[go: up one dir, main page]

WO1996022372A3 - Antibodies for the control of cyst nematodes and transgenic plants expressing them - Google Patents

Antibodies for the control of cyst nematodes and transgenic plants expressing them Download PDF

Info

Publication number
WO1996022372A3
WO1996022372A3 PCT/NL1996/000033 NL9600033W WO9622372A3 WO 1996022372 A3 WO1996022372 A3 WO 1996022372A3 NL 9600033 W NL9600033 W NL 9600033W WO 9622372 A3 WO9622372 A3 WO 9622372A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibodies
control
cyst nematodes
transgenic plants
plants expressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/NL1996/000033
Other languages
French (fr)
Other versions
WO1996022372A2 (en
Inventor
Jacob Bakker
Arjen Schots
Wilhelmus Johannes Stiekema
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
De Rijkslandbouwhogeschool
Original Assignee
De Rijkslandbouwhogeschool
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by De Rijkslandbouwhogeschool filed Critical De Rijkslandbouwhogeschool
Priority to JP8522176A priority Critical patent/JPH11511644A/en
Priority to CA002241977A priority patent/CA2241977A1/en
Priority to PCT/NL1996/000033 priority patent/WO1996022372A2/en
Priority to EP96902500A priority patent/EP0871731A2/en
Publication of WO1996022372A2 publication Critical patent/WO1996022372A2/en
Publication of WO1996022372A3 publication Critical patent/WO1996022372A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention concerns antibodies directed against an antigenic subventral salivary protein of a cyst nematode, e.g. of the genera Heterodera, Globodera and Punctodera, or at an immunogenic part or equivalent thereof, said antigenic protein having an amino acid of 30-50 kDa and having an isoelectric point (pI) of about 6.8 to 8.7. Furthermore provided are expression systems comprising at least a nucleotide sequence encoding an antibody or antibody fragment against a cyst nematode salivary protein, and a sequence regulating expression of said nucleotide sequence, for transforming plants so as to protect them against cyst nematodes.
PCT/NL1996/000033 1995-01-17 1996-01-17 Antibodies for the control of cyst nematodes and transgenic plants expressing them Ceased WO1996022372A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP8522176A JPH11511644A (en) 1995-01-17 1996-01-17 Antibodies for controlling cyst nematodes and transgenic plants expressing them
CA002241977A CA2241977A1 (en) 1995-01-17 1996-01-17 Antibodies for the control of cyst nematodes and transgenic plants expressing them
PCT/NL1996/000033 WO1996022372A2 (en) 1995-01-17 1996-01-17 Antibodies for the control of cyst nematodes and transgenic plants expressing them
EP96902500A EP0871731A2 (en) 1995-01-17 1996-01-17 Antibodies for the control of cyst nematodes and transgenic plants expressing them

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95200110 1995-01-17
CA002241977A CA2241977A1 (en) 1995-01-17 1996-01-17 Antibodies for the control of cyst nematodes and transgenic plants expressing them
PCT/NL1996/000033 WO1996022372A2 (en) 1995-01-17 1996-01-17 Antibodies for the control of cyst nematodes and transgenic plants expressing them

Publications (2)

Publication Number Publication Date
WO1996022372A2 WO1996022372A2 (en) 1996-07-25
WO1996022372A3 true WO1996022372A3 (en) 1996-09-19

Family

ID=27170748

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL1996/000033 Ceased WO1996022372A2 (en) 1995-01-17 1996-01-17 Antibodies for the control of cyst nematodes and transgenic plants expressing them

Country Status (3)

