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WO1997029194A3 - Herstellung von l-ascorbinsäure - Google Patents

Herstellung von l-ascorbinsäure Download PDF

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Publication number
WO1997029194A3
WO1997029194A3 PCT/EP1997/000461 EP9700461W WO9729194A3 WO 1997029194 A3 WO1997029194 A3 WO 1997029194A3 EP 9700461 W EP9700461 W EP 9700461W WO 9729194 A3 WO9729194 A3 WO 9729194A3
Authority
WO
WIPO (PCT)
Prior art keywords
ascorbic acid
preparation
enzymes
codes
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1997/000461
Other languages
English (en)
French (fr)
Other versions
WO1997029194A2 (de
Inventor
Ralf Mattes
Heidrun Schmidt
Klaus-Dieter Kulbe
Gernot Miemietz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Herbstreith und Fox KG Pektin Fabriken
Original Assignee
Herbstreith und Fox KG Pektin Fabriken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Herbstreith und Fox KG Pektin Fabriken filed Critical Herbstreith und Fox KG Pektin Fabriken
Priority to EP97901626A priority Critical patent/EP0879287A2/de
Publication of WO1997029194A2 publication Critical patent/WO1997029194A2/de
Publication of WO1997029194A3 publication Critical patent/WO1997029194A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Sustainable Development (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Die Erfindung betrifft ein neues Verfahren zur Synthese von L-Ascorbinsäure, für dieses Verfahren geeignete rekombinante Enzyme und die für die Enzyme kodierende Nucleinsäure.
PCT/EP1997/000461 1996-02-09 1997-02-03 Herstellung von l-ascorbinsäure Ceased WO1997029194A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP97901626A EP0879287A2 (de) 1996-02-09 1997-02-03 Herstellung von l-ascorbinsäure

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19604798.6 1996-02-09
DE19604798A DE19604798A1 (de) 1996-02-09 1996-02-09 Herstellung von L-Ascorbinsäure

Publications (2)

Publication Number Publication Date
WO1997029194A2 WO1997029194A2 (de) 1997-08-14
WO1997029194A3 true WO1997029194A3 (de) 1997-10-02

Family

ID=7784990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1997/000461 Ceased WO1997029194A2 (de) 1996-02-09 1997-02-03 Herstellung von l-ascorbinsäure

Country Status (3)

Country Link
EP (1) EP0879287A2 (de)
DE (1) DE19604798A1 (de)
WO (1) WO1997029194A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105671106B (zh) * 2016-02-16 2021-06-11 珀莱雅化妆品股份有限公司 一种采用橄榄油发酵法制备鞘糖脂的方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1026257B1 (de) * 1999-01-18 2006-04-12 DSM IP Assets B.V. Herstellung von L-Ascorbinsäure und D-Erythorbinsäure
ATE323172T1 (de) * 1999-01-18 2006-04-15 Dsm Ip Assets Bv Herstellung von l-ascorbinsäure und d- erythorbinsäure
FI20055263A0 (fi) * 2005-05-30 2005-05-30 Valtion Teknillinen Sokerihappojen mikrobinen muuttaminen ja siihen soveltuvia välineitä
WO2009145838A2 (en) * 2008-04-04 2009-12-03 Massachusetts Institute Of Technology Cellular production of glucaric acid
US20130289276A1 (en) * 2010-10-08 2013-10-31 Cadila Healthcare Limited Process for preparing an intermediate of sitagliptin via enzymatic conversion
US11384135B2 (en) * 2017-09-22 2022-07-12 Modern Meadow, Inc. Recombinant yeast strains

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986004353A1 (fr) * 1985-01-23 1986-07-31 Fraunhofer-Gesellschaft Zur Förderung Der Angewand Procede de regeneration intrasequentielle du co-facteur lors de syntheses enzymatiques, en particulier lors de la production de vitamine c
JPH0191785A (ja) * 1987-10-02 1989-04-11 Bitamin Kenkyusho:Kk Ｌ―グロノラクトン酸化酵素のクローン化ｄｎａ、該クローン化ｄｎａの組込まれた遺伝子組換えベクター及び該ベクターにより形質転換された宿主細胞
WO1997004100A2 (de) * 1995-07-17 1997-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. L-galactonatoxidoreduktase-ascorbinsäuresynthese

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986004353A1 (fr) * 1985-01-23 1986-07-31 Fraunhofer-Gesellschaft Zur Förderung Der Angewand Procede de regeneration intrasequentielle du co-facteur lors de syntheses enzymatiques, en particulier lors de la production de vitamine c
JPH0191785A (ja) * 1987-10-02 1989-04-11 Bitamin Kenkyusho:Kk Ｌ―グロノラクトン酸化酵素のクローン化ｄｎａ、該クローン化ｄｎａの組込まれた遺伝子組換えベクター及び該ベクターにより形質転換された宿主細胞
WO1997004100A2 (de) * 1995-07-17 1997-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. L-galactonatoxidoreduktase-ascorbinsäuresynthese

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 8920, Derwent World Patents Index; Class B04, AN 89-148142, XP002029312 *
EMBL Datenbank Eingabe SCREDUC 'Accession' Nummer X80642; 04 Dez 1995 MIOSGA T ET AL.:'A new yeast gene with homology to the aldo-keto reductase protein family' *
GENESEQ Datenbank Eingabe mit 'Accession' Nummer N92440: 30 Apr 1990 *
GENESEQ Datenbank Eingabe mit 'Accession' Nummer P91897: 30 Apr 1990 *
HALLER C -P ET AL: "ENZYMATIC SYNTHESIS OF L-ASCORBIC ACID 3. L-GALACTONO-GAMMA-LACTONE OXIDASE FROM YEASTS", DECHEMA BIOTECHNOLOGY CONFERENCE, vol. 4, 1990, pages 233 - 236, XP000646759 *
KULBE KD ET AL: "Enzymatic synthesis of L-ascorbic acid via D-uronic acids;membrane-reactor integrated recovery of D-galacturonic acid from pectin hydrolysates.", ANN N Y ACAD SCI, 1987, 506 P543-51, UNITED STATES, XP000646778 *
OECHSNER U ET AL.: "A nuclear yeast gene (CCY) encodes a polypeptide with high homology to a vertebrate eye lens protein", FEBS LETTERS, vol. 238, no. 1, 1988, AMSTERDAM NL, pages 123 - 128, XP000647862 *
PIR Datenbank Eingabe 'Accession' Nummer S61163; 23 Feb 1996 MIOSGA T ET AL.:'A new yeast gene with homology to the aldo-deto reductase protein family' *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105671106B (zh) * 2016-02-16 2021-06-11 珀莱雅化妆品股份有限公司 一种采用橄榄油发酵法制备鞘糖脂的方法

Also Published As

Publication number Publication date
WO1997029194A2 (de) 1997-08-14
DE19604798A1 (de) 1997-08-14
EP0879287A2 (de) 1998-11-25

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