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WO2000050593A8 - Beta-tubulin autoantibody in meniere's disease and other inner ear diseases and a diagnostic method - Google Patents

Beta-tubulin autoantibody in meniere's disease and other inner ear diseases and a diagnostic method

Info

Publication number
WO2000050593A8
WO2000050593A8 PCT/US2000/004795 US0004795W WO0050593A8 WO 2000050593 A8 WO2000050593 A8 WO 2000050593A8 US 0004795 W US0004795 W US 0004795W WO 0050593 A8 WO0050593 A8 WO 0050593A8
Authority
WO
WIPO (PCT)
Prior art keywords
beta
disease
inner ear
tubulin
meniere
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/004795
Other languages
French (fr)
Other versions
WO2000050593A1 (en
Inventor
Tai June Yoo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Tennessee Research Foundation
Original Assignee
University of Tennessee Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Tennessee Research Foundation filed Critical University of Tennessee Research Foundation
Priority to CA002365101A priority Critical patent/CA2365101A1/en
Priority to AU36057/00A priority patent/AU3605700A/en
Priority to EP00914702A priority patent/EP1157107A1/en
Publication of WO2000050593A1 publication Critical patent/WO2000050593A1/en
Publication of WO2000050593A8 publication Critical patent/WO2000050593A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A Beta-Tubulin antigen present in the membranous structures of the inner ear and an immunoassay method for diagnosing Meniere's disease using the Beta-Tubulin antigen as a target substance for detecting target binding substance in biological fluid from an animal or human having symptoms of a disease of the inner ear.
PCT/US2000/004795 1999-02-25 2000-02-25 Beta-tubulin autoantibody in meniere's disease and other inner ear diseases and a diagnostic method Ceased WO2000050593A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002365101A CA2365101A1 (en) 1999-02-25 2000-02-25 Beta-tubulin autoantibody in meniere's disease and other inner ear diseases and a diagnostic method
AU36057/00A AU3605700A (en) 1999-02-25 2000-02-25 Beta-tubulin autoantibody in meniere's disease and other inner ear diseases and a diagnostic method
EP00914702A EP1157107A1 (en) 1999-02-25 2000-02-25 Beta-tubulin autoantibody in meniere's disease and other inner ear diseases and a diagnostic method using same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12154999P 1999-02-25 1999-02-25
US60/121,549 1999-02-25

Publications (2)

Publication Number Publication Date
WO2000050593A1 WO2000050593A1 (en) 2000-08-31
WO2000050593A8 true WO2000050593A8 (en) 2001-08-02

Family

ID=22397420

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/004795 Ceased WO2000050593A1 (en) 1999-02-25 2000-02-25 Beta-tubulin autoantibody in meniere's disease and other inner ear diseases and a diagnostic method

Country Status (4)

Country Link
EP (1) EP1157107A1 (en)
AU (1) AU3605700A (en)
CA (1) CA2365101A1 (en)
WO (1) WO2000050593A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306615B1 (en) * 1999-08-19 2001-10-23 Tularik Inc. Detection method for monitoring β tubulin isotype specific modification
EP1387888A2 (en) * 2000-12-21 2004-02-11 Incyte Genomics, Inc. Nucleic acid-associated proteins
WO2013130619A1 (en) 2012-02-27 2013-09-06 O-Ray Pharma, Inc. Solid drug implants for intracochlear delivery of therapeutics for the treatment of otic disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993003375A1 (en) * 1991-08-09 1993-02-18 Washington University Autoantibodies and their targets in the diagnosis of peripheral neuropathies
US5885783A (en) * 1997-07-02 1999-03-23 Yoo; Tai-June Autoimmune inner ear disease antigen and diagnostic assay

Also Published As

Publication number Publication date
CA2365101A1 (en) 2000-08-31
EP1157107A1 (en) 2001-11-28
AU3605700A (en) 2000-09-14
WO2000050593A1 (en) 2000-08-31

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