Country Link
EP (1) EP0871731A2 (en)
CA (1) CA2241977A1 (en)
WO (1) WO1996022372A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998001569A1 (en) * 1996-07-08 1998-01-15 Rijkslandbouwuniversiteit Wageningen Cellulases
US5990385A (en) * 1997-11-10 1999-11-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Protein production in transgenic alfalfa plants
AU8751898A (en) * 1998-07-31 2000-02-21 Centrum Voor Plantenveredelings- En Reproduktieonderzoek (Cpro - Dlo) Engineering nematode resistance in solanacae
BR0113512A (en) 2000-08-25 2005-05-10 Basf Plant Science Gmbh Plant polynucleotides encoding new prenyl proteases
FR3065621B1 (en) * 2017-04-28 2020-07-31 Philippe Baron D PRODUCT FOR THE TREATMENT OF PLANTS AND FOR THE FIGHT AGAINST CERTAIN BIOAGRESSORS, IN PARTICULAR APPETIZERS, AND MANUFACTURING METHODS
FR3052336A1 (en) * 2016-06-08 2017-12-15 Philippe Baron D PLANT TREATMENT PRODUCT AND FOR CONTROLLING CERTAIN BIOAGRESSORS, IN PARTICULAR SUCKS, AND MANUFACTURING METHODS
WO2017212127A1 (en) * 2016-06-08 2017-12-14 Denis Baron Product for treating plants and combating certain pests, in particular aphids, and method for producing same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8601642A (en) * 1986-06-24 1988-01-18 Rijkslandbouwhogeschool New potato root eel-worm proteins - and antibodies useful for determn. of eel-worm populations in soil
WO1992004453A1 (en) * 1990-09-10 1992-03-19 The University Of Leeds Plant parasitic nematode control

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8601642A (en) * 1986-06-24 1988-01-18 Rijkslandbouwhogeschool New potato root eel-worm proteins - and antibodies useful for determn. of eel-worm populations in soil
WO1992004453A1 (en) * 1990-09-10 1992-03-19 The University Of Leeds Plant parasitic nematode control

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
AKOLKAR,P.N., ET AL.: "Different V-L and V-H germ-line genes are used to produce similar combining sites with specificity for alpha-(1->6) dextrans", J. IMMUNOL. 138:4472-4479(1987), XP002002328 *
BACKETT, K.D., ET AL.: "STAGE-SPECIFIC MONOCLONAL ANTIBODIES TO THE POTATO CSYT NEMATODE GLOBODERA PALLIDA (STONE) BEHRENS", JOURNAL OF NEMATOLOGY, vol. 25, no. 3, pages 395 - 400, XP002002335 *
BURROWS, P.R., ET AL.: "CELLULAR AND MOLECULAR APPROACHES TO THE CONTROL OF PLANT PARASITIC NEMATODES", PLANT PARASITIC NEMATODES IN TEMPERATE AGRICULTURE . EVANS, K., ET AL. EDS., CAB INTERNATIONAL. CHAPTER 17., pages 609 - 630, XP002002337 *
DE BOER J. M., ET AL.: "Secretory granule proteins from the subventral esophageal glands of the potato cyst nematode identified by monoclonal antibodies to a protein fraction from second-stage juveniles", MOL. PLANT-MICROBE INTERACT. (1996), 9(1), 39-46, XP000570632 *
GOVERSE, A., ET AL.: "MONOCLONAL ANTIBODIES TO THE ESOPHAGEAL GLANDS AND STYLET SECRETIONS OF HETERODERA GLYCINES", JOURNAL OF NEMATOLOGY, vol. 26, no. 3, pages 251 - 259, XP002002336 *
MATSUDA, T., ET AL. AL.: "Variable region cDNA sequences and antigen binding specificity of mouse monoclonal antibodies to isomaltosyl oligosaccharides coupled to proteins", J. IMMUNOL. 142:863-870(1989), XP002002329 *
PANKA D.J., ET AL: "Variable region framework differences result in decreased or increased affinity of variant anti-digoxin antibodies", PROC. NATL. ACAD. SCI. U.S.A. 85:3080-3084(1988)., XP002002327 *
ROBINSON M P, ET AL.: "Characterisation of a 34 kD protein from potato cyst nematodes, using monoclonal antibodies with potential for species diagnosis.", ANNALS OF APPLIED BIOLOGY 123 (2). 1993. 337-347., XP002002332 *
SCHOTS, A., ET AL.: "Plantibodies: a flexible approach to design resistance against pathogens", NETH. J. PL. PATHOL. SUPPLEMENT 2., pages 183 - 191, XP002002331 *
SCHOTS, A., ET AL.: "SEROLOGICAL DIFFERENTIATION OF THE POTATO-CYST NEMATODES GLOBODERA PALLIDA NAD G.ROSTOCHIENSIS: II. PREPARATION AND CHARACTERIZATION OF SPECIES SPECIFIC MONOCLONAL ANTIBODIES", HYBRIDOMA, vol. 8, no. 4, pages 401 - 413, XP002002334 *
SIJMONS, P.C., ET AL.: "Parasitic strategies of root nematodes and associated host cell responses", ANN. REV. PHYTOPATHOL., vol. 32, 1994, pages 235 - 259, XP000567306 *
SIJMONS, P.C.: "Plant-nematode interactions", PLANT MOLECULAR BIOLOGY, vol. 23, pages 917 - 931, XP002002333 *
TAVLADORAKI, P., ET AL.: "Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack", NATURE, vol. 366, 2 December 1993 (1993-12-02), pages 469 - 472, XP000421325 *

