[go: up one dir, main page]

WO2001073135A3 - Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome - Google Patents

Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome Download PDF

Info

Publication number
WO2001073135A3
WO2001073135A3 PCT/US2001/009856 US0109856W WO0173135A3 WO 2001073135 A3 WO2001073135 A3 WO 2001073135A3 US 0109856 W US0109856 W US 0109856W WO 0173135 A3 WO0173135 A3 WO 0173135A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene region
staging
targeting
approaches
viral genome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/009856
Other languages
French (fr)
Other versions
WO2001073135A2 (en
Inventor
Janet I Cord
Eugen Molodysky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biosearch International Pty Ltd
Original Assignee
Biosearch International Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosearch International Pty Ltd filed Critical Biosearch International Pty Ltd
Priority to AU2001249526A priority Critical patent/AU2001249526A1/en
Publication of WO2001073135A2 publication Critical patent/WO2001073135A2/en
Anticipated expiration legal-status Critical
Publication of WO2001073135A3 publication Critical patent/WO2001073135A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The L1/E1 gene region of the HPV virus may be deleted during integration into the genome of the host cell, but the E6/E7 gene region is always retained. There is a need to detect HPV infection and cervical cancer in way that provides information about the stage of infection so that the proper treatment can be undertaken.
PCT/US2001/009856 2000-03-28 2001-03-27 Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome Ceased WO2001073135A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001249526A AU2001249526A1 (en) 2000-03-28 2001-03-27 Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19267300P 2000-03-28 2000-03-28
US60/192,673 2000-03-28

Publications (2)

Publication Number Publication Date
WO2001073135A2 WO2001073135A2 (en) 2001-10-04
WO2001073135A3 true WO2001073135A3 (en) 2003-01-16

Family

ID=22710596

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/009856 Ceased WO2001073135A2 (en) 2000-03-28 2001-03-27 Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome

Country Status (3)

Country Link
US (1) US20020132227A1 (en)
AU (1) AU2001249526A1 (en)
WO (1) WO2001073135A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0306723A (en) * 2002-01-07 2004-12-21 Norchip As In vitro methods for selecting human subjects to assess their risk of developing cervical carcinoma, and for selecting human subjects for the presence of integrated hpv or a modified episomal hpv genome, in vitro method for identifying human subjects presenting abnormal cell changes in the cervix, and kit for use in detecting mpna transcripts of hpv l1 and e6 genes
ITMO20040126A1 (en) * 2004-05-21 2004-08-21 Bioanalisi Ct Sud S N C Di Per SYSTEM FOR THE RESEARCH AND IDENTIFICATION OF PATHOGENIC AGENTS
EP2184368A1 (en) 2008-11-07 2010-05-12 DKFZ Deutsches Krebsforschungszentrum Diagnostic transcript and splice patterns of HPV16 in different cervical lesions
WO2016049559A1 (en) * 2014-09-25 2016-03-31 Thuraiayah Vinayagamoorthy Diagnostic and prognostic methods for viruses and associated diseases and conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447839A (en) * 1988-09-09 1995-09-05 Hoffmann-La Roche Inc. Detection of human papillomavirus by the polymerase chain reaction
WO1999029890A2 (en) * 1997-12-12 1999-06-17 Digene Corporation Assessment of human papilloma virus-related disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447839A (en) * 1988-09-09 1995-09-05 Hoffmann-La Roche Inc. Detection of human papillomavirus by the polymerase chain reaction
WO1999029890A2 (en) * 1997-12-12 1999-06-17 Digene Corporation Assessment of human papilloma virus-related disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KARLSEN F. ET AL.,: "use of multiple pcr primer sets for optimal detection of human papillomavirus", J. CLINIC. MICORBIOLOGY, vol. 34, no. 9, September 1996 (1996-09-01), pages 2095 - 2100, XP002210544 *

Also Published As

Publication number Publication date
US20020132227A1 (en) 2002-09-19
AU2001249526A1 (en) 2001-10-08
WO2001073135A2 (en) 2001-10-04

Similar Documents

Publication Publication Date Title
WO2005049845A3 (en) Oncolytic herpes simplex virus encoding a heterologous nitroreductase
WO2005014806A3 (en) Conserved hbv and hcv sequences useful for gene silencing
WO2001017551A3 (en) Combined vaccine compositions
NO20054889D0 (en) Optimized expression of HPV 31 LI in fermentation
MY139500A (en) Optimized expression of hpv 58 l1 in yeast
AR039005A1 (en) VIRAL ANTIGENS
Zhao et al. A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein
WO1994021807A3 (en) Defective mutant non-retroviral virus (e.g. hsv) as vaccine
WO2000053729A3 (en) Viral particles which are released after the infection with the human cytomegalovirus and the use of said particles as a vaccine
IL178140A (en) Optimized expression of hpv 52 l1 gene in yeast for preparing a vaccine for treatment or prevention of hpv-associated cervical cancer
BR0014172A (en) Composition
CN101435002A (en) Method for detecting human papilloma virus genotype
AU2002337083A1 (en) Vaccinia virus mva-e3l-knockout-mutants and use thereof
MXPA03000061A (en) Manipulation of negative stranded rna viruses by rearrangement of their genes and uses thereof.
WO2002087614A3 (en) Multivalent vaccine comprising an hiv antigen and an hsv antigen and/or an hpv antigen
WO2003015708A3 (en) Composition and method for treating hiv infection
WO2001073135A3 (en) Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome
EA200300215A1 (en) VACCINATION AGAINST HERPES VIRUSES ASSOCIATED WITH ECONOMIC CELLS
Hoppe‐Seyler et al. Emerging topics in human tumor virology
EP1427443A4 (en) VACCINE USING VIRUS VIRUS-ADJUSTED PAPILLOMA VIRUS PROTEINS
NZ516725A (en) Use of modified HPV as a carrier for vaccine against cancer or viral infection of human papillomavirus
DE69924262D1 (en) METHOD FOR THE PRODUCTION OF YEAST-EXPRESSED HPV TYPS 6 AND 16 KAPSID PROTEINS
CN117568530A (en) A kit for rapid visual typing of human papillomavirus
WO2002004595A3 (en) Production of chimeric human papillomavirus
WO2002055542A3 (en) Hpv-specific peptides, which block the binding of hpv to the host cell

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP