WO1998016873A1 - Procede de preparation de dispersions a base de composants chromogenes - Google Patents
Procede de preparation de dispersions a base de composants chromogenes Download PDFInfo
- Publication number
- WO1998016873A1 WO1998016873A1 PCT/RU1996/000298 RU9600298W WO9816873A1 WO 1998016873 A1 WO1998016873 A1 WO 1998016873A1 RU 9600298 W RU9600298 W RU 9600298W WO 9816873 A1 WO9816873 A1 WO 9816873A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dispersion
- chτο
- κοmποnenτy
- sποsοb
- mixture
- Prior art date
Links
- 239000006185 dispersion Substances 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title claims abstract description 24
- 239000000203 mixture Substances 0.000 claims abstract description 25
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims abstract description 12
- 125000004122 cyclic group Chemical group 0.000 claims abstract description 4
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims abstract description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 3
- 239000000446 fuel Substances 0.000 claims description 4
- 239000000443 aerosol Substances 0.000 claims description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 abstract description 7
- 239000000243 solution Substances 0.000 abstract description 7
- 230000015271 coagulation Effects 0.000 abstract description 3
- 238000005345 coagulation Methods 0.000 abstract description 3
- 239000002904 solvent Substances 0.000 abstract description 3
- 239000007864 aqueous solution Substances 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract 2
- 238000009835 boiling Methods 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003377 silicon compounds Chemical class 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 125000000725 trifluoropropyl group Chemical group [H]C([H])(*)C([H])([H])C(F)(F)F 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000004606 Fillers/Extenders Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 1
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical class OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000012993 chemical processing Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- VVSMKOFFCAJOSC-UHFFFAOYSA-L disodium;dodecylbenzene;sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1 VVSMKOFFCAJOSC-UHFFFAOYSA-L 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- CXPOFJRHCFPDRI-UHFFFAOYSA-N dodecylbenzene;sulfuric acid Chemical compound OS(O)(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1 CXPOFJRHCFPDRI-UHFFFAOYSA-N 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000001132 ultrasonic dispersion Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03C—PHOTOSENSITIVE MATERIALS FOR PHOTOGRAPHIC PURPOSES; PHOTOGRAPHIC PROCESSES, e.g. CINE, X-RAY, COLOUR, STEREO-PHOTOGRAPHIC PROCESSES; AUXILIARY PROCESSES IN PHOTOGRAPHY
- G03C7/00—Multicolour photographic processes or agents therefor; Regeneration of such processing agents; Photosensitive materials for multicolour processes
- G03C7/30—Colour processes using colour-coupling substances; Materials therefor; Preparing or processing such materials
- G03C7/388—Processes for the incorporation in the emulsion of substances liberating photographically active agents or colour-coupling substances; Solvents therefor
Definitions
- the invention is used for the production of dispersions of color components and may be used in the treatment of cerebrovascular accidents.
- the closest analogue is the method of manufacturing dispersions of color components described in the patent of the Russian Federation
- the dispersion with the maximum content of components is not more than 8.8 mass%.
- the technical task of the present invention is to increase the coagulative stability of dispersion when stored with a simultaneous increase in the rate of discrimination.
- ⁇ 2 , ⁇ 3 have the above meanings.
- Primary urban compound of formula I or a mixture of compounds of formula I are usually introduced in quantities of 0.5 to 10.0% of the mass of the high-quality extender.
- the compounds of formula I or their mixtures are optimally dependent on the use of a high-output solvent or a mixture of the specified process and the specified mixture.
- izg ⁇ vleniya dis ⁇ e ⁇ sy g ⁇ lub ⁇ y tsve ⁇ b ⁇ azuyuschey ⁇ m ⁇ nen ⁇ y s ⁇ edinenie ⁇ muly I ne ⁇ b ⁇ dim ⁇ vzya ⁇ in ⁇ liches ⁇ ve 1 , 0% of the mass of the mixture of high-leveling agents.
- the average particle diameter of the dispersion is 0.14 -0.16 ⁇ m, which lasts for 6 months without any signs of coagulation.
