[go: up one dir, main page]

WO2001068841A3 - Human dcc-like proteins - Google Patents

Human dcc-like proteins Download PDF

Info

Publication number
WO2001068841A3
WO2001068841A3 PCT/EP2001/002784 EP0102784W WO0168841A3 WO 2001068841 A3 WO2001068841 A3 WO 2001068841A3 EP 0102784 W EP0102784 W EP 0102784W WO 0168841 A3 WO0168841 A3 WO 0168841A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
dcc
regulate
human
human dcc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/002784
Other languages
French (fr)
Other versions
WO2001068841A2 (en
Inventor
Shyam Ramakrishnan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU2001260116A priority Critical patent/AU2001260116A1/en
Publication of WO2001068841A2 publication Critical patent/WO2001068841A2/en
Anticipated expiration legal-status Critical
Publication of WO2001068841A3 publication Critical patent/WO2001068841A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Reagents which regulate human Deleted in Colon Cancer (DCC)-like protein activity can be used to regulate axon outgrowth. Such regulation is particularly useful for modulating neuronal growth regenerative capacity, i.e. the regeneration of axons in adult nervous system after, for example, injury or trauma, for diagnosing genetic neurological defects, and for treating neurodegenerative disease.
PCT/EP2001/002784 2000-03-14 2001-03-13 Human dcc-like proteins Ceased WO2001068841A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001260116A AU2001260116A1 (en) 2000-03-14 2001-03-13 Human dcc-like proteins

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18908700P 2000-03-14 2000-03-14
US60/189,087 2000-03-14
US25488000P 2000-12-13 2000-12-13
US60/254,880 2000-12-13

Publications (2)

Publication Number Publication Date
WO2001068841A2 WO2001068841A2 (en) 2001-09-20
WO2001068841A3 true WO2001068841A3 (en) 2003-01-09

Family

ID=26884765

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/002784 Ceased WO2001068841A2 (en) 2000-03-14 2001-03-13 Human dcc-like proteins

Country Status (2)

Country Link
AU (1) AU2001260116A1 (en)
WO (1) WO2001068841A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120310800B (en) * 2025-06-17 2025-09-30 中国科学院深圳先进技术研究院 Promoter, recombinant vector, adeno-associated virus and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009964A1 (en) * 1990-01-04 1991-07-11 The Johns Hopkins University Gene deleted in colorectal cancer of humans
WO1997014424A1 (en) * 1995-10-16 1997-04-24 The Regents Of The University Of California Neurological drug screens

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009964A1 (en) * 1990-01-04 1991-07-11 The Johns Hopkins University Gene deleted in colorectal cancer of humans
WO1997014424A1 (en) * 1995-10-16 1997-04-24 The Regents Of The University Of California Neurological drug screens

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 14 February 2000 (2000-02-14), SULSTON J.E. ET AL.: "Homo sapiens BAC clone RP11-88L24 from 2, complete sequence.", XP002217056, retrieved from EBI Database accession no. AC023270 *
DATABASE EMBL [online] 18 June 1998 (1998-06-18), ROBERT STRAUSBERG: "ot34c11.s1 Soares_testis_NHT Homo sapiens cDNA clone IMAGE:1618676 3', mRNA sequence", XP002217054, retrieved from EBI Database accession no. AI015495 *
DATABASE EMBL [online] 19 January 1998 (1998-01-19), ROBERT STRAUSBERG: "nx62b11.s1 NCI_CGAP_Alv1 Homo sapiens cDNA clone IMAGE:1266813, mRNA sequence", XP002217058, retrieved from EBI Database accession no. AA746678 *
DATABASE EMBL [online] 23 November 1998 (1998-11-23), ROBERT STRAUSBERG: "ql58h01.x1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:1876561 3' similar to SW:VEGR_RAT P53767 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1", XP002217055, retrieved from EBI Database accession no. AI274972 *
DATABASE EMBL [online] 29 July 1996 (1996-07-29), NAKAMURA Y. ET AL.: "Human Heart cDNA, clone 3NHC3304.", XP002217057, retrieved from EBI Database accession no. C04411 *
KEINO-MASU K ET AL: "DELETED IN COLORECTAL CANCER (DCC) ENCODES A NETRIN RECEPTOR", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 87, no. 2, 18 October 1996 (1996-10-18), pages 175 - 185, XP000941995, ISSN: 0092-8674 *

Also Published As

Publication number Publication date
AU2001260116A1 (en) 2001-09-24
WO2001068841A2 (en) 2001-09-20

Similar Documents

Publication Publication Date Title
ATE256475T1 (en) USE OF FOLLISTATIN IN THE MANUFACTURE OF A MEDICINAL PRODUCT FOR THE TREATMENT OF MUSCLE DISEASES
EP0554383A4 (en)
IL124728A0 (en) Diagnosis and treatment of aur-1 and/or aur-2 related disorders
CA2174971A1 (en) Neural Axon Outgrowth Modulators
CA2232789A1 (en) Method for treating alzheimer's disease using glial cell line-derived neurotrophic factor (gdnf) protein product
ATE346303T1 (en) METHODS FOR DIAGNOSIS, PRODUCTION OF MEDICATIONS AND SCREENING OF SUBSTANCES AS WELL AS BETA-AMYLOID DERIVED PEPTIDES ASSOCIATED WITH ALZHEIMER'S DISEASE
EP1361229A3 (en) Use of Tyrosine Kinase (PYK2) to produce antibodies
WO1997004097A3 (en) Human CTLA-8 and uses of CTLA-8-related proteins
DE3855921D1 (en) Process and deoxyribonucleic acid for the production of tissue factor protein
EP1420031A3 (en) Bone morphogenetic protein (BMP)-18 compositions
WO2001066596A3 (en) Human fgf-23 gene and gene expression products
AU2742892A (en) An anticoagulant substance obtained from urine
WO1998026054A3 (en) Pyk2 related products and methods
ATE259652T1 (en) NEURAL USES OF THE BMP-11
Perry et al. Olfactory neural cells: an untapped diagnostic and therapeutic resource
WO1997023611A3 (en) Nucleic acid sequences of genes of the high mobility group proteins and uses thereof
Schwalb et al. Optic nerve glia secrete a low-molecular-weight factor that stimulates retinal ganglion cells to regenerate axons in goldfish
WO2001068841A3 (en) Human dcc-like proteins
DE3751249D1 (en) Protein L and its subunits, with immunoglobulin binding activity, method of preparation, reagent kit, pharmaceutical preparation and a Peptococcus magnus strain.
WO1997035976A3 (en) Epidermal differentiation factor
DiStefano et al. Regulation of Schwann cell surface and truncated nerve growth factor receptors in vitro by axonal components
AU5659798A (en) Therapeutic composition comprising the kal protein and use of the kal protein for the treatment of retinal, renal, neuronal and neural injury
PT990000E (en) CONJUNCTIVE TISSUE GROWTH FACTOR 3
AUPN674895A0 (en) Synthetic mammalian alpha-N-acetylglucosaminidase and genetic sequences encoding same
AU4654097A (en) Rdgb-proteins

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP