmetauschers 29 ist zudem eine Temperatursteuereinrichtung integriert, die die Umwälzpumpe und die Peltier-Elemente ansteuert. Die elektrische Verbindung zu den Peltier-Elementen ist entlang einem der Schläuche 28 geführt.! 0 A temperature control device is also integrated in the housing of the heat exchanger 29, which controls the circulation pump and the Peltier elements. The electrical connection to the Peltier elements is made along one of the tubes 28.

!5 Mittels eines Sensorelementes (nicht dargestellt), das in den Kühlblock 26 integriert oder an der Luftbefeuchtungskammer 2 oder dem Steuergehäuse 3 angeordnet ist, wird die Lufttemperatur gemessen und nach Maßgabe der Temperatur die Kühlung durch den Kühlblock 26 gesteuert. Vorzugsweise ist das Sensorelement zum Messen der Lufttemperatur möglichst weit vom Kühlblock entfernt angeordnet, damit eine! 5 By means of a sensor element (not shown), which is integrated in the cooling block 26 or arranged on the air humidification chamber 2 or the control housing 3, the air temperature is measured and the cooling by the cooling block 26 is controlled in accordance with the temperature. The sensor element for measuring the air temperature is preferably arranged as far as possible from the cooling block, so that a

;0 möglichst stabile Regelung erzielt wird.; 0 control that is as stable as possible is achieved.

Im Betrieb wird die aus der Luftbefeuchtungskammer 2, dem Steuergehäuse 3 und dem Kühlblock 26 bestehende Einheit in die Vorrichtung 17 zum Erzeugen von Polymerchips eingestellt und der Wärmetauscher 29 außerhalb dieser Vorrichtung an- geordnet. Die Schläuche 28 werden durch entsprechende Öffnungen in den Seitenwandungen 19 der Vorrichtung 17 zum Erzeugen von Polymerchips herausgeführt.In operation, the unit consisting of the air humidification chamber 2, the control housing 3 and the cooling block 26 is set in the device 17 for producing polymer chips and the heat exchanger 29 is placed outside this device. orderly. The tubes 28 are led out through corresponding openings in the side walls 19 of the device 17 for producing polymer chips.

Mit dieser Luftbehandlungsvorrichtung lässt sich somit die Luftfeuchtigkeit und die Temperatur der Arbeitskammer der Vorrichtung 17 zum Erzeugen von Polymerchips einstellen und regeln. Üblicherweise liegt der Temperaturbereich im Bereich von 10°C bis 20°C, weshalb lediglich eine Kühlvorrichtung vorgesehen ist, da diese Temperatur üblicherweise unterhalb der Raumtemperatur des Raumes liegt, in dem sich die Vorrichtung 17 befindet. Sollten höhere Temperaturen notwendig sein, kann durch eine umgepolte Ansteuerung der Peltier-Elemente der Kühlblock 26 auch als Heizblock verwendet werden.With this air treatment device, the air humidity and the temperature of the working chamber of the device 17 for producing polymer chips can thus be set and regulated. The temperature range is usually in the range from 10 ° C. to 20 ° C., which is why only one cooling device is provided, since this temperature is usually below the room temperature of the room in which the device 17 is located. Should higher temperatures be necessary, the cooling block 26 can also be used as a heating block by reversing the polarity of the Peltier elements.

Diese Luftbehandlungsvorrichtung 1 kann einfach in eine bestehende Vorrichtung 17 zum Erzeugen von Polymerchips eingestellt werden, ohne dass diese umgerüstet werden muss.This air treatment device 1 can easily be inserted into an existing device 17 for producing polymer chips, without this having to be converted.

