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WO1999060371A3 - Method and apparatus for detecting hazardous agents - Google Patents

Method and apparatus for detecting hazardous agents Download PDF

Info

Publication number
WO1999060371A3
WO1999060371A3 PCT/US1999/010770 US9910770W WO9960371A3 WO 1999060371 A3 WO1999060371 A3 WO 1999060371A3 US 9910770 W US9910770 W US 9910770W WO 9960371 A3 WO9960371 A3 WO 9960371A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
chemical
sampler
natural
hazardous agents
Prior art date
Application number
PCT/US1999/010770
Other languages
French (fr)
Other versions
WO1999060371A2 (en
Inventor
Thomas Okarma
Joseph Gold
James Murai
Original Assignee
Geron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geron Corp filed Critical Geron Corp
Priority to AU41885/99A priority Critical patent/AU4188599A/en
Publication of WO1999060371A2 publication Critical patent/WO1999060371A2/en
Publication of WO1999060371A3 publication Critical patent/WO1999060371A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A method and apparatus for determining the presence of a toxic agent, such as a toxic chemical, bacterium, or virus is described. In one embodiment, the apparatus includes a sampler that comprises means for extracting a sample from the environment of the apparatus, such as the ambient atmosphere, water, or soil. Optionally, the sampler can include additional pre-processing means to isolate particular elements of the sample or put the sample in better condition for assay. The apparatus and method can be used to detect a variety of chemical and biological toxins, both natural and non-natural, including chemical and biological toxins of unknown composition and origin.
PCT/US1999/010770 1998-05-15 1999-05-14 Method and apparatus for detecting hazardous agents WO1999060371A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU41885/99A AU4188599A (en) 1998-05-15 1999-05-14 Method and apparatus for detecting hazardous agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8569898P 1998-05-15 1998-05-15
US60/085,698 1998-05-15

Publications (2)

Publication Number Publication Date
WO1999060371A2 WO1999060371A2 (en) 1999-11-25
WO1999060371A3 true WO1999060371A3 (en) 2000-02-10

Family

ID=22193369

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/010770 WO1999060371A2 (en) 1998-05-15 1999-05-14 Method and apparatus for detecting hazardous agents

Country Status (2)

Country Link
AU (1) AU4188599A (en)
WO (1) WO1999060371A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1244215B (en) 1996-11-20 2010-11-03 荷兰克鲁塞尔公司 Improved adenovirus vector production and purification methods
US6447995B1 (en) 2000-10-04 2002-09-10 Genvec, Inc. Utilizing intrinsic fluorescence to detect adenovirus
EP1271145A1 (en) * 2001-06-25 2003-01-02 Cardion AG Methods and cell populations for identifying and validating genomic targets, and for drug screening
WO2003076892A2 (en) * 2001-08-06 2003-09-18 Vanderbilt University Device and methods for measuring the response of at least one cell to a medium

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5661035A (en) * 1995-06-07 1997-08-26 The Regents Of The University Of California Voltage sensing by fluorescence resonance energy transfer
US5660986A (en) * 1987-06-05 1997-08-26 Us Health Immortalized human cell lines containing exogenous cytochrome P450 genes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660986A (en) * 1987-06-05 1997-08-26 Us Health Immortalized human cell lines containing exogenous cytochrome P450 genes
US5661035A (en) * 1995-06-07 1997-08-26 The Regents Of The University Of California Voltage sensing by fluorescence resonance energy transfer

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CELLULAR BIOLOGY AND TOXICOLOGY, vol. 13, no. 6, October 1997 (1997-10-01), pages 435 - 444 *
DATABASE MEDLINE ON DIALOG, CAMILLERI ET AL: "Validity of a Model of cultured Myocardial Cells for Assessment of Cardioplegia" *
HARLE-BACHOR ET AL: "Telomerase Activity in the Regenerative Basal Layer of the Epidermis in Human Skin and in Immortal and Carcinoma-Derived Skin Keratinocytes", PROC. NATL. ACAD. SCI. USA,, vol. 93, June 1996 (1996-06-01), pages 6476 - 6481, XP002923264 *
SEHLMEYER ET AL: "Primordial Germ Cell-derived Embryonic Germ Cells of the Mouse-In Vitro Model for Cytotoxicity Studies with Chemical Mutagens", TOXICOLOGY IN VITRO., vol. 10, 1996, pages 755 - 763, XP002923261 *
STEGMANN ET AL: "Membrane Fusion Activity of Influenza Virus. Effects of Gangliosides and Negatively Charged Phospholipids in Target Liposomes", BIOCHEMISTRY, vol. 28, 1989, pages 1698 - 1704, XP002923263 *
WOBUS ET AL: "In Vitro Cellular Models for Cardiac Development and Pharmacotoxicology", TOXICOLOGY IN VITRO., vol. 9, no. 4, pages 477 - 488, XP002923262 *

Also Published As

Publication number Publication date
WO1999060371A2 (en) 1999-11-25
AU4188599A (en) 1999-12-06

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