WO1997033640B1 - Dosage counter for metered dose inhaler (mdi) systems using a miniature pressure sensor - Google Patents
Dosage counter for metered dose inhaler (mdi) systems using a miniature pressure sensorInfo
- Publication number
- WO1997033640B1 WO1997033640B1 PCT/US1997/003478 US9703478W WO9733640B1 WO 1997033640 B1 WO1997033640 B1 WO 1997033640B1 US 9703478 W US9703478 W US 9703478W WO 9733640 B1 WO9733640 B1 WO 9733640B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- transfer passage
- pressure sensor
- passage
- transfer
- pressure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Abstract
A method and apparatus for directly counting the number of doses expended from a Metered Dose Inhaler (MDI) medicinal delivery system. A miniature pressure sensor and microprocessor is used to detect the pressure pulse in the transfer channel of the mouthpiece of the MDI through which the inhaler dose (the prescribed mixture of aerosol propellant and medicinal drug) is released. The microprocessor processes data reflecting the dynamics of the pressure pulse and counts the number of doses administered. The microprocessor displays the counted doses (or doses remaining) on a miniature digital display. Additional information also may be provided to a user from the display or via an audible signal.
Claims
AMENDED CLAIMS
[received by the International Bureau on 8 September 1997 (08.09.97) ; new claims 21 -27 added ; remaining claims unchanged ( 1 page ) ]
21. The drug dispensing apparatus as set forth in claim 1 wherein said pressure sensor is external to said transfer passage and isolated from a metered dose in said transfer passage by a sealing structure.
22. The drug dispensing apparatus as set forth in claim 21 wherein said sealing structure comprises a protective gel.
23. The drug dispensing apparatus as set forth in claim 1 wherein said delivery apparatus comprises a hole extending between an external location for said pressure sensor and said transfer passage, said hole being sealed at said transfer passage by a sealing means.
24. The drug dispensing apparatus as set forth in claim 12 wherein said pressure sensor in external to and isolated from a metered dose in said transfer passage by a sealing structure.
25. The drug dispensing apparatus as set forth in claim 24 wherein said sealing structure comprises a protective gel.
26. The drug dispensing apparatus as set forth in claim 12 wherein said body comprises a hole extending between as extermal location for said pressure sensor and said transfer passage, said hole being sealed at said transfer passage by a sealing means.
27. The method of monitoring as recited in claim 15 comprising:
disposing a pressure sensor in an operaticely adjacent and dose-isolated pesition with respect to said transfer passage.
STATEMENT UNDER ARHCLE 19
The original disclosure taught the use of a pressure sensor with its sensing structure within a hole extending to the transfer channel 7 and a protective gel to cover the sensor for protection and appropriate interface with the channel e . g . , one that does not increase the colume of the channel . The new claims are directed to the originally disclosed invention , whivh broadly contemplates a protective sealing of the pressure sensor by any of a variety of structures known to one of ordinary skill in the art .
All of the claims as originally filed and as newly added herein are patentable over the cited art . In particular , none of the prior the is related to the simple structure found in the present invention which measures a "predetermined pressure" existing in the "transfer passage" , the "predetermined pressure" being defined as substantially the pressure formed at the exit nozzle of a pressurized container by a metered dose.
With respect to the Medtrac Reference (WO 95/ 07723 ) , where air passage 515 exposes the sensor to ambient air and further provides an increased volume in the pressure measuremnet passage , by definition , such the 'predetermined pressure" required by the claim would not be found .
With respect to each of the British Application (GB 2 294 402 A) and the European Application (0 667 168 A), there is no measurement of pressure in a transfer passage. Specifically, in the claimed invention, the measurement that results in a detection of a change in the "predetermined pressure" is within a "transfer" passage, that is one which serves to transfer the metered discharge directly to the delivery passage and the patient upon actuation of the MDI. In the British Application, the passage 4 prior to a holding chamber 1 that holds the discharge until inhaled by a patient is not such transfer passage. Furthermore, the claimed invention is not an inhalation training device, as in the European Appkucation (0 667 168 A).
