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WO2001076373A1 - Composition vegetale d'agent repulsif des moustiques - Google Patents

Composition vegetale d'agent repulsif des moustiques Download PDF

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Publication number
WO2001076373A1
WO2001076373A1 PCT/IN2000/000043 IN0000043W WO0176373A1 WO 2001076373 A1 WO2001076373 A1 WO 2001076373A1 IN 0000043 W IN0000043 W IN 0000043W WO 0176373 A1 WO0176373 A1 WO 0176373A1
Authority
WO
WIPO (PCT)
Prior art keywords
powder
oil
formulation
pyrethrum
bark
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2000/000043
Other languages
English (en)
Inventor
Dinesh Kumar
Yogendra Nath Shukla
Shikha Tiwari
Ravi Prakash Bansal
Sushil Kumar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research CSIR
Original Assignee
Council of Scientific and Industrial Research CSIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research CSIR filed Critical Council of Scientific and Industrial Research CSIR
Priority to AU2000258440A priority Critical patent/AU2000258440A1/en
Priority to PCT/IN2000/000043 priority patent/WO2001076373A1/fr
Priority to CNB008014256A priority patent/CN1158927C/zh
Priority to MYPI20011171 priority patent/MY129017A/en
Publication of WO2001076373A1 publication Critical patent/WO2001076373A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/06Coniferophyta [gymnosperms], e.g. cypress
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/12Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/20Fabaceae or Leguminosae [Pea or Legume family], e.g. pea, lentil, soybean, clover, acacia, honey locust, derris or millettia
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/24Lauraceae [Laurel family], e.g. laurel, avocado, sassafras, cinnamon or camphor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Definitions

