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WO2000009084A3 - Formulation pharmaceutique - Google Patents

Formulation pharmaceutique Download PDF

Info

Publication number
WO2000009084A3
WO2000009084A3 PCT/GB1999/002527 GB9902527W WO0009084A3 WO 2000009084 A3 WO2000009084 A3 WO 2000009084A3 GB 9902527 W GB9902527 W GB 9902527W WO 0009084 A3 WO0009084 A3 WO 0009084A3
Authority
WO
WIPO (PCT)
Prior art keywords
gel composition
biodegradable microparticles
gel
physiological
microparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1999/002527
Other languages
English (en)
Other versions
WO2000009084A2 (fr
Inventor
Nicola Kim Rylance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Healthcare UK Ltd
Original Assignee
Quadrant Healthcare UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadrant Healthcare UK Ltd filed Critical Quadrant Healthcare UK Ltd
Priority to EP99936846A priority Critical patent/EP1105095A2/fr
Priority to CA002340177A priority patent/CA2340177A1/fr
Priority to JP2000564587A priority patent/JP2002522467A/ja
Priority to AU51820/99A priority patent/AU5182099A/en
Publication of WO2000009084A2 publication Critical patent/WO2000009084A2/fr
Publication of WO2000009084A3 publication Critical patent/WO2000009084A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Un gel comprend des microparticules biodégradables contenant une matière formant paroi laquelle est relativement insoluble à un pH physiologique, dans laquelle la phase liquide du gel est aqueuse, tamponnée à un pH physiologique.
PCT/GB1999/002527 1998-08-11 1999-08-02 Formulation pharmaceutique Ceased WO2000009084A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99936846A EP1105095A2 (fr) 1998-08-11 1999-08-02 Formulation pharmaceutique
CA002340177A CA2340177A1 (fr) 1998-08-11 1999-08-02 Formulation pharmaceutique
JP2000564587A JP2002522467A (ja) 1998-08-11 1999-08-02 医薬処方物
AU51820/99A AU5182099A (en) 1998-08-11 1999-08-02 Pharmaceutical formulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9817470.9 1998-08-11
GBGB9817470.9A GB9817470D0 (en) 1998-08-11 1998-08-11 Pharmaceutical formulation

Publications (2)

Publication Number Publication Date
WO2000009084A2 WO2000009084A2 (fr) 2000-02-24
WO2000009084A3 true WO2000009084A3 (fr) 2000-06-02

Family

ID=10837065

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/002527 Ceased WO2000009084A2 (fr) 1998-08-11 1999-08-02 Formulation pharmaceutique

Country Status (6)

Country Link
EP (1) EP1105095A2 (fr)
JP (1) JP2002522467A (fr)
AU (1) AU5182099A (fr)
CA (1) CA2340177A1 (fr)
GB (1) GB9817470D0 (fr)
WO (1) WO2000009084A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US8936813B2 (en) 2001-11-01 2015-01-20 Novartis Ag Spray drying methods and related compositions

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
BR102012011209A2 (pt) * 2012-05-11 2014-03-25 Bioactive Biomateriais Ltda Material tridimensional polimérico biodegradável e processo de preparo de material tridimensional polimérico biodegradável

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018164A1 (fr) * 1991-04-10 1992-10-29 Delta Biotechnology Limited Preparation d'agents diagnostiques
EP0563876A2 (fr) * 1992-04-01 1993-10-06 Inverni Della Beffa S.P.A. Microgranulés biodégradables et leurs applications pharmaceutiques et cosmétologiques
WO1993025221A1 (fr) * 1992-06-11 1993-12-23 Alkermes Controlled Therapeutics, Inc. Systeme d'apport de medicament sous forme d'erythropoietine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2657018A1 (fr) * 1990-01-12 1991-07-19 Merck Sharp & Dohme Composition ophtalmique fluide a base de microparticules lipidiques contenant au moins un principe actif et son procede de preparation.
FR2778847A1 (fr) * 1998-05-20 1999-11-26 Jean Pierre Perraud Implant injectable en sous gingival resorbable, constitue de microspheres a liberation prolongee et chargees en principes actifs et en suspension dans un gel vecteur

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018164A1 (fr) * 1991-04-10 1992-10-29 Delta Biotechnology Limited Preparation d'agents diagnostiques
EP0563876A2 (fr) * 1992-04-01 1993-10-06 Inverni Della Beffa S.P.A. Microgranulés biodégradables et leurs applications pharmaceutiques et cosmétologiques
WO1993025221A1 (fr) * 1992-06-11 1993-12-23 Alkermes Controlled Therapeutics, Inc. Systeme d'apport de medicament sous forme d'erythropoietine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US8936813B2 (en) 2001-11-01 2015-01-20 Novartis Ag Spray drying methods and related compositions

Also Published As

Publication number Publication date
GB9817470D0 (en) 1998-10-07
CA2340177A1 (fr) 2000-02-24
WO2000009084A2 (fr) 2000-02-24
JP2002522467A (ja) 2002-07-23
EP1105095A2 (fr) 2001-06-13
AU5182099A (en) 2000-03-06

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