[go: up one dir, main page]

WO2000035463A1 - Procede de production d'un materiau contenant des cellules de la glande prostatique, materiau contenant des cellules de la glande prostatique, et methodes de traitement de fibromatose de l'uterus, de prostatite chronique et de troubles des fonctions sexuelles chez l'homme selon un procede de transplantation - Google Patents

Procede de production d'un materiau contenant des cellules de la glande prostatique, materiau contenant des cellules de la glande prostatique, et methodes de traitement de fibromatose de l'uterus, de prostatite chronique et de troubles des fonctions sexuelles chez l'homme selon un procede de transplantation Download PDF

Info

Publication number
WO2000035463A1
WO2000035463A1 PCT/RU1999/000489 RU9900489W WO0035463A1 WO 2000035463 A1 WO2000035463 A1 WO 2000035463A1 RU 9900489 W RU9900489 W RU 9900489W WO 0035463 A1 WO0035463 A1 WO 0035463A1
Authority
WO
WIPO (PCT)
Prior art keywords
gland
πρedsτaτelnοy
prostate gland
prostate
material containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU1999/000489
Other languages
English (en)
Russian (ru)
Inventor
Valery Grigorievich Ovsjuk
Nikolai Nikolaevich Skaletsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to UA2000095262A priority Critical patent/UA53780C2/uk
Publication of WO2000035463A1 publication Critical patent/WO2000035463A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Definitions

  • s ⁇ de ⁇ zhaschemu ⁇ le ⁇ i ⁇ eds ⁇ a ⁇ eln ⁇ y gland ⁇ luchenn ⁇ y n ⁇ vym s ⁇ s ⁇ b ⁇ m and ⁇ ⁇ ans ⁇ lan ⁇ l ⁇ giches ⁇ im me ⁇ - give treatment ⁇ ib ⁇ ma ⁇ za ma ⁇ i, ⁇ niches ⁇ g ⁇ ⁇ s ⁇ a ⁇ i ⁇ a and violations of the male sexual function by means of transplantation of the obtained material.
  • the means of receipt of material from insiders of human and animal welfare are known to have been discovered.
  • the method consists in the fact that the pancreatic gland is internally incorporated into human welfare, the short-term profit of a pig or a pig is extracted in a condition.
  • the product is loaded at 0, 1 - 0.3% of the product of collallitine (a preparation containing collagenase) or a mixture of equal parts of 0, 1% of the product is taken in the range of 20-30%.
  • the material containing the beta-cells, obtained by the method indicated above, is known (see also).
  • suspensions For the use of suspensions, food products containing food are used, in particular, the components of the standard food system For this reason, all operating systems are operated under aseptic conditions.
  • the resulting suspension must be stable (see patent of the Russian Federation ⁇ 9 2078590, ⁇ 61 ⁇ 37/00, ⁇ 61 ⁇ 35/48, published on 05/10/97).
  • Iz ⁇ b ⁇ e ⁇ eniya object ⁇ n ⁇ syascheg ⁇ sya ⁇ s ⁇ s ⁇ bu ⁇ lucheniya ma ⁇ e ⁇ iala, s ⁇ de ⁇ zhascheg ⁇ ⁇ le ⁇ i ⁇ eds ⁇ a ⁇ eln ⁇ y gland yavlyae ⁇ sya eg ⁇ u ⁇ schenie increase ga ⁇ an ⁇ i ⁇ vann ⁇ vys ⁇ g ⁇ ⁇ tsen ⁇ a (d ⁇ 90%) from the extraction ne ⁇ v ⁇ ezhdenny ⁇ ⁇ le ⁇ is ⁇ dn ⁇ g ⁇ ma ⁇ e ⁇ iala and cheaper on account ⁇ aza ⁇ ⁇ imeneniya ⁇ e ⁇ men ⁇ a, s ⁇ de ⁇ zhascheg ⁇ ⁇ llagenazu.
  • the objective of the invention related to the material containing the cells of the prostate gland, is to obtain material with a high biological activity.
  • the task of the invention related to methods of treating the fibrosis of a mother, chronic obstruction and abuses of the male function is 4 increase in the effectiveness of treatment due to the use of material with high biological activity.
  • P ⁇ s ⁇ avlennaya task ⁇ eshae ⁇ sya ⁇ em, ch ⁇ ⁇ i ⁇ luchenii ma ⁇ e ⁇ iala, s ⁇ de ⁇ - zhascheg ⁇ ⁇ le ⁇ i ⁇ eds ⁇ a ⁇ eln ⁇ y prostate gland is ⁇ lzuyu ⁇ ⁇ eds ⁇ a ⁇ elnuyu vz ⁇ sl ⁇ g ⁇ m ⁇ l ⁇ d ⁇ g ⁇ or n ⁇ v ⁇ zhdenn ⁇ g ⁇ ⁇ li ⁇ a (v ⁇ zm ⁇ zhn ⁇ is ⁇ lz ⁇ vanie ⁇ eds ⁇ a ⁇ eln ⁇ y gland d ⁇ ug ⁇ g ⁇ mle ⁇ i ⁇ ayuscheg ⁇ ) ⁇ i e ⁇ m extracted gland ⁇ eds ⁇ a ⁇ elnuyu ⁇ myvayu ⁇ in ⁇ as ⁇ v ⁇ e ⁇ en ⁇ sa with d ⁇ bavleniem an ⁇ ibi ⁇ i ⁇ v, ⁇
  • the task posed for the treatment of fibrosis of the mother is resolved by its implementation, while the process is carried out by the patient, it is provided.
  • the prostate gland may be used in small quantities, but in particular it is small.
  • Imeyushih ⁇ y ⁇ ⁇ azyvae ⁇ , ch ⁇ v ⁇ zm ⁇ zhn ⁇ is ⁇ lz ⁇ vanie ⁇ eds ⁇ a ⁇ eln ⁇ y gland ⁇ u ⁇ n ⁇ g ⁇ ⁇ ga ⁇ g ⁇ s ⁇ a and i ⁇ ⁇ l ⁇ d ⁇ v and ⁇ a ⁇ zhe l ⁇ shadey and pigs ⁇ l ⁇ da chel ⁇ ve ⁇ a, n ⁇ naib ⁇ lee d ⁇ s ⁇ u ⁇ nym and cheap ma ⁇ e ⁇ ial ⁇ m yavlyae ⁇ sya ⁇ eds ⁇ a ⁇ elnaya n ⁇ v ⁇ zhdenny ⁇ iron, or m ⁇ l ⁇ dy ⁇ vz ⁇ sly ⁇ ⁇ li ⁇ v.
  • a healthy gland such as a small or large product
  • it For the production of material containing a prostate gland, it extracts a healthy gland, such as a small or large product, and it is suitable for use. Having found a prostate gland from a device, it removes its capsule and a quick connecting tissue with emergency vessels. The pulverized iron is crushed to micro-sizes up to 1 mm and, in addition, it is washed off with the addition of antioxidants. The resulting material is seeded with cultural materials, where the cultural (healthy) medium and the supply of lactating are added. In the case of a shortcut, a raw quick-feed may be used.
  • the resulting material may be used for transplantation not immediately after discharging or if it is necessary to replace the battery for a long period of time.
  • the method of treating fibrosis of the mother is carried out with the use of the material, which consumes the cells of the prostate gland, obtained by using it, is used.
  • the simplest version of the technique, effective and the least effective for the patient, is the introduction of a material that is safe for the non-carcinoma of the gland.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cette invention se rapporte au domaine de la médecine et concerne un procédé de production d'un matériau qui contient des cellules de la glande prostatique issues de lapins nouveau-nés, jeunes et adultes. Cette invention concerne également le matériau contenant les cellules de la glande prostatique obtenues selon ce procédé, ainsi que des procédés de transplantation qui permettent de traiter la fibromatose de l'utérus, la prostatite chronique et les troubles des fonctions sexuelles chez l'homme par transplantation du matériau contenant des cellules de la glande prostatique. Cette invention concernant la production du matériau et le matériau proprement dit consiste à utiliser la glande prostatique de mammifères. La glande prostatique extraite est lavée puis découpée en fragments. On sème ensuite le matériau obtenu sur des tapis de culture en ajoutant un milieu de culture (croissance) ainsi que du sérum de mammifères, et l'on assure un mode d'incubation optimal. Cette invention, qui concerne également des méthodes de traitement de fibromatose de l'utérus, de prostatite chronique et de troubles des fonctions sexuelles chez l'homme, consiste à produire le matériau de transplantation contenant des cellules de la glande prostatique selon le procédé susmentionné, lequel matériau peut être transplanté dans divers organes et tissus.
PCT/RU1999/000489 1998-12-17 1999-12-16 Procede de production d'un materiau contenant des cellules de la glande prostatique, materiau contenant des cellules de la glande prostatique, et methodes de traitement de fibromatose de l'uterus, de prostatite chronique et de troubles des fonctions sexuelles chez l'homme selon un procede de transplantation Ceased WO2000035463A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UA2000095262A UA53780C2 (uk) 1998-12-17 1999-12-16 Спосіб отримання матеріалу, що містить клітини передміхурової залози, матеріал, що містить клітини передміхурової залози, та способи лікування фіброматозу матки, хронічного простатиту та порушень чоловічої статевої функції методом трансплантації