  • the present invention relates to a formulation useful as herbal mosquito repellent incense stick.
  • the formulation for the manufacturing of the herbal mosquito repellent incense stick has replaced synthetic compound (allethrin) based traditional mosquito repellents i.e. mats, coils and sprays through herbal mosquito repellent agarbatti, prepared by using natural essential oil of Tagetes minuta (Tyagi et al., 1997 International pest control 39 (6) 184-185) and powder of the pyrethrum flowers (Howard, 1911 U.S. Der. Agr. farmers' Bull. 444 1-15, Nagasawawa et al, 1951, Botyu-Kagaku 16 176-181). Natural repellent based on pyrethrum have been approved and included in WHO Data Sheet on Pesticides under No. 11, 1975 [clause 1.5] in the public health programme.
  • the use of chemical toxicants or mosquito repellents to control mosquito has proved to be one of the most controversial and emotional subjects in recent years.
  • mosquito repellents and insecticides have caused severe environmental pollution and potential health hazards.
  • Introduction of new more toxic and rapidly disseminating mosquito repellents/pesticides into environment has necessitated accurate identification of their potential hazards to human health.
  • Many of them are extremely toxic to mammals/and or other non-target organisms.
  • the extent of hazard depends on the amount of residue and its toxicity.
  • Mosquitoes are known to transmit many diseases such as malaria, dengue, yellow fever, filariasis and Japanese encephalitis.
  • Approximately 40 million people in India suffer from mosquito born diseases annually.
  • the mounting concern in recent years about the use of chemicals to control insect/pest have led to the restrictions and in many cases to complete or partial ban on the use of synthetic insecticides.
  • the insecticidally active constituents of pyrethrum extract are esters, formed by - a combination of two acids, chrysanthemic acid and pyrethric acid and three alcohols, pyrethrolone, cinerolone, and jasmololone.
  • the esters of chrysanthemic acid are called pyrethrin I and pyrthrin II fraction. These compound together account for the kill and knockdown properties of insects.
  • Chrysanthemum cinerariaefolium (Pyrethrum) provides an excellent example of natural combination of materials that is very difficult to reproduce chemically.
  • insecticidal activity in fresh pyrethrum flowers is not diminished by drying at temperature upto 80°C (Godin et al. 1965 J. Sci., Food Agric. 16, 186-191).
  • Alletrin has insecticidal powers and acute toxicity generally comparable to the natural pyrethrins (Negherbon, 1959, "Hand Book of Toxicology” vol. HI).
  • a popular mosquito repellent called Tortoise brand Mosquito coil claim the use of Chrysanthemum cinerariaefolium (pyrethrum flower), as a insecticide.
  • Citrolonellol and citronellal from citronella oil have been found effective oil constituents against mosquito (Travis et al 1946 J. Econ. Ent 42 686).
  • mosquito repellents mainly in the form of mats, coils and liquid sprays are available in the market, but all of them contain synthetic compounds eg. allethrin which causes tremendous health hazards.
  • the market is flooded with the so called herbal mosquito repellent incense sticks but they also have several negative points; firstly they are not herbal as claimed and secondly their burning time is 1.5 to 2 hours only.
  • the incense sticks have no aroma because of the use of bamboo sticks, wood charcoal, sandal wood dust and Jigat- a binding agent when dipped in following solution for aroma and repellency effect.
  • Dimethyl phthalate causes irritation in the tender areas of the skin and eyes.
  • Spray (i) Usually sprays contain synthetic compounds causing health hazards.
  • the main object of the present invention is to develop a formulation useful as herbal mosquito repellent, which obviates the drawbacks in the present mosquito repellents.
  • Another object is to provide a formulation comprising an effective amount of essential oils extracted from aromatic plants together with binding material -Litsea glutinosa (Maida lakri), filling material- Acacia nilotica (babul) bark powder, cyperus rotundus powder and oil obtained from cedrus deodera used for enchancing the repellency.
  • Still another objective of the present invention is to provide a formulation which contains natural essential oil of Tagetes minuta and Chrysanthemum cinerariaefolium (pyrethrum powder) as insect repellents.
  • Yet another object is to provide a mosquito repellent formulation which is safe, biodegradable and has very low mammalian toxicity.
  • One more object of the invention is to provide a formulation useful as a mosquito repellent that is capable of burning for a longer period and thereby having increased efficiency in controlling mosquitoes.
  • Yet another object of the invention is to provide a formulation having 1 kg of maida lakri, 250 g of babul bark powder, 250 g of nagarmotha powder, 100 g of pyrethrum flower powder, 50 g of cedarwood oil and 25 g of Tagetes minuta oil were mixed thoroughly and incense sticks prepared manually with the help of bamboo splints.
  • Still another object of the invention is to provide a method of producing a formulation useful as herbal mosquito repellent, said method comprising mixing an effective amount of the essential oil of Tagetes minuta, Chrysanthemum cinerariaefolium (Pyrethrum powder) and cyperus rotundus powder together with binders and fillers.
  • the present invention provides a herbal formulation and a method of producing the formulation which is useful as a herbal mosquito repellent, said formulation comprising an effective amount of essential oils of cyperus rotundus powder, Chrysanthemum cinerariaefolium (pyrethrum flower), cedarwood oil and Tagetes minuta optionally together with binders and fillers such as Litsea glutinosa, Acacia nilotica.
  • the invention provides a novel formulation useful as herbal mosquito repellent, said formulation comprising an effective amount of the essential oil of Tagetes minuta, Chrysanthemum cinerariaefolium (Pyrethrum powder) and Cedrus deodara (ceder) cyperus rotundus powder together with binders and fillers in the ratio of about 0.20-3.0, 0.5-15, 2.0-3.0, 2.0-3.0, 0.1-1 and 8-10 respectively.
