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WO2000006727A3 - Human epidermal proteins hepi-1 to hepi-6 - Google Patents

Human epidermal proteins hepi-1 to hepi-6 Download PDF

Info

Publication number
WO2000006727A3
WO2000006727A3 PCT/US1999/017107 US9917107W WO0006727A3 WO 2000006727 A3 WO2000006727 A3 WO 2000006727A3 US 9917107 W US9917107 W US 9917107W WO 0006727 A3 WO0006727 A3 WO 0006727A3
Authority
WO
WIPO (PCT)
Prior art keywords
hepi
human epidermal
epidermal proteins
provides
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/017107
Other languages
French (fr)
Other versions
WO2000006727A2 (en
Inventor
Y Tom Tang
Preeti Lal
Neil C Corley
Karl J Guegler
Chandra Patterson
Mariah R Baughn
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Priority to CA002335228A priority Critical patent/CA2335228A1/en
Priority to EP99938848A priority patent/EP1100905A2/en
Priority to JP2000562509A priority patent/JP2003520564A/en
Priority to AU53243/99A priority patent/AU5324399A/en
Publication of WO2000006727A2 publication Critical patent/WO2000006727A2/en
Publication of WO2000006727A3 publication Critical patent/WO2000006727A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides human epidermal proteins (HEPI) and polynucleotides which identify and encode HEPI. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HEPI.
PCT/US1999/017107 1998-07-28 1999-07-27 Human epidermal proteins hepi-1 to hepi-6 Ceased WO2000006727A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002335228A CA2335228A1 (en) 1998-07-28 1999-07-27 Human epidermal proteins hepi-1 to hepi-6
EP99938848A EP1100905A2 (en) 1998-07-28 1999-07-27 Human epidermal proteins hepi-1 to hepi-6
JP2000562509A JP2003520564A (en) 1998-07-28 1999-07-27 Human epidermal proteins HEPI-1 to HEPI-6
AU53243/99A AU5324399A (en) 1998-07-28 1999-07-27 Human epidermal proteins hepi-1 to hepi-6

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12353198A 1998-07-28 1998-07-28
US60/155,203 1998-07-28
US20681798A 1998-12-07 1998-12-07
US60/155,254 1998-12-07

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/883,805 Division US20050048612A1 (en) 1998-07-28 2004-07-06 Human epidermal proteins HEP1-1 to HEP1-6

Publications (2)

Publication Number Publication Date
WO2000006727A2 WO2000006727A2 (en) 2000-02-10
WO2000006727A3 true WO2000006727A3 (en) 2000-05-04

Family

ID=26821651

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017107 Ceased WO2000006727A2 (en) 1998-07-28 1999-07-27 Human epidermal proteins hepi-1 to hepi-6

Country Status (4)

Country Link
EP (1) EP1100905A2 (en)
AU (1) AU5324399A (en)
CA (1) CA2335228A1 (en)
WO (1) WO2000006727A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030211065A1 (en) * 2001-12-07 2003-11-13 Elon Pras Methods and compositions for diagnosing and treating hypotrichosis simplex
EP2076193A4 (en) 2006-10-18 2010-02-03 Minnow Medical Inc Tuned rf energy and electrical tissue characterization for selective treatment of target tissues

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002121992, Database accession no. AA059561 *
R;ZHOU, Y.; CHAPLIN, D.D.: "Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., vol. 90, 1993, NATIONAL ACADEMY OF SCIENCE. WASHINGTON., US, pages 9470 - 9474, XP002049396, ISSN: 0027-8424 *
SIMON M., MONTEZIN M., GUERRIN M., DURIEUX J.-J., SERRE G.: "Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes", J. BIOL. CHEM., vol. 272, no. 50, 12 December 1997 (1997-12-12), Baltimore USA, pages 31770 - 31776, XP002075788 *
ZHAO X.P., ELDER J.T.: "Positional cloning of novel skin-specific genes from the human epidermal differentiation complex.", GENOMICS 45:250-258(1997)., XP000852660 *

Also Published As

Publication number Publication date
CA2335228A1 (en) 2000-02-10
EP1100905A2 (en) 2001-05-23
AU5324399A (en) 2000-02-21
WO2000006727A2 (en) 2000-02-10

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