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WO1997000665A1 - Dentifrices liquides - Google Patents

Dentifrices liquides Download PDF

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Publication number
WO1997000665A1
WO1997000665A1 PCT/EP1996/002568 EP9602568W WO9700665A1 WO 1997000665 A1 WO1997000665 A1 WO 1997000665A1 EP 9602568 W EP9602568 W EP 9602568W WO 9700665 A1 WO9700665 A1 WO 9700665A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
tooth cleaning
water
liquid
cleaning agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1996/002568
Other languages
German (de)
English (en)
Inventor
Peter Wülknitz
Amerigo Pastura
Hans Laska
Klaus Schumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Original Assignee
Henkel AG and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel AG and Co KGaA filed Critical Henkel AG and Co KGaA
Publication of WO1997000665A1 publication Critical patent/WO1997000665A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A61K8/8176—Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5422—Polymers characterized by specific structures/properties characterized by the charge nonionic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/594—Mixtures of polymers

Definitions

  • the invention relates to liquid tooth cleaning agents with a Ge content of polishing components, humectants and water-soluble binders, which can be removed from a flexible container in the form of drops and slowly penetrate the bristles when applied to a toothbrush without running off the toothbrush.
  • Liquid dentifrices have been known for a long time.
  • a particular problem is the production of storage-stable liquid preparations with a content of polishing bodies which, when stored for a prolonged period of time, neither show a settling of the polishing component on the floor nor a sharp increase in viscosity which makes it difficult to dispense from a flexible container.
  • the viscosity of such liquid tooth cleaning agents is preferably in a range from 2 to 50 Pa * s (20 ° C.), measured with a rotary viscometer.
  • Liquid tooth cleaning agents of this type are known, for example, from US Pat. No. 5,178,869 and from WO 94/01080.
  • Sodium bicarbonate sodium bicarbonate (so-called baking soda) has been known as a polishing component in dentifrices for many years.
  • DE-A-2347787 proposes toothpastes which contain sodium hydrogen carbonate together with smaller amounts of conventional polishing components.
  • Liquid tooth cleaning agents were already known from EP-A-0517319, but they only contained smaller amounts of dissolved sodium hydrogen carbonate in addition to chalk as polishing bodies.
  • the invention relates to a liquid dentifrice containing polishing components, humectants and water-soluble polymeric binders, characterized in that an alkali hydrogen carbonate is contained as the polishing component and a combination of a nonionic guar derivative and a polyvinylpyrrolidone is contained as the water-soluble polymeric binder.
  • a liquid tooth cleaning agent should be understood to be a preparation whose viscosity at 20 ° C. is in the range from 2 to 60 Pa * s, measured, for example, in a Brookfield Synchro Lectric RVF rotary viscometer.
  • the tooth cleaning agents according to the invention remain flowable even after prolonged storage, the polishing components do not settle and the flow behavior is very advantageous for use from a flexible dispensing container with a narrow opening, since the product is easy to remove and in the form of viscous drops has the toothbrush brought.
  • Sodium bicarbonate or a mixture of sodium and potassium bicarbonate is preferably used as the alkali bicarbonate.
  • the addition of potassium bicarbonate also improves the salty taste.
  • the alkali hydrogen carbonate is preferably used as a fine, anhydrous powder of commercial quality and with a particle size which is predominantly in the range from 0.001 to 0.4 mm.
  • the fine particle size of the hydrogen carbonate also has a favorable effect on the viscosity.
  • the sodium hydrogen carbonate should therefore preferably have at least 90% by weight of a grain size below 0.16 mm.
  • the alkali metal hydrogen carbonate can be present in an amount of 1 to 50% by weight in the liquid tooth cleaning agents according to the invention.
  • water-insoluble polishing components may also be present, for example silica polishing agents customary for dentifrices or aluminum hydroxide, calcium phosphates, polymetaphosphate, chalk or sodium aluminum silicate.
  • the dentifrices according to the invention preferably contain a combination of 5 to 25% by weight of alkali metal bicarbonate and 1 to 20% by weight of silica polishing agents.
  • Suitable silicic acid polishing agents are gel silicas and precipitated silicas.
  • guar derivative an etherification of the guar gum with alkylene oxides, e.g. hydroxyalkyl guar obtained with ethylene oxide or propylene oxide can be used.
  • alkylene oxides e.g. hydroxyalkyl guar obtained with ethylene oxide or propylene oxide
  • Such guar derivatives are indeed very good thickeners for aqueous preparations, when used in the liquid tooth cleaning agents according to the invention as the sole water-soluble binder they also lead to stable preparations, the viscosity behavior of which is, however, characterized by low fluidity and strong threading due to high structural viscosity . Surprisingly, it was found that this effect is avoided by using polyvinylpyrrolidone as the second water-soluble binder.
  • Suitable hydroxyalkyl guar is preferably hydroxypropyl guar, which is obtainable by adding propylene oxide to guar gum and is commercially available, for example, as Jaguar ( R ) HP-8 (degree of substitution 0.3-0.5).
  • Liquid tooth cleaning agents according to the invention preferably contain a combination of
  • inorganic and organic thickeners can also be present in the tooth cleaning agents according to the invention.
  • Particularly fine thickening silicas e.g. Silicas obtained by pyrolysis (type Aerosil), and layered silicates are used.
  • Other organic polymers are e.g. natural vegetable gums, swelling starch, water-soluble starch and cellulose derivatives, e.g. Carboxymethyl cellulose or hydroxyl ethyl starch.
  • Biopolymers such as Xanthan gum or succino-glycane are suitable as further thickeners.
  • the proportion of the further organic thickeners is preferably less than 0.5% by weight of the composition.
  • Polyols with 2 to 6 carbon atoms and 2 to 6 hydroxyl groups or polyalkylene glycols are suitable as humectants.
  • Suitable polyols are glycerol, sorbitol, 1,2-propylene glycol, polyethylene glycol and polypropylene glycol as well as ethylene oxide-propylene oxide block polymers and mixtures of these substances.
  • Liquid polyethylene glycols with molecular weights up to 800 are particularly suitable as polyethylene glycols. If sorbitol is used as a humectant, a particularly pure quality free of reducing sugars and disaccharides must be used in order to prevent disruptive discoloration or elimination.
  • the tooth cleaning agents according to the invention preferably contain glycerol, polyethylene glycol or a mixture of these substances in an amount of 30 to 80% by weight.
  • Water and optionally smaller amounts of ethanol or isopropanol may be present as further carrier components.
  • the water content is preferably below 25% by weight, the ethanol content should remain below 10% by weight.
  • the dentifrices according to the invention may contain the usual auxiliaries and additives, e.g.
  • surfactants e.g. Anionic surfactants in the form of their alkali metal or ammonium salts such as sodium lauryl sulfate or sodium lauryl ether sulfate, acyl sarcosinates, acyl isethionates, acyl (methyl) taurides or ether carboxylates, amphoteric and zwitterionic surfactants such as e.g. Cocoamphoglycinate or cocoamido propyl betaine, amine oxide surfactants, nonionic surfactants such as e.g. Fatty alcohol polyglycol ether, fatty acid (mono) glycerides and their oxethylates or fatty acid oxethylates or alkyl (oligo) glucosides.
  • Anionic surfactants in the form of their alkali metal or ammonium salts such as sodium lauryl sulfate or sodium lauryl ether sulfate,
  • Flavors and plant extracts such as Peppermint oil, spearmint oil, eucalyptus oil, anise oil, fennel oil, caraway oil, menthyl acetate, cinnamon aldehyde, vanilla, thymol or flavorings with strawberry, raspberry, pineapple, apple, orange or kiwi flavor
  • Sweeteners such as Na saccharinate, K-acesulfame, cyclamate, aspartame and others
  • water-soluble fluorine compounds such as e.g. Sodium fluoride, monofluorophosphate, tin fluoride, amine fluoride,
  • pH adjusting agents such as mono-, di- and trialkali metal phosphates, citric acid / Na citrate, lactic acid / Na lactate, Anti-tartar active ingredients, e.g. di- and polyphosphonates (e.g. 2-hydroxyethane-2,2-diphosphonate) or polyphosphates (e.g. tetrasodium pyrophosphate, pentasodium triphosphate)
  • antimicrobial substances such as Triclosan, biguanides (such as chlorhexidine) and other quaternary ammonium compounds,
  • Dyes, pigments and opacifiers e.g. titanium dioxide, zinc oxide.
  • liquid dentifrices according to the invention preferably contain
  • additives from the group of surface-active substances, aromas, sweeteners, fluorine compounds and their mixtures.
  • the liquid dentifrices according to the invention are produced, for example, in such a way that the polishing components are dispersed in the greater part of the humectants, the binders are dispersed in the remaining humectants (and, if present, are brought into solution with part of the water) and then the po Body dispersion with the binder dispersion and with the solution of the surfactants, the fluorine compounds and the sweeteners in Water or its dispersion in polyol and with a solution of the aromatic oil, an emulsifier and possibly ethanol is combined and mixed.
  • Liquid tooth cleaning agents were produced according to the following recipe examples:
  • Titanium dioxide 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5
  • Polyethylene glycol (MW: 400) 8.0 8.0 8.0 8.0 8.0 8.0 8.0
  • Carbopol 980 0.1 - - - - - - -
  • Tagat S 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5
  • Titanium dioxide 0.5 0.5 0.5 0.5 0.5 0.5
  • Luviskol K30 poly-N-vinylpyrrolidone (-2), molecular weight approx.40,000, K value (1%) 30 + 4
  • Carbopol 980 polyaeric acid, cross-linked; Acid number 700 - 750
  • Keltrol F xanthan gum (food-grade)
  • Texapon K 1296 sodium lauryl sulfate
  • Tego-Betain BL 215 Cocoamidopropyl-betaine (1-Ci2-i8-Alcylamido-3-dimethylaminopropane-3-carboxymethylbetaine), 30% by weight (NaCl: 5% by weight) in water
  • Tagat S polyoxyethylene (20) glycerol monostearate
  • the dentifrices were produced using the following procedure:
  • the polishing components NaHC03, KHCO3, silicas
  • TiO2 were mixed with glycerin to a homogeneous slurry.
  • the water-soluble binders PVP, hydroxypropyl guar
  • the surfactants (Texapon K 1296, Tego-Betain), saccharin-Na and NaF were dissolved in the remaining water.
  • the aromatic oil and the Emulsifier (Tagat S) was dissolved in ethanol. Finally, the surfactant solution, the binder solution and the aroma oil solution were successively mixed into the polishing paste and the mixture was deaerated.
  • the viscosity measurement was carried out with a Brookfield Synchro Lectric, RVF, rotary viscometer using spindle No. 3 at 4 RPM.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne des dentifrices liquides qui contiennent comme constituant de polissage entre 1 et 60 % en poids de bicarbonate de sodium, ainsi que des liants solubles dans l'eau et des agents permettant de maintenir un degré d'humidification, et dont la viscosité est comprise entre 2 et 50 P.s (20 °C). Afin d'ajuster une viscoélasticité favorable sur le plan de l'application technique, on utilise comme liant une combinaison d'hydroxypropyle-guar et de polyvinylpyrrolidone. Ces dentifrices liquides contiennent également de préférence des agents de polissage insolubles dans l'eau, de préférence de l'acide silicique.
PCT/EP1996/002568 1995-06-22 1996-06-14 Dentifrices liquides Ceased WO1997000665A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19522750.6 1995-06-22
DE1995122750 DE19522750A1 (de) 1995-06-22 1995-06-22 Flüssige Zahnreinigungsmittel