Im Rahmen der Erfindung ist es selbstverständlich auch möglich, eine Luftbehandlungsvorrichtung in die Vorrichtung 17 zum Erzeugen von Polymerchips baulich zu integrieren. Bei einer solchen Ausführungsform mit einem Kühlblock ist es zweckmä- ßig, den Kühlblock als Bestandteil einer der Seitenwandungen der Vorrichtung 17 zum Erzeugen von Polymerchips auszubilden, so dass das Peltier-Element mit einer Fläche und daran angeordneten Wärmetauscherrippen nach innen in die Arbeitskammer weisend und der anderen Fläche und daran angeordneten Wärmetauscherrippen nach außen weisend angeordnet ist. Durch eine derartige Anordnung des Pel- tier-Elementes mit zwei Sätzen von Wärmetauscherrippen kann ohne Vorsehen eines zusätzlichen Kühlkreises Wärme aus der Arbeitskammer nach außen abgeführt werden.Within the scope of the invention it is of course also possible to structurally integrate an air treatment device into the device 17 for producing polymer chips. In such an embodiment with a cooling block, it is expedient to design the cooling block as part of one of the side walls of the device 17 for producing polymer chips, so that the Peltier element with a surface and heat exchanger fins arranged on it points inward into the working chamber and the another surface and heat exchanger fins arranged thereon is arranged facing outward. Such an arrangement of the pellet element with two sets of heat exchanger fins allows heat to be dissipated from the working chamber to the outside without the provision of an additional cooling circuit.

Im Rahmen der Erfindung kann die Luftbefeuchtungskammer mit einem Füllstand- sensor und einer Einrichtung zum automatischen Nachfüllen von Wasser in die Luft- befeuchtungskammer nach Maßgabe des Füllstandsensors versehen sein. Hierbei wird aus einem Wasservorratsbehälter, der wesentlich größer als die Luftbefeuchtungskammer ist, Wasser in der vom Füllstandsensor vorgegebenen Menge mittels einer Pumpe in die Luftbefeuchtungskammer gefördert. Der Wasservorratsbehälter ist außerhalb der Arbeitskammer der Vorrichtung zum Erzeugen von Polymerchips angeordnet. So kann er in beliebiger Größe ausgebildet sein und jederzeit nachgefüllt werden, wodurch ein kontinuierlicher Betrieb der Luftbehandlungsvorrichtung möglich ist.In the context of the invention, the air humidification chamber can be provided with a fill level sensor and a device for automatically refilling water into the air humidification chamber in accordance with the fill level sensor. In this case, water is conveyed into the air humidification chamber by means of a pump from a water storage container, which is substantially larger than the air humidification chamber, by means of a pump. The water reservoir is arranged outside the working chamber of the device for producing polymer chips. It can be of any size and can be refilled at any time, which enables continuous operation of the air treatment device.

Es ist auch möglich, dass die Luftbehandlungsvorrichtung ausserhalb der Arbeitskammer der Vorrichtung zum Erzeugen von Polymerchips angeordnet ist, und dass Luft aus der Arbeitskammer zur Luftbehandlungsvorrichtung mittels eines Schlauches abgeführt, dort entsprechend befeuchtet und/oder temperiert wird, und über einen weiteren Schlauch wieder der Arbeitskammer zugeführt wird. It is also possible for the air treatment device to be arranged outside the working chamber of the device for producing polymer chips, and for air to be removed from the working chamber to the air treatment device by means of a hose, to be appropriately moistened and / or tempered there, and to the working chamber again via a further hose is fed.

