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WO2001070187A1 - CREME DE JOUR A FAIBLE pH ET A TENEUR ELEVEE EN ACIDE GRAS - Google Patents

CREME DE JOUR A FAIBLE pH ET A TENEUR ELEVEE EN ACIDE GRAS Download PDF

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Publication number
WO2001070187A1
WO2001070187A1 PCT/EP2001/002343 EP0102343W WO0170187A1 WO 2001070187 A1 WO2001070187 A1 WO 2001070187A1 EP 0102343 W EP0102343 W EP 0102343W WO 0170187 A1 WO0170187 A1 WO 0170187A1
Authority
WO
WIPO (PCT)
Prior art keywords
acid
fatty acid
composition
alpha
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/002343
Other languages
English (en)
Inventor
Dwiwahyu Haryo Suryo
Sandyarani Noerlan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hindustan Unilever Ltd
Unilever NV
Original Assignee
Hindustan Lever Ltd
Unilever NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hindustan Lever Ltd, Unilever NV filed Critical Hindustan Lever Ltd
Priority to AU2001256179A priority Critical patent/AU2001256179A1/en
Publication of WO2001070187A1 publication Critical patent/WO2001070187A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof

Definitions

  • the present invention relates to a cosmetic vanishing cream with enhanced skin benefit properties.
  • Vanishing creams are popular around the world because they spread easily on the skin giving a thin, semi-matte film which seems to disappear or "vanish” . They are also used to counteract shine which may arise from overactive sebaceous glan ⁇ s. Moreover, these creams counteract skin dryness to alleviate flaking, cracking and roughness.
  • the creams are formulated with high levels of stearic acid suspended in water by an emulsifying agent.
  • the emulsifying agent is a potassium or sodium soap formed by the in si tu reaction of caustic potash or other alkali on a portion of the stearic acid. Consequently, the formulations have a pH above 7, and usually substantially above, because of the presence of alkali.
  • Humectants, such as glycerin, are normally also present in vanishing creams.
  • vanishing cream formulations be adapted to incorporate skin benefit agents.
  • WO 99/37280 (Bartolone et al . ) discloses vanishing creams which are formulated to include alkali or alkaline earth metal salts of alpha-hydroxy carboxylic acids m order to achieve skin lightening properties.
  • the disclosure describes the new products as having pH above 5. Care was taken in this prior art not to incorporate acid versions of the alpha-hydroxy carboxylic acids into the formulation.
  • the beneficial properties of these skin benefit agents have not been realized in such formulations and, thus, it was clear that further work was necessary in order to enhance the performance of vanishing creams.
  • the present invention aims to provide a vanishing cream having a relatively high level of stearic acid and a skin benefit agent which can enhance the performance of the formulation.
  • the present invention also aims to provide a vanishing cream with high levels of stearic acid and skin benefit agents, wherein the cream improves moistu ⁇ zation, enhanced removal of facial oils, reduction in irritation and generally provides an overall smoother, softer skin.
  • a cosmetic composition comprising:
  • composition from 5 to 50° by weight of a C 12 -C 20 fatty acid; (11) from 0.01 to 15° by weight of an acidic skin benefit agent; and wherein the composition has a pH from 1 to less than 5.
  • cosmetic vanishing creams which are formulated to have a pH of less than 5, can stably deliver acidic skin benefit agents thereby resulting in compositions which are effective at reducing, or at least minimizing facial pimple formations.
  • Vanishing creams of the present invention which have a high fatty acid content (over 5% of, for example stearic acid) retain the traditional consumer benefits of such products, even at low pH, namely good moisturization without greasiness/oiliness, ease of absorption, cool sensation and matte finish.
  • Addition of the acidic skin benefit agents results in improvements in the areas of rough/flaky skin, enhancement of skin cell renewal and reduction of pimples.
  • a first essential component of vanishing cream compositions of the present invention is a C ⁇ 2 -C 2 o fatty acid, preferably, stearic acid.
  • the fatty acid will be present in amounts ranging from 5 to 50%, preferably from 7 to 40%, more preferably from 10 to 25%, optimally from 12 to 20% by weight of the composition.
  • a second component of vanishing cream compositions of the present invention is an acidic skin benefit agent, such as alpha- and beta-hydroxycarboxylic acids.
  • a suitable beta- hydroxycarboxylic acid is salicylic acid.
  • the alpha-hydroxy carboxylic acids are represented by formula I having the structure :
  • R and R may be the same or different and are selected from H, F, Cl, Br, alkyl, aralkyl or aryl groups which may be saturated or unsaturated, lsomenc or nonisome ⁇ c, straight or branched chain, having 1 to 25 carbon atoms, or in a cyclic form having 5 or 6 ring members.
  • R and R may be substituted with an OH, CHO, COOH or alkoxy group having 1 to 9 carbon atoms.
  • the alpha-hydroxy acid exists as a free acid, and includes stereoisomers, and D, L, and DL forms thereof when R and R 1 are not identical.
  • 2-hydroxyethano ⁇ c acid (glycolic acid) ; 2-hydroxypropano ⁇ c acid (lactic acid); 2-methyl 2-hydroxypropano ⁇ c acid (methyllactic acid) ; 2-hydroxybutano ⁇ c acid; 2- hydroxypentanoic acid; 2-hydroxyhexano ⁇ c acid; 2- hydroxyheptanoic acid; 2-hydroxyoctano ⁇ c acid; 2- hydroxynonanoic acid; 2-hydroxydecano ⁇ c acid; 2- hydroxyundecanoic acid; 2-hydroxydodecano ⁇ c ac ⁇ d(alpha- hydroxylauric acid) ; 2-hydroxytetradecano ⁇ c acid (alpha- hydroxymy ⁇ stic acid) ; 2-hydroxyhexadecano ⁇ c acid (alpha- hydroxypaimitic acid); 2-hydroxyoctadecano ⁇ c acid (alpha- hydroxystearic acid) ; 2-hydroxye ⁇ cosano ⁇ c acid (alpha- hydroxyarachidonic acid) ; 2-phenyl 2-hydroxy
  • the most preferred alpha-hydroxy carboxylic acids are glycolic acid, lactic acid or 2-hydroxyoctano ⁇ c acid, and mixture thereof.
  • the alpha-hydroxy alkanoic acids may be present in amounts ranging from about 0.1 to about 10%, preferably between about 0.2 and 4%, optimally between about 0.4 and 1% by weight of the composition.
  • a mixture of both a beta-hydroxy carboxylic acid and an alpha-hydroxy carboxylic acid there will be present a mixture of both a beta-hydroxy carboxylic acid and an alpha-hydroxy carboxylic acid.
  • the optimum combination is a mixture of salicylic acid and glycolic acid in a relative weight ratio from about 20:1 to about 1:20, preferably from about 10:1 to 1:1, optimally from about 3:1 to about 2:1.
  • compositions of the present invention may also include a variety of anti-irritancy agents, particularly to counteract irritancy caused by the acidic skin benefit agents.
  • Suitable anti-irritancy agents include gluconolactone, borage seed oil, wild borage, dextran, alpha-bisabolol (extracted from chamomille) , azulene (extracted from yarrow) , resveratrol, petroselenic acid and combinations thereof. Each of these can be present at levels ranging from about 0.0001 to about 5%, preferably from about 0.001 to about 1%, optimally from about 0.01 to about 0.5% by weight of the composition.
  • Herbal extracts may also be included as components of the composition and are particularly effective for controlling the level of sebum/oil.
  • Suitable extracts include dill, horseradish, oats, neem, beet, broccoli, tea, pumpkin, soybean, barley, walnut, flax, ginseng, poppy, avocado, pea, sesame, dandelion, wheat, nettle, cashew, pineapple, apple, asparagus, Brazil nut, chickpea, grapefruit, orange, cucumber, buckwheat, strawberry, gmko, tomato, blueberry, cowpea or grape extracts.
  • Suitable herbal extracts include ivy horse chestnut, centella asiatica, rosmarinic acid, se ⁇ coside, ruscogenm, escin, escolm, betulinic acid, catechm and derivatives thereof. These may be present in amounts ranging from about 0.00001 to about 2%, preferably between about 0.01 and about 0.5% by weight of the composition.
  • Anti-microbial agents may also be useful m compositions of the present invention.
  • the anti-microbial agents are selected from triclosan, t ⁇ carbanilide, tea tree oil, farnesol, farnesol acetate, hexachlorophene, C 4 -C 20 quaternary ammonium salts such as benzalconium chloride and a variety of zinc or aluminum salts.
  • the zinc or aluminum salts are compounds such as zinc pyridmethione, zinc sulphate, zinc chloride, zinc phenolsulphonate, aluminum chloride, aluminum sulphate and aluminum chlorhydrate.
  • Amounts of the anti-microbial age t may range from about 0.1 to about 5%, preferably from about 0.2 to about 1%, optimally about 0.3% by weight of the composition.
  • compositions of the present invention ordinarily contain water as a carrier in amounts ranging from about 5 to about 95%, preferably from about 30 to about 90%, optimally from about 50 to about 85% by weight of the composition.
  • Emollient materials in the form of silicone oils or synthetic esters may be incorporated into the compositions of the present invention. These may be present in amounts ranging from about 0.1 to about 30%, preferably between about 1 and 20% by weight of the composition.
  • Silicone oils may be divided into the volatile and nonvolatile variety.
  • volatile refers to those materials which have a measurable vapor pressure at ambient temperature.
  • Volatile silicone oils are preferably chosen from cyclic or linear polydimethylsiloxanes containing from about 3 to about 9, preferably from about 4 to about 5, silicon atoms.
  • Nonvolatile silicone oils which are suitable as emollients for the compositions of the present invention include polyalkyl siloxanes, polyalkylaryl siloxanes or polyether siloxane copolymers (e.g. dimethicone copolyol).
  • Suitable non-volatile polyalkyl siloxanes include, for example, polydimethyl siloxanes with viscosities of from about 5 to about 100,000 centistokes at 25°C.
  • the preferred nonvolatile emollients which are useful in the present compositions are the polydimethyl siloxanes having viscosities from about 10 to about 400 centistokes at 25°C.
  • Suitable ester emollients include:
  • alkenyl esters of fatty acids having 10 to 20 carbon atoms such as methyl myristate, methyl stearate, oleyl myristate, oleyl stearate, and butyl oleate;
  • ether-esters such as fatty acid esters of ethoxylated fatty alcohols
