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WO2001090115A3 - Haplotypes du gene cdk4 - Google Patents

Haplotypes du gene cdk4 Download PDF

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Publication number
WO2001090115A3
WO2001090115A3 PCT/US2001/016350 US0116350W WO0190115A3 WO 2001090115 A3 WO2001090115 A3 WO 2001090115A3 US 0116350 W US0116350 W US 0116350W WO 0190115 A3 WO0190115 A3 WO 0190115A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
cdk4
gene
disclosed
cdk4 gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/016350
Other languages
English (en)
Other versions
WO2001090115A2 (fr
Inventor
Amy E Duda
Amir Kazemi
Beena Koshy
Elizabeth Ann Sausker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001274874A priority Critical patent/AU2001274874A8/xx
Priority to AU2001274874A priority patent/AU2001274874A1/en
Priority to PCT/US2001/016350 priority patent/WO2001090115A2/fr
Publication of WO2001090115A2 publication Critical patent/WO2001090115A2/fr
Anticipated expiration legal-status Critical
Publication of WO2001090115A3 publication Critical patent/WO2001090115A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des nouveaux variants génétiques du gène de la kinase 4 dépendante des cyclines (CDK4). Elle concerne également divers génotypes, haplotypes et paires d'haplotypes qui existent dans la population totale des Etats-Unis d'Amérique, et concernent ce gène CDK4, de même que des compositions et procédés d'haplotypage et/ou de génotypage du gène CDK4, chez un individu. Elle concerne enfin des polynucléotides définis par la séquence des haplotypes de l'invention.
PCT/US2001/016350 2000-05-19 2001-05-18 Haplotypes du gene cdk4 Ceased WO2001090115A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001274874A AU2001274874A8 (en) 2001-05-18 2001-05-18 Haplotypes of the cdk4 gene
AU2001274874A AU2001274874A1 (en) 2000-05-19 2001-05-18 Haplotypes of the cdk4 gene
PCT/US2001/016350 WO2001090115A2 (fr) 2000-05-19 2001-05-18 Haplotypes du gene cdk4

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20586700P 2000-05-19 2000-05-19
US60/205,867 2000-05-19
PCT/US2001/016350 WO2001090115A2 (fr) 2000-05-19 2001-05-18 Haplotypes du gene cdk4

Publications (2)

Publication Number Publication Date
WO2001090115A2 WO2001090115A2 (fr) 2001-11-29
WO2001090115A3 true WO2001090115A3 (fr) 2003-08-14

Family

ID=27736709

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016350 Ceased WO2001090115A2 (fr) 2000-05-19 2001-05-18 Haplotypes du gene cdk4

Country Status (1)

Country Link
WO (1) WO2001090115A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714329A (en) * 1995-11-29 1998-02-03 Sequana Theraputics, Inc. Methods for the diagnosis of a genetic predisposition to cancer associated with variant CDK4 allele

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714329A (en) * 1995-11-29 1998-02-03 Sequana Theraputics, Inc. Methods for the diagnosis of a genetic predisposition to cancer associated with variant CDK4 allele

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 5 June 1996 (1996-06-05), ZUO ET AL., XP002197856, accession no. NCBI Database accession no. (U37022) *

Also Published As

Publication number Publication date
WO2001090115A2 (fr) 2001-11-29

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