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WO2000078933A3 - Neue calpaine und deren verwendung - Google Patents

Neue calpaine und deren verwendung Download PDF

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Publication number
WO2000078933A3
WO2000078933A3 PCT/EP2000/005261 EP0005261W WO0078933A3 WO 2000078933 A3 WO2000078933 A3 WO 2000078933A3 EP 0005261 W EP0005261 W EP 0005261W WO 0078933 A3 WO0078933 A3 WO 0078933A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel
calpains
capn11
synthesis
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/005261
Other languages
English (en)
French (fr)
Other versions
WO2000078933A2 (de
Inventor
Neil T Dear
Thomas Boehm
Achim Moeller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU59706/00A priority Critical patent/AU5970600A/en
Priority to JP2001505676A priority patent/JP2003503023A/ja
Priority to BR0011721-8A priority patent/BR0011721A/pt
Priority to MXPA01012937A priority patent/MXPA01012937A/es
Priority to SK1826-2001A priority patent/SK18262001A3/sk
Priority to CA002375477A priority patent/CA2375477A1/en
Priority to IL14694000A priority patent/IL146940A0/xx
Priority to KR1020017016244A priority patent/KR20020011140A/ko
Application filed by BASF SE filed Critical BASF SE
Priority to EP00945716A priority patent/EP1185673A2/de
Publication of WO2000078933A2 publication Critical patent/WO2000078933A2/de
Publication of WO2000078933A3 publication Critical patent/WO2000078933A3/de
Priority to NO20015922A priority patent/NO20015922L/no
Priority to BG106186A priority patent/BG106186A/bg
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Die Erfindung betrifft ein neues Säugetier-Calpain CAPN11, seine Synthese sowie seine Verwendung.
PCT/EP2000/005261 1999-06-18 2000-06-07 Neue calpaine und deren verwendung Ceased WO2000078933A2 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IL14694000A IL146940A0 (en) 1999-06-18 2000-06-07 Novel calpains and their use
BR0011721-8A BR0011721A (pt) 1999-06-18 2000-06-07 Polipeptìdeo, sequência de polinucleotìdeos, uso de um polipeptìdeo, processo para identificar compostos que inibem a atividade enzimática de um polipeptìdeo, e, uso de compostos
MXPA01012937A MXPA01012937A (es) 1999-06-18 2000-06-07 Calpainas novedosas y su uso.
SK1826-2001A SK18262001A3 (sk) 1999-06-18 2000-06-07 Kalpaíny a ich použitie
CA002375477A CA2375477A1 (en) 1999-06-18 2000-06-07 Novel calpains and their use
KR1020017016244A KR20020011140A (ko) 1999-06-18 2000-06-07 신규 칼파인 및 그의 용도
EP00945716A EP1185673A2 (de) 1999-06-18 2000-06-07 Neue calpaine und deren verwendung
AU59706/00A AU5970600A (en) 1999-06-18 2000-06-07 Novel calpains and their use
JP2001505676A JP2003503023A (ja) 1999-06-18 2000-06-07 新規カルパインおよびその使用
NO20015922A NO20015922L (no) 1999-06-18 2001-12-04 Nye calpainer og anvendelse derav
BG106186A BG106186A (bg) 1999-06-18 2001-12-06 Нови калпаини и използването им

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19928021A DE19928021A1 (de) 1999-06-18 1999-06-18 Neue Calpaine und deren Verwendung
DE19928021.5 1999-06-18

Publications (2)

Publication Number Publication Date
WO2000078933A2 WO2000078933A2 (de) 2000-12-28
WO2000078933A3 true WO2000078933A3 (de) 2001-07-26

Family

ID=7911777

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/005261 Ceased WO2000078933A2 (de) 1999-06-18 2000-06-07 Neue calpaine und deren verwendung

Country Status (18)

Country Link
EP (1) EP1185673A2 (de)
JP (1) JP2003503023A (de)
KR (1) KR20020011140A (de)
CN (1) CN1373808A (de)
AR (1) AR024573A1 (de)
AU (1) AU5970600A (de)
BG (1) BG106186A (de)
BR (1) BR0011721A (de)
CA (1) CA2375477A1 (de)
DE (1) DE19928021A1 (de)
HU (1) HUP0201800A2 (de)
IL (1) IL146940A0 (de)
MX (1) MXPA01012937A (de)
NO (1) NO20015922L (de)
PL (1) PL353004A1 (de)
SK (1) SK18262001A3 (de)
TR (1) TR200103662T2 (de)
WO (1) WO2000078933A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7101700A (en) * 1999-09-02 2001-03-26 Lexicon Genetics Incorporated Human calcium dependent proteases and polynucleotides encoding the same
CN102939126B (zh) 2010-04-30 2015-09-16 雅培心脏血管系统股份有限公司 呈现迅速膨胀和收缩的改进型球囊导管

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737105A1 (de) * 1997-08-26 1999-03-04 Basf Ag Neue gewebsspezifische Calpaine, ihre Herstellung und Verwendung
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737105A1 (de) * 1997-08-26 1999-03-04 Basf Ag Neue gewebsspezifische Calpaine, ihre Herstellung und Verwendung
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEAR T NEIL ET AL: "CAPN11: A calpain with high mRNA levels in testis and located on chromosome 6.", GENOMICS, vol. 59, no. 2, 15 July 1999 (1999-07-15), pages 243 - 247, XP002159274, ISSN: 0888-7543 *
ZHANG WENLI ET AL: "The major calpain isozymes are long-lived proteins. Design of an antisense strategy for calpain depletion in cultured cells.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 31, 1996, pages 18825 - 18830, XP002159273, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
BG106186A (bg) 2002-12-29
AU5970600A (en) 2001-01-09
DE19928021A1 (de) 2000-12-21
PL353004A1 (en) 2003-09-22
TR200103662T2 (tr) 2002-05-21
WO2000078933A2 (de) 2000-12-28
MXPA01012937A (es) 2002-07-30
EP1185673A2 (de) 2002-03-13
NO20015922L (no) 2002-02-12
JP2003503023A (ja) 2003-01-28
CN1373808A (zh) 2002-10-09
CA2375477A1 (en) 2000-12-28
IL146940A0 (en) 2002-08-14
AR024573A1 (es) 2002-10-16
KR20020011140A (ko) 2002-02-07
HUP0201800A2 (en) 2002-09-28
BR0011721A (pt) 2002-03-05
NO20015922D0 (no) 2001-12-04
SK18262001A3 (sk) 2002-09-10

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