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WO2000070096A3 - Methodes de depistage de pathologies colo-rectales - Google Patents

Methodes de depistage de pathologies colo-rectales Download PDF

Info

Publication number
WO2000070096A3
WO2000070096A3 PCT/US2000/013655 US0013655W WO0070096A3 WO 2000070096 A3 WO2000070096 A3 WO 2000070096A3 US 0013655 W US0013655 W US 0013655W WO 0070096 A3 WO0070096 A3 WO 0070096A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
bat
locus
mutation
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/013655
Other languages
English (en)
Other versions
WO2000070096A2 (fr
Inventor
Steven Laken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exact Sciences Corp
Original Assignee
Exact Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exact Laboratories Inc filed Critical Exact Laboratories Inc
Priority to JP2000618501A priority Critical patent/JP2002543855A/ja
Priority to CA002372667A priority patent/CA2372667A1/fr
Priority to AU50274/00A priority patent/AU767833B2/en
Priority to EP00932573A priority patent/EP1179092A2/fr
Publication of WO2000070096A2 publication Critical patent/WO2000070096A2/fr
Publication of WO2000070096A3 publication Critical patent/WO2000070096A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des méthodes faisant appel à des dosages de marqueurs indiquant un cancer, un état précancéreux ou d'autre pathologies ou lésions. Ces dosages sont pratiqués sur des échantillons hétérogènes prélevés sur les patients au moyen de méthodes non effractives ou très peu effractives. Ces dosages peuvent être pratiqués isolément ou combinés avec d'autres techniques de dépistage de maladies.
PCT/US2000/013655 1999-01-10 2000-05-18 Methodes de depistage de pathologies colo-rectales Ceased WO2000070096A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000618501A JP2002543855A (ja) 1999-01-10 2000-05-18 Ｂａｔ−２６遺伝子座における変異を検出するアッセイを実施することによって結腸直腸疾患を検出する方法
CA002372667A CA2372667A1 (fr) 1999-01-10 2000-05-18 Methodes de depistage de pathologies colo-rectales
AU50274/00A AU767833B2 (en) 1999-01-10 2000-05-18 Methods of detecting colorectal disease
EP00932573A EP1179092A2 (fr) 1999-01-10 2000-05-18 Methodes de depistage de pathologies colo-rectales

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13471199P 1999-01-10 1999-01-10
US60/134,711 1999-05-18
US46867099A 1999-12-21 1999-12-21
US09/468,670 1999-12-21

Publications (2)

Publication Number Publication Date
WO2000070096A2 WO2000070096A2 (fr) 2000-11-23
WO2000070096A3 true WO2000070096A3 (fr) 2001-06-14

Family

ID=26832603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/013655 Ceased WO2000070096A2 (fr) 1999-01-10 2000-05-18 Methodes de depistage de pathologies colo-rectales

Country Status (5)

Country Link
EP (1) EP1179092A2 (fr)
JP (1) JP2002543855A (fr)
AU (1) AU767833B2 (fr)
CA (1) CA2372667A1 (fr)
WO (1) WO2000070096A2 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6919174B1 (en) 1999-12-07 2005-07-19 Exact Sciences Corporation Methods for disease detection
US6964846B1 (en) 1999-04-09 2005-11-15 Exact Sciences Corporation Methods for detecting nucleic acids indicative of cancer
US7368233B2 (en) 1999-12-07 2008-05-06 Exact Sciences Corporation Methods of screening for lung neoplasm based on stool samples containing a nucleic acid marker indicative of a neoplasm
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818404B2 (en) 1997-10-23 2004-11-16 Exact Sciences Corporation Methods for detecting hypermethylated nucleic acid in heterogeneous biological samples
US6280947B1 (en) * 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US6503718B2 (en) * 1999-01-10 2003-01-07 Exact Sciences Corporation Methods for detecting mutations using primer extension for detecting disease
US20020004206A1 (en) * 1999-04-09 2002-01-10 Berger Barry M. Methods of screening for disease
US6911308B2 (en) 2001-01-05 2005-06-28 Exact Sciences Corporation Methods for detecting, grading or monitoring an H. pylori infection
US7691571B2 (en) 2001-01-31 2010-04-06 Mayo Foundation For Medical Education And Research Detection of bordetella
WO2002061390A2 (fr) 2001-01-31 2002-08-08 Mayo Foundation For Medical Education And Research Detection du virus de l'herpes simplex
US20030180765A1 (en) * 2002-02-01 2003-09-25 The Johns Hopkins University Digital amplification for detection of mismatch repair deficient tumor cells
US20030215954A1 (en) * 2002-05-17 2003-11-20 Cockerill Franklin R. Nucleic acid recovery reagents and methods
US7074598B2 (en) 2002-09-25 2006-07-11 Mayo Foundation For Medical Education And Research Detection of vancomycin-resistant enterococcus spp.
US7365176B2 (en) 2002-09-26 2008-04-29 Mayo Foundation For Medical Education And Research Detection of Epstein-Barr virus
US7427475B2 (en) 2003-11-18 2008-09-23 Mayo Foundation For Medical Education And Research Detection of group B streptococcus
US20050282196A1 (en) * 2004-04-30 2005-12-22 Jose Costa Methods and compositions for cancer diagnosis
WO2007044071A2 (fr) 2005-04-21 2007-04-19 Exact Sciences Corporation Analyse d'echantillons d'acide nucleique heterogenes
US20140234854A1 (en) * 2012-11-30 2014-08-21 Applied Proteomics, Inc. Method for evaluation of presence of or risk of colon tumors
US9689874B2 (en) 2015-04-10 2017-06-27 Applied Proteomics, Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US20220228221A1 (en) * 2019-06-17 2022-07-21 The Board Of Trustees Of The Leland Stanford Junior University Diagnostics and Treatments Based Upon Molecular Characterization of Colorectal Cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANDREAS BRAUN ET AL: "Improved Analysis of Microsaellites Using Mass spectrometry", GENOMICS, vol. 46, 1997, pages 18 - 23, XP002162453 *
GISMONDI VIVIANA ET AL: "Characterization of 19 novel and six recurring APC mutations in Italian adenomatous polyposis patients, using two different mutation detection techniques.", HUMAN MUTATION, vol. 9, no. 4, 1997, pages 370 - 373, XP002162567, ISSN: 1059-7794 *
HOANG JEAN-MARC ET AL: "BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.", CANCER RESEARCH, vol. 57, no. 2, 1997, pages 300 - 303, XP002162454, ISSN: 0008-5472 *
LOTHE RAGNHILD A ET AL: "The APC gene I1307K variant is rare in Norwegian patients with familial and sporadic colorectal or breast cancer.", CANCER RESEARCH, vol. 58, no. 14, 15 July 1998 (1998-07-15), pages 2923 - 2924, XP002162568, ISSN: 0008-5472 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964846B1 (en) 1999-04-09 2005-11-15 Exact Sciences Corporation Methods for detecting nucleic acids indicative of cancer
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6919174B1 (en) 1999-12-07 2005-07-19 Exact Sciences Corporation Methods for disease detection
US7368233B2 (en) 1999-12-07 2008-05-06 Exact Sciences Corporation Methods of screening for lung neoplasm based on stool samples containing a nucleic acid marker indicative of a neoplasm
US7981612B2 (en) 1999-12-07 2011-07-19 Mayo Foundation For Medical Education And Research Methods of screening for supracolonic neoplasms based on stool samples containing a nucleic acid marker indicative of a neoplasm
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence

Also Published As

Publication number Publication date
AU767833B2 (en) 2003-11-27
EP1179092A2 (fr) 2002-02-13
JP2002543855A (ja) 2002-12-24
CA2372667A1 (fr) 2000-11-23
WO2000070096A2 (fr) 2000-11-23
AU5027400A (en) 2000-12-05

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