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WO2000069843A3 - Cycloalkyl substituted 3-urea-benzofurane-and -pyridofurane-derivatives - Google Patents

Cycloalkyl substituted 3-urea-benzofurane-and -pyridofurane-derivatives Download PDF

Info

Publication number
WO2000069843A3
WO2000069843A3 PCT/EP2000/004012 EP0004012W WO0069843A3 WO 2000069843 A3 WO2000069843 A3 WO 2000069843A3 EP 0004012 W EP0004012 W EP 0004012W WO 0069843 A3 WO0069843 A3 WO 0069843A3
Authority
WO
WIPO (PCT)
Prior art keywords
pyridofurane
benzofurane
urea
derivatives
cycloalkyl substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/004012
Other languages
French (fr)
Other versions
WO2000069843A2 (en
Inventor
Graham Sturton
Mary F Fitzgerald
Barbara A Briggs
Arnel Concepcion
William Bullock
Gabriele Braeunlich
Mazen Es-Sayed
Ruediger Fischer
Burkhard Fugmann
Rolf Henning
Stephan Schneider
Michael Sperzel
Karl-Heinz Schlemmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU47552/00A priority Critical patent/AU4755200A/en
Publication of WO2000069843A2 publication Critical patent/WO2000069843A2/en
Publication of WO2000069843A3 publication Critical patent/WO2000069843A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cycloalkyl substituted 3-urea-benzofurane- and -pyridofurane-derivatives of general formula (I) for the treatment of inflammatory processes.
PCT/EP2000/004012 1999-05-17 2000-05-04 Cycloalkyl substituted 3-urea-benzofurane-and -pyridofurane-derivatives Ceased WO2000069843A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU47552/00A AU4755200A (en) 1999-05-17 2000-05-04 Cycloalkyl substituted 3-urea-benzofurane-and -pyridofurane-derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9911458.9 1999-05-17
GB9911458A GB2350112A (en) 1999-05-17 1999-05-17 Pharmaceutically active cycloalkyl ketones

Publications (2)

Publication Number Publication Date
WO2000069843A2 WO2000069843A2 (en) 2000-11-23
WO2000069843A3 true WO2000069843A3 (en) 2001-02-15

Family

ID=10853625

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/004012 Ceased WO2000069843A2 (en) 1999-05-17 2000-05-04 Cycloalkyl substituted 3-urea-benzofurane-and -pyridofurane-derivatives

Country Status (3)

Country Link
AU (1) AU4755200A (en)
GB (1) GB2350112A (en)
WO (1) WO2000069843A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1478639A1 (en) 2002-02-22 2004-11-24 Bayer Pharmaceuticals Corporation Fused tricyclic heterocycles useful for treating hyper-proliferative disorders
US7144885B2 (en) 2002-02-22 2006-12-05 Bayer Pharmaceuticals Corporation Fused tricyclic heterocycles useful for treating hyper-proliferative disorders
US7601725B2 (en) 2004-07-16 2009-10-13 Sunesis Pharmaceuticals, Inc. Thienopyrimidines useful as Aurora kinase inhibitors
DE102005013621A1 (en) * 2005-03-24 2006-09-28 Curacyte Discovery Gmbh Substituted 2-aryl (hetaryl) -5-aminothieno [2,3-d] pyrimidine-6-carboxylic acid amides, process for their preparation and use as pharmaceuticals

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0146243A1 (en) * 1983-10-31 1985-06-26 Merck Frosst Canada Inc. Lipoxygenase inhibitors
EP0731099A1 (en) * 1995-03-06 1996-09-11 Bayer Ag N-(3-benzofuranyl)urea-derivatives
EP0779291A1 (en) * 1995-12-11 1997-06-18 Bayer Ag Heterocyclylcarbonyl substituted benzofuranyl-ureas
WO1998002440A1 (en) * 1996-07-12 1998-01-22 Bayer Aktiengesellschaft 3-ureido-pyridofurans and -pyridothiophenes for the treatment of inflammatory processes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277878B1 (en) * 1998-09-07 2001-08-21 Pfizer Inc Substituted indole compounds as anti-inflammatory and analgesic agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0146243A1 (en) * 1983-10-31 1985-06-26 Merck Frosst Canada Inc. Lipoxygenase inhibitors
EP0731099A1 (en) * 1995-03-06 1996-09-11 Bayer Ag N-(3-benzofuranyl)urea-derivatives
EP0779291A1 (en) * 1995-12-11 1997-06-18 Bayer Ag Heterocyclylcarbonyl substituted benzofuranyl-ureas
WO1998002440A1 (en) * 1996-07-12 1998-01-22 Bayer Aktiengesellschaft 3-ureido-pyridofurans and -pyridothiophenes for the treatment of inflammatory processes

Also Published As

Publication number Publication date
GB9911458D0 (en) 1999-07-14
WO2000069843A2 (en) 2000-11-23
GB2350112A (en) 2000-11-22
AU4755200A (en) 2000-12-05

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