The addition of new claims 21-27 are supported by and do not go beyond the disclosure in the International application as field.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU20688/97A AU2068897A (en) | 1996-03-14 | 1997-03-13 | Dosage counter for metered dose inhaler (mdi) systems using a miniature pressure sensor |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/616,152 | 1996-03-14 | ||
| US08/616,152 US5676129A (en) | 1996-03-14 | 1996-03-14 | Dosage counter for metered dose inhaler (MDI) systems using a miniature pressure sensor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1997033640A1 WO1997033640A1 (en) | 1997-09-18 |
| WO1997033640B1 true WO1997033640B1 (en) | 1997-10-23 |
Family
ID=24468258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1997/003478 Ceased WO1997033640A1 (en) | 1996-03-14 | 1997-03-13 | Dosage counter for metered dose inhaler (mdi) systems using a miniature pressure sensor |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US5676129A (en) |
| AU (1) | AU2068897A (en) |
| WO (1) | WO1997033640A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9008761B2 (en) | 2010-02-01 | 2015-04-14 | Proteus Digital Health, Inc. | Two-wrist data gathering system |
Families Citing this family (117)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6108635A (en) * | 1996-05-22 | 2000-08-22 | Interleukin Genetics, Inc. | Integrated disease information system |
| US5881723A (en) | 1997-03-14 | 1999-03-16 | Nellcor Puritan Bennett Incorporated | Ventilator breath display and graphic user interface |
| TW533865U (en) * | 1997-06-10 | 2003-05-21 | Glaxo Group Ltd | Dispenser for dispensing medicament and actuation indicating device |
| US6142339A (en) | 1998-01-16 | 2000-11-07 | 1263152 Ontario Inc. | Aerosol dispensing device |
| AU753568B2 (en) | 1998-01-16 | 2002-10-24 | Trudell Medical International | Indicating device for use with a dispensing device |
| US6358058B1 (en) * | 1998-01-30 | 2002-03-19 | 1263152 Ontario Inc. | Aerosol dispensing inhaler training device |
| US6336453B1 (en) | 1999-04-30 | 2002-01-08 | Trudell Medical International | Indicating device for aerosol container |
| US6729330B2 (en) | 1998-05-05 | 2004-05-04 | Trudell Medical International | Indicating device for aerosol container |
| US6082358A (en) | 1998-05-05 | 2000-07-04 | 1263152 Ontario Inc. | Indicating device for aerosol container |
| US6260549B1 (en) * | 1998-06-18 | 2001-07-17 | Clavius Devices, Inc. | Breath-activated metered-dose inhaler |
| US6651651B1 (en) | 1998-08-28 | 2003-11-25 | Smithkline Beecham Corporation | Dispenser |
| US6223744B1 (en) * | 1999-03-16 | 2001-05-01 | Multi-Vet Ltd. | Wearable aerosol delivery apparatus |
| GB0003839D0 (en) * | 2000-02-19 | 2000-04-05 | Glaxo Group Ltd | Housing for an inhaler |
| US6701928B2 (en) | 2000-04-06 | 2004-03-09 | Wake Forest University | Inhaler dispensing system adapters for laryngectomized subjects and associated methods |
| WO2002030497A1 (en) * | 2000-10-09 | 2002-04-18 | Siemens Aktiengesellschaft | Medicament dispenser |
| US6745760B2 (en) | 2001-05-15 | 2004-06-08 | Trudell Medical International | Medicament applicator |
| DE10146815B4 (en) * | 2001-09-18 | 2005-05-04 | Ing. Erich Pfeiffer Gmbh | Donor for media |