- the use of a mixture of darker organic compounds of the general formula I allows you to regulate the profitability of the property due to changes in the percentage of concentration.
- non-commercial fillers with a specific rate of 100-400 m 2 in the amount of 0.1-5.0 wt.
- the proposed method of generating dispersion can be implemented using, for example, a randomized pulsed device, [1]. However, it is preferable to manage the dispersion process by the influence of ultrasonic vibrations.
- Other devices may, for example, have magnetic or piezoelectric ultrasonic dispersion.
- an ultrasound generator combined with a pulsed device may be used.
- Such devices are in the patent [3].
- the center has, at least, a single access point located in the area of rotation of the unit.
- a popular pulsed device is discharged in an international application [4].
- P ⁇ ed ⁇ ch ⁇ i ⁇ eln ⁇ is ⁇ lz ⁇ vanie us ⁇ ve ⁇ shens ⁇ v ⁇ vann ⁇ g ⁇ ⁇ n ⁇ - ⁇ ulsatsi ⁇ nn ⁇ g ⁇ a ⁇ a ⁇ a in ⁇ m ⁇ and s ⁇ a ⁇ imeyu ⁇ on ⁇ b ⁇ aschenny ⁇ d ⁇ ug ⁇ d ⁇ ugu ⁇ ve ⁇ n ⁇ s ⁇ ya ⁇ ⁇ u ⁇ bulizi ⁇ uyuschie elemen ⁇ y, ⁇ i e ⁇ m on dis ⁇ e ⁇ a between ⁇ u ⁇ bulizi ⁇ uyuschimi elemen ⁇ ami vy ⁇ lneny nasech ⁇ i and / or ⁇ ⁇ 98/16873 ⁇ 96 / 00298
- ⁇ ⁇ aches ⁇ ve gid ⁇ bny ⁇ tsve ⁇ b ⁇ azuyuschi ⁇ ⁇ m ⁇ nen ⁇ is ⁇ lz ⁇ valis, na ⁇ ime ⁇ , g ⁇ lubaya tsve ⁇ b ⁇ azuyuschaya ⁇ m ⁇ nen ⁇ a: ⁇ - (2,4- di ⁇ e ⁇ amil ⁇ en ⁇ si) - ⁇ ilamid -1 - ⁇ si-2,4 - di ⁇ l ⁇ - -3 - me ⁇ ilbenz ⁇ yn ⁇ y ⁇ isl ⁇ y (C-213), ⁇ u ⁇ u ⁇ naya tsve ⁇ b ⁇ azuyuschaya ⁇ m ⁇ nen ⁇ a:
- This example is a method of production [1].
- Non-rust steel equipment for example 1, is loaded with 29.5 liters of water and 0.86 kg of dodecylbenzene sulfate (21, 3% of basic material). The resulting solution mixes for 2 minutes at a temperature of 60-65 ° ⁇ .
- a 4.0-yellow product is available in a mixture of high-performance apertures and auxiliaries.
- the obtained product of a color-forming component is dispersed in a separate unit for the production of de-decylbenzene sulfate for 6 minutes at 70-75 ° ⁇ .
- Table 2 shows the data from the tests of the color photo paper "News” nostic "Slavich", the city of Peslavl-Zalessky, received a warning on 6-56-00-83 Chemical processing of the obtained photo paper was carried out in the minigab of the “ ⁇ ” company ⁇ ⁇ ⁇ ⁇ 4 4 4 4-4. For comparison, the results of sensory tests of the color photo paper of the utility paper, processed in similar conditions, are presented.
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Cette invention concerne un procédé de préparation de dispersions à base de composants chromogènes, lequel procédé peut être utilisé dans le domaine de l'industrie chimique et photographique. Cette invention permet d'accroître la stabilité de coagulation des dispersions lors du stockage de ces dernières, ceci tout en augmentant la concentration du composant dans une dispersion. A cette fin, les composants chromogènes sont dissous dans un solvant organique possédant un point d'ébullition élevé ou dans un mélange de tels solvants. La solution ainsi obtenue est ensuite dispersée dans une solution aqueuse d'une substance tensioactive ionogène. On ajoute en outre, avant ou après la dissolution des composants chromogènes, au moins un composé de silicium organique linéaire ou cyclique correspondant à la formule générale (I). Lorsque n varie de 0 à 300, R1, RI1, R2 et R3 peuvent être identiques ou différents et représentent un radical organique choisi dans le groupe comprenant alkyle inférieur, méthyle, éthyle, phényle, trifluoropropyle. Lorsque n varie de 0 à 1, R¿1? correspond à la formule (a) tandis que R?I¿1 correspond à la formule (b), R2 et R3 étant tels que définis précédemment. Il est en outre préférable d'utiliser un copolymère correspondant à la formule générale (II) où X représente de 5,0 à 7,0 parts en poids et Y représente de 0,2 à 0,7 parts en poids, avec une viscosité spécifique d'une solution à 0,5 % dans de l'acétone allant de 0,1 à 0,5. Le processus de dispersion se fait de préférence à l'aide de vibrations ultrasoniques.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU1996/000298 WO1998016873A1 (fr) | 1996-10-14 | 1996-10-14 | Procede de preparation de dispersions a base de composants chromogenes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU1996/000298 WO1998016873A1 (fr) | 1996-10-14 | 1996-10-14 | Procede de preparation de dispersions a base de composants chromogenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1998016873A1 true WO1998016873A1 (fr) | 1998-04-23 |
Family
ID=20130052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/RU1996/000298 WO1998016873A1 (fr) | 1996-10-14 | 1996-10-14 | Procede de preparation de dispersions a base de composants chromogenes |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO1998016873A1 (fr) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7118915B2 (en) | 2001-09-27 | 2006-10-10 | Pieris Proteolab Ag | Muteins of apolipoprotein D |
| US7252998B2 (en) | 2001-09-27 | 2007-08-07 | Pieris Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| US10400016B2 (en) | 2015-12-10 | 2019-09-03 | Pieris Pharmaceuticals Gmbh | Proteins specific for calcitonin gene-related peptide |
| US10526382B2 (en) | 2015-01-28 | 2020-01-07 | Pieris Pharmaceuticals Gmbh | Human neutrophil gelatinase-associated lipocalin (hNGAL) muteins capable of binding angiopoietin-2 (Ang-2) and methods of use thereof |
| US10526384B2 (en) | 2012-11-19 | 2020-01-07 | Pieris Pharmaceuticals Gmbh | Interleukin-17A-specific and interleukin-23-specific binding polypeptides and uses thereof |
| US10618941B2 (en) | 2009-12-07 | 2020-04-14 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 (Lcn2,hNGAL) with affinity for a given target |
| US10703810B2 (en) | 2015-11-30 | 2020-07-07 | Pieris Australia Pty Ltd. | Fusion polypeptides which bind vascular endothelial growth factor a (VEGF-A) and angiopoietin-2 (Ang-2) |
| US10774119B2 (en) | 2014-05-22 | 2020-09-15 | Pieris Pharmaceuticals Gmbh | Specific-binding polypeptides and uses thereof |
| US10787491B2 (en) | 2015-05-18 | 2020-09-29 | Pieris Pharmaceuticals Gmbh | Nucleic acid molecules encoding muteins of human lipocalin 2 with affinity for glypican-3 (GPC3) |
| US10865250B2 (en) | 2015-05-04 | 2020-12-15 | Pieris Pharmaceuticals Gmbh | Anti-cancer fusion polypeptide |
| US10913778B2 (en) | 2015-05-18 | 2021-02-09 | Pieris Pharmaceuticals Gmbh | Anti-cancer fusion polypeptides, encoding nucleic acids and methods of using polypeptides |
| US10927154B2 (en) | 2014-01-13 | 2021-02-23 | Pieris Pharmaceuticals Gmbh | Multi-specific polypeptide useful for localized tumor immunomodulation |
| US11261221B2 (en) | 2015-05-04 | 2022-03-01 | Pieris Pharmaceuticals Gmbh | Proteins specific for CD137 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD277343A1 (de) * | 1988-11-21 | 1990-03-28 | Wolfen Filmfab Veb | Verfahren zur dispergierung hydrophober komponenten |
| EP0555923A2 (fr) * | 1992-02-10 | 1993-08-18 | Eastman Kodak Company | Dispersions d'additifs photographiques et méthode pour leur préparation |
| RU2050569C1 (ru) * | 1992-05-26 | 1995-12-20 | Федоров Александр Дмитриевич | Способ получения тонких дисперсий гидрофобных цветообразующих компонент и устройство для его осуществления |
| RU2052843C1 (ru) * | 1994-05-20 | 1996-01-20 | Товарищество с ограниченной ответственностью Фирма "Форсат" | Способ подготовки к поливу цветных галогенсеребряных фотографических эмульсий |
| RU2052844C1 (ru) * | 1994-05-20 | 1996-01-20 | Товарищество с ограниченной ответственностью Фирма "Форсат" | Способ изготовления дисперсий цветообразующих компонент |
| SU1409036A1 (ru) * | 1986-07-14 | 1996-02-10 | Казанский Научно-Исследовательский Технологический И Проектный Институт Химико-Фотографической Промышленности | Способ получения тонких дисперсий защищаемых цветных компонент |
-
1996
- 1996-10-14 WO PCT/RU1996/000298 patent/WO1998016873A1/fr active Application Filing
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1409036A1 (ru) * | 1986-07-14 | 1996-02-10 | Казанский Научно-Исследовательский Технологический И Проектный Институт Химико-Фотографической Промышленности | Способ получения тонких дисперсий защищаемых цветных компонент |
| DD277343A1 (de) * | 1988-11-21 | 1990-03-28 | Wolfen Filmfab Veb | Verfahren zur dispergierung hydrophober komponenten |
| EP0555923A2 (fr) * | 1992-02-10 | 1993-08-18 | Eastman Kodak Company | Dispersions d'additifs photographiques et méthode pour leur préparation |
| RU2050569C1 (ru) * | 1992-05-26 | 1995-12-20 | Федоров Александр Дмитриевич | Способ получения тонких дисперсий гидрофобных цветообразующих компонент и устройство для его осуществления |
| RU2052843C1 (ru) * | 1994-05-20 | 1996-01-20 | Товарищество с ограниченной ответственностью Фирма "Форсат" | Способ подготовки к поливу цветных галогенсеребряных фотографических эмульсий |
| RU2052844C1 (ru) * | 1994-05-20 | 1996-01-20 | Товарищество с ограниченной ответственностью Фирма "Форсат" | Способ изготовления дисперсий цветообразующих компонент |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7118915B2 (en) | 2001-09-27 | 2006-10-10 | Pieris Proteolab Ag | Muteins of apolipoprotein D |
| US7252998B2 (en) | 2001-09-27 | 2007-08-07 | Pieris Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| US10618941B2 (en) | 2009-12-07 | 2020-04-14 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 (Lcn2,hNGAL) with affinity for a given target |
| US11827681B2 (en) | 2009-12-07 | 2023-11-28 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 (Lcn2, hNGAL) with affinity for a given target |
| US10526384B2 (en) | 2012-11-19 | 2020-01-07 | Pieris Pharmaceuticals Gmbh | Interleukin-17A-specific and interleukin-23-specific binding polypeptides and uses thereof |
| US10927154B2 (en) | 2014-01-13 | 2021-02-23 | Pieris Pharmaceuticals Gmbh | Multi-specific polypeptide useful for localized tumor immunomodulation |
| US11345728B2 (en) | 2014-05-22 | 2022-05-31 | Pieris Pharmaceuticals Gmbh | Specific-binding polypeptides and uses thereof |
| US10774119B2 (en) | 2014-05-22 | 2020-09-15 | Pieris Pharmaceuticals Gmbh | Specific-binding polypeptides and uses thereof |
| US10526382B2 (en) | 2015-01-28 | 2020-01-07 | Pieris Pharmaceuticals Gmbh | Human neutrophil gelatinase-associated lipocalin (hNGAL) muteins capable of binding angiopoietin-2 (Ang-2) and methods of use thereof |
| US11034738B2 (en) | 2015-01-28 | 2021-06-15 | Pieris Pharmaceuticals Gmbh | Nucleic acid molecules encoding human neutrophil gelatinase-associated lipocalin (hNGAL) which bind angiopoietin-2 (Ang-2) |
| US10865250B2 (en) | 2015-05-04 | 2020-12-15 | Pieris Pharmaceuticals Gmbh | Anti-cancer fusion polypeptide |
| US12195503B2 (en) | 2015-05-04 | 2025-01-14 | Pieris Pharmaceuticals Gmbh | Proteins specific for CD137 |
| US11261221B2 (en) | 2015-05-04 | 2022-03-01 | Pieris Pharmaceuticals Gmbh | Proteins specific for CD137 |
| US10787491B2 (en) | 2015-05-18 | 2020-09-29 | Pieris Pharmaceuticals Gmbh | Nucleic acid molecules encoding muteins of human lipocalin 2 with affinity for glypican-3 (GPC3) |
| US10913778B2 (en) | 2015-05-18 | 2021-02-09 | Pieris Pharmaceuticals Gmbh | Anti-cancer fusion polypeptides, encoding nucleic acids and methods of using polypeptides |
| US10703810B2 (en) | 2015-11-30 | 2020-07-07 | Pieris Australia Pty Ltd. | Fusion polypeptides which bind vascular endothelial growth factor a (VEGF-A) and angiopoietin-2 (Ang-2) |
| US11034737B2 (en) | 2015-12-10 | 2021-06-15 | Pieris Pharmaceuticals Gmbh | Proteins specific for calcitonin gene-related peptide |
| US10400016B2 (en) | 2015-12-10 | 2019-09-03 | Pieris Pharmaceuticals Gmbh | Proteins specific for calcitonin gene-related peptide |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO1998016873A1 (fr) | Procede de preparation de dispersions a base de composants chromogenes | |
| EP0161821B1 (fr) | Compositions explosives à base d'émulsion eau-dans-huile sensibilisées par des bulles de gaz | |
| EP0028884B1 (fr) | Composition de bouillie explosive et procédé pour sa préparation | |
| KR940005681A (ko) | 친수성 중심을 갖는 폴리비닐아민 유도체, 이의 제조방법 및 약제, 활성 화합물 담체 및 식품 보조제로서의 이 화합물의 용도 | |
| IE49805B1 (en) | Blasting composition | |
| CA1339057C (fr) | Composition explosive | |
| Sabri et al. | Tuning particle–particle interactions to control Pickering emulsions constituents separation | |
| EP0327205A1 (fr) | Obtention d'aspect mousseux de compositions explosives en émulsion par voie chimique | |
| CA2030169C (fr) | Explosif a emulsion | |
| US5336343A (en) | Vinyl ethers as nonammonia producing bonding agents in composite propellant formulations | |
| US4521352A (en) | Microencapsulation process | |
| US4908080A (en) | Water-in-oil type emulsion explosive with chelating agent | |
| US4063975A (en) | Colored composition of explosives | |
| US3067076A (en) | Stabilized ammonium nitrate propellant | |
| US3361680A (en) | Use of ultrasonic vibrations to disperse a liquid in another liquid | |
| CA1037719A (fr) | Epaississant pour systemes explosifs a solvant | |
| US3000720A (en) | Desensitization of cyclotrimethylenetrinitramine with dinitroethylbenzene | |
| JPH0524887B2 (fr) | ||
| US2832721A (en) | Vitamin emulsions | |
| RU2639146C1 (ru) | Катализатор скорости горения на основе продукта ОСФ | |
| RU96112495A (ru) | Способ приготовления взрывчатого вещества | |
| RU2755074C2 (ru) | Эмульгатор для промышленных эмульсионных взрывчатых веществ | |
| US3471344A (en) | Thixotropic organic liquid propellant compositions with solid storage characteristics | |
| US2400120A (en) | Phosphatide composition and method of preparing | |
| SU1562348A1 (ru) | Реагент дл обработки бурового раствора |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AK | Designated states |
Kind code of ref document: A1 Designated state(s): CA DE GB HU KR RU UA US |
|
| AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE |
|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| 122 | Ep: pct application non-entry in european phase | ||
| REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |