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WO1999049922A1 - Inhalateur unidirectionnel pour l'inhalation de substances actives volatiles - Google Patents

Inhalateur unidirectionnel pour l'inhalation de substances actives volatiles Download PDF

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Publication number
WO1999049922A1
WO1999049922A1 PCT/EP1999/002195 EP9902195W WO9949922A1 WO 1999049922 A1 WO1999049922 A1 WO 1999049922A1 EP 9902195 W EP9902195 W EP 9902195W WO 9949922 A1 WO9949922 A1 WO 9949922A1
Authority
WO
WIPO (PCT)
Prior art keywords
sleeve
carrier material
inhaler according
disposable inhaler
nose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1999/002195
Other languages
German (de)
English (en)
Inventor
Georg Mates
Albrecht HÄGE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO1999049922A1 publication Critical patent/WO1999049922A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose

Definitions

  • the invention relates to a disposable inhaler for inhaling volatile active substances through the nose, with at least one tubular sleeve which has a first and a second end, the sleeve for inhalation being insertable into the nose with its first end.
  • the invention further relates to a paper or tissue-like carrier material for forming such a tubular disposable inhaler.
  • the inhaler according to DE 88 00 218 Ul is used for inhaling volatile substances, in particular for the care of the mouth and throat. It consists of a tubular sleeve, namely a cigarette tube, one end of which is closed with a cigarette filter and the other end with a plug made of cellulose or cotton wool.
  • a tubular sleeve namely a cigarette tube, one end of which is closed with a cigarette filter and the other end with a plug made of cellulose or cotton wool.
  • these fillers which contain volatile, inhalable substances, preferably essential oils.
  • this inhaler is "smoked" like a cigarette, but without being lit, i.e. the patient pulls on one of the two stoppers, preferably on the cigarette filter, and thus draws in an air stream which volatilizes or entrains the volatile substances contained in the packing. In this way, the vapors of the volatile substances get into the mouth or throat.
  • the inhaler described in DE 88 01 258 Ul is used to inhale refreshing agents. It also includes a tubular sleeve, but which is made of synthetic resin. A mouthpiece with a suction channel located therein is detachably attached to one end of the sleeve. The other end of the sleeve is provided on the end face with an end wall which has a ventilation opening in the center. The diameter of the ventilation opening is small compared to the diameter of the sleeve.
  • the sleeve itself is filled with synthetic resin fibers impregnated with an aqueous solution of peppermint or a similar refreshing fragrance.
  • this known inhaler includes a cap which, when not in use, is placed over the mouthpiece like a cap of a fountain pen, and a stopper which can be inserted into the ventilation opening at the second end of the sleeve for the same reason.
  • this known inhaler resembles a fountain pen in appearance.
  • This inhaler known from DE 88 01 258 Ul also has the disadvantages already mentioned. Although it has a ventilation opening in the end wall at the second end, it also lacks a continuous, free suction channel, since in this case too the sleeve is completely filled with synthetic resin fibers. In spite of the ventilation opening, a comparatively strong and deep inhalation is therefore also required here to inhale the active substances contained in the inhaler.
  • this inhaler has a comparatively large weight, so that for this reason it is also suitable for permanent inhalation through the nose, as is the subject of the present application is not suitable.
  • the object of the present invention is therefore to create a disposable inhaler of the type mentioned at the outset which is light, has a simple structure and is suitable for inhaling active substances through the nose.
  • the sleeve consists of a thin, paper or fabric-like carrier material which is provided with the active substance at least in some areas.
  • This measure has the advantage that it is now possible to dispense with the use of fillers or fibers for taking up the active ingredient. This also eliminates the need to design the sleeve as a container for receiving fillers or fibers. As a result, end walls or plugs are no longer required.
  • the weight of the inhaler is considerably reduced due to the reduction in the number of individual components. This is in With regard to the use for inhalation through the nose advantageous, so that the inhaler can be used in the sitting or standing position without having to be held by hand and yet not slipping off the nose.
