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WO2001076553A3 - Method and device for enhanced transdermal drug delivery - Google Patents

Method and device for enhanced transdermal drug delivery Download PDF

Info

Publication number
WO2001076553A3
WO2001076553A3 PCT/US2001/011120 US0111120W WO0176553A3 WO 2001076553 A3 WO2001076553 A3 WO 2001076553A3 US 0111120 W US0111120 W US 0111120W WO 0176553 A3 WO0176553 A3 WO 0176553A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
biological membrane
polysaccharide
permeability
drug delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/011120
Other languages
French (fr)
Other versions
WO2001076553A2 (en
Inventor
Samir S Mitragotri
Tuan A Elstrom
Scott C Kellogg
Joseph Kost
Linda Custer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sontra Medical Inc
Original Assignee
Sontra Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sontra Medical Inc filed Critical Sontra Medical Inc
Priority to AU2001251349A priority Critical patent/AU2001251349A1/en
Publication of WO2001076553A2 publication Critical patent/WO2001076553A2/en
Publication of WO2001076553A3 publication Critical patent/WO2001076553A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method and device for enhanced transdermal drug delivery are disclosed. According to one embodiment of the present invention, the method includes the steps of (1) identifying an area of biological membrane: (2) contacting at least one high-permeability polysaccharide with the identified area of biological membrane; (3) contacting at least one drug with the identified area of biological membrane; and (4) transporting the at least one drug into or through the identified area of biological membrane. According to another embodiment of the present invention, a method for the enhanced transport of a drug into or through a biological membrane includes the steps of (1) preparing a complex of the drug with a high-permeability polysaccharide; and (2) transporting the complex into or through the biological membrane. According to another embodiment of the present invention, a device for enhanced drug delivery includes at least one high-permeability polysaccharide and at least one drug. The device may also include a contact layer that contacts a biological membrane and a medium layer containing the at least one high-permeability polysaccharide and the at least one drug .
PCT/US2001/011120 2000-04-06 2001-04-06 Method and device for enhanced transdermal drug delivery Ceased WO2001076553A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001251349A AU2001251349A1 (en) 2000-04-06 2001-04-06 Method and device for enhanced transdermal drug delivery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19504100P 2000-04-06 2000-04-06
US60/195,041 2000-04-06

Publications (2)

Publication Number Publication Date
WO2001076553A2 WO2001076553A2 (en) 2001-10-18
WO2001076553A3 true WO2001076553A3 (en) 2002-01-24

Family

ID=22719844

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011120 Ceased WO2001076553A2 (en) 2000-04-06 2001-04-06 Method and device for enhanced transdermal drug delivery

Country Status (2)

Country Link
AU (1) AU2001251349A1 (en)
WO (1) WO2001076553A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110025770A (en) * 2019-04-20 2019-07-19 长春生物制品研究所有限责任公司 A kind of stable recombinant human interferon ointment and its production method

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR042815A1 (en) * 2002-12-26 2005-07-06 Alza Corp ACTIVE AGENT SUPPLY DEVICE THAT HAS COMPOUND MEMBERS
AU2015274237B2 (en) * 2014-06-11 2019-11-14 International Scientific Pty Ltd Device and method to treat or prevent joint degeneration
WO2020185053A2 (en) * 2019-03-14 2020-09-17 주식회사 에스엔비아 Microneedle band having improved activity for promoting growth of fingernails and toenails
KR102404662B1 (en) * 2019-03-14 2022-06-02 주식회사 에스엔비아 A nail-growth promoting dissolvable microneedle band
DE102020200423A1 (en) * 2020-01-15 2021-07-15 Beiersdorf Aktiengesellschaft Method for the introduction of active substances into the skin

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5423739A (en) * 1990-03-30 1995-06-13 Alza Corporation Device and method for iontophoretic drug delivery
WO1995028144A1 (en) * 1994-04-13 1995-10-26 Ciba-Geigy Ag Temporally controlled drug delivery systems
US5470582A (en) * 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
WO1998029134A2 (en) * 1996-12-31 1998-07-09 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
WO1999044637A1 (en) * 1998-03-06 1999-09-10 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
EP1060741A1 (en) * 1999-06-14 2000-12-20 Epic Therapeutics, Inc. Sustained release microspheres

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5423739A (en) * 1990-03-30 1995-06-13 Alza Corporation Device and method for iontophoretic drug delivery
US5470582A (en) * 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
WO1995028144A1 (en) * 1994-04-13 1995-10-26 Ciba-Geigy Ag Temporally controlled drug delivery systems
WO1998029134A2 (en) * 1996-12-31 1998-07-09 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
WO1999044637A1 (en) * 1998-03-06 1999-09-10 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
EP1060741A1 (en) * 1999-06-14 2000-12-20 Epic Therapeutics, Inc. Sustained release microspheres

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110025770A (en) * 2019-04-20 2019-07-19 长春生物制品研究所有限责任公司 A kind of stable recombinant human interferon ointment and its production method

Also Published As

Publication number Publication date
WO2001076553A2 (en) 2001-10-18
AU2001251349A1 (en) 2001-10-23

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