WO2000066050A1 - Implant lateral pharynge - Google Patents
Implant lateral pharynge Download PDFInfo
- Publication number
- WO2000066050A1 WO2000066050A1 PCT/EP2000/003607 EP0003607W WO0066050A1 WO 2000066050 A1 WO2000066050 A1 WO 2000066050A1 EP 0003607 W EP0003607 W EP 0003607W WO 0066050 A1 WO0066050 A1 WO 0066050A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- implant
- implanted
- throat
- tongue
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
- A61F5/56—Devices for preventing snoring
- A61F5/566—Intra-oral devices
Definitions
- the invention relates to a pharyngeal side implant.
- OSAS obstructive sleep apnea syndrome
- REM rapid eye movement
- the OSAS is in need of treatment because cardiac muscle damage, coronary artery disease, cerebral vascular disease with an increase in stroke and cerebral reduction as well as high blood pressure crises and a large number of hormonal disorders can occur due to the regular oxygen desaturation of the blood during sleep.
- the frequent lack of deep sleep phases, the disturbance of REM sleep phases and the frequent awakening lead to listlessness, daytime tiredness and a tendency to fall asleep during the day, which can lead to accidents when operating machines or driving a car.
- oral prostheses are known, which before to be used for falling asleep in the throat and have the purpose of pushing the base of the tongue forward.
- oral prostheses are only promising if the OSAS is mild and are also complicated because of the complexity
- Surgical therapeutic measures are also known for the treatment of OSAS, which essentially consist in improving the air passage in the nasal and nasopharynx area. Attempts have even been made to advance the lower and upper jaw or a sawn-out quadrilateral of the lower jaw in the chin area with attached tongue muscles, in order to improve the air passage. This is a major surgical procedure, which is a considerable burden for the patient and, moreover, rarely delivers acceptable results since, like the surgical therapy measures described above, it only treats indirectly because the relapse of the patient
- Tongue body and its application to the back of the throat and the associated closure of the airway is not causally avoided.
- the unpublished German patent application with the official file number 197 56 956 describes an implant for implantation in a tongue, which has a fastening part for fastening to the hyoid bone or to the tissue located to the side of the tongue, as well as a support part which extends from the fastening part in extends the area of the base of the tongue and essentially transverse to the direction of the tongue.
- the invention has for its object to provide a pharyngeal implant through which the OSAS is effectively avoided or reduced and impairments of the patient, such as difficulty swallowing and disturbances during sleep, are largely avoided, in particular in the event that the tongue-type implant according to German patent application 197 56 956 is not sufficient for the treatment of OSAS.
- the basic idea of this teaching is to create a pharyngeal side implant that can be implanted such that one end of the implant is arranged on the cervical vertebra side and the other end on the tongue side edge side.
- the pharyngeal side implant according to the invention can advantageously be used if the supporting effect of the above-mentioned basic tongue implant is insufficient and a basic tongue implant reinforcement or a changing basic tongue implant should not be carried out for various reasons.
- a possible reason for this would be that too much impairment of the basic tongue mobility is feared or that the basic tongue implant has healed up so well that further surgical manipulation in the area of the implant leads to the fear of excessive scarring or a different deterioration in the result of the operation.
- the main effect of the pharyngeal side implant according to the invention would be to support the edge of the tongue; a side effect would be the support of the lateral throat tissue.
- the pharyngeal side implant according to the invention can also be used advantageously if an essential further cause of the OSAS is seen in the collapse of the lateral throat walls.
- the main effect of the pharyngeal side implant would be to support the lateral pharynx tissue, with the side effect of supporting the edge of the tongue.
- the lateral edge of the tongue can be supported more than if only a basic tongue implant is used, without the entire supporting force being transmitted across the base of the tongue, ie the tongue remains more mobile than with the sole basic tongue support and the swallowing process is less is impaired, since the support force is better distributed in the entire throat cross-section and / or over part of the length of the throat.
- the implant parts of the implants are advantageously curved, such that in the implanted state the convex side faces the inside of the throat or the throat mucosa. As a result, particularly good support effects are exerted on the lateral edge of the tongue and / or the lateral throat tissue.
- FIG. 1 shows a cross section through the facial skull at the level of the back of the tongue with two implant parts of an inserted implant according to the invention
- 2 shows an oral cavity from the front with the palate and cheek mucosa removed on the left side and inserted two-part implants
- FIG. 3 shows a lateral sagittal section through the lower facial skull (the mouth and nose area opened from the right by removing the right lower and upper jaw) with two implanted Implant parts of implants according to the invention.
- FIGS. 1 to 3 The anatomical parts shown schematically in FIGS. 1 to 3 are designated with reference numerals as follows:
- FIG. 1 shows the arrangement of a first implant 1 with a left implant part 46 and a right implant part 52.
- the implant parts 46, 52 each have a front end 50, 56 on the tongue edge and a rear end 48, 54 on the cervical vertebra side.
- the implant 48, 54 on the cervical vertebra side can be connected to the spine 38, for example by means of a screw; however, it can also be arranged at a distance from the spine and end in the tissue adjacent to the spine, as a result of which a greater or lesser degree of mobility is maintained in all directions for this implant end, the mobility in the direction of the spine being limited by the latter itself.
- the mobility in the other directions is mainly limited by the elasticity of the tissue located between the end of the implant and the spine, but also by restoring forces of the remaining tissue adjacent to the implant.
- the front end 50, 56 of the implant parts on the side of the tongue side can be arranged in the region of the side of the tongue side or rest against the side of the tongue side or be implanted in the side of the tongue.
- the two implant parts 46, 52 are preferably implanted through a slot in the lateral tongue back 4 and each extend in a curved shape behind the tonsil to the cervical vertebrae. per 38.
- the bent implant parts are arranged so that in the implanted state the convex side of the implant parts faces the inside of the throat or the pharynx mucosa.
- the implant parts 46, 52 of the implant 1 can thus perform two functions, namely supporting the lateral tongue areas against falling back and supporting the throat side wall against collapsing towards the middle of the throat.
- FIG. 2 which shows the oral cavity from the front with the palate and cheek mucosa removed on the left, shows on the one hand the arrangement of the implant 1 described in connection with FIG. 1 and the arrangement of a further implant 1 '.
- the further pharyngeal side implant 1 ' likewise has two implant parts, a left implant part 60 and a right implant part 61. These implant parts 60, 61 are preferably implanted at an angle of approximately 45 ° to the implant parts 46, 52 and are used in particular to support the side wall of the throat.
- implant parts 60, 61 run obliquely from the front up through the front lateral soft palate to the rear below the lateral spine and have no contact with the tongue. They each have a front end of the soft palate or throat wall 72, 74 and a rear end of the cervical vertebra 76, 78 and, like the implant parts 46, 52 of the implant 1, are curved such that in the implanted state the convex side faces the inside of the throat or the pharynx mucosa.
- the use of the implant 1 ' that is to say the implant parts 60 and 61, has advantages in particular if the throat above the back of the tongue, that is to say in the region of the palate arches, collapses during sleep and this region is to be supported.
- the rear end 76, 78 of the implant parts 60, 61 of the implant 1 ' is fastened to or supported on the cervical spine 38 or is fastened or supported in the tissue lying in front of it.
- the front end 72, 74 of the inserted implant parts 60, 61 is attached to or is supported on the tissue located in the vicinity of the lateral hard palate posterior margin 6 and / or the pterygoid bone 70.
- FIG 3 shows the respective right implant parts 52 of the implant 1 and 61 of the implant 1 'according to the invention in the respectively implanted position, the right side face with opening of the right mouth and right nose being shown in the drawing for better illustration is removed.
- the implant parts 46, 52, 60, 61 are essentially strip-shaped, whereby strip-shaped should also be understood to mean a structure that is flat but at different points also of different thicknesses and widths.
- the longitudinal extent of the implant parts is preferably greater than the implant thickness, it being possible for the transverse extent to be variable.
- the implant parts have, at least after the implantation, a shape which is convexly curved with respect to the side wall of the pharynx.
- the implants 1 and 1 ' can be used individually and in combination with one another or individually or together. can be used with a basic tongue implant, especially if it has been proven from the outset that OSAS both causes the tongue to fall back and the side of the throat to collapse. The choice of implants depends on which structures collapse significantly during sleep.
- the lateral pharynx implants according to the invention are preferably very soft in order not to irritate or injure the essential structures such as nerves and vessels. They consist of cultivated, body-own tissue or of plastic or a combination of both materials. Instead of grown, body-own tissue, body-own tissue taken elsewhere can also be used.
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Rehabilitation Therapy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Nursing (AREA)
- Prostheses (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
Abstract
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00920730A EP1175190A1 (fr) | 1999-05-03 | 2000-04-20 | Implant lateral pharynge |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19920114.5 | 1999-05-03 | ||
| DE1999120114 DE19920114A1 (de) | 1999-05-03 | 1999-05-03 | Rachenseitenimplantat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2000066050A1 true WO2000066050A1 (fr) | 2000-11-09 |
Family
ID=7906689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2000/003607 Ceased WO2000066050A1 (fr) | 1999-05-03 | 2000-04-20 | Implant lateral pharynge |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1175190A1 (fr) |
| DE (1) | DE19920114A1 (fr) |
| WO (1) | WO2000066050A1 (fr) |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009542377A (ja) * | 2006-07-06 | 2009-12-03 | クワイエセンス メディカル インコーポレイテッド | 睡眠時無呼吸症処置用の装置及び方法 |
| US7686021B2 (en) * | 2002-02-04 | 2010-03-30 | Medtronic Xomed, Inc. | Pharyngeal tissue stabilization |
| US8186355B2 (en) | 2005-11-09 | 2012-05-29 | Koninklijke Philips Electronics N.V. | Glossoplasty using tissue anchor glossopexy with volumetric tongue reduction |
| US8327854B2 (en) | 2008-05-12 | 2012-12-11 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US8413661B2 (en) | 2008-08-14 | 2013-04-09 | Ethicon, Inc. | Methods and devices for treatment of obstructive sleep apnea |
| US8523760B2 (en) | 2008-01-03 | 2013-09-03 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US8733363B2 (en) | 2010-03-19 | 2014-05-27 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US8776799B2 (en) | 2010-03-19 | 2014-07-15 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US8905033B2 (en) | 2011-09-28 | 2014-12-09 | Ethicon, Inc. | Modular tissue securement systems |
| US8915252B2 (en) | 2008-12-01 | 2014-12-23 | Ethicon, Inc. | Implant systems and methods for treating obstructive sleep apnea |
| US8973582B2 (en) | 2011-11-30 | 2015-03-10 | Ethicon, Inc. | Tongue suspension device and method |
| US9161855B2 (en) | 2011-10-24 | 2015-10-20 | Ethicon, Inc. | Tissue supporting device and method |
| US9173766B2 (en) | 2012-06-01 | 2015-11-03 | Ethicon, Inc. | Systems and methods to treat upper pharyngeal airway of obstructive sleep apnea patients |
| US9326886B2 (en) | 2009-10-29 | 2016-05-03 | Ethicon, Inc. | Fluid filled implants for treating obstructive sleep apnea |
| US9439801B2 (en) | 2012-06-29 | 2016-09-13 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US9510922B2 (en) | 2010-05-21 | 2016-12-06 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US9707122B2 (en) | 2010-07-26 | 2017-07-18 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US9877862B2 (en) | 2009-10-29 | 2018-01-30 | Ethicon, Inc. | Tongue suspension system with hyoid-extender for treating obstructive sleep apnea |
| US9974683B2 (en) | 2009-10-30 | 2018-05-22 | Ethicon, Inc. | Flexible implants having internal volume shifting capabilities for treating obstructive sleep apnea |
| US10470760B2 (en) | 2011-12-08 | 2019-11-12 | Ethicon, Inc. | Modified tissue securement fibers |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6450169B1 (en) | 1999-09-17 | 2002-09-17 | Pi Medical, Inc. | Braided implant for snoring treatment |
| US6250307B1 (en) | 1999-09-17 | 2001-06-26 | Pi Medical, Inc. | Snoring treatment |
| US6431174B1 (en) | 2000-08-10 | 2002-08-13 | Pi Medical, Inc. | Method and apparatus to treat conditions of the naso-pharyngeal area |
| US7017582B2 (en) | 2002-02-04 | 2006-03-28 | Restore Medical Inc. | Stiffening pharyngeal wall treatment |
| US7647931B2 (en) | 2002-12-30 | 2010-01-19 | Quiescence Medical, Inc. | Stent for maintaining patency of a body region |
| US7992566B2 (en) | 2002-12-30 | 2011-08-09 | Quiescence Medical, Inc. | Apparatus and methods for treating sleep apnea |
| US7381222B2 (en) | 2002-12-30 | 2008-06-03 | Quiescence Medical, Inc. | Stent for maintaining patency of a body region |
| USD536792S1 (en) | 2003-09-19 | 2007-02-13 | Restore Medical, Inc. | Implant delivery tool |
| US7237554B2 (en) * | 2003-10-31 | 2007-07-03 | Restore Medical, Inc. | Airway implant |
| US7213599B2 (en) | 2003-10-31 | 2007-05-08 | Restore Medical, Inc. | Airway implant |
| CA2545651A1 (fr) * | 2003-11-20 | 2005-06-09 | Apneon, Inc. | Dispositifs, systemes et procedes permettant de fixer des tissus dans certaines zones corporelles, telles que le conduit pharyngien |
| DE102005000702B4 (de) | 2005-01-04 | 2007-08-23 | Klinikum Der Universität Regensburg | Vorrichtung zur mittigen Implantation in einen Zungenkörper |
| US7337781B2 (en) | 2005-04-15 | 2008-03-04 | Restore Medical, Inc. | Implant for tongue |
| US8517028B2 (en) | 2006-06-23 | 2013-08-27 | Medtronic Xomed, Inc. | Stiffening procedure for sleep apnea |
| US20080078412A1 (en) | 2006-10-03 | 2008-04-03 | Restore Medical, Inc. | Tongue implant |
| US20080078411A1 (en) | 2006-10-03 | 2008-04-03 | Restore Medical, Inc. | Tongue implant for sleep apnea |
| US9265649B2 (en) | 2010-12-13 | 2016-02-23 | Quiescence Medical, Inc. | Apparatus and methods for treating sleep apnea |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU1801414C (ru) * | 1990-08-04 | 1993-03-15 | Московский научно-исследовательский онкологический институт им.П.А.Герцена | Протез черпаловидного хр ща |
| DE19501363A1 (de) * | 1995-01-18 | 1995-09-21 | Hans D Dipl Ing Weitermann | Mechanische Schienung der Atemwege zur Verhinderung des Schnarchens und der Atemstillstände |
| DE19636680C1 (de) * | 1996-09-10 | 1998-04-16 | Ende Mathias Am | Vorrichtung zum Verhindern des Schnarchens |
| WO1999032057A1 (fr) * | 1997-12-20 | 1999-07-01 | Wolfgang Fege | Implant destine a etre implante dans une langue |
-
1999
- 1999-05-03 DE DE1999120114 patent/DE19920114A1/de not_active Withdrawn
-
2000
- 2000-04-20 WO PCT/EP2000/003607 patent/WO2000066050A1/fr not_active Ceased
- 2000-04-20 EP EP00920730A patent/EP1175190A1/fr not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU1801414C (ru) * | 1990-08-04 | 1993-03-15 | Московский научно-исследовательский онкологический институт им.П.А.Герцена | Протез черпаловидного хр ща |
| DE19501363A1 (de) * | 1995-01-18 | 1995-09-21 | Hans D Dipl Ing Weitermann | Mechanische Schienung der Atemwege zur Verhinderung des Schnarchens und der Atemstillstände |
| DE19636680C1 (de) * | 1996-09-10 | 1998-04-16 | Ende Mathias Am | Vorrichtung zum Verhindern des Schnarchens |
| WO1999032057A1 (fr) * | 1997-12-20 | 1999-07-01 | Wolfgang Fege | Implant destine a etre implante dans une langue |
Non-Patent Citations (1)
| Title |
|---|
| SOVIET PATENTS ABSTRACTS Section PQ Week 9422, 20 July 1994 Derwent World Patents Index; Class P32, AN 94-181056, XP002143671 * |