  • the disposable inhaler according to the invention thus offers the advantages of lower air resistance, lower weight and simplified manufacture. This makes it suitable as a disposable inhaler for inhaling active ingredients through the nose.
  • the sleeve has a free suction channel, the clear diameter of which corresponds approximately to the diameter of the sleeve.
  • the active ingredient is applied to the carrier material in an ointment preparation.
  • the inhaler according to the invention can thereby also be used for inhaling active substance preparations which are already commercially available and are available in ointment preparation.
  • the carrier material is impregnated or impregnated with a solution containing the active ingredient.
  • this offers the great advantage that the sleeve is very easy to manufacture, since it can be provided with the active ingredient to be inhaled before it is rolled up.
  • this measure offers the essential advantage that the inhaler according to the invention can also be sold in the form of leaves which have not yet been rolled up but are already provided with the active ingredient to be inhaled. A user can then roll up the flat, sheet-like carrier material even immediately before inhalation in such a way that the diameter of the sleeve is matched to the size of its nostrils.
  • the inhaler according to the invention can also be packed in large quantities in a space-saving manner.
  • the disposable inhaler according to the invention is rolled from a flat, sheet-like carrier material, but is already sold in rolled form as a sleeve. This measure ensures that the sleeve does not unroll before it is used. Of course, this measure can also be done in Connection with the sleeves to be rolled by the user.
  • the carrier material of the sleeve consists of an air-permeable material.
  • This measure has the particular advantage that the air resistance of the sleeve is reduced again, since air is also sucked in through the side walls of the sleeve.
  • Another important advantage is that the dilution of the active ingredient to be inhaled by this air sucked in from the side is even greater, and an active ingredient to be inhaled can thus be applied at the end of the sleeve in a higher and thus a larger active ingredient depot concentration without the Users run the risk of being injured, especially at the beginning of the application, by an excessively high concentration of active substance.
  • the inhaler comprises two of the sleeves mentioned, which are held together by a holding clip.
  • the measure has a particularly advantageous effect if the two sleeves are held in an anatomically adapted shape by the clip.
  • the invention also relates to a paper or tissue-like flat carrier material for forming a tubular disposable inhaler according to the invention described above.
  • the inhaler according to the invention can also be sold in sheet form, so that the sleeve required for inhalation is only rolled up by the user immediately before inhalation.
  • the corresponding paper or tissue-like carrier material is a roll-up sheet with an edge length of a few centimeters, preferably up to about 10 cm, and this sheet is provided with the active ingredient to be inhaled at least in some areas.
  • the sheet-like carrier material can be welded into a film which is torn open, the sheet is removed and rolled into a tube.
  • the inhaler can be given as an insert in magazines or advertising brochures, or laid out and offered for sale in pharmacies or drug stores and displays.
  • This measure has the advantage that the corresponding sheet is particularly easy to manufacture and rolling up the sheet along the edge provided with the active ingredient leads to a sleeve which, according to the advantageous embodiment already mentioned, only in the area of the second end distant from the nostril with the active ingredient to be inhaled.
  • a disposable inhaler according to the present invention in its various configurations is excellently suitable for nasal cold inhalation of active ingredients, for example for the inhalation of essential oils.
  • Cold inhalation means that the active ingredients for inhalation do not first have to be evaporated by heating, but can already be inhaled together with the breathing air at normal room temperature.
  • Such nasal inhalation with suitable active ingredients improves nasal breathing, facilitates gas exchange during breathing and finally stimulates the blood flow to the nasal mucosa.
  • the active substance applied to the carrier material of the sleeve reaches the nose with the inhaled air and, moreover, also in the upper airways with the pharynx, paranasal sinuses and even the bronchi.
  • Active ingredient is enriched and which flows through the mucous membrane areas of the nose. Depending on the active ingredient selected, an anti-inflammatory or decongestant effect can be achieved.
  • the cold inhalation possible with the inhaler according to the invention is significantly more gentle on the mucous membrane and skin.
  • the inhaler according to the invention can also be used for oral inhalation.
  • FIG. 1 is a schematic representation of a disposable inhaler according to the invention consisting of two sleeves which are inserted into the nostrils of a nose,
  • Fig. 4 shows a sleeve for use as a disposable inhaler, which is secured with a fixation against unrolling and
  • Fig. 5 shows a sleeve for use as a disposable inhaler, which is fixed against unrolling.
  • a disposable inhaler according to the invention is designated in its entirety with the reference number 10.
  • the disposable inhaler 10 comprises two sleeves 12, 14, each having a first end 16 and a second end 18.
  • Each of the two sleeves 12, 14 surrounds a suction channel 20.
  • the two ends 16, 18 of the sleeves 12, 14 are each open and form a first opening 22 at the first end 16 and a second opening 24 at the second end 18.
  • the diameter 26 of the suction channel 20 corresponds to the clear diameter 28 of the sleeve 12, 14.
  • each sleeve 12, 14 is inserted into a nostril 30 of a nose 32.
  • the sleeves 12, 14 are provided with an active ingredient 34 to be inhaled.
  • a holding clip 36 holds the two sleeves 12, 14 together in an anatomically advantageous manner.
  • the carrier material of the sleeves 12, 14 here consists of an air-permeable material, namely cellulose.
  • air 40 can also enter the sleeves 12, 14 laterally.
  • the air 40 mixes in the suction channel 20 of the sleeves 12, 14 with the air 38 sucked in through the opening 24, which pulls the active substance 34 with it. This mixing reduces the concentration of the active substance 34 to such an extent that irritation or corrosion of the nasal mucous membranes of the nose 32 is avoided.
  • the first ends 16 of the sleeves 12, 14 are shaped in a manner which is not visible here, in a manner appropriate for the nose. This can be, for example, a taper adapted to the shape of the nasal cavities.
  • the ends 16 of the sleeves 12, 14 can be provided from a thicker layer of the carrier material or, for example, also with an additional, additional material layer 15
  • the sheet 42 shows a flat, sheet-like carrier material for forming a tubular disposable inhaler 10.
  • the sheet 42 is provided with the active ingredient 34 to be inhaled along an edge 44. This can be done, for example, by applying the active ingredient 34 in an ointment preparation or by impregnating or impregnating the sheet 42 with a solution containing the active ingredient 34.
  • the sheet 42 is approximately rectangular.
  • the sheet 42 is sealed in an airtight packaging, for example in a film, which has been removed beforehand.
  • the sheet 42 Transversely to the edge 44, the sheet 42 has a fixing tab 46 provided with a pressure-sensitive adhesive, by means of which the sheet 42 can be secured against unrolling after being rolled up.
  • FIG. 3 shows how the sheet 42 can be rolled up in the direction of the arrows 48 to form a sleeve 12, 14.
  • Fig. 4 shows a resulting sleeve 12, which is secured by means of the fixing tab 46 against unrolling.
  • this can be an adhesive surface to be activated by moisture, as is known, for example, from cigarette paper for rolling cigarettes yourself. Because of the fixing tab 46, the sleeve remains in the rolled-up state and forms the diameter 26 that is then fixed 16
  • Suction channel 20 As a result, it can be adapted to the respective size of the nostril 30, that is to say whether, for example, a child or an adult is using the inhaler.
  • the layers of the sheet 42 which are wound one above the other and which are visible at the opening 22 are shown for clarity at a greater distance from one another than this actually results when a sheet 42 is wound up.
  • the diameter of the suction channel 20 formed within the sleeve 12 will approximately correspond to the diameter 28 of the sleeve 12. If the inhaler is offered as a separate sleeve 12, this is also provided by the manufacturer with a protective cover which is removed before use.
  • Fig. 5 shows a sleeve 12 which is rolled from a sheet 42 without a fixing tab 46. Due to the lack of fixation, the sheet 42 will attempt to unroll in the direction of the arrows 50, 52. As already mentioned above, the force effect on which this process is based can be used to hold the sleeve 12 in place when it is inserted into the nostril 30.
  • a disposable inhaler according to this invention can of course also be made from a sleeve alone 12 exist. This can, for example, be rolled out of a sheet 42 in accordance with FIG. 4 or FIG. 5.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

