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WO1998029110A3 - Preparation et methode de traitement de neoplasmes par inhalation - Google Patents

Preparation et methode de traitement de neoplasmes par inhalation Download PDF

Info

Publication number
WO1998029110A3
WO1998029110A3 PCT/US1997/024289 US9724289W WO9829110A3 WO 1998029110 A3 WO1998029110 A3 WO 1998029110A3 US 9724289 W US9724289 W US 9724289W WO 9829110 A3 WO9829110 A3 WO 9829110A3
Authority
WO
WIPO (PCT)
Prior art keywords
inhalation
formulation
treating neoplasms
composition
neoplasms
Prior art date
Application number
PCT/US1997/024289
Other languages
English (en)
Other versions
WO1998029110A2 (fr
Inventor
Michael E Placke
Anthony R Imondi
Michael J Brooker
John E Frye
Praful K Shah
Douglas R Flanagan Jr
Maureen D Donovan
Original Assignee
Battelle Memorial Institute
Michael E Placke
Anthony R Imondi
Michael J Brooker
John E Frye
Praful K Shah
Douglas R Flanagan Jr
Maureen D Donovan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute, Michael E Placke, Anthony R Imondi, Michael J Brooker, John E Frye, Praful K Shah, Douglas R Flanagan Jr, Maureen D Donovan filed Critical Battelle Memorial Institute
Priority to EP97955033A priority Critical patent/EP0954283B1/fr
Priority to JP53035898A priority patent/JP2001513078A/ja
Priority to AU70975/98A priority patent/AU741439B2/en
Priority to CA002275889A priority patent/CA2275889C/fr
Priority to NZ336381A priority patent/NZ336381A/xx
Priority to BR9713661-1A priority patent/BR9713661A/pt
Priority to DE69737510T priority patent/DE69737510T2/de
Publication of WO1998029110A2 publication Critical patent/WO1998029110A2/fr
Publication of WO1998029110A3 publication Critical patent/WO1998029110A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne une préparation, une méthode et un appareil de traitement de néoplasmes tels que le cancer par absorption, par l'administration par inhalation, d'une quantité efficace du point de vue pharmaceutique d'une composition très toxique, la composition se constituant d'un médicament antinéoplasique non encapsulé.
PCT/US1997/024289 1996-12-30 1997-12-30 Preparation et methode de traitement de neoplasmes par inhalation WO1998029110A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP97955033A EP0954283B1 (fr) 1996-12-30 1997-12-30 Utilisation d'un agent anti-cancereux non encapsule pour la preparation d'une composition pour le traitement de neoplasmes par inhalation
JP53035898A JP2001513078A (ja) 1996-12-30 1997-12-30 吸入により新生物を治療する製剤とその方法
AU70975/98A AU741439B2 (en) 1996-12-30 1997-12-30 Formulation and method for treating neoplasms by inhalation
CA002275889A CA2275889C (fr) 1996-12-30 1997-12-30 Preparation et methode de traitement de neoplasmes par inhalation
NZ336381A NZ336381A (en) 1996-12-30 1997-12-30 Formulation and method for treating neoplasms by inhalation
BR9713661-1A BR9713661A (pt) 1996-12-30 1997-12-30 Formulação e método para o tratamento de neoplasmas por inalação
DE69737510T DE69737510T2 (de) 1996-12-30 1997-12-30 Verwendung eines unverkapselten Antikrebs-Arzneimittels zur Herstellung einer Zubereitung zur Behandlung von Neoplasmen durch Inhalation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3378996P 1996-12-30 1996-12-30
US60/033,789 1996-12-30

Publications (2)

Publication Number Publication Date
WO1998029110A2 WO1998029110A2 (fr) 1998-07-09
WO1998029110A3 true WO1998029110A3 (fr) 1999-04-15

Family

ID=21872447

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/024289 WO1998029110A2 (fr) 1996-12-30 1997-12-30 Preparation et methode de traitement de neoplasmes par inhalation

Country Status (12)

Country Link
US (5) US6471943B1 (fr)
EP (1) EP0954283B1 (fr)
JP (1) JP2001513078A (fr)
CN (1) CN1245423A (fr)
AT (1) ATE357214T1 (fr)
AU (1) AU741439B2 (fr)
BR (1) BR9713661A (fr)
CA (2) CA2628857C (fr)
DE (1) DE69737510T2 (fr)
ES (1) ES2285743T3 (fr)
NZ (1) NZ336381A (fr)
WO (1) WO1998029110A2 (fr)

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US7537009B2 (en) 2001-06-05 2009-05-26 Alexza Pharmaceuticals, Inc. Method of forming an aerosol for inhalation delivery
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
US7581540B2 (en) 2004-08-12 2009-09-01 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US8991387B2 (en) 2003-05-21 2015-03-31 Alexza Pharmaceuticals, Inc. Self-contained heating unit and drug-supply unit employing same
US9211382B2 (en) 2001-05-24 2015-12-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits

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US6471943B1 (en) 2002-10-29
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US20010036444A1 (en) 2001-11-01
ATE357214T1 (de) 2007-04-15
EP0954283A2 (fr) 1999-11-10
ES2285743T3 (es) 2007-11-16
US20020155066A1 (en) 2002-10-24
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US6348209B2 (en) 2002-02-19
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CA2275889A1 (fr) 1998-07-09
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US20010038827A1 (en) 2001-11-08
DE69737510T2 (de) 2007-12-06
AU7097598A (en) 1998-07-31
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US6419900B2 (en) 2002-07-16
AU741439B2 (en) 2001-11-29
US20010038826A1 (en) 2001-11-08
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EP0954283B1 (fr) 2007-03-21
US6419901B2 (en) 2002-07-16

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