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WO2001079430A3 - A novel polypeptide - human serine protease 9 and the polynucleotide encoding said polypeptide - Google Patents

A novel polypeptide - human serine protease 9 and the polynucleotide encoding said polypeptide Download PDF

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Publication number
WO2001079430A3
WO2001079430A3 PCT/CN2001/000396 CN0100396W WO0179430A3 WO 2001079430 A3 WO2001079430 A3 WO 2001079430A3 CN 0100396 W CN0100396 W CN 0100396W WO 0179430 A3 WO0179430 A3 WO 0179430A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
serine protease
human serine
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2001/000396
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001079430A2 (en
Inventor
Yumin Mao
Yi Xie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Biowindow Gene Development Inc
Original Assignee
Shanghai Biowindow Gene Development Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Development Inc filed Critical Shanghai Biowindow Gene Development Inc
Priority to AU58150/01A priority Critical patent/AU5815001A/en
Publication of WO2001079430A2 publication Critical patent/WO2001079430A2/en
Publication of WO2001079430A3 publication Critical patent/WO2001079430A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention disclosed a new kind of human serine protease 9 andthe polynucleotide encoding said polypeptide and a process for producing the polypeptide by recombinant methods. It also disclosedthe method of applying the polypeptide for the treatment of various kinds of diseases, such as cancer, hemopathy, HIV infection, immune diseases and inflammation. The antagonist of the polypeptide and therapeutic use of the same is also disclosed. In addition,it refers to the use of polynucleotide encoding said human serine protease 9.
PCT/CN2001/000396 2000-03-24 2001-03-23 A novel polypeptide - human serine protease 9 and the polynucleotide encoding said polypeptide Ceased WO2001079430A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU58150/01A AU5815001A (en) 2000-03-24 2001-03-23 A novel polypeptide, a human serine protease 9 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN00115094A CN1315555A (en) 2000-03-24 2000-03-24 Polypeptide-human serine proteinase 9 and polynucleotide for coding it
CN00115094.4 2000-03-24

Publications (2)

Publication Number Publication Date
WO2001079430A2 WO2001079430A2 (en) 2001-10-25
WO2001079430A3 true WO2001079430A3 (en) 2002-02-21

Family

ID=4584563

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000396 Ceased WO2001079430A2 (en) 2000-03-24 2001-03-23 A novel polypeptide - human serine protease 9 and the polynucleotide encoding said polypeptide

Country Status (3)

Country Link
CN (1) CN1315555A (en)
AU (1) AU5815001A (en)
WO (1) WO2001079430A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0887414A2 (en) * 1997-06-09 1998-12-30 Smithkline Beecham Plc Human serine proteases HGBAB90
WO1999040183A1 (en) * 1998-02-06 1999-08-12 Human Genome Sciences, Inc. Human serine protease and serpin polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0887414A2 (en) * 1997-06-09 1998-12-30 Smithkline Beecham Plc Human serine proteases HGBAB90
WO1999040183A1 (en) * 1998-02-06 1999-08-12 Human Genome Sciences, Inc. Human serine protease and serpin polypeptides

Also Published As

Publication number Publication date
AU5815001A (en) 2001-10-30
WO2001079430A2 (en) 2001-10-25
CN1315555A (en) 2001-10-03

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