  • polyhydric alcohol esters such as ethylene glycol mono and di-fatty acid esters, diethylene glycol mono- and di-fatty acid esters, polyethylenen glycol (200-6000) mono- and di-fatty acid esters, propylene glycol mono- and di- fatty acid esters, polypropylene glycol 2000 monooleate, polypropylene glycol 2000 monostearate, ethoxylated propylene glycol monostearate, glyceryl mono- and di-fatty acid esters, polyglycerol poly-fatty esters, ethoxylated glyceryl monostearate, 1,3-butylene glycol monostearate, 1,3-butylene glycol distearate, polyoxyethylene polyol fatty acid ester, sorbitan fatty acid esters, and polyoxyethylene sorbitan fatty acid esters;
  • polyhydric alcohol esters such as ethylene glycol mono and di-fatty acid esters, diethylene glycol mono- and di-fatty acid esters, polyethylene
  • wax esters such as beeswax, spermaceti, myristyl myristate, stearyl stearate;
  • sterols esters such as cholesterol fatty acid esters .
  • the preferred ester emollients are C1-C3 alkyl fatty esters such as methyl stearate, methyl myristate and methyl palmitate.
  • C8-C20 alkyl esters of fatty acids such as cetyl palmitate and myristyl myristate are also particularly preferred.
  • Humectants of the polyhydric alcohol-type may also be included in the compositions of this invention.
  • the humectant helps to increase the effectiveness of the emollient, reduces scaling, stimulates removal of built-up scale and generally improves skin feel.
  • Typical polyhydric alcohols include glycerol, polyalkylene glycols and more preferably alkylene polyols and their derivatives, including propylene glycol, dipropylene glycol, polypropylene glycol, polyethylene glycol and derivatives thereof, sorbitol, hydroxypropyl sorbitol, isoprene glycol, hexylene glycol, 1,3-butylene glycol, 1 , 2 , 6-hexanetriol, ethoxylated glycerol, propoxylated glycerol and mixtures thereof.
  • the amount of humectant may range anywhere from about 0.5 to about 30%, preferably between 1 and 15% by weight of the composition.
  • Thickeners/viscosiflers in amounts up to about 5% by weight of the composition may also be included.
  • the skilled person would appreciated that the precise amount of thickener required may vary depending upon the consistency and thickness of the composition which is desired.
  • Exemplary thickeners are xanthan gum, sodium carboxymethyl cellulose, hydroxyalkyl and alkyl celluloses (particularly hydroxypropyl cellulose) , sclerotium gum and polyacrylamide dispersions in isoparaffm such as those sold by Seppic Inc. under the Sepigel® 305 trademark.
  • Preservatives may also desirably be incorporated into the cosmetic compositions of this invention to protect against the growth of potentially harmful microorganisms.
  • Suitable traditional preservatives include alkyl esters of para- hydroxybenzoic acid.
  • Other preservatives which have more recently come into use include hydantoin derivatives, propionate salts, and a variety of quaternary ammonium compounds.
  • Cosmetic chemists are familiar with appropriate preservatives and routinely choose them to satisfy the preservative challenge test and to provide product stability.
  • preservatives are disodium EDTA, phenoxyethanol, methyl paraben, butyl paraben, propyl paraben, lmidazolidmyl urea (commercially available as Germall 1157), sodium dehydroacetate and benzyl alcohol.
  • the preservatives should be selected having regard for the use of the composition and possible incompatibilities between the preservatives and other ingredients m the emulsion.
  • Preservatives are preferably employed m amounts ranging from about 0.01% to about 2% by weight of the composition .
  • compositions of the present invention may contain glycyrrhizinic acid and salts thereof.
  • ⁇ hese may be of the alpha or beta glycyrrhizinic variety.
  • Particularly useful are the alkali metal and ammonium salts such as disodium and dipotassium glycyrrhizinate. Amounts of these substances may range from about 0.0001 to about 3%, preferably from about 0.01 to about 1.0%, optimally from about 0.1 to about 0.5% by weight of the composition.
  • Colorants and fragrances may also be included in compositions of the present invention. These may be present in amounts ranging from about 0.05 to about 5%, preferably between about 0.1 and about 3% by weight of the composition.
  • compositions of the present invention will have a pH ranging from about 1 to less than 5, preferably from 2 to 4.8, more preferably from 3 to 4.5, optimally from 3.5 to 4.2.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne des compositions cosmétiques de crème de jour basées sur des concentrations relativement élevées d'acide gras, en particulier d'acide stéarique, et comprenant un agent acide bénéfique pour la peau, le pH des compositions allant de 1 à moins de 5. Comme agent bénéfique pour la peau, on préfère en particulier les acides alpha- et bêta-hydroxycarboxyliques, et plus spécifiquement des combinaisons de ces substances.
PCT/EP2001/002343 2000-03-21 2001-03-01 CREME DE JOUR A FAIBLE pH ET A TENEUR ELEVEE EN ACIDE GRAS Ceased WO2001070187A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001256179A AU2001256179A1 (en) 2000-03-21 2001-03-01 Low ph high fatty acid vanishing cream