| US7255102B2 (en) * | 2002-02-01 | 2007-08-14 | Generex Pharmaceuticals Inc. | Metered dose spray device for use with macromolecular pharmaceutical agents such as insulin |
| US6651844B2 (en) | 2002-02-22 | 2003-11-25 | Schering Corporation | Spray dispenser counter |
| US7004164B2 (en) | 2002-03-21 | 2006-02-28 | Trudell Medical International | Indicating device for aerosol container |
| US6830046B2 (en) | 2002-04-29 | 2004-12-14 | Hewlett-Packard Development Company, L.P. | Metered dose inhaler |
| US6691058B2 (en) * | 2002-04-29 | 2004-02-10 | Hewlett-Packard Development Company, L.P. | Determination of pharmaceutical expiration date |
| US6857427B2 (en) * | 2002-09-04 | 2005-02-22 | Ric Investments, Inc. | Interactive character for use with an aerosol medication delivery system |
| CN100403472C (en) * | 2003-02-18 | 2008-07-16 | 三洋电机株式会社 | Electronic digital pressure switch |
| WO2004078236A2 (en) * | 2003-03-04 | 2004-09-16 | Norton Healthcare Limited | Medicament dispensing device with a display indicative of the state of an internal medicament reservoir |
| US20050028815A1 (en) * | 2003-07-23 | 2005-02-10 | Deaton Daniel M. | Apparatus for electronic dosage counter |
| US20050172958A1 (en) * | 2003-08-20 | 2005-08-11 | The Brigham And Women's Hospital, Inc. | Inhalation device and system for the remote monitoring of drug administration |
| GB2398065A (en) * | 2003-10-16 | 2004-08-11 | Bespak Plc | Dispensing apparatus |
| FR2861460B1 (en) * | 2003-10-28 | 2007-03-09 | Valois Sas | DEVICE FOR SPRAYING FLUID PRODUCT. |
| US7621273B2 (en) | 2003-10-28 | 2009-11-24 | Trudell Medical International | Indicating device with warning dosage indicator |
| US7100530B2 (en) | 2003-12-15 | 2006-09-05 | Trudell Medical International, Inc. | Dose indicating device |
| FR2864231B1 (en) * | 2003-12-19 | 2006-05-19 | Valois Sas | DEVICE FOR DISPENSING FLUID PRODUCT |
| US7481213B2 (en) * | 2004-02-11 | 2009-01-27 | Hewlett-Packard Development Company, L.P. | Medicament dispenser |
| US7467630B2 (en) * | 2004-02-11 | 2008-12-23 | Hewlett-Packard Development Company, L.P. | Medicament dispenser |
| US7543582B2 (en) | 2004-09-20 | 2009-06-09 | Trudell Medical International | Dose indicating device with display elements attached to container |
| FR2879482B1 (en) * | 2004-12-20 | 2007-03-30 | Oreal | DEVICE FOR SPRAYING A PRODUCT, IN PARTICULAR A FRAGRANCE |
| US7832394B2 (en) * | 2004-12-22 | 2010-11-16 | Schechter Alan M | Apparatus for dispensing pressurized contents |
| MX2007008752A (en) | 2005-01-20 | 2007-08-14 | Trudell Medical Int | Dispensing device. |
| EP1893261A1 (en) * | 2005-05-12 | 2008-03-05 | Kos Life Sciences, Inc. | Dose counter for metered dose inhalers |
| JP5295769B2 (en) | 2005-08-31 | 2013-09-18 | ティツー・バイオシステムズ・インコーポレーテッド | NMR apparatus for detecting analytes |
| US8021310B2 (en) | 2006-04-21 | 2011-09-20 | Nellcor Puritan Bennett Llc | Work of breathing display for a ventilation system |
| US20070295329A1 (en) * | 2006-06-13 | 2007-12-27 | Lieberman Eric A | Dose indicator |
| EP2037999B1 (en) | 2006-07-07 | 2016-12-28 | Proteus Digital Health, Inc. | Smart parenteral administration system |
| DE102006032293A1 (en) * | 2006-07-11 | 2008-01-24 | Friedrich Sanner Gmbh & Co. Kg | Device for the metered delivery of sprayable substances |
| US8141550B2 (en) | 2006-08-01 | 2012-03-27 | Trudell Medical International | Dispensing device |
| US7784461B2 (en) | 2006-09-26 | 2010-08-31 | Nellcor Puritan Bennett Llc | Three-dimensional waveform display for a breathing assistance system |
| US20080110453A1 (en) * | 2006-11-15 | 2008-05-15 | Delphi Technologies Inc. | Nebulizer and methods for controlling the nebulizer |
| WO2008067254A2 (en) * | 2006-11-27 | 2008-06-05 | Abbott Respiratory Llc | Nasal drug delivery device and method |
| FR2910254B1 (en) * | 2006-12-20 | 2009-04-17 | Oreal | PIEZOELECTRIC SPRAY SYSTEM AND CORRESPONDING REFILL |
| FR2910253B1 (en) * | 2006-12-20 | 2010-03-12 | Oreal | METHOD FOR DISPENSING A PRODUCT SPRAYED BY A PIEZOELECTRIC SPRAY SYSTEM AND A SPRAY SYSTEM FOR IMPLEMENTING SUCH A METHOD |
| US20080210231A1 (en) * | 2007-01-31 | 2008-09-04 | Abbott Laboratories | Metered dose inhaler cleaning method and apparatus |
| WO2008112353A2 (en) * | 2007-02-05 | 2008-09-18 | The Brigham And Women's Hospital, Inc. | Instrumented metered-dose inhaler and methods for predicting disease exacerbations |
| EP2157992B1 (en) | 2007-06-15 | 2016-12-14 | iDTx Systems, Inc. | A drug delivery and monitoring system for a ventilator |
| WO2009046215A2 (en) * | 2007-10-02 | 2009-04-09 | Lab International Srl | Safety and abuse deterrent improved device |
| JP5243548B2 (en) | 2007-10-25 | 2013-07-24 | プロテウス デジタル ヘルス， インコーポレイテッド | Fluid communication port for information systems |
| US8419638B2 (en) | 2007-11-19 | 2013-04-16 | Proteus Digital Health, Inc. | Body-associated fluid transport structure evaluation devices |
| US8082873B2 (en) | 2008-05-05 | 2011-12-27 | Trudell Medical International | Drive mechanism for an indicating device |
| US8181591B1 (en) | 2008-05-23 | 2012-05-22 | Trudell Medical International | Domed actuator for indicating device |
| EP2179760B1 (en) | 2008-10-22 | 2013-02-27 | Trudell Medical International | Modular Aerosol Delivery System |
| GB2469068B (en) * | 2009-03-31 | 2011-03-09 | Naseem Bari | Usage indicator |
| GB2470188B (en) * | 2009-05-11 | 2011-06-22 | Consort Medical Plc | Improvements in or relating to dispensing apparatus and dose counters |
| US20110031038A1 (en) * | 2009-08-07 | 2011-02-10 | Sagatulo, Inc. | Method and device for indicating doses in a drug delivery system |
| US8539945B2 (en) | 2009-08-18 | 2013-09-24 | Teva Pharmaceutical Industries Ltd. | Dose counter and recording method |
| GB2473070B (en) * | 2009-09-01 | 2011-09-28 | Consort Medical Plc | Dispensing apparatus |
| FR2952042B1 (en) * | 2009-11-03 | 2012-01-20 | Valois Sas | DEVICE FOR DISPENSING FLUID PRODUCT. |
| US8335992B2 (en) | 2009-12-04 | 2012-12-18 | Nellcor Puritan Bennett Llc | Visual indication of settings changes on a ventilator graphical user interface |
| US8924878B2 (en) | 2009-12-04 | 2014-12-30 | Covidien Lp | Display and access to settings on a ventilator graphical user interface |
| US9119925B2 (en) | 2009-12-04 | 2015-09-01 | Covidien Lp | Quick initiation of respiratory support via a ventilator user interface |
| US9262588B2 (en) | 2009-12-18 | 2016-02-16 | Covidien Lp | Display of respiratory data graphs on a ventilator graphical user interface |
| US8499252B2 (en) | 2009-12-18 | 2013-07-30 | Covidien Lp | Display of respiratory data graphs on a ventilator graphical user interface |
| CA2788336C (en) | 2010-02-01 | 2018-05-01 | Proteus Digital Health, Inc. | Data gathering system |
| US8869793B1 (en) | 2010-05-18 | 2014-10-28 | Idtx Systems, Inc. | Compact self-contained automated MDI adapters or units for ventilators |
| DE102010024912B4 (en) | 2010-06-15 | 2013-02-28 | Aptar Radolfzell Gmbh | inhalator |
| US8915869B2 (en) | 2011-01-10 | 2014-12-23 | Bioguidance Llc | Patient monitoring device |
| US8827930B2 (en) | 2011-01-10 | 2014-09-09 | Bioguidance Llc | System and method for patient monitoring |
| DE102011007008B4 (en) * | 2011-04-07 | 2015-08-06 | Aptar Radolfzell Gmbh | media dispenser |
| US10362967B2 (en) | 2012-07-09 | 2019-07-30 | Covidien Lp | Systems and methods for missed breath detection and indication |
| WO2014204511A2 (en) | 2013-06-18 | 2014-12-24 | Isonea Limited | Compliance monitoring for asthma inhalers |
| DE102013214601B3 (en) | 2013-07-25 | 2014-05-22 | Aptar Radolfzell Gmbh | Housing for container unit of inhalation device e.g. metered-dose inhaler, for oral administration of pharmaceutical medium, has membrane reversibly deformed based on pressure in pressure chamber and acting together with pushbutton |
| US11424017B2 (en) | 2013-10-19 | 2022-08-23 | Aptargroup, Inc. | Respiratory system and method that monitors medication flow |
| US10019555B2 (en) | 2013-10-19 | 2018-07-10 | Cohero Health, Inc. | Interactive respiratory device usage tracking system |
| DE102014206350B3 (en) * | 2014-04-02 | 2015-05-21 | Aptar Radolfzell Gmbh | Pharmaceutical dispenser with a detection device |
| US10173025B2 (en) | 2014-04-21 | 2019-01-08 | Idtx Systems, Inc. | Automated drug delivery systems |
| US9581586B2 (en) * | 2014-05-16 | 2017-02-28 | The Regents Of The University Of California | Approach to asthma inhaler compliance using breath measurement of tetrafluoroethane |
| ES2952510T3 (en) | 2014-06-30 | 2023-10-31 | Proveris Scient Corporation | Sampling apparatus for determining the quantity and uniformity of an administered dose of medication and related methods |
| FR3024655B1 (en) * | 2014-08-06 | 2025-10-10 | Nemera La Verpilliere | PHARMACEUTICAL PREPARATION DISPENSING DEVICE |
| US9950129B2 (en) | 2014-10-27 | 2018-04-24 | Covidien Lp | Ventilation triggering using change-point detection |
| US10561814B2 (en) | 2014-11-19 | 2020-02-18 | Idtx Systems, Inc. | Automated drug dispensing systems with automated HME bypass for ventilator circuits |
| JP6818008B2 (en) | 2015-07-20 | 2021-01-20 | パール セラピューティクス，インコーポレイテッド | Aerosol delivery system and related methods |
| EP3175876A1 (en) * | 2015-12-01 | 2017-06-07 | Carebay Europe Ltd. | Medicament delivery device with user feedback capability |
| WO2017127731A1 (en) | 2016-01-21 | 2017-07-27 | T2 Biosystems, Inc. | Nmr methods and systems for the rapid detection of bacteria |
| CA3016890A1 (en) * | 2016-03-09 | 2017-09-14 | Proveris Scientific Corporation | Methods for measuring dose content uniformity performance of inhaler and nasal devices |
| CN109152891B (en) | 2016-03-24 | 2022-11-08 | 特鲁德尔医学国际公司 | Respiratory care system with electronic indicator |
| US10850050B2 (en) | 2016-05-19 | 2020-12-01 | Trudell Medical International | Smart valved holding chamber |
| CA3024721A1 (en) | 2016-05-19 | 2017-11-23 | Mannkind Corporation | Apparatus, system and method for detecting and monitoring inhalations |