  • the invention provides a novel formulation useful as herbal mosquito repellent, said formulation comprising an effective amount of the essential oil of Tagetes minuta, Cedrus deodera (cedar), Chrysanthemum cinerariaefolium (Pyrethrum) powder and cyperus rotundus powder together with binders and fillers in the preferred ratio of about 0.25:1:2.5:2.5:0.5:10.
  • the Chrysanthemum cinerariaefolium (pyrethrum powder) is obtained from the flowers of the plant Chrysanthemum cinerariaefolium (Pyrethrum).
  • the essential oils are obtained from natural sources such as cedar tree (Cedrus deodara) and the plant Tagetes minuta.
  • the binders in the formulation comprise powder obtained from Litsea glutinosa.
  • the fillers in the formulation comprises powder obtained from the bark o ⁇ Acacia nilotica .
  • the powder of the bark of Litsea glutinosa, Acacia nilotica, cyperus rotundus powder, Chrysanthemum cinerariaefolium (pyrethrum flower), cedarwood (Cedrus deodara) oil and Tagetes minuta oil is in the ratio of about 10:2.50:2.50: 1 :0.50:0.25, respectively.
  • Yet another embodiment of the invention provides a method of producing a formulation useful as herbal mosquito repellent, said method comprising mixing an effective amount of the essential oil of Tagetes minuta, Chrysanthemum cinerariaefolium (Pyrethrum powder) and cyperus rotundus powder together with binders and fillers.
  • the binder powder is obtained from the stems and stem barks of Litsea glutinosa
  • the incense stick manufactured out of the present composition is called "Agarbatti”.
  • the formulation of the present invention may be made in various physical forms such as mosquito repellent coils, sticks, solutions, emulsions etc. as are known in the art.
  • the essential ingredients of the formulation namely the essential oil of Tagetes minuta, cedar, Chrysanthemum cinerariaefolium (Pyrethrum powder) and powder of plant parts oi Cyperus rotundus are mixed with binders and fillers and the like as mentioned above to increase the efficiency of the formulation.
  • Perfumery oils may also be added to the formulation.
  • the amounts of the respective ingredients of the formulation herein mentioned are only exemplary and appropriate amount of the respective ingredients will vary and may be readily determined by a person skilled in the art at the time of making the formulation in its different physical forms.
  • the ratio of the amounts in the formulation of the present invention is not critical and vary widely. The best results would of course be obtained employing the said essential oils with the binders in the proportion aforementioned. Further, the said formulation is found to be effective against several insects specifically mosquitoes.
  • the invention also provides a method for the preparation of a formulation useful as an insect repellent, said method comprising the steps of mixing the essential oils obtained from Tagetes minuta, cedar and cyperus rotundas powder, Chrysanthemum cinerariaefolium (Pyrethrum powder) with conventional binders and fillers in the presence of water.
  • the criteria for a good repellent against mosquito depends on effective protection under all climatic conditions for a long duration and it should be free from all kinds of health hazards such as toxicity and irritation when burning inside a room. Also it should be of low cost, eco-friendly and safe with pleasant odour.
  • Novelty of invention lies in preparation of synergistic herbal mosquito repellent composition wherein addition of Tagetis minuta oil, Cyperus rotundus powder and cedrus deodera oil to the pyrethrum flower power provide the desire novel effect.
  • Example 5 is found to be most suitable as it obviates the drawbacks of Examples 1-4.
  • the Applicants have observed that when only pyrethrum powder is used in the formulation, the insect-repelling capacity of the formulation is moderate. Similarly, when pyrethrum or tagetes minuta oil were not used in the formulation, no repellent effects were observed. Also, when they tagetes minuta oil along with Chrysanthemum cinerariaefolium (pyrethrum) flower were used in the formulation.
  • Incense stick prepared by this combination showed less repellency and burning time was nearly 1.5-2 hours only.
  • Incense stick prepared by this method showed burning period of nearly 3 hrs but gave some respiratory irritation problem due to the presence of more pyrethrum.
  • the incense stick had some burning problem due to more ratio of maida lakri in comparison to filler material.
  • Example 4
  • Incense stick prepared by this combination gave initially some manufacturing problems due to less elasticity and also they burnt less than 2 hours only.
  • Cyperus rotundus ('Nagarmotha powder) 10-20g 4. Chrysanthemum cinerariaefolium (Pyrethrum flower powder) 4-6g
  • Cedrus deodera (Cedar wood oil) 2-5g
  • the formulation is most safe, eco-friendly, easy in use and has maximum repellency power against mosquito.
  • Mosquito repellent herbal incense stick can be used at any place either in villages or in open areas as it does not require any electricity.
  • This technology can generate more employment in rural areas specially for woman in cottage industry.
  • Mosquito repellent herbal incense stick can be prepared in the living houses because it does not require any heavy infrastructure and investment as compared to coils and mats. osquito repellent incense stick prepared by this formulation burns nearly 4.5 hours to 5.0 hours with and after effect of 3 hours.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Botany (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne une formulation à base végétale, utilisée comme agent répulsif des moustiques, caractérisée en ce qu'elle comprend une quantité efficace d'huile essentielle de Tagetes minuta, cedar, Chrysanthemum cinerariaefolium (Pyrethrum en poudre) et de cyperus rotundus, en poudre, conjointement avec des liants et des charges dans le rapport d'environ, respectivement, 0,20-3,0, 0,5-15, 2,0-3,0, 2,0-3,0, 0,1-1 et 8-10.
PCT/IN2000/000043 2000-03-31 2000-03-31 Composition vegetale d'agent repulsif des moustiques Ceased WO2001076373A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2000258440A AU2000258440A1 (en) 2000-03-31 2000-03-31 A herbal mosquito repellent composition
PCT/IN2000/000043 WO2001076373A1 (fr) 2000-03-31 2000-03-31 Composition vegetale d'agent repulsif des moustiques
CNB008014256A CN1158927C (zh) 2000-03-31 2000-03-31 用作草药驱蚊剂焚香杆的制剂
MYPI20011171 MY129017A (en) 2000-03-31 2001-03-14 "a herbal mosquito repellent compositioon and a process for preparing the same"

