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WO2001046465A3 - Dispositif de microanalyse - Google Patents

Dispositif de microanalyse Download PDF

Info

Publication number
WO2001046465A3
WO2001046465A3 PCT/EP2000/013145 EP0013145W WO0146465A3 WO 2001046465 A3 WO2001046465 A3 WO 2001046465A3 EP 0013145 W EP0013145 W EP 0013145W WO 0146465 A3 WO0146465 A3 WO 0146465A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis device
microfluid analysis
microfluid
shaped
microstructure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/013145
Other languages
English (en)
Other versions
WO2001046465A2 (fr
Inventor
Per Andersson
Arvi Aksberg
Gunnar Ekstrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gyros Protein Technologies AB
Original Assignee
Gyros AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1999/010347 external-priority patent/WO2000040750A1/fr
Application filed by Gyros AB filed Critical Gyros AB
Priority to EP00992452A priority Critical patent/EP1239962B1/fr
Priority to DE60035611T priority patent/DE60035611T2/de
Priority to CA002395159A priority patent/CA2395159A1/fr
Priority to US10/169,056 priority patent/US7261859B2/en
Priority to AU44105/01A priority patent/AU4410501A/en
Priority to JP2001546961A priority patent/JP4612262B2/ja
Publication of WO2001046465A2 publication Critical patent/WO2001046465A2/fr
Publication of WO2001046465A3 publication Critical patent/WO2001046465A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Centrifugal Separators (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

L'invention concerne une microstructure, laquelle est destinée à des fluides, est montée dans un disque rotatif (D) et possède une structure (7) définissant un volume en forme de U et reliée à sa base à un segment d'entrée d'une chambre également en forme de U (10).
PCT/EP2000/013145 1998-12-30 2000-12-22 Dispositif de microanalyse Ceased WO2001046465A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP00992452A EP1239962B1 (fr) 1999-12-23 2000-12-22 Dispositif de microanalyse
DE60035611T DE60035611T2 (de) 1999-12-23 2000-12-22 Mikrofluid-analysevorrichtung
CA002395159A CA2395159A1 (fr) 1999-12-23 2000-12-22 Dispositif de microanalyse
US10/169,056 US7261859B2 (en) 1998-12-30 2000-12-22 Microanalysis device
AU44105/01A AU4410501A (en) 1999-12-23 2000-12-22 Microanalysis device
JP2001546961A JP4612262B2 (ja) 1999-12-23 2000-12-22 ミクロ分析装置

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EPPCT/EP99/10347 1999-12-23
PCT/EP1999/010347 WO2000040750A1 (fr) 1998-12-30 1999-12-23 Procede de sequençage d'adn a l'aide d'un dispositif microfluidique
SE0001779A SE0001779D0 (sv) 2000-05-12 2000-05-12 Microanalysis device
SE0001779-8 2000-05-12

Publications (2)

Publication Number Publication Date
WO2001046465A2 WO2001046465A2 (fr) 2001-06-28
WO2001046465A3 true WO2001046465A3 (fr) 2001-12-27

Family

ID=20279665

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/013145 Ceased WO2001046465A2 (fr) 1998-12-30 2000-12-22 Dispositif de microanalyse

Country Status (7)

