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WO1996006604B1 - Procedes d'identification et de traitement de tumeurs resistantes - Google Patents

Procedes d'identification et de traitement de tumeurs resistantes

Info

Publication number
WO1996006604B1
WO1996006604B1 PCT/US1995/011125 US9511125W WO9606604B1 WO 1996006604 B1 WO1996006604 B1 WO 1996006604B1 US 9511125 W US9511125 W US 9511125W WO 9606604 B1 WO9606604 B1 WO 9606604B1
Authority
WO
WIPO (PCT)
Prior art keywords
mrp
use according
pages
compound
protein
Prior art date
Application number
PCT/US1995/011125
Other languages
English (en)
Other versions
WO1996006604A3 (fr
WO1996006604A2 (fr
Filing date
Publication date
Priority claimed from US08/298,644 external-priority patent/US5543428A/en
Priority claimed from DE19944432563 external-priority patent/DE4432563C2/de
Application filed filed Critical
Priority to US08/793,659 priority Critical patent/US6235785B1/en
Priority to AU35434/95A priority patent/AU3543495A/en
Priority to EP95932371A priority patent/EP0777472A2/fr
Priority to JP8508977A priority patent/JPH10505348A/ja
Publication of WO1996006604A2 publication Critical patent/WO1996006604A2/fr
Publication of WO1996006604A3 publication Critical patent/WO1996006604A3/fr
Publication of WO1996006604B1 publication Critical patent/WO1996006604B1/fr
Priority to US09/836,567 priority patent/US20020013370A1/en
Priority to US09/836,429 priority patent/US6673813B2/en

Links

Abstract

L'invention concerne un procédé d'identification et d'inversion de la résistance multiple aux anticancéreux d'une tumeur, qui consiste à administrer une certaine quantité de n'importe lequel des composés définis dans cette invention, cette quantité étant suffisante pour réaliser l'inversion de la résistance multiple aux anticancéreux.
PCT/US1995/011125 1994-08-31 1995-08-31 Procedes d'identification et de traitement de tumeurs resistantes WO1996006604A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US08/793,659 US6235785B1 (en) 1994-08-31 1995-08-31 Methods for identifying and treating resistant tumors
AU35434/95A AU3543495A (en) 1994-08-31 1995-08-31 Methods for identifying and treating resistant tumors
EP95932371A EP0777472A2 (fr) 1994-08-31 1995-08-31 Procedes d'identification et de traitement de tumeurs resistantes
JP8508977A JPH10505348A (ja) 1994-08-31 1995-08-31 耐性腫瘍の同定および治療方法
US09/836,567 US20020013370A1 (en) 1994-08-31 2001-04-17 Methods for identifying and treating resistant tumors
US09/836,429 US6673813B2 (en) 1994-08-31 2001-04-17 Methods for identifying and treating resistant tumors

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/298,644 US5543428A (en) 1994-08-31 1994-08-31 Method for treating resistant tumors
US08/298,644 1994-08-31
DE19944432563 DE4432563C2 (de) 1994-09-13 1994-09-13 Verwendung von amphiphilen Anionen zur Verminderung der Zytostatika-Resistenz durch Hemmung des durch das MRP-Protein vermittelten Membrantransports
DEP4432563.0 1994-09-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US08/793,659 Continuation-In-Part US6235785B1 (en) 1994-08-31 1995-08-31 Methods for identifying and treating resistant tumors

Publications (3)

Publication Number Publication Date
WO1996006604A2 WO1996006604A2 (fr) 1996-03-07
WO1996006604A3 WO1996006604A3 (fr) 1996-08-01
WO1996006604B1 true WO1996006604B1 (fr) 1996-09-12

Family

ID=25940080

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/011125 WO1996006604A2 (fr) 1994-08-31 1995-08-31 Procedes d'identification et de traitement de tumeurs resistantes

Country Status (6)

Country Link
US (3) US6235785B1 (fr)
EP (2) EP0777472A2 (fr)
JP (1) JPH10505348A (fr)
AU (1) AU3543495A (fr)
CA (1) CA2198752A1 (fr)
WO (1) WO1996006604A2 (fr)

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US6235785B1 (en) * 1994-08-31 2001-05-22 Eli Lilly And Company Methods for identifying and treating resistant tumors
EP1115427B1 (fr) * 1998-09-25 2003-12-03 Horst Lindhofer Utilisation de cellules tumorales avec un decalage temporel en combinaison avec des anticorps intacts pour l'immunisation
AU1916501A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
CA2408622A1 (fr) * 2000-05-09 2001-11-15 Creighton University Procedes servant a inhiber la proliferation et a induire l'apoptose dans des cellules cancereuses
PE20020453A1 (es) 2000-09-27 2002-06-06 Merck & Co Inc Derivados del acido benzopirancarboxilico para el tratamiento de la diabetes y los trastornos de lipidos
CA2427610A1 (fr) 2000-10-31 2002-08-08 Merck & Co., Inc. Derives d'acide benzopyranocarboxylique pour traiter le diabete et d'autres troubles lipidiques
WO2002066038A1 (fr) * 2001-02-20 2002-08-29 Bristol-Myers Squibb Company Traitement de tumeurs refractaires a l'aide de derives d'epothilone
EP3268085A4 (fr) 2015-03-13 2018-10-31 The Board of Trustees of The Leland Stanford Junior University Inhibition de ltb4 pour prévenir et traiter le lymphoedème humain
US10107437B2 (en) * 2015-09-15 2018-10-23 Mustang Sampling Llc Tooling friendly adapter for insertion probe access
US20190382363A1 (en) 2015-11-30 2019-12-19 Merck Sharp & Dohme Corp. Aryl sulfonamides as blt1 antagonists
EP3383869B1 (fr) 2015-11-30 2023-06-28 Merck Sharp & Dohme LLC Sulfonamides d'aryle utilisés en tant qu'antagonistes de blt1
WO2017095722A1 (fr) 2015-11-30 2017-06-08 Merck Sharp & Dohme Corp. Utilisation d'arylacylsulfonamides en tant qu'antagonistes de blt1
US10370368B2 (en) 2015-11-30 2019-08-06 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as BLT1 antagonists

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US4889871A (en) * 1987-05-29 1989-12-26 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
US5216024A (en) 1987-07-28 1993-06-01 Baylor College Of Medicine Cell growth inhibitors and methods of treating cancer and cell proliferative diseases
US5216172A (en) 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
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US5543428A (en) 1994-08-31 1996-08-06 Eli Lilly And Company Method for treating resistant tumors

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