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WO2001077127A3 - Haplotypes du gene apoc4 - Google Patents

Haplotypes du gene apoc4 Download PDF

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Publication number
WO2001077127A3
WO2001077127A3 PCT/US2001/011715 US0111715W WO0177127A3 WO 2001077127 A3 WO2001077127 A3 WO 2001077127A3 US 0111715 W US0111715 W US 0111715W WO 0177127 A3 WO0177127 A3 WO 0177127A3
Authority
WO
WIPO (PCT)
Prior art keywords
apoc4
gene
haplotypes
disclosed
polymorphisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/011715
Other languages
English (en)
Other versions
WO2001077127A2 (fr
Inventor
Julie Y Choi
Stephanie E Kliem
Beena Koshy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cogenics Inc
Original Assignee
Genaissance Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals Inc filed Critical Genaissance Pharmaceuticals Inc
Priority to AU2001253344A priority Critical patent/AU2001253344A1/en
Publication of WO2001077127A2 publication Critical patent/WO2001077127A2/fr
Publication of WO2001077127A3 publication Critical patent/WO2001077127A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne de nouveaux polymorphismes mononucléotidiques dans le gène humain apolipoprotéine C-IV (APOC4). Elle traite en outre de divers génotypes, haplotypes et paires d'haplotype pour le gène APOC4 qui existent dans la population, ainsi que de compositions et de procédés d'haplotypage et/ou de génotypage du gène APOC4 chez un individu. Elle concerne enfin des polynucléotides qui contiennent au moins un de ces polymorphismes APOC4.
PCT/US2001/011715 2000-04-11 2001-04-10 Haplotypes du gene apoc4 Ceased WO2001077127A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001253344A AU2001253344A1 (en) 2000-04-11 2001-04-10 Haplotypes of the apoc4 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19582500P 2000-04-11 2000-04-11
US60/195,825 2000-04-11

Publications (2)

Publication Number Publication Date
WO2001077127A2 WO2001077127A2 (fr) 2001-10-18
WO2001077127A3 true WO2001077127A3 (fr) 2002-03-14

Family

ID=22722971

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011715 Ceased WO2001077127A2 (fr) 2000-04-11 2001-04-10 Haplotypes du gene apoc4

Country Status (2)

Country Link
AU (1) AU2001253344A1 (fr)
WO (1) WO2001077127A2 (fr)

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALLAN ET AL.: "Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-1 and CII gene locus", GENOMICS, vol. 28, 1995, pages 291 - 300, XP002949160 *
DATABASE SNP [online] NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION, NATIONAL LIBRARY OF MEDICINE, NIH (BERHESDA, MD, USA); September 2000 (2000-09-01), XP002949163, accession no. NCBI *
DATABASE SNP [online] NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION, NATIONAL LIBRARY OF MEDICINE, NIH (BETHESDA, MD, USA); June 1999 (1999-06-01), XP002949161, accession no. NCBI *
GRAAF ET AL.: "Familial chylomicronemia caused by a novel type of mutation in the APOE-CI-CIV-CII gene cluster encompassing both the APOCII gene and the first APOCIV gene mutation: APOCII-CIV", BIOCHEM. AND BIOPHYS. RES. COMMUNICATIONS, vol. 273, 2000, pages 1084 - 1087, XP002949164 *
KAMBOH ET AL.: "DNA sequence variation in human apolipoprotein C4 gene and its effect on plasma lipis profile", ATHEROSCLEROSIS, vol. 152, September 2000 (2000-09-01), pages 193 - 201, XP002949162 *

Also Published As

Publication number Publication date
AU2001253344A1 (en) 2001-10-23
WO2001077127A2 (fr) 2001-10-18

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