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0006865.0 2000-03-21
GB0006865A GB0006865D0 (en) 2000-03-21 2000-03-21 Low pH high fatty acid vanishing cream

Publications (1)

Publication Number Publication Date
WO2001070187A1 true WO2001070187A1 (fr) 2001-09-27

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Family Applications (1)

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PCT/EP2001/002343 Ceased WO2001070187A1 (fr) 2000-03-21 2001-03-01 CREME DE JOUR A FAIBLE pH ET A TENEUR ELEVEE EN ACIDE GRAS

Country Status (4)

Country Link
AU (1) AU2001256179A1 (fr)
GB (1) GB0006865D0 (fr)
WO (1) WO2001070187A1 (fr)
ZA (1) ZA200206536B (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6979452B2 (en) 2002-03-22 2005-12-27 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Low pH, high skin friction cosmetic creams
WO2016071878A1 (fr) 2014-11-07 2016-05-12 L'oreal Compositions de crème de jour et leurs utilisations
WO2016164997A1 (fr) * 2015-04-15 2016-10-20 Natura Cosméticos S.A. Compositions pour formulation cosmétique d'hydratation prolongée comprenant du beurre d'ucuuba à haute concentration en acide myristique, et utilisation de ladite formulation pour la préparation d'un produit cosmétique à haut pouvoir hydratant et trousse
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
US11110049B2 (en) 2017-06-23 2021-09-07 The Procter & Gamble Company Composition and method for improving the appearance of skin
US11583488B2 (en) 2020-06-01 2023-02-21 The Procter & Gamble Company Method of improving penetration of a vitamin B3 compound into skin
US11622963B2 (en) 2018-07-03 2023-04-11 The Procter & Gamble Company Method of treating a skin condition

