[go: up one dir, main page]

WO2001053529A3 - RAPID DETERMINATION OF GENE STRUCTURE USING cDNA SEQUENCE - Google Patents

RAPID DETERMINATION OF GENE STRUCTURE USING cDNA SEQUENCE Download PDF

Info

Publication number
WO2001053529A3
WO2001053529A3 PCT/US2001/001461 US0101461W WO0153529A3 WO 2001053529 A3 WO2001053529 A3 WO 2001053529A3 US 0101461 W US0101461 W US 0101461W WO 0153529 A3 WO0153529 A3 WO 0153529A3
Authority
WO
WIPO (PCT)
Prior art keywords
sequence
regions
exon
gene structure
determined
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/001461
Other languages
French (fr)
Other versions
WO2001053529A2 (en
WO2001053529A9 (en
Inventor
Hans-Ulrich Thomann
Michael S Fitzgerald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oscient Pharmaceuticals Corp
Original Assignee
Genome Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genome Therapeutics Corp filed Critical Genome Therapeutics Corp
Priority to AU29532/01A priority Critical patent/AU2953201A/en
Priority to EP01942674A priority patent/EP1294943A2/en
Priority to CA002398683A priority patent/CA2398683A1/en
Publication of WO2001053529A2 publication Critical patent/WO2001053529A2/en
Anticipated expiration legal-status Critical
Publication of WO2001053529A9 publication Critical patent/WO2001053529A9/en
Publication of WO2001053529A3 publication Critical patent/WO2001053529A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention is drawn to a method of identifying boundaries between exon and non-exon regions of genes. In addition to the boundary between said regions, the boundary between sequence on the 5' and 3' termini of the non-exon region is determined. Furthermore, sequence within the non-exon regions, e.g., sequence at the 5' and 3' termini of the non-exon regions sequence upstream and downstream of the coding regions of the gene (i.e. within the 5' and 3' non-translated regions, respectively) is determined. Therefore, as a result of the method of the present invention, gene structure can be determined without the need to sequence the entire gene. The present invention is useful, for example, in germ line sequence variation analysis.
PCT/US2001/001461 2000-01-20 2001-01-17 RAPID DETERMINATION OF GENE STRUCTURE USING cDNA SEQUENCE Ceased WO2001053529A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU29532/01A AU2953201A (en) 2000-01-20 2001-01-17 Rapid determination of gene structure using cdna sequence
EP01942674A EP1294943A2 (en) 2000-01-20 2001-01-17 RAPID DETERMINATION OF GENE STRUCTURE USING cDNA SEQUENCE
CA002398683A CA2398683A1 (en) 2000-01-20 2001-01-17 Rapid determination of gene structure using cdna sequence

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48812700A 2000-01-20 2000-01-20
US09/488,127 2000-01-20

Publications (3)

Publication Number Publication Date
WO2001053529A2 WO2001053529A2 (en) 2001-07-26
WO2001053529A9 WO2001053529A9 (en) 2002-10-24
WO2001053529A3 true WO2001053529A3 (en) 2003-01-16

Family

ID=23938426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/001461 Ceased WO2001053529A2 (en) 2000-01-20 2001-01-17 RAPID DETERMINATION OF GENE STRUCTURE USING cDNA SEQUENCE

Country Status (4)

Country Link
EP (1) EP1294943A2 (en)
AU (1) AU2953201A (en)
CA (1) CA2398683A1 (en)
WO (1) WO2001053529A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0584446A2 (en) * 1992-03-06 1994-03-02 E.R. SQUIBB & SONS, INC. Microsomal triglyceride transfer protein
EP0613945A2 (en) * 1993-02-25 1994-09-07 The General Hospital Corporation Tumor suppressor gene merlin and uses thereof
WO1995006714A1 (en) * 1993-09-01 1995-03-09 The Trustees Of Columbia University In The City Of New York Isolation and uses of a wilson's disease gene
WO1996036691A1 (en) * 1995-05-16 1996-11-21 Ramot-Univ. Authority For Applied Research And Industrial Development Ltd. Ataxia-telangiectasia gene and its genomic organization
WO1999009147A1 (en) * 1997-08-13 1999-02-25 Icos Corporation Truncated platelet-activating factor acetylhydrolase
WO2000001816A1 (en) * 1998-07-02 2000-01-13 Imperial Cancer Research Technology Limited TUMOUR SUPPRESSOR GENE DBCCR1 AT 9q32-33