| ES2988939T3 (en) | 2016-07-08 | 2024-11-22 | Trudell Medical Int Inc | Intelligent Oscillating Positive Expiratory Pressure Device |
| EP3471805B1 (en) * | 2016-11-18 | 2019-09-04 | Norton (Waterford) Limited | Drug delivery device with electronics |
| CA3036631C (en) | 2016-12-09 | 2025-09-23 | Trudell Medical Int | SMART NEBULIZER |
| US11471608B2 (en) | 2017-08-21 | 2022-10-18 | Eli Lilly And Company | Medication delivery device with sensing system |
| EP4585247A3 (en) | 2018-01-04 | 2025-07-23 | Trudell Medical International Inc. | Smart oscillating positive expiratory pressure device |
| US11590299B1 (en) * | 2018-05-13 | 2023-02-28 | Keith Good | Methods and systems for metered dose inhalation monitoring and communication |
| JP7427660B2 (en) | 2018-06-04 | 2024-02-05 | トゥルーデル メディカル インターナショナル | Holding chamber with smart valve |
| AU2018264051B2 (en) | 2018-08-09 | 2020-03-26 | Final Bell Brand Co. | A vaporization device, method of using the device, a charging case, a kit, and a vibration assembly |
| TWI888357B (en) | 2018-08-22 | 2025-07-01 | 美商奎諾維亞公司 | Electronic device for creating an aerosol for inhalation by a person |
| CA3131563A1 (en) | 2019-02-27 | 2020-09-03 | Eli Lilly And Company | Medication delivery device with sensing system |
| CA3160698A1 (en) * | 2019-02-27 | 2020-09-03 | Jay Mark FRIEDLANDER | Medication delivery device with sensing system |
| EP3701987B1 (en) * | 2019-02-28 | 2021-06-09 | Aptar Radolfzell GmbH | Pharmaceutical dispenser, in particular inhaler |
| US20220218926A1 (en) * | 2019-05-07 | 2022-07-14 | Kindeva Drug Delivery L.P. | Inhaler and method of detecting obstruction |
| WO2021038467A1 (en) | 2019-08-27 | 2021-03-04 | Trudell Medical International | Smart oscillating positive expiratory pressure device |
| US20210113783A1 (en) | 2019-10-20 | 2021-04-22 | Respira Technologies, Inc. | Electronic devices and liquids for aerosolizing and inhaling therewith |
| CA3162232A1 (en) * | 2019-11-21 | 2021-05-27 | Juul Labs, Inc. | Vaporizer device dose consumption configurations |
| CA3161873A1 (en) | 2019-12-10 | 2021-06-17 | Trudell Medical International | Integrated dose counter |
| FR3108536B1 (en) * | 2020-03-30 | 2022-06-17 | Aptar France Sas | Fluid product dispensing device, in particular for a limited number of doses |
| US11672934B2 (en) | 2020-05-12 | 2023-06-13 | Covidien Lp | Remote ventilator adjustment |
| US12471625B2 (en) | 2020-11-01 | 2025-11-18 | Qnovia, Inc. | Electronic devices and liquids for aerosolizing and inhaling therewith |
| US12279650B2 (en) | 2022-04-22 | 2025-04-22 | Qnovia, Inc. | Electronic devices for aerosolizing and inhaling liquid having an enclosed interior air passageway with diaphragm and pressure sensor |
| EP4275728A1 (en) * | 2022-05-10 | 2023-11-15 | Findair Sp. z o. o. | An actuator for an inhaler |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5020527A (en) * | 1990-02-20 | 1991-06-04 | Texax-Glynn Corporation | Inhaler device with counter/timer means |
| WO1994016759A1 (en) * | 1991-03-05 | 1994-08-04 | Miris Medical Corporation | An automatic aerosol medication delivery system and methods |
| US5404871A (en) * | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
| US5450336A (en) * | 1991-03-05 | 1995-09-12 | Aradigm Corporation | Method for correcting the drift offset of a transducer |
| US5392768A (en) * | 1991-03-05 | 1995-02-28 | Aradigm | Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval |
| US5363842A (en) * | 1991-12-20 | 1994-11-15 | Circadian, Inc. | Intelligent inhaler providing feedback to both patient and medical professional |
| US5284133A (en) * | 1992-07-23 | 1994-02-08 | Armstrong Pharmaceuticals, Inc. | Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means |
| US5373851A (en) * | 1993-04-19 | 1994-12-20 | Brunswick Biomedical Corporation | Specialized peak flow meter |
| WO1995007723A1 (en) * | 1993-09-16 | 1995-03-23 | Medtrac Technologies Inc. | Inhaler having an attachable dosing monitor and recorder |
| US5411173A (en) * | 1993-12-17 | 1995-05-02 | Weinstein; Albert | Counter attachment for product dispensers |
| EP0667168B1 (en) * | 1994-02-14 | 2000-06-21 | Aradigm Corporation | An inhalation training device |
| US5482030A (en) * | 1994-06-13 | 1996-01-09 | Klein; David | Aerosol and non-aerosol spray counter |
| GB9421687D0 (en) * | 1994-10-27 | 1994-12-14 | Aid Medic Ltd | Dosimetric spacer |
-
1996
- 1996-03-14 US US08/616,152 patent/US5676129A/en not_active Expired - Fee Related
-
1997
- 1997-03-13 AU AU20688/97A patent/AU2068897A/en not_active Abandoned
- 1997-03-13 WO PCT/US1997/003478 patent/WO1997033640A1/en not_active Ceased
- 1997-08-29 US US08/921,389 patent/US6138669A/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9008761B2 (en) | 2010-02-01 | 2015-04-14 | Proteus Digital Health, Inc. | Two-wrist data gathering system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO1997033640B1 (en) | Dosage counter for metered dose inhaler (mdi) systems using a miniature pressure sensor | |
| US5794612A (en) | MDI device with ultrasound sensor to detect aerosol dispensing | |
| EP0940154A3 (en) | Device for delivering aerosolized medicaments | |
| EP0681491B1 (en) | Intrapulmonary delivery of hormones | |
| US6138669A (en) | Dosage counter for metered dose inhaler (MDI) systems using a miniature pressure sensor | |
| CA2378713A1 (en) | Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments | |
| AU701769B2 (en) | Casing and spirometer for metered dose inhaler | |
| US5509404A (en) | Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values | |
| US6085742A (en) | Intrapulmonary delivery device | |
| CA1255558A (en) | Method of dispensing and/or a dispenser | |
| US20060254581A1 (en) | Dose counting in metered dose inhaler | |
| EP0363060A3 (en) | Aerosol inhaler | |
| LTIP340A (en) | Inhalation device | |
| WO2000054828B1 (en) | Wearable aerosol delivery apparatus | |
| DE69503487D1 (en) | SOLID METER FOR DOSING INHALATOR | |
| IL316543A (en) | Compliance Monitoring Unit for Inhaler | |
| KR20030058937A (en) | Pre-metered dose magazine for breath-actuated dry powder inhaler | |
| CA2203805A1 (en) | Dosimetric spacer | |
| KR20170047321A (en) | Tidal dry powder inhaler with miniature pressure sensor activation | |
| ATE374054T1 (en) | BREATHING ACTUATED INHALER | |
| US11801352B2 (en) | Devices and control systems for inhaled drugs | |
| US20080060643A1 (en) | Inhaler Device that Reduces the Risk for Miscounting a Dosage | |
| US20070272764A1 (en) | Fluid Product Spraying Device | |
| EP0013534A1 (en) | Inhalation device | |
| CA2235005A1 (en) | Powder inhaler |