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WO2000055349A1 - 3,3'-diceto-trehalose - Google Patents

3,3'-diceto-trehalose Download PDF

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Publication number
WO2000055349A1
WO2000055349A1 PCT/JP2000/001702 JP0001702W WO0055349A1 WO 2000055349 A1 WO2000055349 A1 WO 2000055349A1 JP 0001702 W JP0001702 W JP 0001702W WO 0055349 A1 WO0055349 A1 WO 0055349A1
Authority
WO
WIPO (PCT)
Prior art keywords
trehalose
trehalase
present
diketotrehalose
glucose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2000/001702
Other languages
English (en)
Japanese (ja)
Inventor
Koji Sode
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU31960/00A priority Critical patent/AU3196000A/en
Priority to JP2000605766A priority patent/JP4468592B2/ja
Publication of WO2000055349A1 publication Critical patent/WO2000055349A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04Disaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/12Disaccharides

Definitions

  • FIG. 6 shows the 13 C NMR structural analysis of the compound of the present invention and a comparative compound.
  • FIG. 7 shows the hydrolysis products of the compounds of the present invention.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne un nouveau dérivé du tréhalose représenté par la formule (I). Ce composé peut s'utiliser comme un inhibiteur du tréhalose et un stabilisateur pour les protéines lyophilisables.
PCT/JP2000/001702 1999-03-18 2000-03-21 3,3'-diceto-trehalose Ceased WO2000055349A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU31960/00A AU3196000A (en) 1999-03-18 2000-03-21 3,3'-diketotrehalose
JP2000605766A JP4468592B2 (ja) 1999-03-18 2000-03-21 3,3’−ジケトトレハロース

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11/73568 1999-03-18
JP7356899 1999-03-18

Publications (1)

Publication Number Publication Date
WO2000055349A1 true WO2000055349A1 (fr) 2000-09-21

Family

ID=13522019

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2000/001702 Ceased WO2000055349A1 (fr) 1999-03-18 2000-03-21 3,3'-diceto-trehalose

Country Status (3)

Country Link
JP (1) JP4468592B2 (fr)
AU (1) AU3196000A (fr)
WO (1) WO2000055349A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016521686A (ja) * 2013-05-30 2016-07-25 蘇州科景生物医薬科技有限公司 多機能組成物並びにその作製方法及び使用
WO2016163448A1 (fr) * 2015-04-09 2016-10-13 東洋紡株式会社 Préparation enzymatique destinée à une utilisation dans la mesure du glucose

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ASANO N. ET. AL.: "Preparation of 3-amino-3-deoxy derivaties of Trehalose and sucrose and their activities.", THE JOURNAL OF ANTIBIOTICS, vol. 42, no. 4, 1989, pages 585 - 590, XP002928094 *
LA. TEMESVARI, DA. COTTER: "Trehalase of Dictyostelium discoideum : Inhibition by amino-containing analogs of trehalose and affinity purification.", BIOCHIMIE, vol. 79, 1997, pages 229 - 239, XP002928095 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016521686A (ja) * 2013-05-30 2016-07-25 蘇州科景生物医薬科技有限公司 多機能組成物並びにその作製方法及び使用
US9937198B2 (en) 2013-05-30 2018-04-10 Pinghu Sciscape Bio-Pharmaceutical Technology Co., Ltd. Multi-functional composition and preparation method and application thereof
WO2016163448A1 (fr) * 2015-04-09 2016-10-13 東洋紡株式会社 Préparation enzymatique destinée à une utilisation dans la mesure du glucose
US10913971B2 (en) 2015-04-09 2021-02-09 Toyobo Co., Ltd. Enzyme preparation for use in measurement of glucose

Also Published As

Publication number Publication date
JP4468592B2 (ja) 2010-05-26
AU3196000A (en) 2000-10-04

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