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0584446A2 (en) * 1992-03-06 1994-03-02 E.R. SQUIBB & SONS, INC. Microsomal triglyceride transfer protein
EP0613945A2 (en) * 1993-02-25 1994-09-07 The General Hospital Corporation Tumor suppressor gene merlin and uses thereof
WO1995006714A1 (en) * 1993-09-01 1995-03-09 The Trustees Of Columbia University In The City Of New York Isolation and uses of a wilson's disease gene
WO1996036691A1 (en) * 1995-05-16 1996-11-21 Ramot-Univ. Authority For Applied Research And Industrial Development Ltd. Ataxia-telangiectasia gene and its genomic organization
WO1999009147A1 (en) * 1997-08-13 1999-02-25 Icos Corporation Truncated platelet-activating factor acetylhydrolase
WO2000001816A1 (en) * 1998-07-02 2000-01-13 Imperial Cancer Research Technology Limited TUMOUR SUPPRESSOR GENE DBCCR1 AT 9q32-33

Also Published As

Publication number Publication date
AU2953201A (en) 2001-07-31
CA2398683A1 (en) 2001-07-26
WO2001053529A2 (en) 2001-07-26
EP1294943A2 (en) 2003-03-26
WO2001053529A9 (en) 2002-10-24

Similar Documents

Publication Publication Date Title
AU2000260103A1 (en) Xml-robot
WO2003044176A3 (en) Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
FI20012605A0 (en) Method for recovering sugars
ATE263631T1 (en) COMPOSITE SQUEEGEE AND METHOD FOR PRODUCING THE SAME
EP1016985A3 (en) Method and system for topic based cross indexing of text and audio
DE60021590D1 (en) USE OF BACLOFEN FOR THE TREATMENT OF ALCOHOLISM
ATE190061T1 (en) METHOD FOR PRODUCING ALKOXYSILANES
WO2001053529A3 (en) RAPID DETERMINATION OF GENE STRUCTURE USING cDNA SEQUENCE
WO2002036828A3 (en) COMPOSITIONS AND SYSTEMS FOR IDENTIFYING AND COMPARING EXPRESSED GENES (mRNAs) IN EUKARYOTIC ORGANISMS
DE69533626D1 (en) TIOREDIOXINE H FROM TWENTY AND HARD WHEAT AND SIMILAR PROTEINS, THESE ENCODING DNA FRAGMENTS AND METHOD FOR THE PRODUCTION THEREOF
ATA118295A (en) (S) -HYDROXYNITRILLYASE FROM HEVEA BRAZILIENSIS
AU5450599A (en) Method of detecting a dna sequence, a dna sequence, a method of making a dna construct and the use thereof
Suoniemi-Taipale Itämerensuomalaisten kielten prolatiivi
TR199901606T2 (en) Cleaning the DNA in a flow centrifuge.
ZHANG et al. Biodiversity and its conservation in the Yellow River Delta nature reserve
WO2003072724A3 (en) Human analogs of murine deubiquitinating protease genes
EP0829785A3 (en) Signal status propagation in a distributed control system
Mullins The teaching of" Lumen gentium" on the Holy Spirit: The Holy Spirit was sent at Pentecost in order that he might continually sanctify the Church
吴树彪 et al. Morphological characteristics of apomictic embryo in sorghum
Riusech Genetic and Life History Characteristics of Venustaconcha Ellipsiformis and Venustaconcha Pleasii (Bivalvia, Unionidae) in the Ozark Plateaus Region
Hide Like being a kid again
Massing State of planning and extension for sewage and effluent treatment plants in Germany. Results of a survey
Race FISHER'S EXACT TEST
FUKUDA The Commercial Capital as the Social Information Processing Mechanism The New Development of Information Network
Ikeno Hideo Oda (ed.) Africa: Politics and Cultures

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2398683

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 29532/01

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 520370

Country of ref document: NZ

WWE Wipo information: entry into national phase

Ref document number: 2001942674

Country of ref document: EP

AK Designated states

Kind code of ref document: C2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

COP Corrected version of pamphlet

Free format text: PAGES 1/18-18/18, DRAWINGS, REPLACED BY NEW PAGES 1/19-19/19; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 2001942674

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2001942674

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP