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WO2000033789A3 - Inhalation powders - Google Patents

Inhalation powders Download PDF

Info

Publication number
WO2000033789A3
WO2000033789A3 PCT/US1999/028608 US9928608W WO0033789A3 WO 2000033789 A3 WO2000033789 A3 WO 2000033789A3 US 9928608 W US9928608 W US 9928608W WO 0033789 A3 WO0033789 A3 WO 0033789A3
Authority
WO
WIPO (PCT)
Prior art keywords
fraction
particle size
inhalation powders
present
excipient powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/028608
Other languages
French (fr)
Other versions
WO2000033789A2 (en
Inventor
Jonathan Kenneth Embleton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Priority to AU20383/00A priority Critical patent/AU2038300A/en
Publication of WO2000033789A2 publication Critical patent/WO2000033789A2/en
Publication of WO2000033789A3 publication Critical patent/WO2000033789A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to inhalable drugs in particulate form. More specifically, the present invention is directed to an excipient powder that comprises a coarse first fraction having a particle size of 10νm, a fine second fraction having a particle size of no more than 10νm and a third fraction consisting of ternary agents. The excipient powder has been found to be beneficial in the administration of phamarceuticals to the pulmonary system.
PCT/US1999/028608 1998-12-04 1999-12-03 Inhalation powders Ceased WO2000033789A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20383/00A AU2038300A (en) 1998-12-04 1999-12-03 Inhalation powders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9826783.4 1998-12-04
GBGB9826783.4A GB9826783D0 (en) 1998-12-04 1998-12-04 Inhalation powders

Publications (2)

Publication Number Publication Date
WO2000033789A2 WO2000033789A2 (en) 2000-06-15
WO2000033789A3 true WO2000033789A3 (en) 2000-09-14

Family

ID=10843720

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/028608 Ceased WO2000033789A2 (en) 1998-12-04 1999-12-03 Inhalation powders

Country Status (3)

Country Link
AU (1) AU2038300A (en)
GB (1) GB9826783D0 (en)
WO (1) WO2000033789A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI991582A1 (en) 1999-07-16 2001-01-16 Chiesi Farma Spa DUST CONSTITUTED FROM PARTICLES HAVING THE PERFECTLY SMOOTH SURFACE FOR USE AS VEHICLES FOR THE PREPARATION OF INALA MIXTURES
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
PE20011227A1 (en) * 2000-04-17 2002-01-07 Chiesi Farma Spa PHARMACEUTICAL FORMULATIONS FOR DRY POWDER INHALERS IN THE FORM OF HARD AGGLOMERATES
GB0014851D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
DK1913939T3 (en) * 2000-06-27 2017-09-18 Vectura Ltd Formulations for use in inhalers
JP5698423B2 (en) * 2000-06-27 2015-04-08 ベクトゥラ・リミテッド Process for the production of particles for use in pharmaceutical compositions
PT1920763E (en) 2000-11-30 2014-06-25 Vectura Ltd Pharmaceutical compositions for inhalation
DE60140268D1 (en) 2000-11-30 2009-12-03 Vectura Ltd PARTICLES FOR USE IN A PHARMACEUTICAL COMPOSITION
ES2613391T3 (en) 2005-02-10 2017-05-24 Glaxo Group Limited Lactose manufacturing procedures using preclassification techniques and pharmaceutical formulations formed therefrom
GB0613161D0 (en) 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
US8726874B2 (en) 2012-05-01 2014-05-20 Ford Global Technologies, Llc Cylinder bore with selective surface treatment and method of making the same
WO2014007771A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising muscarinic receptor antagonist
WO2014007766A1 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Dry powder inhalers comprising a carrier other than lactose
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
CN104274427A (en) * 2013-07-03 2015-01-14 陆克塞纳医药公司 Novel aerosol formulations of granisetron and uses thereof
CN104274426A (en) * 2013-07-03 2015-01-14 陆克塞纳医药公司 Novel aerosol formulations of ondansetron and uses thereof
WO2016005434A1 (en) * 2014-07-09 2016-01-14 Arven Ilac Sanayi Ve Ticaret A.S. Novel process for the preparation of dry powder formulations
JP6684275B2 (en) * 2014-10-08 2020-04-22 ザンボン ソシエタ ペル アチオニ Pharmaceutical composition containing budesonide and formoterol
CA2962531C (en) 2014-10-08 2023-05-23 Eratech S.R.L. Composition comprising at least one dry powder obtained by spray drying to increase the stability of the formulation
CN106692116A (en) * 2015-11-15 2017-05-24 复旦大学 Capsule-type inhalation aerosol powder containing isoforskolin
AU2020356243A1 (en) 2019-09-24 2022-03-24 Chiesi Farmaceutici S.P.A. Novel carrier particles for dry powder formulations for inhalation
KR102488719B1 (en) * 2020-12-03 2023-01-13 충북대학교 산학협력단 Dry powder inhalation formulation containing selexipag and manufacturing method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation

Also Published As

Publication number Publication date
AU2038300A (en) 2000-06-26
GB9826783D0 (en) 1999-01-27
WO2000033789A2 (en) 2000-06-15

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