Inhalateur unidirectionnel (10) pour l'inhalation, par voies nasales (32),de substances actives volatiles, comprenant au moins un manchon tubulaire (12, 14) présentant une première (16) et une deuxième (18) extrémités, le manchon (12, 14) pouvant être inséré dans le nez (32), par sa première extrémité, en vue de l'inhalation, caractérisé en ce que le manchon (12, 14) est constitué par un matériau support mince, en papier ou du genre tissu garni, au moins par zones, de la substance active.
PCT/EP1999/002195 1998-03-31 1999-03-30 Inhalateur unidirectionnel pour l'inhalation de substances actives volatiles Ceased WO1999049922A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998114324 DE19814324C1 (de) 1998-03-31 1998-03-31 Einweginhalator zum Inhalieren von flüchtigen Wirkstoffen
DE19814324.9 1998-03-31

Publications (1)

Publication Number Publication Date
WO1999049922A1 true WO1999049922A1 (fr) 1999-10-07

Family

ID=7863063

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/002195 Ceased WO1999049922A1 (fr) 1998-03-31 1999-03-30 Inhalateur unidirectionnel pour l'inhalation de substances actives volatiles

Country Status (2)

Country Link
DE (1) DE19814324C1 (fr)
WO (1) WO1999049922A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002078774A1 (fr) * 2001-03-28 2002-10-10 Direct-Haler A/S Systeme permettant de s'assurer de la distribution de medicaments
DE202008013614U1 (de) 2008-10-14 2009-02-12 Wesner, Ewald, Dipl.-Ing. Duftstoffspeicher- und Leitungssystem

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007010246A1 (de) * 2007-03-02 2008-09-04 Bernhard Mailinger Vorrichtung zur oralen Inhalation
DE202011102694U1 (de) * 2011-06-29 2011-12-19 Zisser Gmbh Inhalationsgerät für Heimanwender

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB371802A (en) * 1930-04-11 1932-04-28 Nasalets Inc Nasal pellets
FR1254549A (fr) * 1960-01-14 1961-02-24 Dispositif servant à la désinfection et au traitement des voies respiratoires
DE8800218U1 (de) 1988-01-11 1988-02-25 Burger Söhne AG Burg, Burg Inhalator
DE8801258U1 (de) 1988-01-05 1988-03-31 Aruman Co., Ltd., Tokio/Tokyo Einweginhalationsgerät für Erfrischungsmittel
FR2649894A1 (fr) * 1989-07-19 1991-01-25 Fact Anal Scp Inhalateur individuel de poche
WO1996022802A1 (fr) * 1995-01-23 1996-08-01 Direct-Haler A/S Inhalateur
FR2731911A1 (fr) * 1995-03-20 1996-09-27 Paul Seyvos Dispositif qui permet d'inhaler, par la bouche, l' odeur de produits contenus dans un reservoir a des fins therapeutiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4221217A (en) * 1978-05-01 1980-09-09 Amezcua Saul O Nasal device
US4401117A (en) * 1981-02-23 1983-08-30 Hyman Gershuny Therapeutic appliance
DE4038546A1 (de) * 1989-12-11 1991-06-13 Dirk Dr Grundmann Inhaliergeraet

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB371802A (en) * 1930-04-11 1932-04-28 Nasalets Inc Nasal pellets
FR1254549A (fr) * 1960-01-14 1961-02-24 Dispositif servant à la désinfection et au traitement des voies respiratoires
DE8801258U1 (de) 1988-01-05 1988-03-31 Aruman Co., Ltd., Tokio/Tokyo Einweginhalationsgerät für Erfrischungsmittel
DE8800218U1 (de) 1988-01-11 1988-02-25 Burger Söhne AG Burg, Burg Inhalator
FR2649894A1 (fr) * 1989-07-19 1991-01-25 Fact Anal Scp Inhalateur individuel de poche
WO1996022802A1 (fr) * 1995-01-23 1996-08-01 Direct-Haler A/S Inhalateur
FR2731911A1 (fr) * 1995-03-20 1996-09-27 Paul Seyvos Dispositif qui permet d'inhaler, par la bouche, l' odeur de produits contenus dans un reservoir a des fins therapeutiques

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002078774A1 (fr) * 2001-03-28 2002-10-10 Direct-Haler A/S Systeme permettant de s'assurer de la distribution de medicaments
DE202008013614U1 (de) 2008-10-14 2009-02-12 Wesner, Ewald, Dipl.-Ing. Duftstoffspeicher- und Leitungssystem

Also Published As

Publication number Publication date
DE19814324C1 (de) 2000-01-20

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