Cited By (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8430900B2 (en) | 2002-02-04 | 2013-04-30 | Medtronic Xomed, Inc. | Pharyngeal wall treatment |
| US7686021B2 (en) * | 2002-02-04 | 2010-03-30 | Medtronic Xomed, Inc. | Pharyngeal tissue stabilization |
| US8424531B2 (en) | 2002-02-04 | 2013-04-23 | Medtronic Xomed, Inc. | Pharyngeal wall treatment |
| US8186355B2 (en) | 2005-11-09 | 2012-05-29 | Koninklijke Philips Electronics N.V. | Glossoplasty using tissue anchor glossopexy with volumetric tongue reduction |
| US9393067B2 (en) | 2005-11-09 | 2016-07-19 | Koninklijke Philips N.V. | Glassoplasty using tissue anchor glossopexy with volumetric tongue reduction |
| JP2009542377A (ja) * | 2006-07-06 | 2009-12-03 | クワイエセンス メディカル インコーポレイテッド | 睡眠時無呼吸症処置用の装置及び方法 |
| US8523760B2 (en) | 2008-01-03 | 2013-09-03 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US8747296B2 (en) | 2008-01-03 | 2014-06-10 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US8991398B2 (en) | 2008-05-12 | 2015-03-31 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US8707960B2 (en) | 2008-05-12 | 2014-04-29 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US8327854B2 (en) | 2008-05-12 | 2012-12-11 | Revent Medical, Inc. | Partially erodable systems for treatment of obstructive sleep apnea |
| US8413661B2 (en) | 2008-08-14 | 2013-04-09 | Ethicon, Inc. | Methods and devices for treatment of obstructive sleep apnea |
| US9144511B2 (en) | 2008-08-14 | 2015-09-29 | Ethicon, Inc. | Methods and devices for treatment of obstructive sleep apnea |
| US8915252B2 (en) | 2008-12-01 | 2014-12-23 | Ethicon, Inc. | Implant systems and methods for treating obstructive sleep apnea |
| US9326886B2 (en) | 2009-10-29 | 2016-05-03 | Ethicon, Inc. | Fluid filled implants for treating obstructive sleep apnea |
| US9877862B2 (en) | 2009-10-29 | 2018-01-30 | Ethicon, Inc. | Tongue suspension system with hyoid-extender for treating obstructive sleep apnea |
| US9974683B2 (en) | 2009-10-30 | 2018-05-22 | Ethicon, Inc. | Flexible implants having internal volume shifting capabilities for treating obstructive sleep apnea |
| US8776799B2 (en) | 2010-03-19 | 2014-07-15 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US9381109B2 (en) | 2010-03-19 | 2016-07-05 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US8733363B2 (en) | 2010-03-19 | 2014-05-27 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US9510922B2 (en) | 2010-05-21 | 2016-12-06 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US9707122B2 (en) | 2010-07-26 | 2017-07-18 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
| US8905033B2 (en) | 2011-09-28 | 2014-12-09 | Ethicon, Inc. | Modular tissue securement systems |
| US9592046B2 (en) | 2011-09-28 | 2017-03-14 | Ethicon, Inc. | Modular tissue securement systems |
| US9161855B2 (en) | 2011-10-24 | 2015-10-20 | Ethicon, Inc. | Tissue supporting device and method |
| US8973582B2 (en) | 2011-11-30 | 2015-03-10 | Ethicon, Inc. | Tongue suspension device and method |
| US10470760B2 (en) | 2011-12-08 | 2019-11-12 | Ethicon, Inc. | Modified tissue securement fibers |
| US9173766B2 (en) | 2012-06-01 | 2015-11-03 | Ethicon, Inc. | Systems and methods to treat upper pharyngeal airway of obstructive sleep apnea patients |
| US9439801B2 (en) | 2012-06-29 | 2016-09-13 | Revent Medical, Inc. | Systems and methods for treatment of sleep apnea |
Also Published As
| Publication number | Publication date |
|---|---|
| DE19920114A1 (de) | 2000-11-09 |
| EP1175190A1 (fr) | 2002-01-30 |
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