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WO1998044115A3 - Regulateurs du processus de signalement de la proteine g - Google Patents

Regulateurs du processus de signalement de la proteine g Download PDF

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Publication number
WO1998044115A3
WO1998044115A3 PCT/US1998/006336 US9806336W WO9844115A3 WO 1998044115 A3 WO1998044115 A3 WO 1998044115A3 US 9806336 W US9806336 W US 9806336W WO 9844115 A3 WO9844115 A3 WO 9844115A3
Authority
WO
WIPO (PCT)
Prior art keywords
rgps
regulators
provides
protein signalling
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1998/006336
Other languages
English (en)
Other versions
WO1998044115A2 (fr
Inventor
Jennifer L Hillman
Surya K Goli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Priority to AU67908/98A priority Critical patent/AU6790898A/en
Publication of WO1998044115A2 publication Critical patent/WO1998044115A2/fr
Publication of WO1998044115A3 publication Critical patent/WO1998044115A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne deux régulateurs du processus de signalement de la protéine G (appelés individuellement RGPS-1 et RGPS-2, et collectivement RGPS) et des polypeptides identifiant et codant RGPS. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des agonistes, des anticorps et des antagonistes, ainsi que des procédés de production de RGPS, et des procédés de traitement ou de prévention des pathologies associées à l'expression de RGPS.
PCT/US1998/006336 1997-03-31 1998-03-31 Regulateurs du processus de signalement de la proteine g Ceased WO1998044115A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU67908/98A AU6790898A (en) 1997-03-31 1998-03-31 Regulators of g-protein signalling

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/829,110 US5882890A (en) 1997-03-31 1997-03-31 Nucleic acids encoding novel regulators of G-protein signaling
US08/829,110 1997-03-31

Publications (2)

Publication Number Publication Date
WO1998044115A2 WO1998044115A2 (fr) 1998-10-08
WO1998044115A3 true WO1998044115A3 (fr) 1998-12-30

Family

ID=25253553

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/006336 Ceased WO1998044115A2 (fr) 1997-03-31 1998-03-31 Regulateurs du processus de signalement de la proteine g

Country Status (3)

Country Link
US (1) US5882890A (fr)
AU (1) AU6790898A (fr)
WO (1) WO1998044115A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274362B1 (en) 1999-02-04 2001-08-14 Millennium Pharmaceuticals, Inc. RGS-containing molecules and uses thereof
WO2001021797A1 (fr) * 1999-09-21 2001-03-29 Forsyth Dental Infirmary For Children Rgs10b, regulateur de proteine g exprime dans les osteoclastes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996038462A1 (fr) * 1995-06-02 1996-12-05 Massachusetts Institute Of Technology Regulateurs de la signalisation de proteines g

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996038462A1 (fr) * 1995-06-02 1996-12-05 Massachusetts Institute Of Technology Regulateurs de la signalisation de proteines g

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Emest4 Database Entry Hs046238 Accession number H70046; 25 October 1995 HILLIER L. ET AL.:"The WashU-Merck EST Project" *
Emhum1 Database Entry Af030107 Accession number AF030107; 14 November 1997 CHATERJEE T.K. ET AL.:"Molecular cloning of human RGS13 cDNA" *
KIRK M. DRUEY ET AL.: "Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family", NATURE, vol. 379, no. 6567, 22 February 1996 (1996-02-22), LONDON GB, pages 742 - 746, XP002058369 *
Trhum Database Entry O14921; Accession number O14921; 1 January 1998 CHATERJEE T.K. ET AL. *

Also Published As

Publication number Publication date
WO1998044115A2 (fr) 1998-10-08
US5882890A (en) 1999-03-16
AU6790898A (en) 1998-10-22

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