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WO2000009083A1 - Compositions de nettoyage stables contenant des agents reactifs - Google Patents

Compositions de nettoyage stables contenant des agents reactifs Download PDF

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Publication number
WO2000009083A1
WO2000009083A1 PCT/IB1999/001423 IB9901423W WO0009083A1 WO 2000009083 A1 WO2000009083 A1 WO 2000009083A1 IB 9901423 W IB9901423 W IB 9901423W WO 0009083 A1 WO0009083 A1 WO 0009083A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition according
composition
chosen
agent
fragrance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB1999/001423
Other languages
English (en)
Inventor
Carolyn Engelhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Priority to CA002338586A priority Critical patent/CA2338586A1/fr
Priority to EP99935008A priority patent/EP1105091A1/fr
Priority to AU50612/99A priority patent/AU5061299A/en
Priority to JP2000564586A priority patent/JP2002522466A/ja
Publication of WO2000009083A1 publication Critical patent/WO2000009083A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations

Definitions

  • the present invention relates to stable personal cleansing compositions comprising: at least one stabilizing agent chosen from specific ethoxylated solubilizers, particularly polyethylene glycol ("PEG") ethers of fatty alcohols; at least one active agent, particularly a lipophilic compound; and at least one surfactant.
  • PEG polyethylene glycol
  • the present invention also relates to a process for stabilizing cleansing compositions containing at least one active agent, particularly at least one lipophilic compound.
  • Personal cleansing compositions are useful for maintaining good skin hygiene. In so doing, personal cleansing compositions should be able to cleanse the skin of excess sebum, make-up residues, and particularly compositions which have waterproof or non-transfer properties.
  • Conventional personal cleansing compositions use soaps based on alkali salts of fatty acids, synthetic surfactants, or mixtures of soaps and synthetic surfactants. Typically, these compositions are in the form of solid soap bars.
  • These conventional compositions have several disadvantages. In particular, conventional compositions can be harsh, removing the hydro-lipidic film of the skin, leaving the skin extremely dry. Moreover, these soap bar compositions can exhibit poor rinsability, leaving a film on the skin after rinsing. Cleansing compositions based only on synthetic surfactants, i.e., without soaps, can have problems with their foam. Often the foam obtained with these compositions is abundant but does not have the fine and dense texture offered by soaps.
  • Personal cleansing compositions can also act as delivery systems for active agents.
  • Active agents include compounds typically identified as such by those of ordinary skill in the art, for example moisturizers, emollients, and uv filters, as well as fragrances.
  • certain active agents can disrupt the stability of conventional cleansing compositions. Lipophilic compounds, and fragrances in particular, especially at higher concentrations, can disrupt the stability of cleansing compositions and often suppress foam.
  • the present invention relates to stable personal cleansing compositions comprising at least one stabilizing agent chosen from ethoxylated solubilizing agents, at least one active agent, and at least one surfactant.
  • These compositions can further comprise water.
  • the present invention also relates to a process for stabilizing personal cleansing compositions comprising at least one active agent and at least one surfactant by including therein at least one stabilizing agent chosen from ethoxylated solubilizing agents.
  • the subject of the present invention is a personal cleansing composition containing at least one active agent and at least one surfactant, and further comprising at least one stabilizing agent, wherein the viscosity profile of the composition remains relatively constant, i.e., the composition is stable.
  • Active agents useful in the present invention include, but are not limited to, lipophilic compounds such as retinol or its derivatives, vitamin E or its derivatives, bisabolol, oils, particularly vegetable oils, and fragrances. More preferably, the active agent is a fragrance.
  • the surfactant used in the present invention is preferably an anionic surfactant.
  • the stabilizing agent is preferably chosen from ethoxylated solubilizing agents.
  • the stabilizing agent is chosen from polyethylene glycol ethers of fatty alcohols.
  • the inventive composition can have conditioning properties and foaming properties as well.
  • a “stable" composition in accordance with the present invention is either a composition whose viscosity does not change more than 20% from its initial value within 8 weeks at 45°C or a composition whose initial viscosity is at a level useful in a cleansing composition, e.g., not lower than about 5000 cps. "Initial viscosity" is the viscosity 24 hours after manufacture of a cleansing composition.
  • the stability of a compound can be a predictor of shelf life. For example, a compound whose viscosity does not change more than 20% within 8 weeks at 45°C might have a shelf life of about two years at room temperature.
  • the present composition thus has the stability characteristics discussed above and contains at least one active agent, at least one surfactant, and at least one stabilizing agent chosen from specific solubilizers.
  • conventional cleansing compositions that do not contain solubilizers can exhibit a change in viscosity of greater than 20% after 8 weeks at 45°C.
  • solubilizers including ethoxylated materials, to help solubilize fragrances
  • some solubilizers can disrupt the viscosity of cleansing compositions, causing the initial viscosity to be too low to achieve the objectives of the present invention, e.g., about 5000 cps or less.
  • the ethoxylated solubilizer PPG-26 Buteth-26 PEG-40 hydrogenated castor oil disrupts the viscosity of a fragranced cleansing composition, resulting in an initial viscosity of less than about 5000 cps.
  • ethoxylated solubilizing agents particularly polyethylene glycol (PEG) ethers of fatty alcohols
  • PEG polyethylene glycol
  • cleansing compositions comprising these specific ethoxylated solubilizing agents, particularly cleansing compositions which also comprise a fragrance, do not exhibit the change in viscosity and do not have unacceptably low viscosities, as described above.
  • PEG ethers of fatty alcohols used according to the invention may preferably be chosen from compounds having formula (I), below:
  • R is chosen from alkyl and alkylene fatty chains having from about 10 to about 18 carbons; and, n represents an average value of from about 10 to about 30.
  • R therefore refers to the fatty alcohol chain and n shows the average number of moles of ethylene oxide or the degree of ethoxylation.
  • the solubilizing properties of the compositions are related to R, n, and the degree of saturation of the fatty chain. The longer the chain making up R, the more lipophilic the compound, and the higher the n, the more hydrophilic the compound.
  • a person of ordinary skill in the art will know how to vary the parameters to achieve a compound which is effective as a solubilizer and, similarly, that the choice of n and R depend on the compound that is being solubilized.
  • n and R represent preferred embodiments, and that depending on how each parameter is selected, R and n may vary outside the preferred range .
  • the inventor has used the term "about" in defining n and R to represent values, including average values, in combination sufficient to achieve stabilization of compositions of the invention containing active agents, particularly lipophilic active agents, such as fragrances.
  • the preferred PEG ethers of fatty alcohols of formula (I) have an R with a chain length from 10 to 16 carbons, even more preferably 14 to 16, and an average n value from 15 to 25, even more preferably 20.
  • Particularly preferred are CETETH-20, which contains 16 carbons in its fatty chain, i.e., including the portion of its fatty chain corresponding to R in formula (I) above as well as the two additional carbon atoms on either side of R, and an n of average value 20, or STEARETH-20, which has a 18-carbon chain (where the chain length is as defined above for CETETH-20) and an n of average value 20, both available from ICI Americas.
  • the fragrance is present in the inventive composition in an amount up to 5%, preferably in an amount ranging from 2 to 5%. Furthermore, the ratio of the PEG ethers of fatty alcohols to the fragrance in the inventive composition can range from about 1 :4 to about 5:1 , based on weight.
  • the fragrance(s) can be chosen from conventional fragrances suitable for use in personal cleansing compositions.
  • composition of the present invention can also contain one or more anionic surfactants, or one or more other surfactants.
  • Anionic surfactants suitable for use in the inventive composition include, but are not limited to alkyl sulfates, alkyl ether sulfates, alkali metal alkylarylsulfonates, alkali metal, alkanolamines, salts of alkyl polyether carboxylic acids, salts of alkylphenyl polyether carboxylic acids, and N-acylamino acids.
  • anionic surfactants are preferably present in the composition in concentrations of from 8% to 25% and can provide foam properties.
  • a preferred formulation of the present composition contains: a) PEG ether(s) of fatty alcohols in an amount of from 2% to 25%, b) anionic surfactant(s) in an amount of from 8% to 25%, c) fragrance(s) in an amount of from 2% to 5% and d) water.
  • amphoteric surfactants may be used alone, or preferably, in combination with the anionic surfactants.
  • certain cleansing compositions such as baby shampoos, that are intended to be particularly mild may contain amphoteric surfactants.
  • Preferred classes of amphoteric surfactants include: N-alkylamino acids, N-alkylamine oxides, alkylimidazolines, betaines containing fatty chains, or amidobetaines derived from fatty acids, or salts of amino acids such as N-lauryl ⁇ - alanine and N-stearyl ⁇ -alanine.
  • Preferred nonionic surfactants of the following classes may be used: alkanolamides, alkyl ethers of polyglycerols, alkyl ethers of polyethylene glycols, alkyl glucosides, copolymers of ethylene oxide and propylene oxide.