Country Link
JP (1) JP4612262B2 (fr)
AT (1) ATE367204T1 (fr)
AU (1) AU4410501A (fr)
CA (1) CA2395159A1 (fr)
DE (1) DE60035611T2 (fr)
SE (1) SE0001779D0 (fr)
WO (1) WO2001046465A2 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
US6992278B2 (en) 2002-04-08 2006-01-31 Gyros Ab Homing process
US7189368B2 (en) 2001-09-17 2007-03-13 Gyros Patent Ab Functional unit enabling controlled flow in a microfluidic device
US9186671B2 (en) 2010-10-28 2015-11-17 Roche Diagnostics Operations, Inc. Microfluidic test carrier for apportioning a liquid quantity into subquantities
US9221051B2 (en) 2010-10-29 2015-12-29 Roche Diagnostics Operations, Inc. Microfluidic element for analysis of a sample liquid
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026131B2 (en) 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
US7087203B2 (en) 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
SE0004296D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
SE0004297D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
US7054258B2 (en) 2000-12-08 2006-05-30 Nagaoka & Co., Ltd. Optical disc assemblies for performing assays
US7079468B2 (en) 2000-12-08 2006-07-18 Burstein Technologies, Inc. Optical discs for measuring analytes
US7091034B2 (en) 2000-12-15 2006-08-15 Burstein Technologies, Inc. Detection system for disk-based laboratory and improved optical bio-disc including same
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
US7759067B2 (en) 2001-03-19 2010-07-20 Gyros Patent Ab Method for determining the amount of an analyte with a disc-shaped microfluidic device
EP1483052B1 (fr) * 2001-08-28 2010-12-22 Gyros Patent Ab Microcavite microfluidique de retention microfluidique et autres structures microfluidiques
EP1427530B1 (fr) * 2001-09-17 2010-08-11 Gyros Patent Ab Unite fonctionnelle de gestion des flux d'un dispositif de microfluidique
JP3952019B2 (ja) * 2001-12-28 2007-08-01 株式会社日立ハイテクノロジーズ 抽出装置および化学分析装置並びに化学分析方法
AU2003235970A1 (en) * 2002-04-30 2003-11-17 Arkray, Inc. Analysis instrument, sample analysis method and analysis device using the instrument, and method of forming opening in the instrument
JP4895504B2 (ja) * 2002-04-30 2012-03-14 ユィロス・パテント・アクチボラグ 集中マイクロ流体デバイス（ｅａ）
US7005265B1 (en) 2002-06-20 2006-02-28 Wenhong Fan Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays
JP4575162B2 (ja) 2002-10-13 2010-11-04 ピコセプ アクティーゼルスカブ 二次元ミクロ流体生体分子分離システム
SE0301945D0 (sv) 2003-06-30 2003-06-30 Gyros Ab Confidence determination
JPWO2005012916A1 (ja) * 2003-08-05 2006-09-21 太陽誘電株式会社 試料分析装置及びディスク状試料分析媒体
EP1703982A1 (fr) * 2004-01-06 2006-09-27 Gyros Patent Ab Systeme de chauffage par contact
EP1874469A4 (fr) 2005-04-14 2014-02-26 Gyros Patent Ab Dispositif microfluidique comprenant des valves digitiformes
GB2464721C (en) 2008-10-23 2013-08-14 Biosurfit Sa Jet deflection device
GB2466644B (en) 2008-12-30 2011-05-11 Biosurfit Sa Liquid handling
JP5521454B2 (ja) * 2009-09-15 2014-06-11 凸版印刷株式会社 試料分析チップ、これを用いた試料分析装置及び試料分析方法
GB2476474B (en) 2009-12-22 2012-03-28 Biosurfit Sa Surface plasmon resonance detection system
GB2479139A (en) 2010-03-29 2011-10-05 Biosurfit Sa A liquid distribution and metering device
US9933348B2 (en) 2011-12-08 2018-04-03 Biosurfit, S.A. Sequential aliqoting and determination of an indicator of sedimentation rate
JP5549719B2 (ja) * 2012-09-20 2014-07-16 ブラザー工業株式会社 検査対象受体
WO2017154750A1 (fr) * 2016-03-11 2017-09-14 パナソニック株式会社 Disque d'inspection d'échantillon de liquide et cartouche filtrante utilisée dans ce dernier, corps de disque, plaque de mesure, plaque de détection d'échantillon, système de détection de fluorescence, et procédé de détection de fluorescence

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547547A (en) * 1969-03-13 1970-12-15 Atomic Energy Commission Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
WO2000040750A1 (fr) * 1998-12-30 2000-07-13 Gyros Ab Procede de sequençage d'adn a l'aide d'un dispositif microfluidique

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632908A (en) * 1984-05-03 1986-12-30 Abbott Laboratories Heating system for rotating members
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
AU4047493A (en) * 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
US6299839B1 (en) * 1995-08-31 2001-10-09 First Medical, Inc. System and methods for performing rotor assays
JP2002503336A (ja) * 1997-05-16 2002-01-29 アルバータ リサーチ カウンシル 微量流通システムおよびその使用方法
AU7591998A (en) * 1997-05-23 1998-12-11 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US5916522A (en) * 1997-08-07 1999-06-29 Careside, Inc. Electrochemical analytical cartridge
US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547547A (en) * 1969-03-13 1970-12-15 Atomic Energy Commission Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
WO2000040750A1 (fr) * 1998-12-30 2000-07-13 Gyros Ab Procede de sequençage d'adn a l'aide d'un dispositif microfluidique

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
US7189368B2 (en) 2001-09-17 2007-03-13 Gyros Patent Ab Functional unit enabling controlled flow in a microfluidic device
US6992278B2 (en) 2002-04-08 2006-01-31 Gyros Ab Homing process
US9186671B2 (en) 2010-10-28 2015-11-17 Roche Diagnostics Operations, Inc. Microfluidic test carrier for apportioning a liquid quantity into subquantities
US9221051B2 (en) 2010-10-29 2015-12-29 Roche Diagnostics Operations, Inc. Microfluidic element for analysis of a sample liquid
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus

Also Published As

Publication number Publication date
CA2395159A1 (fr) 2001-06-28
JP4612262B2 (ja) 2011-01-12
JP2003518250A (ja) 2003-06-03
DE60035611D1 (de) 2007-08-30
SE0001779D0 (sv) 2000-05-12
AU4410501A (en) 2001-07-03
DE60035611T2 (de) 2008-05-21
ATE367204T1 (de) 2007-08-15
WO2001046465A2 (fr) 2001-06-28

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