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WO1996019205B1 - Systeme de liberation transdermique avec opercule adhesif et rondelle pelable - Google Patents

Systeme de liberation transdermique avec opercule adhesif et rondelle pelable

Info

Publication number
WO1996019205B1
WO1996019205B1 PCT/US1995/016498 US9516498W WO9619205B1 WO 1996019205 B1 WO1996019205 B1 WO 1996019205B1 US 9516498 W US9516498 W US 9516498W WO 9619205 B1 WO9619205 B1 WO 9619205B1
Authority
WO
WIPO (PCT)
Prior art keywords
peel seal
backing layer
active agent
seal disc
adhesive
Prior art date
Application number
PCT/US1995/016498
Other languages
English (en)
Other versions
WO1996019205A1 (fr
Filing date
Publication date
Application filed filed Critical
Priority to EP95943869A priority Critical patent/EP0799029A1/fr
Priority to JP8519931A priority patent/JPH10511353A/ja
Priority to AU45233/96A priority patent/AU695170B2/en
Publication of WO1996019205A1 publication Critical patent/WO1996019205A1/fr
Publication of WO1996019205B1 publication Critical patent/WO1996019205B1/fr
Priority to MXPA/A/1997/004291A priority patent/MXPA97004291A/xx

Links

Abstract

Dispositif (10) conçu pour appliquer une substance active sur la peau ou les muqueuses d'un individu, qui est constitué des parties suivantes: un composite laminaire d'un opercule adhésif (26), une couche dorsale (14) sur laquelle repose la partie centrale de l'opercule, une membrane active (16) perméable à la substance administrée, la couche dorsale et la membrane qui délimitent un réceptacle (12) contenant la formulation de la substance active, une rondelle pelable (20) sur laquelle repose la membrane active perméable à la substance, un joint à thermoscellage (22) sur le pourtour de la rondelle pelable. La membrane active perméable à la substance, la couche dorsale et un revêtement intérieur amovible (24) de diffusion sont à la base de la partie exposée de l'opercule et de la rondelle pelable. Le revêtement adhésif est placé au-dessus et en bordure de la trajectoire de la substance active vers la peau et les muqueuses et il est protégé de la dégradation des composants du réceptacle par plusieurs joints à thermoscellage. La rondelle pelable sert de protection contre la diffusion de la substance active contenue dans le réceptacle et le revêtement intérieur de diffusion empêche la partie adhésive d'être exposée à l'environnement extérieur avant toute utilisation.
PCT/US1995/016498 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable WO1996019205A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP95943869A EP0799029A1 (fr) 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable
JP8519931A JPH10511353A (ja) 1994-12-21 1995-12-08 接着剤オーバーレイおよび剥離性シールディスクを用いた経皮送達システム
AU45233/96A AU695170B2 (en) 1994-12-21 1995-12-08 Transdermal delivery system with adhesive overlay and peel seal disc
MXPA/A/1997/004291A MXPA97004291A (en) 1994-12-21 1997-06-10 System of release transdermica conrecubrimiento adhesivo and disco de selladodesprendi

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36180094A 1994-12-21 1994-12-21
US08/361,800 1994-12-21

Publications (2)

Publication Number Publication Date
WO1996019205A1 WO1996019205A1 (fr) 1996-06-27
WO1996019205B1 true WO1996019205B1 (fr) 1996-08-08

Family

ID=23423499

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/016498 WO1996019205A1 (fr) 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable

Country Status (9)

Country Link
US (1) US5662925A (fr)
EP (1) EP0799029A1 (fr)
JP (1) JPH10511353A (fr)
CN (1) CN1170360A (fr)
AU (1) AU695170B2 (fr)
CA (1) CA2208132A1 (fr)
TW (1) TW438607B (fr)
WO (1) WO1996019205A1 (fr)
ZA (1) ZA9510786B (fr)

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