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WO1996024345A3 - Utilisations d'une vitamine du groupe k contre une perte des facultes cognitives - Google Patents

Utilisations d'une vitamine du groupe k contre une perte des facultes cognitives Download PDF

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Publication number
WO1996024345A3
WO1996024345A3 PCT/DE1996/000183 DE9600183W WO9624345A3 WO 1996024345 A3 WO1996024345 A3 WO 1996024345A3 DE 9600183 W DE9600183 W DE 9600183W WO 9624345 A3 WO9624345 A3 WO 9624345A3
Authority
WO
WIPO (PCT)
Prior art keywords
vitamin
substance
group
blood
loss
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE1996/000183
Other languages
German (de)
English (en)
Other versions
WO1996024345A2 (fr
Inventor
Martin Kohlmeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19504003A external-priority patent/DE19504003A1/de
Application filed by Individual filed Critical Individual
Priority to AU46186/96A priority Critical patent/AU4618696A/en
Priority to EP96901702A priority patent/EP0759748A1/fr
Publication of WO1996024345A2 publication Critical patent/WO1996024345A2/fr
Publication of WO1996024345A3 publication Critical patent/WO1996024345A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne un nouvel emploi d'une vitamine du groupe K ou d'une substance influant sur le transport d'une vitamine du groupe K, ou bien d'une substance activant la régénération d'une vitamine du groupe K, afin de produire une préparation active contre une perte accélérée des facultés cognitives, notamment contre les effets de la maladie d'Alzheimer. Pour fabriquer une préparation permettant d'évaluer le risque d'apparition d'une perte accélérée des facultés cognitives ou de lutter contre la maladie d'Alzheimer, l'invention préconise également l'utilisation d'une substance capable de déterminer la concentration de vitamine K dans le sang ou d'autres fluides organiques, l'utilisation d'une substance susceptible de déterminer la proportion de restes glutamate carboxylés dans des protéines vitamine K-dépendantes, dans le sang ou d'autres fluides organiques, et l'utilisation d'une substance susceptible de déterminer la concentration de η-carboxyglutamate dans le sang ou d'autres fluides organiques ou bien dans les excrétions.
PCT/DE1996/000183 1995-02-08 1996-02-07 Utilisations d'une vitamine du groupe k contre une perte des facultes cognitives Ceased WO1996024345A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU46186/96A AU4618696A (en) 1995-02-08 1996-02-07 Uses of a vitamin of the k-group against a loss of cognitive faculties
EP96901702A EP0759748A1 (fr) 1995-02-08 1996-02-07 Utilisations d'une vitamine du groupe k contre une perte des facultes cognitives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19504003.1 1995-02-08
DE19504003A DE19504003A1 (de) 1995-02-08 1995-02-08 Verwendungen eines Vitamins der K-Gruppe

Publications (2)

Publication Number Publication Date
WO1996024345A2 WO1996024345A2 (fr) 1996-08-15
WO1996024345A3 true WO1996024345A3 (fr) 1997-02-20

Family

ID=7753374

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1996/000183 Ceased WO1996024345A2 (fr) 1995-02-08 1996-02-07 Utilisations d'une vitamine du groupe k contre une perte des facultes cognitives

Country Status (4)

Country Link
EP (1) EP0759748A1 (fr)
AU (1) AU4618696A (fr)
DE (1) DE19549262C2 (fr)
WO (1) WO1996024345A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101646429B (zh) * 2007-04-05 2012-08-29 J-制油株式会社 镇定剂及功能性食品

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0366480A2 (fr) * 1988-10-27 1990-05-02 Bar Ilan University Méthode et compositions de traitement de la maladie d'Alzheimer, de démences apparentées et de l'épilepsie
US5059627A (en) * 1989-08-24 1991-10-22 Takeda Chemical Industries, Ltd. Nerve growth factor secretion inducing composition
WO1991016047A1 (fr) * 1990-04-17 1991-10-31 Allergan, Inc. Methyle 5-hydroxy-2-(5h)-furanones a substitution oxygene, soufre ou azote en position 4, utilisees comme agents anti-inflammatoires
JPH06340526A (ja) * 1993-06-02 1994-12-13 Mitsui Toatsu Chem Inc 置換１，４−ナフトキノン誘導体を有効成分として含有する神経成長因子産生、分泌誘発剤
EP0629400A1 (fr) * 1993-06-18 1994-12-21 Takeda Chemical Industries, Ltd. Compositions contenant de l'idebenone pour le traitement de la maladie d'Alzheimer
WO1995001096A1 (fr) * 1993-06-29 1995-01-12 Shapiro Howard K Compositions pharmaceutiques et leur utilisation pour le traitement d'affections neurologiques et de symptomologies a etiologies associees

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438208A (en) * 1982-05-27 1984-03-20 The Regents Of The University Of California Region-specific determinants for vitamin K dependent bone protein
EP0118256B1 (fr) * 1983-03-04 1992-05-13 Scripps Clinic And Research Foundation Immunoadsorbant et procédé de récupération de protéines dépendantes de la vitamine-K utilisant cet adsorbant
US5262332A (en) * 1989-04-05 1993-11-16 Brigham And Women's Hospital Diagnostic method for Alzheimer's disease: examination of non-neural tissue
FR2678638A1 (fr) * 1991-07-03 1993-01-08 Inst Nat Sante Rech Med Anticorps polyclonaux et monoclonaux contre la proteine tau pour le diagnostic de la maladie d'alzheimer.

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0366480A2 (fr) * 1988-10-27 1990-05-02 Bar Ilan University Méthode et compositions de traitement de la maladie d'Alzheimer, de démences apparentées et de l'épilepsie
US5059627A (en) * 1989-08-24 1991-10-22 Takeda Chemical Industries, Ltd. Nerve growth factor secretion inducing composition
WO1991016047A1 (fr) * 1990-04-17 1991-10-31 Allergan, Inc. Methyle 5-hydroxy-2-(5h)-furanones a substitution oxygene, soufre ou azote en position 4, utilisees comme agents anti-inflammatoires
JPH06340526A (ja) * 1993-06-02 1994-12-13 Mitsui Toatsu Chem Inc 置換１，４−ナフトキノン誘導体を有効成分として含有する神経成長因子産生、分泌誘発剤
EP0629400A1 (fr) * 1993-06-18 1994-12-21 Takeda Chemical Industries, Ltd. Compositions contenant de l'idebenone pour le traitement de la maladie d'Alzheimer
WO1995001096A1 (fr) * 1993-06-29 1995-01-12 Shapiro Howard K Compositions pharmaceutiques et leur utilisation pour le traitement d'affections neurologiques et de symptomologies a etiologies associees

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 9509, Derwent World Patents Index; AN 95-063774, XP002011185 *
M.J. SHEARER: "Vitamin K metabolism and nutriture", BLOOD REV., vol. 6, no. 2, 1992, pages 92 - 104, XP002011184 *
R.B. RUCKER ET AL.: "New perspectives on function of vitamins", NUTRITION, vol. 10, no. 6, 1994, pages 507 - 513, XP002011183 *

Also Published As

Publication number Publication date
WO1996024345A2 (fr) 1996-08-15
DE19549262C2 (de) 1997-10-09
EP0759748A1 (fr) 1997-03-05
DE19549262A1 (de) 1996-09-05
AU4618696A (en) 1996-08-27

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