[go: up one dir, main page]

WO2001040796A3 - Matrices de molecules glycanes (glycomatrices) sur la surface de biopuces (glycopuces) et leurs utilisations - Google Patents

Matrices de molecules glycanes (glycomatrices) sur la surface de biopuces (glycopuces) et leurs utilisations Download PDF

Info

Publication number
WO2001040796A3
WO2001040796A3 PCT/EP2000/011975 EP0011975W WO0140796A3 WO 2001040796 A3 WO2001040796 A3 WO 2001040796A3 EP 0011975 W EP0011975 W EP 0011975W WO 0140796 A3 WO0140796 A3 WO 0140796A3
Authority
WO
WIPO (PCT)
Prior art keywords
glycoarrays
relates
present
glycans
absence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/011975
Other languages
English (en)
Other versions
WO2001040796A2 (fr
Inventor
Flavio Ramalho Ortigao
Michael William Mecklenburg
Nicolai Vladimirovich Bovin
Ev Nikolay Eduardovich Nifant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Hybaid GmbH
Original Assignee
Thermo Hybaid GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermo Hybaid GmbH filed Critical Thermo Hybaid GmbH
Priority to AU18610/01A priority Critical patent/AU1861001A/en
Publication of WO2001040796A2 publication Critical patent/WO2001040796A2/fr
Publication of WO2001040796A3 publication Critical patent/WO2001040796A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention porte sur des matrices d'éléments de détection distincts de glycanes (glycomatrices), les glycanes étant immobilisées sur un support solide (glycopuces). La présente invention porte également sur un procédé de production de ces glycomatrices qui consiste à immobiliser une glycane, de préférence, sur la surface de détection enrobée d'une streptavidine par l'intermédiaire d'une biotine ou de son dérivé. La présente invention porte, de plus, sur l'utilisation de ces glycomatrices qui permettent de distinguer des échantillons biologiques complexes, diagnostiquer une maladie ayant une corrélation avec la présence ou l'absence de molécules de liaison glycanes, ainsi que sur des procédés d'identification d'un organisme par génération d'un type de signal provenant d'un échantillon biologique et indiquant la présence ou l'absence d'un organisme particulier. La présente invention porte aussi sur un kit comprenant la glycomatrice utile dans des méthodes diagnostiques.
PCT/EP2000/011975 1999-11-29 2000-11-29 Matrices de molecules glycanes (glycomatrices) sur la surface de biopuces (glycopuces) et leurs utilisations Ceased WO2001040796A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU18610/01A AU1861001A (en) 1999-11-29 2000-11-29 Arrays of glycan molecules (glycoarrays) on the surface of biochips (glycochips)and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99123712.4 1999-11-29
EP99123712 1999-11-29

Publications (2)

Publication Number Publication Date
WO2001040796A2 WO2001040796A2 (fr) 2001-06-07
WO2001040796A3 true WO2001040796A3 (fr) 2001-12-20

Family

ID=8239486

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/011975 Ceased WO2001040796A2 (fr) 1999-11-29 2000-11-29 Matrices de molecules glycanes (glycomatrices) sur la surface de biopuces (glycopuces) et leurs utilisations

Country Status (2)