  • composition according to the invention is advantageously in a thickened form, preferably a gel. Therefore, the composition preferably also comprises at least one thickener or gelling agent.
  • the thickeners or gelling agents can be either synthetic or natural and are preferably chosen from carboxylic acid polymers, crosslinked polyacrylate polymers, polyacrylamide polymers, polysaccharides, gums, gelatins, vinyl ether/maleic anhydride copolymers, and crosslinked poly (N- vinylpyrrolidones).
  • the at least one thickener or gelling agent is preferably present in the composition in an amount ranging from 0.1% to 2%, more preferably from 0.25% to 1% and even more preferably from 0.4% to 0.8%.
  • the thickener or gelling agent can be a single compound as well as a mixture of two or more compounds.
  • composition of the present invention can also comprise any ingredient usually used by any person of skill in the art in the personal care area.
  • ingredients can be, but are not limited to, adjuvants such as natural and synthetic polymers, colorants, preservatives, antioxidants, medicaments, moisturizers, sunscreen agents, germicides, deodorants, opacifiers, pearlizing agents, oils, waxes, thickeners for the oily phase, proteins, amino acids, healing agents, solvents, humectants, emollients, buffers, pH adjusters, chelating agents, and abrasives.
  • a preferred embodiment includes a pearlizing agent.
  • Another subject of the present invention is a process for stabilizing personal cleansing compositions containing at least one active agent, by including therein specific ethoxylated solubilizing agent(s).
  • PEG ethers of fatty alcohols are included in cleansing compositions comprising at least one fragrance.
  • Example 1 (Comparative) The following composition was made using no solubilizer for the active agent, in this case a fragrance.
  • a first premix of sodium hydroxide and water was prepared by mixing the two ingredients with a magnetic stir bar at 25°C until uniform.
  • a second premix was prepared by mixing polyquaternium-7 and water together at 25°C using a magnetic stir bar.
  • a third premix of fragrance, corn oil and BHT was prepared at 35°-40°C using a magnetic stir bar.
  • the viscosity of the composition was measured 24 hours after manufacture using a Brookfield RVT using spindle #5 rotating at 20 rpm for 1 minute at 25°C.
  • the viscosity measurements are shown below in Table 1.
  • the initial viscosity of 15450 centipoise (cps) dropped to 7650 cps after 2 weeks at 45°C. It remained fairly constant after that with a reading of 8750 cps after 8 weeks at 45°C. Thus, when no solubilizer is used, the viscosity drops about 50% in two weeks and remains at about that level.
  • the freeze-thaw process was carried out by placing the composition in a chamber that cycled between a temperature of -10°C and a temperature of 25°C. The composition was maintained at each temperature for about 12 hours, with less than 1 hour transition between the two temperatures. Thus, one cycle was 24 hours in length. After one cycle the viscosity dropped from the initial 15450 cps to 7100 cps, after 6 cycles the viscosity was 6100 cps. Table 2
  • the viscosity reduction is about 55%.
  • Example 3 (Comparative)
  • Example 2 The product in this example, and in the subsequent examples, was made in the same manner as Example 2.
  • the product in this Example 3 was made with 4% Polysorbate-20, a polyoxyethylene sorbitan laurate ester used as a solubilizer to replace the 4% PPG-26 Buteth-26 PEG-40 Hydrogenated castor oil.
  • the viscosity was too low, i.e. less than 5000 cps, and the product was deemed aesthetically unacceptable to achieve the objectives of the present invention.
  • the product in this example was made by replacing the PPG-26 Buteth-26 PEG-40 hydrogenated castor oil of Example 2 with STEARETH-20.
  • the viscosity was measured on a Brookfield RVT viscometer using spindle #6 under the same conditions as those in Example 1.
  • the viscosity measurements are shown below in Table 3. This initial viscosity of 7160 cps dropped only to 5820 cps (a 18.7% drop) after 2 weeks at 45°C.
  • the viscosity showed a slight improvement over time with a reading of 6740 cps (a 5.9% reduction in viscosity) after 8 weeks at 45°C.
  • the freeze-thaw stability measurements are shown below in Table 4.
  • the freeze- thaw stability was also improved showing a reduction of the viscosity to 6360 cps (11.2%) reduction after 1 cycle and a viscosity of 7120 cps (a reduction of 0.6%) after 6 cycles.
  • the composition comprising STEARETH-20 exhibited an acceptable initial viscosity and a relatively constant viscosity profile, whereas the composition containing the PPG-26 Buteth-26 PEG-40 hydrogenated castor oil had an initial viscosity that was too low.
  • Table 1 Table 1
  • Example 5 The product in this example was made in the same manner as in Example 4 by replacing the STEARETH-20 with CETETH-20.
  • the composition of Example 5 exhibited an initial viscosity comparable to the composition containing STEARETH- 20. Although stability studies were not carried out, the result would be expected to be similar to those of Example 4.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

