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WO2001068699A3 - Regulation of human neuropeptide y-like g protein-coupled receptor - Google Patents

Regulation of human neuropeptide y-like g protein-coupled receptor Download PDF

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Publication number
WO2001068699A3
WO2001068699A3 PCT/EP2001/002846 EP0102846W WO0168699A3 WO 2001068699 A3 WO2001068699 A3 WO 2001068699A3 EP 0102846 W EP0102846 W EP 0102846W WO 0168699 A3 WO0168699 A3 WO 0168699A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
disease
coupled receptor
regulation
human neuropeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/002846
Other languages
French (fr)
Other versions
WO2001068699A2 (en
Inventor
Shyam Ramakrishnan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to EP01927726A priority Critical patent/EP1272519A2/en
Priority to AU2001254686A priority patent/AU2001254686A1/en
Publication of WO2001068699A2 publication Critical patent/WO2001068699A2/en
Publication of WO2001068699A3 publication Critical patent/WO2001068699A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents which regulate human neuropeptide Y G protein-coupled receptor (NPY- GPCR) protein and reagents which bind to human NPY-GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, obesity, diabetes, anxiety, hypertension, cocaine withdrawal, congestive heart failure, memory enhancement, cardiac and cerebral vasospasm, pheochromocytoma, ganglioneuroblastoma, Huntington's disease, Alzheimer' disease, and Parkinson's disease.
PCT/EP2001/002846 2000-03-16 2001-03-14 Regulation of human neuropeptide y-like g protein-coupled receptor Ceased WO2001068699A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01927726A EP1272519A2 (en) 2000-03-16 2001-03-14 Regulation of human neuropeptide y-like g protein-coupled receptor
AU2001254686A AU2001254686A1 (en) 2000-03-16 2001-03-14 Regulation of human neuropeptide y-like g protein-coupled receptor

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18987700P 2000-03-16 2000-03-16
US60/189,877 2000-03-16
US21074300P 2000-06-12 2000-06-12
US60/210,743 2000-06-12

Publications (2)

Publication Number Publication Date
WO2001068699A2 WO2001068699A2 (en) 2001-09-20
WO2001068699A3 true WO2001068699A3 (en) 2002-05-16

Family

ID=26885571

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/002846 Ceased WO2001068699A2 (en) 2000-03-16 2001-03-14 Regulation of human neuropeptide y-like g protein-coupled receptor

Country Status (3)

Country Link
EP (1) EP1272519A2 (en)
AU (1) AU2001254686A1 (en)
WO (1) WO2001068699A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03003902A (en) 2000-11-03 2004-04-02 Univ California Prokineticin polypeptides, related compositions and methods.
JPWO2003027672A1 (en) * 2001-09-20 2005-01-13 山之内製薬株式会社 Novel screening method using prokineticin receptor
NZ532427A (en) 2001-09-24 2008-07-31 Imp Innovations Ltd Modification of feeding behavior using PYY (peptide YY) and its agonists such as NPY (neuropeptide Y)
CA2461454A1 (en) 2001-09-24 2003-04-03 Oregon Health And Science University Assessment of neurons in the arcuate nucleus to screen for agents that modify feeding behavior
EP1689849A4 (en) * 2003-10-31 2008-06-25 Univ California PROKINETICINE RECEPTOR POLYPEPTIDES AND PRIMATE PROKINETICINES, COMPOSITIONS THEREOF AND METHODS
TWI428346B (en) 2006-12-13 2014-03-01 Imp Innovations Ltd Novel compounds and their effects on feeding behaviour

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014331A1 (en) * 1994-11-07 1996-05-17 Merck & Co., Inc. Modified neuropeptide y receptors
WO1998046620A1 (en) * 1997-04-17 1998-10-22 Millennium Pharmaceuticals, Inc. A novel human g-protein coupled receptor
WO2001053308A1 (en) * 2000-01-19 2001-07-26 Smithkline Beecham Corporation Cloning of a monkey 7tm receptor (axor8)

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014331A1 (en) * 1994-11-07 1996-05-17 Merck & Co., Inc. Modified neuropeptide y receptors
WO1998046620A1 (en) * 1997-04-17 1998-10-22 Millennium Pharmaceuticals, Inc. A novel human g-protein coupled receptor
WO2001053308A1 (en) * 2000-01-19 2001-07-26 Smithkline Beecham Corporation Cloning of a monkey 7tm receptor (axor8)

Also Published As

Publication number Publication date
WO2001068699A2 (en) 2001-09-20
AU2001254686A1 (en) 2001-09-24
EP1272519A2 (en) 2003-01-08

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