Publications (1)

Publication Number Publication Date
WO1997000665A1 true WO1997000665A1 (fr) 1997-01-09

Family

ID=7765035

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/002568 Ceased WO1997000665A1 (fr) 1995-06-22 1996-06-14 Dentifrices liquides

Country Status (2)

Country Link
DE (1) DE19522750A1 (fr)
WO (1) WO1997000665A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100305622B1 (ko) * 1997-08-28 2001-11-15 조지안느 플로 농축필름-형성조성물
US6465107B1 (en) 1996-09-13 2002-10-15 Dupont Canada Inc. Silicone-containing polyolefin film
EP1040821B2 (fr) † 1999-03-31 2005-10-12 L'oreal Composition cosmétique comprenant au moins une phase pulvérulente, un hydratant et un dérivé de galactomannane et utilisations
WO2006013081A1 (fr) * 2004-08-02 2006-02-09 Glaxo Group Limited Nouvelle composition pour la xérostomie
WO2017194901A1 (fr) * 2016-05-13 2017-11-16 Bochenek Stéphane Gel de blanchiment sans peroxydes

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19646985A1 (de) * 1996-11-14 1998-06-04 Michael Dr Weichsel Geschmacksverbesserung bei Zahnregulierungsapparaten
FR2767684B1 (fr) 1997-08-28 1999-10-01 Oreal Composition demaquillante
DE19845247A1 (de) * 1998-10-01 2000-04-06 Henkel Kgaa Flüssiges Zahnreinigungsgel
US6451291B1 (en) * 2000-10-11 2002-09-17 Colgate Palmolive Company Surfactant system for increasing dental tissue antibacterial agent uptake
JP2023522600A (ja) * 2020-04-20 2023-05-31 ザ プロクター アンド ギャンブル カンパニー シリカ及び界面活性ポリマーを含む練り歯磨き組成物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2188548A (en) * 1986-04-05 1987-10-07 Beecham Group Plc Oral hygiene compositions
EP0517319A1 (fr) * 1991-06-04 1992-12-09 Unilever N.V. Dentifrice liquide
WO1994001080A2 (fr) * 1992-07-10 1994-01-20 Henkel Kommanditgesellschaft Auf Aktien Dentifrice liquide
US5302373A (en) * 1993-06-10 1994-04-12 Church & Dwight Co., Inc. Liquid mouthwash containing a particulate bicarbonate suspension
DE9410733U1 (de) * 1994-07-05 1994-10-13 Dental-Kosmetik Gmbh Dresden, 01099 Dresden Mundspüllösung mit Baking Soda

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2188548A (en) * 1986-04-05 1987-10-07 Beecham Group Plc Oral hygiene compositions
EP0517319A1 (fr) * 1991-06-04 1992-12-09 Unilever N.V. Dentifrice liquide
WO1994001080A2 (fr) * 1992-07-10 1994-01-20 Henkel Kommanditgesellschaft Auf Aktien Dentifrice liquide
US5302373A (en) * 1993-06-10 1994-04-12 Church & Dwight Co., Inc. Liquid mouthwash containing a particulate bicarbonate suspension
DE9410733U1 (de) * 1994-07-05 1994-10-13 Dental-Kosmetik Gmbh Dresden, 01099 Dresden Mundspüllösung mit Baking Soda

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465107B1 (en) 1996-09-13 2002-10-15 Dupont Canada Inc. Silicone-containing polyolefin film
KR100305622B1 (ko) * 1997-08-28 2001-11-15 조지안느 플로 농축필름-형성조성물
EP1040821B2 (fr) † 1999-03-31 2005-10-12 L'oreal Composition cosmétique comprenant au moins une phase pulvérulente, un hydratant et un dérivé de galactomannane et utilisations
WO2006013081A1 (fr) * 2004-08-02 2006-02-09 Glaxo Group Limited Nouvelle composition pour la xérostomie
AU2005268926B2 (en) * 2004-08-02 2011-10-13 Glaxosmithkline Consumer Healthcare (Uk) Ip Limited Novel composition for xerostomia
US9044500B2 (en) 2004-08-02 2015-06-02 Glaxosmithkline Consumer Healthcare Gmbh & Co Kg Composition for xerostomia
US10350238B2 (en) 2004-08-02 2019-07-16 Glaxosmithkline Consumer Healthcare Holdings (Us) Llc Method of treating xerostomia
WO2017194901A1 (fr) * 2016-05-13 2017-11-16 Bochenek Stéphane Gel de blanchiment sans peroxydes
FR3051113A1 (fr) * 2016-05-13 2017-11-17 Stephane Bochenek Gel de blanchiment sans peroxydes.

Also Published As

Publication number Publication date
DE19522750A1 (de) 1997-01-02

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