L'invention concerne des compositions de nettoyage stables, contenant un agent de stabilisation choisi parmi des agents de solubilisation éthoxylés, un agent réactif, et un tensioactif, par exemple un parfum, et un procédé de stabilisation de ces compositions.
PCT/IB1999/001423 1998-08-14 1999-08-12 Compositions de nettoyage stables contenant des agents reactifs Ceased WO2000009083A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002338586A CA2338586A1 (fr) 1998-08-14 1999-08-12 Compositions de nettoyage stables contenant des agents reactifs
EP99935008A EP1105091A1 (fr) 1998-08-14 1999-08-12 Compositions de nettoyage stables contenant des agents reactifs
AU50612/99A AU5061299A (en) 1998-08-14 1999-08-12 Stable cleansing compositions containing active agents
JP2000564586A JP2002522466A (ja) 1998-08-14 1999-08-12 作用剤を含有する安定な洗浄用組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9664398P 1998-08-14 1998-08-14
US60/096,643 1998-08-14

Publications (1)

Publication Number Publication Date
WO2000009083A1 true WO2000009083A1 (fr) 2000-02-24

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ID=22258366

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1999/001423 Ceased WO2000009083A1 (fr) 1998-08-14 1999-08-12 Compositions de nettoyage stables contenant des agents reactifs

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EP (1) EP1105091A1 (fr)
JP (1) JP2002522466A (fr)
AU (1) AU5061299A (fr)
CA (1) CA2338586A1 (fr)
WO (1) WO2000009083A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111448301A (zh) * 2017-12-14 2020-07-24 高露洁-棕榄公司 透明织物护理组合物

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0800788D0 (en) * 2008-01-16 2008-02-27 Glaxo Group Ltd Niovel formulation
JP5930953B2 (ja) * 2011-12-14 2016-06-08 花王株式会社 抗菌剤組成物の製造方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753747A (en) * 1987-05-12 1988-06-28 Colgate-Palmolive Co. Process of neutralizing mono-carboxylic acid
WO1991018587A1 (fr) * 1990-05-30 1991-12-12 The Procter & Gamble Company Compositions liquides anti-transpiration
EP0466237A1 (fr) * 1990-07-11 1992-01-15 Quest International B.V. Systèmes d'émulsion stabilisés
EP0658618A2 (fr) * 1993-12-17 1995-06-21 INTERNATIONAL FLAVORS & FRAGRANCES INC. Utilisation des agents tensioactifs spéciaux pour contrôler la viscosité des produits adoucissants pour le linge

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753747A (en) * 1987-05-12 1988-06-28 Colgate-Palmolive Co. Process of neutralizing mono-carboxylic acid
WO1991018587A1 (fr) * 1990-05-30 1991-12-12 The Procter & Gamble Company Compositions liquides anti-transpiration
EP0466237A1 (fr) * 1990-07-11 1992-01-15 Quest International B.V. Systèmes d'émulsion stabilisés
EP0658618A2 (fr) * 1993-12-17 1995-06-21 INTERNATIONAL FLAVORS & FRAGRANCES INC. Utilisation des agents tensioactifs spéciaux pour contrôler la viscosité des produits adoucissants pour le linge

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Y. TOKUOKA: "Solubilization of some synthetic perfumes by anionic-nonionic mixed surfactant systems.", LANGMUIR, vol. 11, no. 3, 1995, pages 725-729, XP002116818 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111448301A (zh) * 2017-12-14 2020-07-24 高露洁-棕榄公司 透明织物护理组合物

Also Published As

Publication number Publication date
EP1105091A1 (fr) 2001-06-13
CA2338586A1 (fr) 2000-02-24
JP2002522466A (ja) 2002-07-23
AU5061299A (en) 2000-03-06

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