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WO2001079277A3 - Pilus immunogene presentant des peptides etrangers, sa production et ses utilisations - Google Patents

Pilus immunogene presentant des peptides etrangers, sa production et ses utilisations Download PDF

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Publication number
WO2001079277A3
WO2001079277A3 PCT/US2001/011918 US0111918W WO0179277A3 WO 2001079277 A3 WO2001079277 A3 WO 2001079277A3 US 0111918 W US0111918 W US 0111918W WO 0179277 A3 WO0179277 A3 WO 0179277A3
Authority
WO
WIPO (PCT)
Prior art keywords
pili
immunogenic
production
foreign peptides
presenting foreign
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/011918
Other languages
English (en)
Other versions
WO2001079277A2 (fr
Inventor
Kenneth Denich
M Alexander Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU2001251569A priority Critical patent/AU2001251569A1/en
Publication of WO2001079277A2 publication Critical patent/WO2001079277A2/fr
Publication of WO2001079277A3 publication Critical patent/WO2001079277A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention porte sur un procédé de production de pilus et de vaccins le contenant utilisant des bactéries exprimant au moins un peptide immunogène dans la région PapA qui normalement ne contient pas un tel peptide.
PCT/US2001/011918 2000-04-12 2001-04-12 Pilus immunogene presentant des peptides etrangers, sa production et ses utilisations Ceased WO2001079277A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001251569A AU2001251569A1 (en) 2000-04-12 2001-04-12 Immunogenic pili presenting foreign peptides, their production and use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19649100P 2000-04-12 2000-04-12
US60/196,491 2000-04-12

Publications (2)

Publication Number Publication Date
WO2001079277A2 WO2001079277A2 (fr) 2001-10-25
WO2001079277A3 true WO2001079277A3 (fr) 2002-05-23

Family

ID=22725613

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011918 Ceased WO2001079277A2 (fr) 2000-04-12 2001-04-12 Pilus immunogene presentant des peptides etrangers, sa production et ses utilisations

Country Status (4)

Country Link
US (1) US20020142008A1 (fr)
AR (1) AR028332A1 (fr)
AU (1) AU2001251569A1 (fr)
WO (1) WO2001079277A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2303315A1 (fr) * 2008-05-22 2011-04-06 Ramot at Tel Aviv University Ltd. Procédé de traitement de maladie caractérisée par une plaque
WO2024086846A1 (fr) * 2022-10-21 2024-04-25 University Of Florida Research Foundation, Incorporated Procédés et compositions pour immuniser contre campylobactor hepaticus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0161095A2 (fr) * 1984-04-30 1985-11-13 The Board Of Trustees Of The Leland Stanford Junior University Vaccin contre les infections urinaires
EP0170496A2 (fr) * 1984-07-30 1986-02-05 The Board Of Trustees Of The Leland Stanford Junior University Vaccin contre les infections des voies urinaires

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0161095A2 (fr) * 1984-04-30 1985-11-13 The Board Of Trustees Of The Leland Stanford Junior University Vaccin contre les infections urinaires
US4736017A (en) * 1984-04-30 1988-04-05 The Board Of Trustees Of The Leland Stanford Junior University Chemically defined vaccine against urinary infections
EP0170496A2 (fr) * 1984-07-30 1986-02-05 The Board Of Trustees Of The Leland Stanford Junior University Vaccin contre les infections des voies urinaires
US4740585A (en) * 1984-07-30 1988-04-26 The Board Of Trustees Of The Leland Stanford Junior University Synthetic vaccine against urinary infections

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BAGA M ET AL: "BIOGENESIS OF ESCHERICHIA-COLI PAP PILI PAPH A MINOR PILIN SUBUNIT INVOLVED IN CELL ANCHORING AND LENGTH MODULATION", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 49, no. 2, 1987, pages 241 - 252, XP002183578, ISSN: 0092-8674 *
DENICH K ET AL: "DNA SEQUENCES OF THREE PAPA GENES FROM UROPATHOGENIC ESCHERICHIA-COLI STRAINS EVIDENCE OF STRUCTURAL AND SEROLOGICAL CONSERVATION", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 59, no. 11, November 1991 (1991-11-01), pages 3849 - 3858, XP002183579, ISSN: 0019-9567 *
PECHA B ET AL: "GAL-GAL PILI VACCINES PREVENT PYELONEPHRITIS BY PILIATED ESCHERICHIA COLI IN A MURINE MODEL SINGLE-COMPONENT GAL-GAL PILI VACCINES PREVENT PYELONEPHRITIS BY HOMOLOGOUS AND HETEROLOGOUS PILIATED E. COLI STRAINS", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 83, no. 6, 1989, pages 2102 - 2108, XP001041491, ISSN: 0021-9738 *
STEIDLER L ET AL: "PAP PILI AS A VECTOR SYSTEM FOR SURFACE EXPOSITION OF AN IMMUNOGLOBULIN G-BINDING DOMAIN OF PROTEIN A OF STAPHYLOCOCCUS AUREUS IN ESCHERICHIA COLI", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 175, no. 23, 1 December 1993 (1993-12-01), pages 7639 - 7643, XP000612669, ISSN: 0021-9193 *

Also Published As

Publication number Publication date
WO2001079277A2 (fr) 2001-10-25
US20020142008A1 (en) 2002-10-03
AU2001251569A1 (en) 2001-10-30
AR028332A1 (es) 2003-05-07

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