WO2001074998A3 - Nouveau polypeptide, proteine humaine de regulation 10 de la serine proteinase, et polynucleotide codant pour ce polypeptide - Google Patents
Nouveau polypeptide, proteine humaine de regulation 10 de la serine proteinase, et polynucleotide codant pour ce polypeptide Download PDFInfo
- Publication number
- WO2001074998A3 WO2001074998A3 PCT/CN2001/000240 CN0100240W WO0174998A3 WO 2001074998 A3 WO2001074998 A3 WO 2001074998A3 CN 0100240 W CN0100240 W CN 0100240W WO 0174998 A3 WO0174998 A3 WO 0174998A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hydrolytic enzyme
- polynucleotide encoding
- protein
- enzyme regulatory
- polypeptide
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004190 Enzymes Human genes 0.000 title abstract 3
- 108090000790 Enzymes Proteins 0.000 title abstract 3
- 102000003839 Human Proteins Human genes 0.000 title abstract 3
- 108090000144 Human Proteins Proteins 0.000 title abstract 3
- 102000034356 gene-regulatory proteins Human genes 0.000 title abstract 3
- 108091006104 gene-regulatory proteins Proteins 0.000 title abstract 3
- 230000003301 hydrolyzing effect Effects 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
L'invention concerne un nouveau polypeptide, une protéine humaine de régulation 10 de la sérine protéinase, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la protéine humaine de régulation 10 de la sérine protéinase.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU46296/01A AU4629601A (en) | 2000-03-10 | 2001-02-26 | A novel polypeptide, human regulation protein 10 of the proteinase serine and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00111980 CN1313312A (zh) | 2000-03-10 | 2000-03-10 | 一种新的多肽——人蛋白水解酶调节蛋白10和编码这种多肽的多核苷酸 |
| CN00111980.X | 2000-03-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001074998A2 WO2001074998A2 (fr) | 2001-10-11 |
| WO2001074998A3 true WO2001074998A3 (fr) | 2002-06-06 |
Family
ID=4581876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000240 WO2001074998A2 (fr) | 2000-03-10 | 2001-02-26 | Nouveau polypeptide, proteine humaine de regulation 10 de la serine proteinase, et polynucleotide codant pour ce polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1313312A (fr) |
| AU (1) | AU4629601A (fr) |
| WO (1) | WO2001074998A2 (fr) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250414A (en) * | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
-
2000
- 2000-03-10 CN CN 00111980 patent/CN1313312A/zh active Pending
-
2001
- 2001-02-26 AU AU46296/01A patent/AU4629601A/en not_active Abandoned
- 2001-02-26 WO PCT/CN2001/000240 patent/WO2001074998A2/fr active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250414A (en) * | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4629601A (en) | 2001-10-15 |
| WO2001074998A2 (fr) | 2001-10-11 |
| CN1313312A (zh) | 2001-09-19 |
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