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WO1999063074A3 - Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes - Google Patents

Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes Download PDF

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Publication number
WO1999063074A3
WO1999063074A3 PCT/US1999/012515 US9912515W WO9963074A3 WO 1999063074 A3 WO1999063074 A3 WO 1999063074A3 US 9912515 W US9912515 W US 9912515W WO 9963074 A3 WO9963074 A3 WO 9963074A3
Authority
WO
WIPO (PCT)
Prior art keywords
ligand
altering
nucleic acid
nucleotide composition
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/012515
Other languages
English (en)
Other versions
WO1999063074A2 (fr
Inventor
Michael J Lane
Albert S Benight
Brian D Faldasz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Molecular Diagnostics Inc
Original Assignee
TM Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TM Technologies Inc filed Critical TM Technologies Inc
Publication of WO1999063074A2 publication Critical patent/WO1999063074A2/fr
Publication of WO1999063074A3 publication Critical patent/WO1999063074A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne une méthode permettant d'améliorer le niveau d'expression relatif d'un eukaryote, d'un prokaryiote, d'un virus ou de tout autre gène d'intérêt dans des lignées cellulaires eukaryiotes ou prokaryiotes, ainsi que des procédés et produits connexes.
PCT/US1999/012515 1998-06-04 1999-06-04 Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes Ceased WO1999063074A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8794598P 1998-06-04 1998-06-04
US60/087,945 1998-06-04
US32324499A 1999-06-03 1999-06-03
US09/323,244 1999-06-03

Publications (2)

Publication Number Publication Date
WO1999063074A2 WO1999063074A2 (fr) 1999-12-09
WO1999063074A3 true WO1999063074A3 (fr) 2000-04-06

Family

ID=26777546

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/012515 Ceased WO1999063074A2 (fr) 1998-06-04 1999-06-04 Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes

Country Status (1)

Country Link
WO (1) WO1999063074A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109750039B (zh) * 2019-01-21 2022-09-20 北京大学 一种植物碰触响应启动子及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000665A1 (fr) * 1993-06-17 1995-01-05 The Research Foundation Of State University Of New York Thermodynamique, conception et utilisation de sequences d'acides nucleiques
WO1998037242A1 (fr) * 1997-02-24 1998-08-27 Tm Technologies, Inc. Procede de selection d'oligonucleotides antisens
WO1999032664A1 (fr) * 1997-12-23 1999-07-01 Tm Technologies, Inc. Procede de selection de sequences adjacentes porteuses d'affinites de liaison relatives a un site de liaison aux ligands
WO1999042621A2 (fr) * 1998-02-21 1999-08-26 Tm Technologies, Inc. Proprietes thermodynamiques d'acides nucleiques

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000665A1 (fr) * 1993-06-17 1995-01-05 The Research Foundation Of State University Of New York Thermodynamique, conception et utilisation de sequences d'acides nucleiques
WO1998037242A1 (fr) * 1997-02-24 1998-08-27 Tm Technologies, Inc. Procede de selection d'oligonucleotides antisens
WO1999032664A1 (fr) * 1997-12-23 1999-07-01 Tm Technologies, Inc. Procede de selection de sequences adjacentes porteuses d'affinites de liaison relatives a un site de liaison aux ligands
WO1999042621A2 (fr) * 1998-02-21 1999-08-26 Tm Technologies, Inc. Proprietes thermodynamiques d'acides nucleiques

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Non-contacted sequences flanking a ligand binding site can modulate the affinity of ligand binding: implications of such modulation in single strand to duplex reaction design", BIOPHYSICAL JOURNAL, VOL. 74,NO.2,PART 2, 22 - 26 FEBRUARY 1998, PAGE A5, XP002116814 *

Also Published As

Publication number Publication date
WO1999063074A2 (fr) 1999-12-09

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