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WO1999049024A8 - Methods and compositions for production of multimeric proteins in transgenic plants - Google Patents

Methods and compositions for production of multimeric proteins in transgenic plants

Info

Publication number
WO1999049024A8
WO1999049024A8 PCT/US1999/006506 US9906506W WO9949024A8 WO 1999049024 A8 WO1999049024 A8 WO 1999049024A8 US 9906506 W US9906506 W US 9906506W WO 9949024 A8 WO9949024 A8 WO 9949024A8
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
production
methods
transgenic plants
plant cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/006506
Other languages
French (fr)
Other versions
WO1999049024A2 (en
WO1999049024A3 (en
WO1999049024A9 (en
Inventor
Keith L Wycoff
Sudhir K Jaiswal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Planet Biotechnology Inc
Original Assignee
Planet Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Planet Biotechnology Inc filed Critical Planet Biotechnology Inc
Priority to AU31152/99A priority Critical patent/AU3115299A/en
Publication of WO1999049024A2 publication Critical patent/WO1999049024A2/en
Publication of WO1999049024A3 publication Critical patent/WO1999049024A3/en
Publication of WO1999049024A8 publication Critical patent/WO1999049024A8/en
Publication of WO1999049024A9 publication Critical patent/WO1999049024A9/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

This invention is related to the field of methods and compositions for production of multimeric proteins in transgenic plants. The invention provides a method for producing a heterologous multimeric protein in a transgenic plant cell by transforming a plant cell with a plurality of naked plasmids. Each plasmid encodes less than all of the polypeptide components of the multimeric protein, and the plurality of transformed plasmids encodes all of the polypeptide components of the multimeric protein. The invention also provides a transgenic plant or plant cell expressing a multimeric protein that is heterologous to the plant cell.
PCT/US1999/006506 1998-03-25 1999-03-24 Methods and compositions for production of multimeric proteins in transgenic plants Ceased WO1999049024A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU31152/99A AU3115299A (en) 1998-03-25 1999-03-24 Methods and compositions for production of multimeric proteins in transgenic plants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7924998P 1998-03-25 1998-03-25
US60/079,249 1998-03-25

Publications (4)

Publication Number Publication Date
WO1999049024A2 WO1999049024A2 (en) 1999-09-30
WO1999049024A3 WO1999049024A3 (en) 1999-11-25
WO1999049024A8 true WO1999049024A8 (en) 2000-03-02
WO1999049024A9 WO1999049024A9 (en) 2000-04-27

Family

ID=22149351

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/006506 Ceased WO1999049024A2 (en) 1998-03-25 1999-03-24 Methods and compositions for production of multimeric proteins in transgenic plants

Country Status (2)

Country Link
AU (1) AU3115299A (en)
WO (1) WO1999049024A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020168367A1 (en) * 2000-04-28 2002-11-14 Planet Biotechnology Incorporated Novel immunoadhesins for treating and preventing viral and bacterial diseases
CN101643512A (en) 2000-04-28 2010-02-10 行星生物技术有限公司 Novel immunoadhesin for the prevention of rhinovirus infection
EP2573177B1 (en) 2007-11-12 2022-12-28 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes
WO2013087911A1 (en) 2011-12-16 2013-06-20 Synthon Biopharmaceuticals B.V. Compounds and methods for treating inflammatory diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5959177A (en) * 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
JPH11504901A (en) * 1994-12-30 1999-05-11 プラネット・バイオテクノロジー・インコーポレイテッド Method for producing immunoglobulins containing defense proteins in plants and their use
WO1999007210A1 (en) * 1997-08-12 1999-02-18 North Carolina State University Genetically engineered duckweed

Also Published As

Publication number Publication date
WO1999049024A2 (en) 1999-09-30
WO1999049024A3 (en) 1999-11-25
WO1999049024A9 (en) 2000-04-27
AU3115299A (en) 1999-10-18

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