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WO1997030085B1 - Sous-unites et fragments de troponine utiles comme inhibiteurs de l'angiogenese - Google Patents

Sous-unites et fragments de troponine utiles comme inhibiteurs de l'angiogenese

Info

Publication number
WO1997030085B1
WO1997030085B1 PCT/US1997/002439 US9702439W WO9730085B1 WO 1997030085 B1 WO1997030085 B1 WO 1997030085B1 US 9702439 W US9702439 W US 9702439W WO 9730085 B1 WO9730085 B1 WO 9730085B1
Authority
WO
WIPO (PCT)
Prior art keywords
fact
troponin subunit
peptide
subunit
human
Prior art date
Application number
PCT/US1997/002439
Other languages
English (en)
Other versions
WO1997030085A1 (fr
Filing date
Publication date
Priority claimed from US08/602,941 external-priority patent/US5837680A/en
Application filed filed Critical
Priority to JP52953997A priority Critical patent/JP3990456B2/ja
Priority to EP97905992A priority patent/EP1007556B1/fr
Priority to AT97905992T priority patent/ATE266675T1/de
Priority to AU22753/97A priority patent/AU707262B2/en
Priority to DE69729125T priority patent/DE69729125T2/de
Priority to CA2247247A priority patent/CA2247247C/fr
Publication of WO1997030085A1 publication Critical patent/WO1997030085A1/fr
Publication of WO1997030085B1 publication Critical patent/WO1997030085B1/fr

Links

Abstract

Des procédés permettent d'inhiber l'angiogénèse atopique à l'aide de sous-unités de troponine et de leurs fragments peptidiques. On décrit aussi des compositions pharmaceutiques comprenant une sous-unité de troponine ou un de ses fragments. Ces compositions et procédés permettent de traiter des tumeurs solides, particulièrement celles du système nerveux central et de l'oeil.
PCT/US1997/002439 1996-02-16 1997-02-14 Sous-unites et fragments de troponine utiles comme inhibiteurs de l'angiogenese WO1997030085A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP52953997A JP3990456B2 (ja) 1996-02-16 1997-02-14 血管形成の阻害剤として有用なトロポニンのサブユニットおよびフラグメント
EP97905992A EP1007556B1 (fr) 1996-02-16 1997-02-14 Sous-unites et fragments de troponine utiles comme inhibiteurs de l'angiogenese
AT97905992T ATE266675T1 (de) 1996-02-16 1997-02-14 Troponin untereinheiten und fragmente zur verwendung als inhibitoren der angiogenese
AU22753/97A AU707262B2 (en) 1996-02-16 1997-02-14 Troponin subunits and fragments useful as angiogenesis inhibitors
DE69729125T DE69729125T2 (de) 1996-02-16 1997-02-14 Troponin untereinheiten und fragmente zur verwendung als inhibitoren der angiogenese
CA2247247A CA2247247C (fr) 1996-02-16 1997-02-14 Sous-unites et fragments de troponine utiles comme inhibiteurs de l'angiogenese

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/602,941 1996-02-16
US08/602,941 US5837680A (en) 1996-02-16 1996-02-16 Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis

Publications (2)

Publication Number Publication Date
WO1997030085A1 WO1997030085A1 (fr) 1997-08-21
WO1997030085B1 true WO1997030085B1 (fr) 1997-09-25

Family

ID=24413387

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/002439 WO1997030085A1 (fr) 1996-02-16 1997-02-14 Sous-unites et fragments de troponine utiles comme inhibiteurs de l'angiogenese

Country Status (8)

Country Link
US (4) US5837680A (fr)
EP (1) EP1007556B1 (fr)
JP (1) JP3990456B2 (fr)
AT (1) ATE266675T1 (fr)
AU (1) AU707262B2 (fr)
CA (1) CA2247247C (fr)
DE (1) DE69729125T2 (fr)
WO (1) WO1997030085A1 (fr)

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DE60333004D1 (de) * 2002-02-04 2010-07-29 Yoshida Hideo Antikrebsmittel mit verotoxinvarianten
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AU2003213730A1 (en) 2002-03-01 2003-09-16 Bracco International B.V. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
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WO2004028559A1 (fr) * 2002-09-26 2004-04-08 The Board Of Trustees Of The University Of Illinois Fragments anti-angiogeniques du facteur derive de l'epithelium pigmentaire (pedf)
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US5837680A (en) * 1996-02-16 1998-11-17 Children's Medical Center Corporation Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis

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