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2000/000043 WO2001076373A1 (fr) 2000-03-31 2000-03-31 Composition vegetale d'agent repulsif des moustiques

Publications (1)

Publication Number Publication Date
WO2001076373A1 true WO2001076373A1 (fr) 2001-10-18

Family

ID=11076243

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2000/000043 Ceased WO2001076373A1 (fr) 2000-03-31 2000-03-31 Composition vegetale d'agent repulsif des moustiques

Country Status (4)

Country Link
CN (1) CN1158927C (fr)
AU (1) AU2000258440A1 (fr)
MY (1) MY129017A (fr)
WO (1) WO2001076373A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107980818A (zh) * 2017-12-27 2018-05-04 高宗保 除虫菊盘香及其制作方法
WO2022165229A1 (fr) * 2021-01-29 2022-08-04 University Of Florida Research Foundation, Incorporated Mélanges synergétiques comprenant du pyrèthre permettant la toxicité et la répulsion des arthropodes

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105767020A (zh) * 2014-12-19 2016-07-20 余进和 一种固体驱蚊组合物
CN107691505A (zh) * 2017-12-06 2018-02-16 防城港市蓝瀚达科技有限公司 一种复方植物环保蚊香的制作方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04308510A (ja) * 1991-04-05 1992-10-30 Earth Chem Corp Ltd 害虫攪乱剤
JPH04321613A (ja) * 1991-04-19 1992-11-11 Yuukou Yakuhin Kogyo Kk 害虫忌避剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04308510A (ja) * 1991-04-05 1992-10-30 Earth Chem Corp Ltd 害虫攪乱剤
JPH04321613A (ja) * 1991-04-19 1992-11-11 Yuukou Yakuhin Kogyo Kk 害虫忌避剤

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; F.W.MOSHA ET AL.: "BIOLOGICAL EFICACY OF NEW FORMULATIONS OF MOSQUITO COILS AND A CRITICAL REVIEW OF TEST METHODS", XP002153658, retrieved from EPOQUE accession no. PREV198988129125 *
DATABASE CAB [online] CAB INTERNATIONAL, WALLINGFORD, OXON, GB; B.K.TYAGI ET AL.: "Evaluation of repellency effect of Tagetes minuta (Family: Compositae) against the vector mosquitoes Anopheles stephensi Liston, Culex quinquefasciatus Say and Aedes aegipti (L.)", XP002153659, retrieved from STN-INTERNATIONAL accession no. 1998:28189 CABA *
DATABASE WPI Section Ch Week 199250, Derwent World Patents Index; Class C05, AN 1992-411544, XP002153660 *
DATABASE WPI Section Ch Week 199252, Derwent World Patents Index; Class C05, AN 1992-427144, XP002153661 *
INTERNATIONAL PEST CONTROL, vol. 39, no. 6, 1997, pages 184 - 185 *
PYRETHRUM POST, vol. 17, 1989, pages 47 - 51 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107980818A (zh) * 2017-12-27 2018-05-04 高宗保 除虫菊盘香及其制作方法
WO2022165229A1 (fr) * 2021-01-29 2022-08-04 University Of Florida Research Foundation, Incorporated Mélanges synergétiques comprenant du pyrèthre permettant la toxicité et la répulsion des arthropodes

Also Published As

Publication number Publication date
MY129017A (en) 2007-03-30
CN1349384A (zh) 2002-05-15
CN1158927C (zh) 2004-07-28
AU2000258440A1 (en) 2001-10-23

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