BezugszeichenlisteLIST OF REFERENCE NUMBERS

LuftbehandlungsvorrichtungAir treatment device

LuftbefeuchtungskammerLuftbefeuchtungskammer

Steuergehäusecontrol housing

Bodenwandungbottom wall

Seitenwandungsidewall

Lüftungsschlitzevents

Deckelcover

Belüftungsöffnungventilation opening

Ventilatorfan

Elektromotorelectric motor

Steuereinrichtungcontrol device

Anzeigedisplay

TastenKeys

Sensorelementsensor element

Maximaler WasserspiegelMaximum water level

Saugkörpersuction body

Vorrichtung zum Erzeugen von PolymerchipsDevice for producing polymer chips

Bodenplattebaseplate

Seitenwandungensidewalls

Deckelcover

Säulepillar

Arbeitsplattecountertop

Roboterarmrobot arm

Mikrotiterplattemicrotiter plate

Aufnahmebereich für TrägerplättchenHolding area for carrier plates

Kühlblockcooling block

Kühlrippecooling fin

Schlauchtube

Wärmetauscherheat exchangers

Kühlrippe cooling fin

Claims

Schutzansprüche protection claims 1. Vorrichtung zum Erzeugen von Polymerchips mit einer im wesentlichen geschlossenen Arbeitskammer, in der eine Luftbefeuchtungseinrichtung und ein Sensorelement (14) zum Messen der Luftfeuchtigkeit angeordnet sind, und mit einer elektronischen Steuereinrichtung (11), die derart ausgebildet ist, dass sie nach Maßgabe der gemessenen Luftfeuchtigkeit die Luftbefeuchtungseinrichtung ansteuert.1. Device for producing polymer chips with a substantially closed working chamber, in which an air humidification device and a sensor element (14) for measuring the air humidity are arranged, and with an electronic control device (11), which is designed such that it according to the measured humidity controls the humidifier. 2. Vorrichtung nach Anspruch 1 , dadurch gekennzeichnet, dass die Luftbefeuchtungseinrichtung eine Luftbefeuchtungskammer (2) aufweist, die einen wasserdichten Behälter bis zu einem vorbestimmten Niveau bildet und ober- halb dieses vorbestimmten Niveaus Belüftungsöffnungen (6, 8) und eine elektromotorisch angetriebenen Ventilator (9) aufweist.2. Device according to claim 1, characterized in that the air humidification device has an air humidification chamber (2) which forms a watertight container up to a predetermined level and above this predetermined level ventilation openings (6, 8) and an electric motor-driven fan (9 ) having. 3. Vorrichtung nach Anspruch 2, dadurch gekennzeichnet, dass in der Luftbefeuchtungskammer (2) ein poröser, großflächiger Saugkörper (16) angeordnet ist.3. Device according to claim 2, characterized in that a porous, large-area absorbent body (16) is arranged in the air humidification chamber (2). 4. Vorrichtung nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, dass die Höhe b der Luftbefeuchtungsvorrichtung im Bereich von 6 cm bis 10 cm liegt.4. Device according to one of claims 1 to 3, characterized in that the height b of the air humidification device is in the range of 6 cm to 10 cm. 5. Vorrichtung nach einem der Ansprüche 2 bis 4, dadurch gekennzeichnet, dass ein Füllstandsensor in der Luftbefeuchtungskammer (2) und eine Einrichtung zum automatischen Nachfüllen von Wasser in die Luftbefeuchtungskammer (2) nach Maßgabe des Füllstandsensors vorgesehen ist.5. Device according to one of claims 2 to 4, characterized in that a level sensor is provided in the air humidification chamber (2) and a device for automatically refilling water into the air humidification chamber (2) in accordance with the level sensor. 6. Vorrichtung nach einem der Ansprüche 1 bis 5, gekennzeichnet durch eine Kühleinrichtung und einem Temperatursensorelement zum Erfassen der Temperatur und zum Ansteuern der Kühleinrichtung nach Maßgabe des gemessenen Temperaturwertes.6. Device according to one of claims 1 to 5, characterized by a cooling device and a temperature sensor element for detecting the temperature and for controlling the cooling device in accordance with the measured temperature value. 1010 7. Vorrichtung nach Anspruch 6, dadurch gekennzeichnet, dass die Kühleinrichtung ein Peltier-Element aufweist.7. The device according to claim 6, characterized in that the cooling device has a Peltier element. [5 8. Vorrichtung nach Anspruch 7, dadurch gekennzeichnet, dass das Peltierelement in eine der Seitenwandungen der Arbeitskammer derart integriert ist, dass das Peltier-Element mit einer Fläche und daran angeordneten Wärmetauscherrippen nach innen in die Arbeitskammer weisend und der anderen Fläche .0 und daran angeordneten Wärmetauscherrippen nach außen weisend angeordnet ist. 8. The device according to claim 7, characterized in that the Peltier element is integrated into one of the side walls of the working chamber in such a way that the Peltier element with one surface and heat exchanger fins arranged thereon pointing inwards into the working chamber and the other surface .0 and heat exchanger fins arranged thereon is arranged facing outward.
PCT/EP2001/004521 2000-05-24 2001-04-20 Device for the production of polymer chips Ceased WO2001090659A1 (en)

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WO1998000676A1 (en) * 1996-06-28 1998-01-08 Intelligent Enclosures Corporation Environmentally enhanced enclosure for managing cmp contamination
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FR2783041A1 (en) * 1998-09-08 2000-03-10 Ventilateurs A E I B Temperature regulation system for local areas or rooms especially wine cellars

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