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55127308A (en) * 1979-03-23 1980-10-02 Lion Corp Weakly acidic emulsified cosmetic
JPS57197204A (en) * 1981-05-27 1982-12-03 Shiseido Co Ltd Emulsion cosmetic
JPH03153609A (ja) * 1989-11-11 1991-07-01 Kanebo Ltd 美白化粧料
SU1754105A1 (ru) * 1988-08-09 1992-08-15 Алтайский государственный медицинский институт Защитный крем дл кожи рук
JPH05156240A (ja) * 1991-11-29 1993-06-22 Shimadzu Corp 指先加湿液
JPH07173023A (ja) * 1993-12-16 1995-07-11 Shiseido Co Ltd 皮膚外用剤
US5436007A (en) * 1992-10-23 1995-07-25 Abbott Laboratories Diaper rash lotion
US5482710A (en) * 1993-07-30 1996-01-09 Chesebrough-Pond'usa Co., Division Of Conopco, Inc. Cosmetic composition for treatment of pimples and redness
EP0775486A1 (fr) * 1995-11-23 1997-05-28 Beiersdorf Aktiengesellschaft Compositions anti-bactériennes, anti-mycotiques et anti-virales, basées sur des acides alpha-hydroxyalcanoiques et du squalène
JPH09151112A (ja) * 1995-11-30 1997-06-10 Noevir Co Ltd 微細エマルション組成物
US5723645A (en) * 1996-09-05 1998-03-03 Pacific Corporation Method for preparing 3-aminopropane phosphoric acid
US5871756A (en) * 1995-01-18 1999-02-16 National Starch And Chemical Investment Holding Corporation Cosmetics containing thermally-inhibited starches
WO1999037280A1 (fr) * 1998-01-26 1999-07-29 Unilever Plc Composition servant a eclaircir la peau

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55127308A (en) * 1979-03-23 1980-10-02 Lion Corp Weakly acidic emulsified cosmetic
JPS57197204A (en) * 1981-05-27 1982-12-03 Shiseido Co Ltd Emulsion cosmetic
SU1754105A1 (ru) * 1988-08-09 1992-08-15 Алтайский государственный медицинский институт Защитный крем дл кожи рук
JPH03153609A (ja) * 1989-11-11 1991-07-01 Kanebo Ltd 美白化粧料
JPH05156240A (ja) * 1991-11-29 1993-06-22 Shimadzu Corp 指先加湿液
US5436007A (en) * 1992-10-23 1995-07-25 Abbott Laboratories Diaper rash lotion
US5482710A (en) * 1993-07-30 1996-01-09 Chesebrough-Pond'usa Co., Division Of Conopco, Inc. Cosmetic composition for treatment of pimples and redness
JPH07173023A (ja) * 1993-12-16 1995-07-11 Shiseido Co Ltd 皮膚外用剤
US5871756A (en) * 1995-01-18 1999-02-16 National Starch And Chemical Investment Holding Corporation Cosmetics containing thermally-inhibited starches
EP0775486A1 (fr) * 1995-11-23 1997-05-28 Beiersdorf Aktiengesellschaft Compositions anti-bactériennes, anti-mycotiques et anti-virales, basées sur des acides alpha-hydroxyalcanoiques et du squalène
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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6979452B2 (en) 2002-03-22 2005-12-27 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Low pH, high skin friction cosmetic creams
WO2016071878A1 (fr) 2014-11-07 2016-05-12 L'oreal Compositions de crème de jour et leurs utilisations
CN106999408A (zh) * 2014-11-07 2017-08-01 欧莱雅 雪花膏组合物及其应用
CN106999408B (zh) * 2014-11-07 2021-06-01 欧莱雅 雪花膏组合物及其应用
WO2016164997A1 (fr) * 2015-04-15 2016-10-20 Natura Cosméticos S.A. Compositions pour formulation cosmétique d'hydratation prolongée comprenant du beurre d'ucuuba à haute concentration en acide myristique, et utilisation de ladite formulation pour la préparation d'un produit cosmétique à haut pouvoir hydratant et trousse
US11504315B2 (en) 2015-04-15 2022-11-22 Natura Cosméticos S.A. Compositions for long-lasting moisturizing cosmetic formulation comprising Ucuuba butter with high concentration of myristic acid, as well as the use of said formulation for the preparation of a highly moisturizing cosmetic product and kit
US11110049B2 (en) 2017-06-23 2021-09-07 The Procter & Gamble Company Composition and method for improving the appearance of skin
US11622963B2 (en) 2018-07-03 2023-04-11 The Procter & Gamble Company Method of treating a skin condition
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
US11583488B2 (en) 2020-06-01 2023-02-21 The Procter & Gamble Company Method of improving penetration of a vitamin B3 compound into skin
US11911498B2 (en) 2020-06-01 2024-02-27 The Procter & Gamble Company Low pH skin care composition and methods of using the same

Also Published As

Publication number Publication date
ZA200206536B (en) 2003-08-15
GB0006865D0 (en) 2000-05-10
AU2001256179A1 (en) 2001-10-03

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