Also Published As

Publication number Publication date
CA2241977A1 (en) 1996-07-25
EP0871731A2 (en) 1998-10-21
WO1996022372A2 (en) 1996-07-25

Similar Documents

Publication Publication Date Title
AU4041995A (en) Immunogenic hybrid protein OprF-OprL derived from Pseudomonas aeruginosa membrane proteins
NO964650D0 (en) LAG-3 protein-soluble polypeptide fractions, method of preparation, therapeutic preparation and anti-idiotype antibody
ES2129487T3 (en) SYNTHETIC PEPTIDES, ANTIBODIES DIRECTED AGAINST THEM AND THEIR USE.
CA2168011A1 (en) Hybrid toxin
DE69328489D1 (en) STRESS PROTEINS EPITOPES
ATE317904T1 (en) OVEREXPRESSION OF PHYTASE IN YEAST SYSTEMS
BR1100704KB1 (en) recombinant vector, method for producing a DNA, method for producing a polypeptide, methods using said polypeptide, and a strain of Escherichia coli.
CY1106806T1 (en) DNA AND HUMAN TSLP POLYPEPTIDES
ES2087323T3 (en) METHOD FOR PRODUCING CYSTEINE-FREE PEPTIDES.
DK0832258T3 (en) Upstream activator sequences and recombinant promoter sequences that are functional in Yarrowia and vectors containing these
WO1996022372A3 (en) Antibodies for the control of cyst nematodes and transgenic plants expressing them
WO1997031116A3 (en) Recombinant ribonuclease proteins
AU5874999A (en) Immunoglobulin binding protein
EA201001190A1 (en) ISOLATED ANTIBODY, SPECIFICALLY ASSOCIATED WITH POLYPEPTIDE, CONTAINING FROM THE SEQUENCE OF AMINO ACID RESIDUES
DE69937570D1 (en) TRANSFORMING GROWTH FACTOR BETA-9 (ZTGFSS9) FROM MAMMALS
ATE353971T1 (en) IMPROVED PROCARIOTIC PROTEIN EXPRESSION
DK0773999T3 (en) OR-1, an orphan receptor belonging to the nuclear receptor family
WO2002074799A3 (en) Pepsin-sensitive modified bacillus thuringiensis insecticidal toxin
NZ241280A (en) Recombinant iga protease with a modified non-functional c-terminal protein sequence
MX9206732A (en) NEW TROMBINE INHIBITING PROTEINS FROM SANGUIJUELAS DE TIERRA.
DK1847607T3 (en) Antibodies to p51 protein
WO2003025191A3 (en) Pseudotyped retroviral vector system
CA2245804A1 (en) Recombinant ribonuclease proteins
WO1994025594A3 (en) Cloning, expression and vaccine composition corresponding to a peptide antigen of toxoplasma gondii

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1996902500

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2241977

Country of ref document: CA

Ref country code: CA

Ref document number: 2241977

Kind code of ref document: A

Format of ref document f/p: F

ENP Entry into the national phase

Ref country code: JP

Ref document number: 1996 522176

Kind code of ref document: A

Format of ref document f/p: F

WWP Wipo information: published in national office

Ref document number: 1996902500

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1996902500

Country of ref document: EP