Country Link
AU (1) AU1861001A (fr)
WO (1) WO2001040796A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10155693A1 (de) * 2001-11-07 2003-05-15 Florian Schweigert Verfahren zum Nachweis von apathogenen Partikeln und deren pathogenen Varianten im Organismus
DE10155692A1 (de) * 2001-11-07 2003-05-22 Florian Schweigert Verfahren zum Nachweis von endogenen und exogenen Stoffen im Organismus
US7592150B2 (en) 2003-12-03 2009-09-22 Glycominds, Ltd Method for diagnosing diseases based on levels of anti-glycan antibodies
AU2004294526A1 (en) 2003-12-03 2005-06-16 Glycominds, Ltd Method for diagnosing diseases based on levels of anti-glycan antibodies
JP2007527539A (ja) * 2004-03-05 2007-09-27 ザ スクリプス リサーチ インスティテュート ハイスループットグリカンマイクロアレイ
US10858384B2 (en) 2004-03-22 2020-12-08 Kode Biotech Limited Synthetic molecule constructs
CA2560781C (fr) 2004-03-22 2011-10-11 Kode Biotech Limited Elements d'ancrage de membranes synthetiques
EP1731540A4 (fr) * 2004-03-31 2011-03-02 Sumitomo Bakelite Co Particule polymere
WO2006068758A2 (fr) * 2004-11-19 2006-06-29 The Scripps Research Institute Detection, prevention et traitement du cancer du sein
EP1926742B1 (fr) 2005-09-21 2016-12-28 Kode Biotech Limited Revêtement de surface de cellule avec un dérivé oligomère d' acide hyaluronique
EP2145895B1 (fr) * 2008-07-08 2013-10-30 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Processus de fabrication de glycochips
US8168396B2 (en) 2009-05-11 2012-05-01 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
WO2012028697A1 (fr) 2010-09-01 2012-03-08 Eth Zürich, Institute Of Molecular Biology And Biophysics Système de purification par affinité sur la base d'une complémentation de brin de donneur
EP2759602A1 (fr) 2013-01-25 2014-07-30 Charité - Universitätsmedizin Berlin Procédés de diagnostic génétique prénatal non invasif
CN114594253A (zh) * 2020-12-03 2022-06-07 中国科学院大连化学物理研究所 一种用于筛选糖结合蛋白竞争性抑制剂的糖芯片的方法
CN117233395A (zh) * 2023-09-28 2023-12-15 上海交通大学 基于液体单向整流的快速诊断芯片及其制造方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007087A1 (fr) * 1989-11-13 1991-05-30 Affymax Technologies N.V. Immobilisation adressable dans l'espace d'anti-ligands sur des surfaces
WO1994024561A1 (fr) * 1993-04-19 1994-10-27 Kurt Nilsson Biodettecteur contenant un glucide immobilise

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007087A1 (fr) * 1989-11-13 1991-05-30 Affymax Technologies N.V. Immobilisation adressable dans l'espace d'anti-ligands sur des surfaces
WO1994024561A1 (fr) * 1993-04-19 1994-10-27 Kurt Nilsson Biodettecteur contenant un glucide immobilise

Also Published As

Publication number Publication date
WO2001040796A2 (fr) 2001-06-07
AU1861001A (en) 2001-06-12

Similar Documents

Publication Publication Date Title
WO2001040796A3 (fr) Matrices de molecules glycanes (glycomatrices) sur la surface de biopuces (glycopuces) et leurs utilisations
Benters et al. Dendrimer‐activated solid supports for nucleic acid and protein microarrays
US20040023413A1 (en) Microscale immobilization of molecules using a hydrogel and methods of use thereof
CA2195875A1 (fr) Dispositif et procedes mettant en oeuvre des matrices de structures de fixation des objets d'analyse
WO2001036681A3 (fr) Detection immunologique d'arn: hybrides d'adn sur jeux ordonnes de microechantillons
WO2005084210A3 (fr) Sondes de detection multiplex
WO2002080647A3 (fr) Methodes et reactifs de capture multiplxee d'analyte, autoassemblage de reseau de surface, et analyse d'echantillons biologiques complexes
WO2000054882A8 (fr) Puces a reseaux d'unites micro-electromagnetiques adressables individuellement
WO2006107312A8 (fr) Nanocapteurs
WO2004099434A3 (fr) Dosages biologiques multiplexes homogenes et kits associes
WO2001075166A3 (fr) Compositions et methodes applicables a la detection et a la quantification d'une expression genique
WO2005080602A3 (fr) Detection immunologique d'hybrides d'arn:adn sur microreseaux
Jamieson et al. Approaches to the rational design of molecularly imprinted polymers developed for the selective extraction or detection of antibiotics in environmental and food samples
Peng et al. Enzyme-linked immunoassay based on imprinted microspheres for the detection of sulfamethazine residue
EP2278334A1 (fr) Dispositif comportant une membrane pour la détection à haut débit d'analytes
Ng et al. Biomedical applications of protein chips
WO2002064829A3 (fr) Methode biochimique et appareil associe permettant de detecter des caracteristiques genetiques
WO2004108957A3 (fr) Procede de diagnostic et/ou de pronostic d'un syndrome septique
US7846746B2 (en) Methods of analysis and labeling of protein-protein interactions
WO2002076608A3 (fr) Procede pour produire un jeu ordonne d'echantillons pour detecter des constituants dans un echantillon biologique
WO2000026409A9 (fr) Procede et systeme d'analyse a reseau amplifie
Li et al. Recent advances in the fabrication and detection of lectin microarrays and their application in glycobiology analysis
Zhang et al. Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray
WO2017059239A1 (fr) Procédés de traitement de matrices biopolymères
WO2001091629A3 (fr) Procedes permettant la detection d'adn endommage et la selection de therapeutiques anticancereux

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)