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WO2001068849A3 - Canaux ioniques humains - Google Patents

Canaux ioniques humains Download PDF

Info

Publication number
WO2001068849A3
WO2001068849A3 PCT/US2001/007503 US0107503W WO0168849A3 WO 2001068849 A3 WO2001068849 A3 WO 2001068849A3 US 0107503 W US0107503 W US 0107503W WO 0168849 A3 WO0168849 A3 WO 0168849A3
Authority
WO
WIPO (PCT)
Prior art keywords
ion channels
provides
human ion
ion channel
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/007503
Other languages
English (en)
Other versions
WO2001068849A2 (fr
WO2001068849A8 (fr
Inventor
Alla M Karnovsky
Cara L Ruble
Lisa I Linske-O'connell
Jun Wang
Derong Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Priority to EP01920253A priority Critical patent/EP1261713A2/fr
Priority to AU2001247330A priority patent/AU2001247330A1/en
Publication of WO2001068849A2 publication Critical patent/WO2001068849A2/fr
Publication of WO2001068849A8 publication Critical patent/WO2001068849A8/fr
Publication of WO2001068849A3 publication Critical patent/WO2001068849A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des polypeptides de canal ionique ainsi que des polynucléotides qui codent pour ces polypeptides. Elle concerne aussi des vecteurs d'expression, des cellules hôtes et des procédés pour leur production. Elle concerne enfin des méthodes d'identification d'agonistes/antagonistes de canal ionique, utiles pour le traitement de troubles et de maladies de l'homme.
PCT/US2001/007503 2000-03-10 2001-03-09 Canaux ioniques humains Ceased WO2001068849A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01920253A EP1261713A2 (fr) 2000-03-10 2001-03-09 Canaux ioniques humains
AU2001247330A AU2001247330A1 (en) 2000-03-10 2001-03-09 Human ion channels

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US18851800P 2000-03-10 2000-03-10
US18840000P 2000-03-10 2000-03-10
US18851900P 2000-03-10 2000-03-10
US18851700P 2000-03-10 2000-03-10
US60/188,518 2000-03-10
US60/188,517 2000-03-10
US60/188,519 2000-03-10
US60/188,400 2000-03-10
US21581500P 2000-07-05 2000-07-05
US60/215,815 2000-07-05
US21648100P 2000-07-06 2000-07-06
US60/216,481 2000-07-06

Publications (3)

Publication Number Publication Date
WO2001068849A2 WO2001068849A2 (fr) 2001-09-20
WO2001068849A8 WO2001068849A8 (fr) 2002-02-21
WO2001068849A3 true WO2001068849A3 (fr) 2002-06-06

Family

ID=27558790

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/007503 Ceased WO2001068849A2 (fr) 2000-03-10 2001-03-09 Canaux ioniques humains

Country Status (2)

Country Link
AU (1) AU2001247330A1 (fr)
WO (1) WO2001068849A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001271839A1 (en) * 2000-07-05 2002-01-14 Pharmacia And Upjohn Company Human ion channels
AU2002215977A1 (en) * 2000-10-31 2002-05-15 Bayer Aktiengesellschaft Regulation of human serotonin receptor precursor
WO2002061074A1 (fr) * 2001-01-30 2002-08-08 Takeda Chemical Industries, Ltd. Nouvelle proteine et adn la comprenant

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016297A1 (fr) * 1999-09-01 2001-03-08 Ortho-Mcneil Pharmaceutical, Inc. Adn codant une sous-unite humaine 5-ht3-c du recepteur de serotonine 5-ht3
WO2001044283A2 (fr) * 1999-12-14 2001-06-21 Pharmacia & Upjohn Company Canaux ioniques humains

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016297A1 (fr) * 1999-09-01 2001-03-08 Ortho-Mcneil Pharmaceutical, Inc. Adn codant une sous-unite humaine 5-ht3-c du recepteur de serotonine 5-ht3
WO2001044283A2 (fr) * 1999-12-14 2001-06-21 Pharmacia & Upjohn Company Canaux ioniques humains

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COOPER E C ET AL: "Ion channel genes and human neurological disease: Recent progress, prospects, and challenges", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 96, no. 9, 27 April 1999 (1999-04-27), pages 4759 - 4766, XP002174532, ISSN: 0027-8424 *
MARICQ A V ET AL: "Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel", SCIENCE, AAAS. LANCASTER, PA, US, vol. 254, 18 October 1991 (1991-10-18), pages 432 - 437, XP002157173, ISSN: 0036-8075 *
MIYAKE AKIRA ET AL: "Molecular Cloning of Human 5-Hydroxytryptamine-3 Receptor: Heterogeneity in Distribution and Function among Species.", MOLECULAR PHARMACOLOGY, vol. 48, no. 3, 1995, pages 407 - 416, XP001041842, ISSN: 0026-895X *

Also Published As

Publication number Publication date
WO2001068849A2 (fr) 2001-09-20
AU2001247330A1 (en) 2001-09-24
WO2001068849A8 (fr) 2002-02-21

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