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU98122714 1998-12-17
RU98122714/14A RU2135195C1 (ru) 1998-12-17 1998-12-17 Способ получения материала, содержащего клетки предстательной железы, материал, содержащий клетки предстательной железы, и способы лечения фиброматоза матки, хронического простатита и нарушений мужской половой функции методом трансплантации

Publications (1)

Publication Number Publication Date
WO2000035463A1 true WO2000035463A1 (fr) 2000-06-22

Family

ID=20213481

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU1999/000489 Ceased WO2000035463A1 (fr) 1998-12-17 1999-12-16 Procede de production d'un materiau contenant des cellules de la glande prostatique, materiau contenant des cellules de la glande prostatique, et methodes de traitement de fibromatose de l'uterus, de prostatite chronique et de troubles des fonctions sexuelles chez l'homme selon un procede de transplantation

Country Status (3)

Country Link
RU (1) RU2135195C1 (fr)
UA (1) UA53780C2 (fr)
WO (1) WO2000035463A1 (fr)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888981A (en) * 1974-02-13 1975-06-10 American Home Prod Treatment of benign prostatic hypertrophy
EP0224386A2 (fr) * 1985-11-22 1987-06-03 Fink GmbH Utilisation de ruscogénines pour le traitement des maladies de la prostate
EP0459666A2 (fr) * 1990-05-31 1991-12-04 Pfizer Inc. Médicament contre l'impuissance
WO1994002130A1 (fr) * 1992-07-20 1994-02-03 Massachusetts Institute Of Technology Procede pour diminuer les cicatrices consecutives a des blessures a l'aide d'antagonistes du calcium seuls ou en combinaison avec un steroide
WO1997026878A1 (fr) * 1996-01-29 1997-07-31 Eli Lilly And Company Methode pour reduire les fibromatoses musculoaponevrotiques (tumeurs desmoides)
RU2087152C1 (ru) * 1995-07-26 1997-08-20 Российская медицинская академия последипломного образования Способ лечения инфекционно-воспалительных заболеваний органов репродуктивной системы у мужчин
RU2089204C1 (ru) * 1994-11-24 1997-09-10 Научно-производственное объединение "Иммунопрепарат" Способ получения пептидов, восстанавливающих функцию предстательной железы
RU2112504C1 (ru) * 1996-12-24 1998-06-10 Открытое акционерное общество "Нижегородский химико-фармацевтический завод" Средство для лечения заболеваний предстательной железы "витапрост"

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1740004A1 (ru) * 1989-06-19 1992-06-15 1-Й Ленинградский Медицинский Институт Им.Акад.И.П.Павлова Способ дл лечени хронического простатита
RU2058780C1 (ru) * 1992-11-17 1996-04-27 Совместное русско-американское акционерное общество закрытого типа "Неофарм" Средство, обладающее тонизирующим действием на гладкую мускулатуру вен, мочевого пузыря и предстательной железы
RU2026643C1 (ru) * 1992-12-25 1995-01-20 Зыбин Дмитрий Владимирович Способ лечения больных с нарушением мужской половой функции методом трансплантации
RU2078590C1 (ru) * 1995-12-04 1997-05-10 Акопян Андрей Степанович Способ лечения хронического простатита

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888981A (en) * 1974-02-13 1975-06-10 American Home Prod Treatment of benign prostatic hypertrophy
EP0224386A2 (fr) * 1985-11-22 1987-06-03 Fink GmbH Utilisation de ruscogénines pour le traitement des maladies de la prostate
EP0459666A2 (fr) * 1990-05-31 1991-12-04 Pfizer Inc. Médicament contre l'impuissance
WO1994002130A1 (fr) * 1992-07-20 1994-02-03 Massachusetts Institute Of Technology Procede pour diminuer les cicatrices consecutives a des blessures a l'aide d'antagonistes du calcium seuls ou en combinaison avec un steroide
RU2089204C1 (ru) * 1994-11-24 1997-09-10 Научно-производственное объединение "Иммунопрепарат" Способ получения пептидов, восстанавливающих функцию предстательной железы
RU2087152C1 (ru) * 1995-07-26 1997-08-20 Российская медицинская академия последипломного образования Способ лечения инфекционно-воспалительных заболеваний органов репродуктивной системы у мужчин
WO1997026878A1 (fr) * 1996-01-29 1997-07-31 Eli Lilly And Company Methode pour reduire les fibromatoses musculoaponevrotiques (tumeurs desmoides)
RU2112504C1 (ru) * 1996-12-24 1998-06-10 Открытое акционерное общество "Нижегородский химико-фармацевтический завод" Средство для лечения заболеваний предстательной железы "витапрост"

Also Published As

Publication number Publication date
RU2135195C1 (ru) 1999-08-27
UA53780C2 (uk) 2003-02-17

Similar Documents

Publication Publication Date Title
DE69535328T2 (de) In-vitro wachstum von langerhans'schen inseln und ihre verwendungen
Baer The treatment of chronic osteomyelitis with the maggot (larva of the blow fly)
W. BARRINGTON Gastric digestion in the lower vertebrates
Mitrovic Development of the articular cavity in paralyzed chick embryos and in chick embryo limb buds cultured on chorioallantoic membranes
Baer The classic: the treatment of chronic osteomyelitis with the maggot (larva of the blow fly)
CN101072866A (zh) 通过施用rna改变细胞性质的方法
Fell The role of organ cultures in the study of vitamins and hormones
WO2001076611A1 (fr) Procede de preparation de transplant cellulaire a partir de tissus foetaux
CN103596577A (zh) 药物组合物及其局部用途
JP2023054120A (ja) オルガノイドの生体移植用組成物
WO1990012584A1 (fr) Preparation ayant un action anti-inflammatoire, lactogene et stimulante, et procede pour sa fabrication
SCHILLER Echinococcosis in North America
WO2000035463A1 (fr) Procede de production d'un materiau contenant des cellules de la glande prostatique, materiau contenant des cellules de la glande prostatique, et methodes de traitement de fibromatose de l'uterus, de prostatite chronique et de troubles des fonctions sexuelles chez l'homme selon un procede de transplantation
Grossman The physiology of secretin
RU2135193C1 (ru) Способ получения материала, содержащего бета-клетки поджелудочной железы, для трансплантации больным сахарным диабетом с использованием феномена миграции клеток, материал, содержащий бета-клетки поджелудочной железы, для трансплантации больным сахарным диабетом и способ лечения сахарного диабета методом его трансплантации
RU2118524C1 (ru) Способ получения сульфатированных гликозаминогликанов
KR860001576B1 (ko) 인체 세포증식 촉진활성인자의 제조방법
WO2005067948A2 (fr) Medicament biologique pour le traitement de diverses maladies dues a differents virus, infection bacterienne
Gray et al. Insulin and glucagon responses of transplanted intrasplenic pancreatic islets
WO1991000098A1 (fr) Preparation anti-inflammatoire et son procede d'obtention
CN1486190A (zh) 包含分离自半枝莲活性级分的组合物及其使用方法
DE60120131T2 (de) Antiangiogene Eigenschaften von Vascostatin und Fragmenten und Varianten davon
ITO et al. STUDIES ON THE SALIVARY GLAND HORMONES IN TISSUE CULTURE. I. THE EFFECTS OF PAROTIN ON THE LONGITUDINAL GROWTH AND CALCIUM DEPOSITION OF CHICK EMBRYO FEMORA IN VITRO STUDIES ON THE SALIVARY GLAND HORMONES. XXVIII
서주희 Anti-Inflammatory Effects of Polydeoxyribonucleotide and Adipose Tissue-Derived Mesenchymal Stem Cells in a Canine Cell Model of Osteoarthritis
Burrows Studies to determine the biological significance of the vitamins.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA GE UA US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase