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WO1995027040A1 - Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses - Google Patents

Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses Download PDF

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Publication number
WO1995027040A1
WO1995027040A1 PCT/US1994/003613 US9403613W WO9527040A1 WO 1995027040 A1 WO1995027040 A1 WO 1995027040A1 US 9403613 W US9403613 W US 9403613W WO 9527040 A1 WO9527040 A1 WO 9527040A1
Authority
WO
WIPO (PCT)
Prior art keywords
hemoglobin
bioreactor
stabilized
hollow fiber
lumens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1994/003613
Other languages
English (en)
Inventor
Randal A. Goffe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UniSyn Technologies Inc
Original Assignee
UniSyn Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UniSyn Technologies Inc filed Critical UniSyn Technologies Inc
Priority to PCT/US1994/003613 priority Critical patent/WO1995027040A1/fr
Priority to AU67669/94A priority patent/AU6766994A/en
Priority to PCT/US1994/008295 priority patent/WO1995027041A1/fr
Priority to CA002163618A priority patent/CA2163618A1/fr
Priority to JP7525645A priority patent/JPH08511173A/ja
Priority to AU73713/94A priority patent/AU7371394A/en
Priority to EP94922694A priority patent/EP0711339A1/fr
Publication of WO1995027040A1 publication Critical patent/WO1995027040A1/fr
Priority to NO954854A priority patent/NO954854L/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

On décrit un milieu de culture destiné à des bioréacteurs à fibres creuses, qui contient de l'hémoglobine stabilisée ou une émulsion d'un composé perfluoré. Le milieu de culture favorise l'absorption et l'utilisation de l'oxygène. L'efficacité du bioréacteur est ainsi améliorée.
PCT/US1994/003613 1994-04-01 1994-04-01 Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses Ceased WO1995027040A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
PCT/US1994/003613 WO1995027040A1 (fr) 1994-04-01 1994-04-01 Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses
AU67669/94A AU6766994A (en) 1994-04-01 1994-04-01 Culture media additives for hollow fiber bioreactors
PCT/US1994/008295 WO1995027041A1 (fr) 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs
CA002163618A CA2163618A1 (fr) 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs
JP7525645A JPH08511173A (ja) 1994-04-01 1994-07-26 バイオリアクターのための培養培地添加物
AU73713/94A AU7371394A (en) 1994-04-01 1994-07-26 Culture media additives for bioreactors
EP94922694A EP0711339A1 (fr) 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs
NO954854A NO954854L (no) 1994-04-01 1995-11-29 Kulturmedietilsetningsstoffer for bioreaktorer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/003613 WO1995027040A1 (fr) 1994-04-01 1994-04-01 Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses

Publications (1)

Publication Number Publication Date
WO1995027040A1 true WO1995027040A1 (fr) 1995-10-12

Family

ID=22242416

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1994/003613 Ceased WO1995027040A1 (fr) 1994-04-01 1994-04-01 Additifs pour un milieu de culture destine a des bioreacteurs a fibres creuses
PCT/US1994/008295 Ceased WO1995027041A1 (fr) 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US1994/008295 Ceased WO1995027041A1 (fr) 1994-04-01 1994-07-26 Additifs pour des milieux de culture destines a des bioreacteurs

Country Status (6)

Country Link
EP (1) EP0711339A1 (fr)
JP (1) JPH08511173A (fr)
AU (2) AU6766994A (fr)
CA (1) CA2163618A1 (fr)
NO (1) NO954854L (fr)
WO (2) WO1995027040A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255109B1 (en) * 1998-06-24 2001-07-03 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Nitric oxide-scavenging system for culturing oocytes, embryos, or other cells
WO2001002548A3 (fr) * 1999-07-01 2001-07-12 Glaxo Group Ltd Methode de propagation
WO2003040298A3 (fr) * 2001-07-30 2003-10-16 Wolfgang Fege Procede d'alimentation en oxygene de cultures de micro-organismes, de cultures de cellules organiques animales ou humaines et de cultures tissulaires ou d'organoides en cours de culture ou d'organes en cours de culture
EP2474554A3 (fr) * 2006-05-22 2012-10-03 The Regents of The University of California Compositions et procédés de fourniture d'oxygène

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU781265B2 (en) * 1999-09-30 2005-05-12 Unisearch Limited Method and apparatus for culturing cells
AUPQ319199A0 (en) * 1999-09-30 1999-10-28 Unisearch Limited Method and apparatus for culturing cells
WO2002022775A1 (fr) 2000-09-13 2002-03-21 Csir Dispositif bioreacteur
DK2421951T3 (da) 2009-04-23 2013-08-26 Hemarina Bioreaktor der anvender oxygen-bærende molekyler
CN102574901B (zh) * 2009-05-07 2016-08-03 埃玛里纳 新的血红蛋白及其用途
WO2012048298A2 (fr) 2010-10-08 2012-04-12 Caridianbct, Inc. Procédés et systèmes de culture et de récolte de cellules dans un système de bioréacteur à fibres creuses avec conditions de régulation
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
CN109415696A (zh) 2016-05-25 2019-03-01 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997396A (en) * 1973-07-02 1976-12-14 Monsanto Company Method for the in vitro propagation and maintenance of cells
US4833089A (en) * 1986-09-19 1989-05-23 Shimadzu Corporation Pressure incubator
US5180676A (en) * 1984-06-14 1993-01-19 Teijin Limited Method of cultivating animal or plant cells
US5223428A (en) * 1982-12-14 1993-06-29 Baxter International Inc. Method for in vitro culture of mammalian cells
US5232848A (en) * 1987-03-24 1993-08-03 W. R. Grace & Co.-Conn. Basal nutrient medium for cell culture

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264555A (en) * 1992-07-14 1993-11-23 Enzon, Inc. Process for hemoglobin extraction and purification

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997396A (en) * 1973-07-02 1976-12-14 Monsanto Company Method for the in vitro propagation and maintenance of cells
US5223428A (en) * 1982-12-14 1993-06-29 Baxter International Inc. Method for in vitro culture of mammalian cells
US5180676A (en) * 1984-06-14 1993-01-19 Teijin Limited Method of cultivating animal or plant cells
US4833089A (en) * 1986-09-19 1989-05-23 Shimadzu Corporation Pressure incubator
US5232848A (en) * 1987-03-24 1993-08-03 W. R. Grace & Co.-Conn. Basal nutrient medium for cell culture

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255109B1 (en) * 1998-06-24 2001-07-03 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Nitric oxide-scavenging system for culturing oocytes, embryos, or other cells
US6426219B2 (en) * 1998-06-24 2002-07-30 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Nitric oxide-scavenging system for culturing oocytes, embryos, or other cells
US6864086B2 (en) 1998-06-24 2005-03-08 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Nitric oxide-scavenging system for culturing oocytes, embryos, or other cells
WO2001002548A3 (fr) * 1999-07-01 2001-07-12 Glaxo Group Ltd Methode de propagation
US6780612B1 (en) 1999-07-01 2004-08-24 Smithkline Beecham Corporation Methods for the propagation of lytic organisms
WO2003040298A3 (fr) * 2001-07-30 2003-10-16 Wolfgang Fege Procede d'alimentation en oxygene de cultures de micro-organismes, de cultures de cellules organiques animales ou humaines et de cultures tissulaires ou d'organoides en cours de culture ou d'organes en cours de culture
EP2474554A3 (fr) * 2006-05-22 2012-10-03 The Regents of The University of California Compositions et procédés de fourniture d'oxygène
US8404631B2 (en) 2006-05-22 2013-03-26 The Regents Of The University Of California Compositions and methods for the delivery of oxygen
US8404632B2 (en) 2006-05-22 2013-03-26 The Regents Of The University Of California Compositions and methods for the delivery of nitric oxide
US9493526B2 (en) 2006-05-22 2016-11-15 The Regents Of The University Of California Compositions and methods for the delivery of oxygen
US9493527B2 (en) 2006-05-22 2016-11-15 The Regents Of The University Of California Compositions and methods for the delivery of nitric oxide
US10202428B2 (en) 2006-05-22 2019-02-12 The Regents Of The University Of California Compositions and methods for the delivery of oxygen

Also Published As

Publication number Publication date
JPH08511173A (ja) 1996-11-26
CA2163618A1 (fr) 1995-10-12
WO1995027041A1 (fr) 1995-10-12
NO954854D0 (no) 1995-11-29
AU6766994A (en) 1995-10-23
EP0711339A1 (fr) 1996-05-15
AU7371394A (en) 1995-10-23
NO954854L (no) 1995-11-29

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