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WO2001079427A3 - A novel polypeptide, a human ion channel 9 for chlorine and the polynucleotide encoding the polypeptide - Google Patents

A novel polypeptide, a human ion channel 9 for chlorine and the polynucleotide encoding the polypeptide Download PDF

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Publication number
WO2001079427A3
WO2001079427A3 PCT/CN2001/000376 CN0100376W WO0179427A3 WO 2001079427 A3 WO2001079427 A3 WO 2001079427A3 CN 0100376 W CN0100376 W CN 0100376W WO 0179427 A3 WO0179427 A3 WO 0179427A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
chlorine
polynucleotide encoding
ion channel
discloses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2001/000376
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001079427A2 (en
Inventor
Yumin Mao
Yi Xie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Biowindow Gene Development Inc
Original Assignee
Shanghai Biowindow Gene Development Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Development Inc filed Critical Shanghai Biowindow Gene Development Inc
Priority to AU56055/01A priority Critical patent/AU5605501A/en
Publication of WO2001079427A2 publication Critical patent/WO2001079427A2/en
Publication of WO2001079427A3 publication Critical patent/WO2001079427A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention discloses a novel polypeptide, a human ion channel 9 for chlorine, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as paramyatonia, malignant tumor, hemopathy, development disorders, HIV infection, immunological disease, and various inflammation, etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the novel human ion channel 9 for chlorine.
PCT/CN2001/000376 2000-03-22 2001-03-19 A novel polypeptide, a human ion channel 9 for chlorine and the polynucleotide encoding the polypeptide Ceased WO2001079427A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU56055/01A AU5605501A (en) 2000-03-22 2001-03-19 A novel polypeptide, a human ion channel 9 for chlorine and the polynucleotide encoding the polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN00115062.6 2000-03-22
CN00115062A CN1314411A (en) 2000-03-22 2000-03-22 New polypeptide-human chlorine ion path protein 9 and polynucleotide for coding such polypeptide

Publications (2)

Publication Number Publication Date
WO2001079427A2 WO2001079427A2 (en) 2001-10-25
WO2001079427A3 true WO2001079427A3 (en) 2002-01-24

Family

ID=4584533

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000376 Ceased WO2001079427A2 (en) 2000-03-22 2001-03-19 A novel polypeptide, a human ion channel 9 for chlorine and the polynucleotide encoding the polypeptide

Country Status (3)

Country Link
CN (1) CN1314411A (en)
AU (1) AU5605501A (en)
WO (1) WO2001079427A2 (en)

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRANDT S. AND JENTSCH T.J.: "CLC-6 and CLC-7 are two novel broadly expressed members of the CLC chloride channel family", FEBS LETT., vol. 377, no. 1, 1995, pages 15 - 20 *
CLAVERIE J.M. AND MAKALOWSKI W.: "Alu alert", NATURE, vol. 371, no. 6500, 1994, pages 752 *
LAMB F.S. ET AL.: "Expression of CLCN voltage-gated chloride channel genes in human blood vessels", J. MOL. CELL. CARDIOL., vol. 31, no. 3, 1999, pages 657 - 666 *
THIEMANN A. ET AL.: "A chloride channel widely expressed in epithelial and non-epithelial cells", NATURE, vol. 356, no. 6364, 1992, pages 57 - 60 *

Also Published As

Publication number Publication date
WO2001079427A2 (en) 2001-10-25
AU5605501A (en) 2001-10-30
CN1314411A (en) 2001-09-26

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